iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-001771

Ensembl Protein ID

ENSAMEP00000019213.1

UniProt Accession

G1MIM8; G1MIM8_AILME

Genbank Protein ID

ENSAMEP00000019213

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01049409

Gene Name

RABGEF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000018176.1	ENSAMET00000019977.1	ENSAMEP00000019213.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/ZnF_A20	1.60e-18	66.4	147	181

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/ZnF_A20

   S: 1    dpskllCkkgCgfYGnpetngyCSkCyreelrrrr 35
           d+s+llCkkgCg+YGnp+++g+CSkC+ree++++r
   Q: 147  DQSELLCKKGCGYYGNPAWQGFCSKCWREEYHKAR 181
           79*******************************86 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

SRGGDSRRPD GAMSSSDAED DFLEPATPTA TQAGHALPLL PQERCAEFPA LRGPASPRAC 60
TGCVQRGPVL RHRAPPGAAR KHAASEGGES APGISGTHAL LQRPFGADCG DRPAACGTAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCACGGGGCG GAGACAGCCG TCGCCCAGAC GGTGCCATGT CCAGCTCCGA CGCTGAAGAC 60
GACTTTCTGG AGCCGGCCAC CCCGACGGCC ACGCAGGCAG GGCACGCGCT GCCCCTGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003123--VPS9
IPR002653--Znf_A20

PROSITE

PS51205--VPS9
PS51036--ZF_A20

Pfam

PF02204--VPS9
PF01754--zf-A20

SMART

SM00167--VPS9
SM00259--ZnF_A20

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005730--C:nucleolus
GO:0003677--F:DNA binding
GO:0017112--F:Rab guanyl-nucleotide exchange factor activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0050728--P:negative regulation of inflammatory response
GO:1900165--P:negative regulation of interleukin-6 secretion
GO:1900235--P:negative regulation of Kit signaling pathway
GO:0002686--P:negative regulation of leukocyte migration
GO:0043305--P:negative regulation of mast cell degranulation
GO:0001933--P:negative regulation of protein phosphorylation
GO:0046580--P:negative regulation of Ras protein signal transduction
GO:0048261--P:negative regulation of receptor-mediated endocytosis
GO:0006612--P:protein targeting to membrane
GO:0060368--P:regulation of Fc receptor mediated stimulatory signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000198	Aegilops tauschii	32.26	1.00e-20	94.40
IUUC-Atr-003154	Amborella trichopoda	36.52	4.00e-23	102.00
IUUC-Apl-004018	Anas platyrhynchos	82.35	0.00e+00	706.00
IUUC-Aca-005227	Anolis carolinensis	24.43	6.00e-09	56.20
IUUC-Aly-006138	Arabidopsis lyrata	35.45	4.00e-25	109.00
IUUC-Ath-006747	Arabidopsis thaliana	34.92	7.00e-25	108.00
IUUC-Ago-007776	Ashbya gossypii	26.81	5.00e-21	95.50
IUUC-Acl-008235	Aspergillus clavatus	38.07	2.00e-27	117.00
IUUC-Afl-008570	Aspergillus flavus	39.44	3.00e-29	123.00
IUUC-Afu-008815	Aspergillus fumigatus	38.07	1.00e-27	118.00
IUUC-Ani-009381	Aspergillus nidulans	37.50	5.00e-28	119.00
IUUC-Ang-009615	Aspergillus niger	30.41	7.00e-30	125.00
IUUC-Aor-010195	Aspergillus oryzae	40.96	2.00e-29	123.00
IUUC-Ate-010514	Aspergillus terreus	38.64	2.00e-28	120.00
IUUC-Ame-011365	Astyanax mexicanus	64.10	4.00e-156	544.00
IUUC-Bgr-012102	Blumeria graminis	32.54	1.00e-27	118.00
IUUC-Bta-013124	Bos taurus	88.21	0.00e+00	753.00
IUUC-Bci-013943	Botrytis cinerea	34.13	2.00e-28	121.00
IUUC-Bdi-014539	Brachypodium distachyon	34.70	2.00e-26	113.00
IUUC-Bol-016580	Brassica oleracea	37.57	2.00e-29	124.00
IUUC-Bra-017843	Brassica rapa	37.04	4.00e-29	122.00
IUUC-Cel-018199	Caenorhabditis elegans	43.63	2.00e-47	183.00
IUUC-Cja-019941	Callithrix jacchus	87.03	0.00e+00	740.00
IUUC-Cfa-020845	Canis familiaris	89.86	0.00e+00	768.00
IUUC-Cpo-022037	Cavia porcellus	87.26	0.00e+00	739.00
IUUC-Cre-022696	Chlamydomonas reinhardtii	33.71	3.00e-20	93.20
IUUC-Csa-023495	Chlorocebus sabaeus	86.79	0.00e+00	743.00
IUUC-Cho-025076	Choloepus hoffmanni	85.75	2.00e-178	619.00
IUUC-Cin-025400	Ciona intestinalis	39.21	6.00e-106	377.00
IUUC-Csv-025941	Ciona savignyi	41.12	1.00e-81	296.00
IUUC-Cgl-026725	Colletotrichum gloeosporioides	31.73	4.00e-26	113.00
IUUC-Cne-027057	Cryptococcus neoformans	30.10	3.00e-33	136.00
IUUC-Dre-028484	Danio rerio	60.85	0.00e+00	627.00
IUUC-Dno-028906	Dasypus novemcinctus	88.33	0.00e+00	748.00
IUUC-Dor-030124	Dipodomys ordii	93.55	5.00e-140	491.00
IUUC-Dse-031437	Dothistroma septosporum	26.11	2.00e-24	107.00
IUUC-Dme-031696	Drosophila melanogaster	41.22	5.00e-60	225.00
IUUC-Ete-032573	Echinops telfairi	84.02	0.00e+00	693.00
IUUC-Eca-033711	Equus caballus	88.92	0.00e+00	756.00
IUUC-Eeu-034459	Erinaceus europaeus	73.43	8.00e-79	288.00
IUUC-Fca-035447	Felis catus	81.05	0.00e+00	846.00
IUUC-Fal-036605	Ficedula albicollis	79.35	0.00e+00	649.00
IUUC-Fox-037967	Fusarium oxysporum	48.68	3.00e-17	84.00
IUUC-Fso-038110	Fusarium solani	32.54	4.00e-28	120.00
IUUC-Gmo-038785	Gadus morhua	58.29	0.00e+00	632.00
IUUC-Ggr-039760	Gaeumannomyces graminis	38.71	8.00e-27	115.00
IUUC-Gga-040584	Gallus gallus	83.25	0.00e+00	718.00
IUUC-Gac-042469	Gasterosteus aculeatus	56.00	2.00e-156	545.00
IUUC-Gma-044237	Glycine max	36.22	2.00e-26	113.00
IUUC-Ggo-044498	Gorilla gorilla	72.17	5.00e-174	603.00
IUUC-Hsa-046625	Homo sapiens	87.26	0.00e+00	741.00
IUUC-Hvu-047155	Hordeum vulgare	38.20	1.00e-26	114.00
IUUC-Itr-048753	Ictidomys tridecemlineatus	87.26	0.00e+00	740.00
IUUC-Kpa-049160	Komagataella pastoris	26.79	1.00e-22	101.00
IUUC-Lch-050529	Latimeria chalumnae	74.31	0.00e+00	851.00
IUUC-Lpe-051024	Leersia perrieri	35.16	4.00e-29	122.00
IUUC-Loc-052644	Lepisosteus oculatus	67.79	1.00e-158	553.00
IUUC-Lma-053102	Leptosphaeria maculans	36.00	2.00e-26	114.00
IUUC-Laf-054337	Loxodonta africana	85.14	0.00e+00	724.00
IUUC-Mcc-055659	Macaca mulatta	83.05	4.00e-137	481.00
IUUC-Meu-056084	Macropus eugenii	76.02	2.00e-93	336.00
IUUC-Mor-057255	Magnaporthe oryzae	37.42	6.00e-26	112.00
IUUC-Mpo-057454	Magnaporthe poae	38.71	2.00e-27	117.00
IUUC-Mtr-058098	Medicago truncatula	37.17	1.00e-29	124.00
IUUC-Mla-059068	Melampsora laricipopulina	34.85	1.00e-30	127.00
IUUC-Mga-059624	Meleagris gallopavo	72.93	0.00e+00	875.00
IUUC-Mvi-060282	Microbotryum violaceum	48.25	5.00e-21	97.10
IUUC-Mmr-061142	Microcebus murinus	87.50	0.00e+00	744.00
IUUC-Mdo-062289	Monodelphis domestica	78.42	0.00e+00	834.00
IUUC-Mmu-063961	Mus musculus	86.08	0.00e+00	733.00
IUUC-Mac-065188	Musa acuminata	36.31	9.00e-23	101.00
IUUC-Mpu-066291	Mustela putorius furo	89.15	0.00e+00	764.00
IUUC-Mlu-067431	Myotis lucifugus	83.25	0.00e+00	709.00
IUUC-Nfi-068422	Neosartorya fischeri	36.84	5.00e-28	119.00
IUUC-Ncr-068843	Neurospora crassa	38.27	1.00e-28	121.00
IUUC-Nle-069079	Nomascus leucogenys	87.03	0.00e+00	739.00
IUUC-Opr-070790	Ochotona princeps	84.00	6.00e-57	215.00
IUUC-Ont-071789	Oreochromis niloticus	59.53	2.00e-165	575.00
IUUC-Oan-072946	Ornithorhynchus anatinus	80.00	0.00e+00	684.00
IUUC-Ocu-073816	Oryctolagus cuniculus	87.97	0.00e+00	749.00
IUUC-Oba-075738	Oryza barthii	33.71	4.00e-18	85.90
IUUC-Obr-076355	Oryza brachyantha	38.33	1.00e-27	117.00
IUUC-Ogl-077592	Oryza glaberrima	34.39	7.00e-27	114.00
IUUC-Ogu-078197	Oryza glumaepatula	31.78	1.00e-26	114.00
IUUC-Oin-080047	Oryza indica	38.20	3.00e-26	112.00
IUUC-Olo-080317	Oryza longistaminata	34.39	2.00e-26	113.00
IUUC-Ome-081589	Oryza meridionalis	36.72	2.00e-26	114.00
IUUC-Oni-082700	Oryza nivara	33.71	3.00e-18	86.30
IUUC-Opu-083923	Oryza punctata	34.36	1.00e-21	96.70
IUUC-Oru-084318	Oryza rufipogon	33.71	3.00e-18	86.30
IUUC-Osa-086246	Oryza sativa	38.98	5.00e-07	45.40
IUUC-Ola-086730	Oryzias latipes	54.19	3.00e-148	518.00
IUUC-Olu-087719	Ostreococcus lucimarinus	34.46	9.00e-24	104.00
IUUC-Oga-088992	Otolemur garnettii	84.54	0.00e+00	1085.00
IUUC-Oar-089789	Ovis aries	88.00	0.00e+00	753.00
IUUC-Ptr-091636	Pan troglodytes	87.26	0.00e+00	741.00
IUUC-Pan-092911	Papio anubis	86.56	0.00e+00	737.00
IUUC-Psi-093194	Pelodiscus sinensis	81.09	0.00e+00	880.00
IUUC-Pma-094212	Petromyzon marinus	42.93	2.00e-102	365.00
IUUC-Pno-094831	Phaeosphaeria nodorum	33.33	7.00e-27	115.00
IUUC-Ppa-095705	Physcomitrella patens	34.39	2.00e-29	123.00
IUUC-Pfo-096694	Poecilia formosa	56.92	2.00e-167	582.00
IUUC-Pab-097706	Pongo abelii	87.03	0.00e+00	739.00
IUUC-Pop-099891	Populus trichocarpa	37.43	7.00e-26	112.00
IUUC-Pca-100879	Procavia capensis	79.37	3.00e-84	305.00
IUUC-Ppe-101334	Prunus persica	35.64	2.00e-26	113.00
IUUC-Pva-103225	Pteropus vampyrus	79.13	1.00e-166	579.00
IUUC-Pgr-103564	Puccinia graminis	34.41	8.00e-30	125.00
IUUC-Ptt-103802	Puccinia triticina	46.02	5.00e-25	109.00
IUUC-Pte-104345	Pyrenophora teres	34.16	2.00e-26	114.00
IUUC-Pyt-104716	Pyrenophora triticirepentis	34.30	3.00e-27	117.00
IUUC-Rno-106101	Rattus norvegicus	85.85	0.00e+00	734.00
IUUC-Sce-106460	Saccharomyces cerevisiae	33.33	9.00e-24	104.00
IUUC-Sha-106919	Sarcophilus harrisii	77.88	0.00e+00	926.00
IUUC-Sja-107880	Schizosaccharomyces japonicus	37.57	8.00e-30	125.00
IUUC-Spo-108087	Schizosaccharomyces pombe	34.78	1.00e-26	114.00
IUUC-Ssl-108614	Sclerotinia sclerotiorum	29.82	9.00e-08	52.40
IUUC-Smo-109411	Selaginella moellendorffii	36.67	3.00e-29	122.00
IUUC-Sit-110678	Setaria italica	37.64	1.00e-26	114.00
IUUC-Sly-111526	Solanum lycopersicum	37.50	5.00e-26	112.00
IUUC-Stu-112494	Solanum tuberosum	36.93	9.00e-27	114.00
IUUC-Sar-112929	Sorex araneus	97.82	2.00e-162	565.00
IUUC-Sbi-114242	Sorghum bicolor	35.53	2.00e-27	117.00
IUUC-Sre-115224	Sporisorium reilianum	36.51	8.00e-29	122.00
IUUC-Ssc-115239	Sus scrofa	88.92	0.00e+00	761.00
IUUC-Tgu-117499	Taeniopygia guttata	79.95	0.00e+00	686.00
IUUC-Tru-118027	Takifugu rubripes	56.53	3.00e-162	565.00
IUUC-Tsy-119462	Tarsius syrichta	87.50	0.00e+00	747.00
IUUC-Tni-120855	Tetraodon nigroviridis	52.24	1.00e-159	555.00
IUUC-Tca-121213	Theobroma cacao	35.45	3.00e-25	109.00
IUUC-Tre-122186	Trichoderma reesei	31.17	5.00e-27	115.00
IUUC-Tvi-122541	Trichoderma virens	38.73	3.00e-27	116.00
IUUC-Tae-122942	Triticum aestivum	39.33	4.00e-27	115.00
IUUC-Tur-126572	Triticum urartu	39.33	1.00e-26	114.00
IUUC-Tme-127023	Tuber melanosporum	35.90	4.00e-30	126.00
IUUC-Tbe-127453	Tupaia belangeri	88.68	0.00e+00	751.00
IUUC-Ttr-128526	Tursiops truncatus	88.21	0.00e+00	752.00
IUUC-Uma-129660	Ustilago maydis	36.51	9.00e-29	122.00
IUUC-Vda-129737	Verticillium dahliae	31.36	4.00e-23	103.00
IUUC-Vpa-130505	Vicugna pacos	82.55	0.00e+00	689.00
IUUC-Vvi-131088	Vitis vinifera	37.08	2.00e-24	107.00
IUUC-Xtr-132799	Xenopus tropicalis	71.39	6.00e-178	617.00
IUUC-Xma-133345	Xiphophorus maculatus	57.48	3.00e-163	568.00
IUUC-Yli-134416	Yarrowia lipolytica	29.74	5.00e-30	125.00
IUUC-Zma-134750	Zea mays	39.33	2.00e-26	113.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence