iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052891

Ensembl Protein ID

ENSLOCP00000015481.1

UniProt Accession

W5N4C2; W5N4C2_LEPOC

Genbank Protein ID

ENSLOCP00000015481

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

AHAT01002497

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000012568.1	ENSLOCT00000015510.1	ENSLOCP00000015481.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	5.30e-20	71.5	969	1018

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedek.slveCekCrewfHpaClklsveeelpnsekwiCpkC 51
           ++C vCg+ g++ +  l+ C++C +++Hp C+++++ + + ++  w C +C
   Q: 969  DMCVVCGSFGQGAEgRLLACSQCGQCYHPYCVSIKITRVVLSKG-WRCLEC 1018
           79*********9999********************777777775.****** PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MSSEDKTLEP SDQGPSPPPS STAATPAGSP ATTDKRPRGR PRKDGVAPTQ KSKKKSRSRG 60
KASVDDEDSM DGVETAEMEN PPSTEAKEPP AESDGVQSAE STGEEKPPSP VLQRSASEES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTATCCTG TGTATGAGTG CATTGCCATC GCCATAAGAG AAAGAAATGA AGATTTGTCT 60
GAAAATGATC TTTTTGCCAG TGCCTGGGTG GTGATCTCAA GTTGGAGTGC AAATTCCAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR009071--HMG_box_dom
IPR000637--HMGI/Y_DNA-bd_CS
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS00354--HMGI_Y
PS50868--POST_SET
PS50280--SET
PS50016--ZF_PHD_2
PS50089--ZF_RING_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET

SMART

SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00508--PostSET
SM00184--RING
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0006355--P:regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002314	Ailuropoda melanoleuca	50.47	0.00e+00	2573.00
IUUC-Apl-003311	Anas platyrhynchos	51.79	0.00e+00	2731.00
IUUC-Aca-004705	Anolis carolinensis	50.48	0.00e+00	2710.00
IUUC-Bta-012322	Bos taurus	52.51	0.00e+00	2076.00
IUUC-Bra-017422	Brassica rapa	35.05	5.00e-28	119.00
IUUC-Cja-019983	Callithrix jacchus	50.21	0.00e+00	2639.00
IUUC-Cfa-020903	Canis familiaris	50.62	0.00e+00	2647.00
IUUC-Cpo-021732	Cavia porcellus	49.96	0.00e+00	2528.00
IUUC-Csa-023083	Chlorocebus sabaeus	58.75	0.00e+00	3733.00
IUUC-Cho-024469	Choloepus hoffmanni	44.86	0.00e+00	959.00
IUUC-Dre-028110	Danio rerio	58.43	0.00e+00	2662.00
IUUC-Dor-030569	Dipodomys ordii	73.75	0.00e+00	1266.00
IUUC-Dme-031590	Drosophila melanogaster	32.58	2.00e-63	238.00
IUUC-Eca-033945	Equus caballus	54.33	0.00e+00	2091.00
IUUC-Fca-035922	Felis catus	49.79	0.00e+00	2512.00
IUUC-Gmo-039403	Gadus morhua	57.06	0.00e+00	1972.00
IUUC-Gac-041896	Gasterosteus aculeatus	55.09	0.00e+00	2704.00
IUUC-Ggo-044812	Gorilla gorilla	51.26	0.00e+00	2059.00
IUUC-Hsa-046595	Homo sapiens	52.80	0.00e+00	2182.00
IUUC-Itr-048303	Ictidomys tridecemlineatus	49.85	0.00e+00	2656.00
IUUC-Lch-050086	Latimeria chalumnae	52.22	0.00e+00	2298.00
IUUC-Laf-054348	Loxodonta africana	50.13	0.00e+00	1593.00
IUUC-Mcc-054868	Macaca mulatta	52.56	0.00e+00	2137.00
IUUC-Mga-059541	Meleagris gallopavo	52.22	0.00e+00	2823.00
IUUC-Mmr-061092	Microcebus murinus	56.17	0.00e+00	4254.00
IUUC-Mdo-062610	Monodelphis domestica	72.95	0.00e+00	1019.00
IUUC-Mmu-063666	Mus musculus	51.88	0.00e+00	2062.00
IUUC-Mac-064935	Musa acuminata	34.17	2.00e-28	120.00
IUUC-Mpu-066366	Mustela putorius furo	52.51	0.00e+00	2040.00
IUUC-Mlu-068201	Myotis lucifugus	51.06	0.00e+00	1655.00
IUUC-Nle-069232	Nomascus leucogenys	58.11	0.00e+00	3679.00
IUUC-Ont-072401	Oreochromis niloticus	59.89	0.00e+00	1467.00
IUUC-Oan-072945	Ornithorhynchus anatinus	59.22	0.00e+00	3732.00
IUUC-Ocu-074920	Oryctolagus cuniculus	56.02	0.00e+00	4241.00
IUUC-Ola-086436	Oryzias latipes	51.65	0.00e+00	2362.00
IUUC-Oga-088637	Otolemur garnettii	52.73	0.00e+00	2121.00
IUUC-Oar-089363	Ovis aries	51.55	0.00e+00	2033.00
IUUC-Ptr-091527	Pan troglodytes	52.74	0.00e+00	2181.00
IUUC-Pan-092102	Papio anubis	50.31	0.00e+00	2029.00
IUUC-Pma-094252	Petromyzon marinus	42.54	1.00e-126	448.00
IUUC-Pfo-096288	Poecilia formosa	55.23	0.00e+00	2338.00
IUUC-Pab-098241	Pongo abelii	74.98	0.00e+00	1459.00
IUUC-Pop-099620	Populus trichocarpa	31.53	2.00e-26	114.00
IUUC-Pca-100103	Procavia capensis	81.72	0.00e+00	1234.00
IUUC-Pva-102238	Pteropus vampyrus	70.99	0.00e+00	1358.00
IUUC-Sha-106550	Sarcophilus harrisii	50.32	0.00e+00	2213.00
IUUC-Sar-113183	Sorex araneus	75.38	3.00e-120	428.00
IUUC-Tgu-116677	Taeniopygia guttata	53.93	0.00e+00	1840.00
IUUC-Tru-118037	Takifugu rubripes	55.24	0.00e+00	1925.00
IUUC-Tsy-118932	Tarsius syrichta	76.07	0.00e+00	1503.00
IUUC-Tni-119970	Tetraodon nigroviridis	52.02	0.00e+00	2247.00
IUUC-Ttr-129051	Tursiops truncatus	51.73	0.00e+00	1965.00
IUUC-Vpa-130236	Vicugna pacos	68.02	0.00e+00	766.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence