iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107483

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01025438

Gene Name

BIRC6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000005067.1	ENSSHAT00000005861.1	ENSSHAP00000005807.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.00e-34	117.9	4473	4629

Active Site

Position(s)	Description	Evidence
4562	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    Rlkkelkelekdpp....egisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltk.....ifhPnvyen 78
           Rl++e+ +l+++ p    +++++++++e  l+ ++vli+Gp+dtpY++g+F+++++fp+dYP++PP v+++t+     +f+Pn+y++
   Q: 4473 RLAQEAVTLSTSLPlsssSSVFVRCDEE-RLDIMKVLITGPADTPYANGCFEFDVYFPQDYPSSPPLVNLETTgghsvRFNPNLYND 4558
           8999999999998877768899999999.6********************************************************* PP
   S: 79   GkvClsilk.....eeekWsp.alsvesvllsiqsll..aepnpesplneeaa...ellkknreeykkkvre 139
           GkvClsil+     +eekW+p ++s+ +vl+s+qsl+  aep++++p +e+++   + ++++re y+ ++r+
   Q: 4559 GKVCLSILNtwhgrPEEKWNPqTSSFLQVLVSVQSLIlvAEPYFNEPGYERSRgtpSGTQSSRE-YDGNIRQ 4629
           ********7788889******8899***********999***********99866555666655.9998875 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

TAKPGGRVKC QYISAVDKVI FVDDYAVGCR KDLNGILLLD TALQTPVSKQ DDVVQLELPV 60
TEAQQLLSAC IEKVDVSSSE GYDLFITQLK DGLKNTSHET AANHKVAKFY LIFLVTIHGV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAGCCAAAC CAGGTGGACG GGTGAAATGT CAGTATATAT CTGCTGTGGA TAAAGTTATC 60
TTTGTGGATG ATTATGCAGT AGGGTGTAGG AAAGACCTTA ATGGGATCTT ATTGCTAGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001370--BIR_rpt
IPR022103--BIRC6
IPR008979--Galactose-bd-like
IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD
IPR008883--UEV_N
IPR015943--WD40/YVTN_repeat-like_dom

PROSITE

PS50143--BIR_REPEAT_2
PS50127--UBIQUITIN_CONJUGAT_2
PS51322--UEV

Pfam

PF00653--BIR
PF12356--BIRC6
PF00179--UQ_con

SMART

SM00238--BIR

Gene Ontology

GO:0005768--C:endosome
GO:0016020--C:membrane
GO:0005815--C:microtubule organizing center
GO:0030496--C:midbody
GO:0000922--C:spindle pole
GO:0005802--C:trans-Golgi network
GO:0004869--F:cysteine-type endopeptidase inhibitor activity
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0006915--P:apoptotic process
GO:0060711--P:labyrinthine layer development
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0008284--P:positive regulation of cell proliferation
GO:0015031--P:protein transport
GO:0032465--P:regulation of cytokinesis
GO:0060712--P:spongiotrophoblast layer development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001583	Ailuropoda melanoleuca	91.10	0.00e+00	7977.00
IUUC-Atr-003108	Amborella trichopoda	42.86	4.00e-45	175.00
IUUC-Apl-004144	Anas platyrhynchos	93.29	0.00e+00	5672.00
IUUC-Aca-005257	Anolis carolinensis	88.12	0.00e+00	7712.00
IUUC-Ath-007217	Arabidopsis thaliana	37.17	1.00e-44	174.00
IUUC-Ame-011337	Astyanax mexicanus	76.03	0.00e+00	6310.00
IUUC-Bta-012501	Bos taurus	90.04	0.00e+00	7805.00
IUUC-Bdi-014931	Brachypodium distachyon	38.52	2.00e-46	179.00
IUUC-Bol-015976	Brassica oleracea	39.92	9.00e-46	177.00
IUUC-Bra-017967	Brassica rapa	39.92	4.00e-46	178.00
IUUC-Cel-018661	Caenorhabditis elegans	36.44	2.00e-79	290.00
IUUC-Cja-018746	Callithrix jacchus	90.88	0.00e+00	7901.00
IUUC-Cfa-020170	Canis familiaris	91.08	0.00e+00	7934.00
IUUC-Cpo-022138	Cavia porcellus	92.67	0.00e+00	5569.00
IUUC-Cre-022768	Chlamydomonas reinhardtii	44.69	1.00e-44	172.00
IUUC-Csa-023927	Chlorocebus sabaeus	90.67	0.00e+00	7869.00
IUUC-Cho-024890	Choloepus hoffmanni	90.40	0.00e+00	1860.00
IUUC-Cne-026995	Cryptococcus neoformans	42.62	2.00e-37	151.00
IUUC-Dre-027941	Danio rerio	77.58	0.00e+00	6660.00
IUUC-Dno-028913	Dasypus novemcinctus	89.55	0.00e+00	7805.00
IUUC-Dor-030715	Dipodomys ordii	91.12	0.00e+00	1874.00
IUUC-Dse-031232	Dothistroma septosporum	44.51	4.00e-38	153.00
IUUC-Dme-031592	Drosophila melanogaster	52.78	0.00e+00	674.00
IUUC-Ete-032587	Echinops telfairi	74.35	0.00e+00	1970.00
IUUC-Eca-033819	Equus caballus	90.90	0.00e+00	7891.00
IUUC-Eeu-034863	Erinaceus europaeus	82.27	0.00e+00	2430.00
IUUC-Fca-035505	Felis catus	89.42	0.00e+00	7700.00
IUUC-Fal-037318	Ficedula albicollis	90.73	0.00e+00	7908.00
IUUC-Gmo-039521	Gadus morhua	81.88	0.00e+00	1679.00
IUUC-Ggr-040040	Gaeumannomyces graminis	47.06	2.00e-33	138.00
IUUC-Gga-040728	Gallus gallus	90.61	0.00e+00	7822.00
IUUC-Gac-042251	Gasterosteus aculeatus	84.92	0.00e+00	1806.00
IUUC-Ggo-045562	Gorilla gorilla	92.67	0.00e+00	1528.00
IUUC-Hsa-046339	Homo sapiens	90.93	0.00e+00	7823.00
IUUC-Hvu-047441	Hordeum vulgare	46.70	3.00e-47	182.00
IUUC-Itr-048099	Ictidomys tridecemlineatus	92.47	0.00e+00	2570.00
IUUC-Lch-050164	Latimeria chalumnae	84.21	0.00e+00	7180.00
IUUC-Lpe-051294	Leersia perrieri	40.23	3.00e-47	182.00
IUUC-Loc-052800	Lepisosteus oculatus	83.29	0.00e+00	7183.00
IUUC-Laf-054034	Loxodonta africana	90.24	0.00e+00	7853.00
IUUC-Mcc-055267	Macaca mulatta	90.78	0.00e+00	7859.00
IUUC-Meu-056461	Macropus eugenii	97.30	0.00e+00	1296.00
IUUC-Mpo-057396	Magnaporthe poae	49.03	1.00e-34	141.00
IUUC-Mtr-057797	Medicago truncatula	39.52	3.00e-47	182.00
IUUC-Mla-059114	Melampsora laricipopulina	27.82	4.00e-42	166.00
IUUC-Mga-059594	Meleagris gallopavo	90.35	0.00e+00	7513.00
IUUC-Mmr-061179	Microcebus murinus	90.70	0.00e+00	7826.00
IUUC-Mdo-062990	Monodelphis domestica	95.56	0.00e+00	8082.00
IUUC-Mmu-063825	Mus musculus	88.58	0.00e+00	7678.00
IUUC-Mac-064881	Musa acuminata	43.41	5.00e-42	165.00
IUUC-Mpu-065908	Mustela putorius furo	92.95	0.00e+00	5313.00
IUUC-Mlu-067106	Myotis lucifugus	89.55	0.00e+00	7812.00
IUUC-Nle-069347	Nomascus leucogenys	91.03	0.00e+00	7879.00
IUUC-Opr-070799	Ochotona princeps	83.30	0.00e+00	2430.00
IUUC-Ont-072046	Oreochromis niloticus	77.79	0.00e+00	6537.00
IUUC-Oan-073415	Ornithorhynchus anatinus	90.59	0.00e+00	3253.00
IUUC-Ocu-074556	Oryctolagus cuniculus	90.41	0.00e+00	7817.00
IUUC-Oba-075870	Oryza barthii	39.31	1.00e-47	183.00
IUUC-Obr-076463	Oryza brachyantha	40.00	8.00e-47	180.00
IUUC-Ogl-077040	Oryza glaberrima	39.55	6.00e-40	158.00
IUUC-Ogu-077966	Oryza glumaepatula	39.31	1.00e-47	183.00
IUUC-Oin-079561	Oryza indica	39.55	5.00e-40	158.00
IUUC-Olo-080416	Oryza longistaminata	39.93	1.00e-40	162.00
IUUC-Ome-081384	Oryza meridionalis	39.55	7.00e-40	158.00
IUUC-Oni-082326	Oryza nivara	39.46	2.00e-47	182.00
IUUC-Opu-083659	Oryza punctata	38.04	2.00e-46	179.00
IUUC-Oru-084622	Oryza rufipogon	39.55	6.00e-40	158.00
IUUC-Osa-085920	Oryza sativa	39.55	6.00e-40	158.00
IUUC-Ola-087459	Oryzias latipes	83.47	0.00e+00	2930.00
IUUC-Oga-088251	Otolemur garnettii	88.77	0.00e+00	7479.00
IUUC-Oar-090367	Ovis aries	90.31	0.00e+00	7819.00
IUUC-Ptr-091512	Pan troglodytes	90.95	0.00e+00	7862.00
IUUC-Pan-092222	Papio anubis	90.45	0.00e+00	7834.00
IUUC-Pma-094574	Petromyzon marinus	60.67	0.00e+00	2990.00
IUUC-Ppa-095592	Physcomitrella patens	29.81	6.00e-55	209.00
IUUC-Pfo-097086	Poecilia formosa	75.96	0.00e+00	6492.00
IUUC-Pab-098390	Pongo abelii	93.35	0.00e+00	5868.00
IUUC-Pop-099284	Populus trichocarpa	37.75	3.00e-42	166.00
IUUC-Pca-101036	Procavia capensis	84.47	0.00e+00	3917.00
IUUC-Pva-103053	Pteropus vampyrus	83.51	0.00e+00	3074.00
IUUC-Pte-104333	Pyrenophora teres	41.29	7.00e-44	173.00
IUUC-Pyt-104498	Pyrenophora triticirepentis	39.39	3.00e-44	173.00
IUUC-Rno-106049	Rattus norvegicus	88.54	0.00e+00	6213.00
IUUC-Smo-108915	Selaginella moellendorffii	42.96	9.00e-45	173.00
IUUC-Sly-110929	Solanum lycopersicum	37.98	2.00e-46	180.00
IUUC-Stu-112554	Solanum tuberosum	38.76	1.00e-46	181.00
IUUC-Sar-112965	Sorex araneus	72.26	0.00e+00	1437.00
IUUC-Sbi-114743	Sorghum bicolor	38.91	4.00e-44	172.00
IUUC-Ssc-115927	Sus scrofa	93.06	0.00e+00	5713.00
IUUC-Tgu-117132	Taeniopygia guttata	90.38	0.00e+00	7844.00
IUUC-Tru-118115	Takifugu rubripes	74.43	0.00e+00	6321.00
IUUC-Tsy-118899	Tarsius syrichta	89.85	0.00e+00	4772.00
IUUC-Tni-120891	Tetraodon nigroviridis	72.89	0.00e+00	6274.00
IUUC-Tae-125407	Triticum aestivum	47.25	2.00e-47	183.00
IUUC-Tur-126479	Triticum urartu	46.41	2.00e-43	170.00
IUUC-Tme-126930	Tuber melanosporum	42.60	5.00e-48	186.00
IUUC-Tbe-127630	Tupaia belangeri	87.13	0.00e+00	1389.00
IUUC-Ttr-128629	Tursiops truncatus	88.58	0.00e+00	7669.00
IUUC-Vpa-130310	Vicugna pacos	89.90	0.00e+00	7699.00
IUUC-Xtr-131861	Xenopus tropicalis	82.20	0.00e+00	6943.00
IUUC-Xma-133613	Xiphophorus maculatus	76.13	0.00e+00	6447.00
IUUC-Zma-135768	Zea mays	35.90	8.00e-45	176.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence