iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001968

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01122438

Gene Name

RNF149

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000015580.1	ENSAMET00000017108.1	ENSAMEP00000016429.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.80e-06	27.8	241	282

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C e f  kd  ++lpC+H+fh+ C+  w         + +CP C+
   Q: 241  CAVCIENFkvKDIIRILPCKHIFHRICIDPW------LLDHRTCPMCK 282
           ********8866699****************......9999******6 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

GARGRAFEWY SAVVSTEYVD PYTNRTVWSV SESGRFGDSS PKEGAQGLVG VPRAADRDPE 60
GCAPDTRFLV PAPGGRGDAP WVALVARGGC TFKDKVLVAA RRNASAVVLY NEEGHGNLTT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGCCAGGG GCCGGGCGTT CGAGTGGTAC TCGGCCGTGG TGAGCACCGA GTACGTGGAC 60
CCGTACACGA ACCGCACCGT GTGGAGCGTC TCAGAGAGCG GCCGCTTCGG CGACAGCTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0035690--P:cellular response to drug
GO:0043409--P:negative regulation of MAPK cascade
GO:0031647--P:regulation of protein stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004109	Anas platyrhynchos	73.38	2.00e-99	354.00
IUUC-Bta-012340	Bos taurus	82.92	2.00e-171	595.00
IUUC-Cja-019566	Callithrix jacchus	83.29	1.00e-175	608.00
IUUC-Cfa-020289	Canis familiaris	94.54	8.00e-125	439.00
IUUC-Cpo-021916	Cavia porcellus	67.80	4.00e-77	280.00
IUUC-Csa-024084	Chlorocebus sabaeus	84.66	1.00e-173	602.00
IUUC-Cho-024305	Choloepus hoffmanni	80.00	4.00e-132	463.00
IUUC-Cgl-026578	Colletotrichum gloeosporioides	48.08	2.00e-12	67.00
IUUC-Cne-026985	Cryptococcus neoformans	28.97	7.00e-11	63.20
IUUC-Dno-030098	Dasypus novemcinctus	83.78	2.00e-180	625.00
IUUC-Dor-030620	Dipodomys ordii	75.98	3.00e-140	491.00
IUUC-Ete-032306	Echinops telfairi	85.75	2.00e-175	607.00
IUUC-Fca-035950	Felis catus	91.46	6.00e-127	446.00
IUUC-Fal-037429	Ficedula albicollis	70.38	2.00e-137	481.00
IUUC-Fox-038011	Fusarium oxysporum	38.81	4.00e-13	69.70
IUUC-Fso-038141	Fusarium solani	41.77	7.00e-16	78.60
IUUC-Gga-041201	Gallus gallus	68.50	8.00e-133	466.00
IUUC-Ggo-045429	Gorilla gorilla	83.89	2.00e-168	585.00
IUUC-Hsa-046191	Homo sapiens	83.06	7.00e-173	599.00
IUUC-Itr-048018	Ictidomys tridecemlineatus	78.98	9.00e-156	542.00
IUUC-Lch-049498	Latimeria chalumnae	62.30	5.00e-133	467.00
IUUC-Laf-054239	Loxodonta africana	74.64	5.00e-131	460.00
IUUC-Meu-056382	Macropus eugenii	76.26	9.00e-153	532.00
IUUC-Mla-058935	Melampsora laricipopulina	39.02	2.00e-09	57.80
IUUC-Mga-059435	Meleagris gallopavo	70.37	6.00e-65	239.00
IUUC-Mmr-061513	Microcebus murinus	81.64	1.00e-170	592.00
IUUC-Mdo-063028	Monodelphis domestica	77.22	1.00e-156	545.00
IUUC-Mmu-063545	Mus musculus	77.99	2.00e-152	531.00
IUUC-Mpu-066370	Mustela putorius furo	94.85	0.00e+00	676.00
IUUC-Mlu-067271	Myotis lucifugus	81.76	2.00e-139	488.00
IUUC-Nle-069207	Nomascus leucogenys	84.14	2.00e-175	608.00
IUUC-Opr-070704	Ochotona princeps	72.47	3.00e-95	340.00
IUUC-Oan-072837	Ornithorhynchus anatinus	68.09	2.00e-141	495.00
IUUC-Ocu-074671	Oryctolagus cuniculus	80.07	6.00e-125	439.00
IUUC-Oga-089083	Otolemur garnettii	83.56	2.00e-174	605.00
IUUC-Oar-089254	Ovis aries	81.63	1.00e-112	398.00
IUUC-Ptr-090940	Pan troglodytes	83.78	1.00e-173	602.00
IUUC-Pan-092636	Papio anubis	85.48	2.00e-175	608.00
IUUC-Psi-093435	Pelodiscus sinensis	74.89	8.00e-93	332.00
IUUC-Pab-098525	Pongo abelii	85.24	8.00e-172	596.00
IUUC-Pva-102395	Pteropus vampyrus	84.11	2.00e-179	621.00
IUUC-Pgr-103263	Puccinia graminis	38.18	3.00e-11	63.90
IUUC-Rno-105789	Rattus norvegicus	78.12	2.00e-151	528.00
IUUC-Sha-107305	Sarcophilus harrisii	75.11	7.00e-95	339.00
IUUC-Ssc-115598	Sus scrofa	84.37	1.00e-173	602.00
IUUC-Tgu-116463	Taeniopygia guttata	69.38	2.00e-130	458.00
IUUC-Tsy-118915	Tarsius syrichta	79.27	8.00e-105	372.00
IUUC-Tre-121978	Trichoderma reesei	48.98	1.00e-12	67.80
IUUC-Tme-126970	Tuber melanosporum	49.06	7.00e-13	68.90
IUUC-Tbe-127906	Tupaia belangeri	66.94	6.00e-82	296.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence