iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020591

Ensembl Protein ID

ENSCAFP00000016653.3

UniProt Accession

F1Q1Q0; F1Q1Q0_CANLF

Genbank Protein ID

ENSCAFP00000016653

Protein Name

Coronin

Genbank Nucleotide ID

AAEX03014753

Gene Name

CORO1C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000011301.4	ENSCAFT00000017981.3	ENSCAFP00000016653.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-15	57.1	129	161

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHt++v ++++   +d  ++sGs D+t++vW +
   Q: 129  GHTGPVLDIDWcphNDQVIASGSEDCTVMVWQI 161
           8***********977799*************86 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

IYGPGSQLER SGNSWAEEHG CSAACQAFVA SAQPHAPLGK RPLLHMPWKD TMRRVVRQSK 60
FRHVFGQAVK NDQCYDDIRV SRVTWDSSFC AVNPRFVAII IEASGGGAFL VLPLHKTGRI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCCCGGGGG CGCCCGGAGG CGTGGCCCTG GGGGTGGACT CGTGGGCGGC GCGTGGGCTC 60
GGCTGCCGCC TCCCTCCGCA GCCCACTCGC TCCCCCCGGC GCGACCAGAG GGGGCGCTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR027333--CORO1C
IPR015505--Coronin
IPR015048--DUF1899
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0016600--C:flotillin complex
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0016328--C:lateral plasma membrane
GO:0031982--C:vesicle
GO:0051015--F:actin filament binding
GO:0030036--P:actin cytoskeleton organization
GO:0090630--P:activation of GTPase activity
GO:0045184--P:establishment of protein localization
GO:0010633--P:negative regulation of epithelial cell migration
GO:0051895--P:negative regulation of focal adhesion assembly
GO:0044387--P:negative regulation of protein kinase activity by regulation of protein phosphorylation
GO:1900025--P:negative regulation of substrate adhesion-dependent cell spreading
GO:0001755--P:neural crest cell migration
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:0010762--P:regulation of fibroblast migration
GO:1900027--P:regulation of ruffle assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002236	Ailuropoda melanoleuca	99.58	0.00e+00	989.00
IUUC-Apl-003861	Anas platyrhynchos	94.74	0.00e+00	949.00
IUUC-Acl-008280	Aspergillus clavatus	43.81	5.00e-98	352.00
IUUC-Afl-008393	Aspergillus flavus	44.06	1.00e-97	350.00
IUUC-Afu-008865	Aspergillus fumigatus	42.07	7.00e-94	338.00
IUUC-Ani-009155	Aspergillus nidulans	43.56	3.00e-99	355.00
IUUC-Ang-009523	Aspergillus niger	41.60	3.00e-88	319.00
IUUC-Aor-010049	Aspergillus oryzae	43.58	2.00e-94	340.00
IUUC-Ate-010368	Aspergillus terreus	43.36	3.00e-94	339.00
IUUC-Ame-011256	Astyanax mexicanus	80.21	0.00e+00	788.00
IUUC-Bta-013225	Bos taurus	95.04	0.00e+00	993.00
IUUC-Bci-013935	Botrytis cinerea	43.28	5.00e-100	358.00
IUUC-Cja-019948	Callithrix jacchus	95.45	0.00e+00	1041.00
IUUC-Cpo-021480	Cavia porcellus	98.52	0.00e+00	977.00
IUUC-Csa-024152	Chlorocebus sabaeus	99.16	0.00e+00	988.00
IUUC-Cho-024687	Choloepus hoffmanni	98.16	0.00e+00	900.00
IUUC-Csv-026184	Ciona savignyi	42.21	3.00e-87	315.00
IUUC-Cgl-026456	Colletotrichum gloeosporioides	43.18	2.00e-96	346.00
IUUC-Dre-028541	Danio rerio	83.33	0.00e+00	789.00
IUUC-Dno-029552	Dasypus novemcinctus	98.62	0.00e+00	899.00
IUUC-Dse-031378	Dothistroma septosporum	42.46	2.00e-91	330.00
IUUC-Dme-032091	Drosophila melanogaster	53.47	2.00e-153	535.00
IUUC-Ete-032839	Echinops telfairi	89.45	0.00e+00	875.00
IUUC-Eca-034118	Equus caballus	98.53	0.00e+00	980.00
IUUC-Fca-035549	Felis catus	99.58	0.00e+00	984.00
IUUC-Fal-037065	Ficedula albicollis	88.76	0.00e+00	956.00
IUUC-Fox-037737	Fusarium oxysporum	43.28	2.00e-93	336.00
IUUC-Fso-038184	Fusarium solani	43.41	9.00e-99	354.00
IUUC-Gmo-038678	Gadus morhua	77.59	0.00e+00	781.00
IUUC-Ggr-039956	Gaeumannomyces graminis	42.64	2.00e-96	346.00
IUUC-Gga-040842	Gallus gallus	94.95	0.00e+00	956.00
IUUC-Gac-041543	Gasterosteus aculeatus	78.45	0.00e+00	772.00
IUUC-Ggo-044477	Gorilla gorilla	96.39	0.00e+00	1054.00
IUUC-Hsa-046610	Homo sapiens	96.02	0.00e+00	1050.00
IUUC-Itr-048583	Ictidomys tridecemlineatus	93.36	0.00e+00	1018.00
IUUC-Lch-050453	Latimeria chalumnae	84.34	0.00e+00	835.00
IUUC-Loc-052911	Lepisosteus oculatus	84.58	0.00e+00	840.00
IUUC-Lma-053160	Leptosphaeria maculans	43.28	2.00e-99	356.00
IUUC-Laf-053416	Loxodonta africana	98.31	0.00e+00	976.00
IUUC-Mcc-055113	Macaca mulatta	99.16	0.00e+00	984.00
IUUC-Meu-056732	Macropus eugenii	82.11	0.00e+00	755.00
IUUC-Mor-056978	Magnaporthe oryzae	39.62	2.00e-99	356.00
IUUC-Mpo-057410	Magnaporthe poae	43.14	3.00e-90	325.00
IUUC-Mga-060143	Meleagris gallopavo	94.93	0.00e+00	949.00
IUUC-Mmr-061130	Microcebus murinus	95.24	0.00e+00	1037.00
IUUC-Mdo-062851	Monodelphis domestica	87.18	0.00e+00	813.00
IUUC-Mmu-063663	Mus musculus	97.26	0.00e+00	962.00
IUUC-Mpu-066179	Mustela putorius furo	99.37	0.00e+00	983.00
IUUC-Mlu-068175	Myotis lucifugus	97.92	0.00e+00	982.00
IUUC-Nfi-068476	Neosartorya fischeri	42.82	2.00e-96	346.00
IUUC-Ncr-068781	Neurospora crassa	42.89	7.00e-98	351.00
IUUC-Nle-070001	Nomascus leucogenys	95.57	0.00e+00	808.00
IUUC-Opr-070617	Ochotona princeps	97.89	0.00e+00	936.00
IUUC-Ont-072629	Oreochromis niloticus	83.09	0.00e+00	842.00
IUUC-Oan-073547	Ornithorhynchus anatinus	95.76	0.00e+00	953.00
IUUC-Ocu-074569	Oryctolagus cuniculus	94.67	0.00e+00	1042.00
IUUC-Ola-086558	Oryzias latipes	80.25	0.00e+00	828.00
IUUC-Oga-089145	Otolemur garnettii	98.95	0.00e+00	981.00
IUUC-Oar-089654	Ovis aries	95.23	0.00e+00	1002.00
IUUC-Ptr-090763	Pan troglodytes	99.37	0.00e+00	983.00
IUUC-Pan-091885	Papio anubis	99.13	0.00e+00	942.00
IUUC-Psi-093011	Pelodiscus sinensis	93.89	0.00e+00	941.00
IUUC-Pno-094994	Phaeosphaeria nodorum	44.14	9.00e-98	351.00
IUUC-Pfo-097309	Poecilia formosa	82.66	0.00e+00	845.00
IUUC-Pab-097542	Pongo abelii	90.72	0.00e+00	876.00
IUUC-Pca-100630	Procavia capensis	84.38	0.00e+00	788.00
IUUC-Ptt-103735	Puccinia triticina	35.03	7.00e-70	258.00
IUUC-Pte-104194	Pyrenophora teres	42.64	2.00e-98	352.00
IUUC-Pyt-104437	Pyrenophora triticirepentis	42.64	3.00e-98	352.00
IUUC-Rno-105330	Rattus norvegicus	98.10	0.00e+00	972.00
IUUC-Sha-106695	Sarcophilus harrisii	94.63	0.00e+00	773.00
IUUC-Sja-107992	Schizosaccharomyces japonicus	41.96	5.00e-98	352.00
IUUC-Spo-108364	Schizosaccharomyces pombe	43.47	7.00e-98	351.00
IUUC-Ssc-115348	Sus scrofa	94.68	0.00e+00	1031.00
IUUC-Tgu-116597	Taeniopygia guttata	94.74	0.00e+00	949.00
IUUC-Tru-118425	Takifugu rubripes	80.84	0.00e+00	822.00
IUUC-Tsy-119223	Tarsius syrichta	88.28	0.00e+00	766.00
IUUC-Tni-120610	Tetraodon nigroviridis	80.55	0.00e+00	817.00
IUUC-Tre-122159	Trichoderma reesei	41.50	8.00e-94	337.00
IUUC-Tvi-122480	Trichoderma virens	42.00	3.00e-95	342.00
IUUC-Tbe-127679	Tupaia belangeri	88.14	0.00e+00	642.00
IUUC-Ttr-129226	Tursiops truncatus	88.82	0.00e+00	843.00
IUUC-Vda-129792	Verticillium dahliae	42.14	4.00e-94	338.00
IUUC-Vpa-130339	Vicugna pacos	99.40	0.00e+00	702.00
IUUC-Xtr-132873	Xenopus tropicalis	75.16	0.00e+00	749.00
IUUC-Xma-134047	Xiphophorus maculatus	82.91	0.00e+00	848.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence