iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ani-009391

Ensembl Protein ID

CADANIAP00006850

UniProt Accession

Q5AZX0; C8V295; PFS2_EMENI

Genbank Protein ID

EAA57946.1; CBF70064.1

Protein Name

Polyadenylation factor subunit 2

Genbank Nucleotide ID

AACD01000105; BN001301

Gene Name

ANIA_06160; pfs2; AN6160

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADANIAG00006850	CADANIAT00006850	CADANIAP00006850

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.40e-31	104.4	199	232
UBD/Beta-Prp	3.70e-45	153.5	91	380

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 5    svtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           +v ++++ ++ +llvsGs D+++k WD+rt ++l
   Q: 199  DVKSCDWhPTkGLLVSGSKDHQVKFWDPRTARCL 232
           5999****989********************997 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..................lrsl.sgheaevtavkfspdgkilvtgseDrtikvwd 80
           g+ k++it+v ++p+++ l+tg+ +g   +w+ t  ++                  ++++   h ++v+++ +sp++  ++++s+D t+k++d
   Q: 91   GKSKKPITVVRWTPEGRRLLTGGHTGEFMLWNGTAFNFetvmdkgdvkywrpnfnnVETIdDAHHDAVRDLAWSPSDTKFLSASDDTTLKIYD 183
           67799******************************999******************9999999****************************** PP
   S: 81   lstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkll 172
           + +++c  +l+gh+ +v s++++p++  lvsGs+d  ++ wd +t  cl  tl  h+ +v+ ++++  + nll+++s D+t r++dl++++ +
   Q: 184  FTARTCDTVLTGHNWDVKSCDWHPTKGLLVSGSKDHQVKFWDPRTARCLT-TLHSHKNTVTATKFSRVNnNLLATSSRDQTARVFDLRMMRDI 275
           *************************************************9.*****************99*********************** PP
   S: 173  rtltgghtdsvyslsfdsng.kelvsgsldgtvklwdlqtgec...........................vrtlnghtdnvksvrfspnderl 237
             l+g h++++  l++++     + +gs+dg++  + l + +                             r++ +h ++++ ++ +p +++l
   Q: 276  CILRG-HEKPISTLTWHPVHcSLISTGSEDGSLYHYLLDEPNLpagqiptvapydspdpantpaqviypaHRIQYAHAATIWTLDWHPLGHIL 367
           ****9.************99667778*************665566666888999999999999999999999999999*************** PP
   S: 238  vsgssDgsiriWd 250
           +sgs+D+  r+W 
   Q: 368  ASGSKDNFTRFWS 380
           ************4 PP

Organism

Aspergillus nidulans

Functional Description
(View)

Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle (By similarity).

Protein Sequence
(Fasta)

MAYYDDGGND SQPFGRAQGG IQGPRRPRLV TDYGSSMVQW MRNRRPKYQG GHRMETERPS 60
ASYMVDMLPP LARIHSPVDS IPVRHLHQSI GKSKKPITVV RWTPEGRRLL TGGHTGEFML 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTAGCTACAT TTGACGACGT TGCTATTCGA AATTAATCTT GGCTGCCAAA GCTGACTAGA 60
CCGACCTCGC CTTATCAGTG CGTCCGTGAC CCGTCGGCCC GTCAAGCTCT CCGCCTCCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0159--Chromosome partition
KW-0181--Complete proteome
KW-0507--mRNA processing
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005847--C:mRNA cleavage and polyadenylation specificity factor complex
GO:0000790--C:nuclear chromatin
GO:0007059--P:chromosome segregation
GO:0031124--P:mRNA 3'-end processing
GO:0006379--P:mRNA cleavage

KEGG

ani:AN6160.2

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001064	Aegilops tauschii	37.32	2.00e-77	281.00
IUUC-Aml-001363	Ailuropoda melanoleuca	39.90	3.00e-84	305.00
IUUC-Atr-003030	Amborella trichopoda	39.53	4.00e-82	297.00
IUUC-Apl-003409	Anas platyrhynchos	39.70	1.00e-82	300.00
IUUC-Aca-004694	Anolis carolinensis	39.65	1.00e-83	303.00
IUUC-Aly-006063	Arabidopsis lyrata	40.21	1.00e-81	295.00
IUUC-Ath-006583	Arabidopsis thaliana	40.27	9.00e-81	292.00
IUUC-Ago-007805	Ashbya gossypii	39.84	8.00e-76	275.00
IUUC-Acl-008075	Aspergillus clavatus	83.73	0.00e+00	816.00
IUUC-Afl-008582	Aspergillus flavus	75.52	0.00e+00	780.00
IUUC-Afu-008817	Aspergillus fumigatus	76.45	0.00e+00	719.00
IUUC-Ang-009750	Aspergillus niger	84.02	8.00e-170	587.00
IUUC-Aor-010085	Aspergillus oryzae	75.80	0.00e+00	849.00
IUUC-Ate-010397	Aspergillus terreus	72.16	0.00e+00	825.00
IUUC-Ame-010741	Astyanax mexicanus	42.31	1.00e-49	190.00
IUUC-Bgr-012169	Blumeria graminis	63.66	3.00e-138	483.00
IUUC-Bta-013265	Bos taurus	39.90	5.00e-84	305.00
IUUC-Bci-013762	Botrytis cinerea	62.61	2.00e-162	563.00
IUUC-Bdi-014849	Brachypodium distachyon	38.54	2.00e-83	301.00
IUUC-Bol-015325	Brassica oleracea	38.81	2.00e-83	301.00
IUUC-Bra-017064	Brassica rapa	39.90	1.00e-84	305.00
IUUC-Cel-018378	Caenorhabditis elegans	38.18	3.00e-78	284.00
IUUC-Cja-019547	Callithrix jacchus	39.90	3.00e-84	305.00
IUUC-Cfa-020031	Canis familiaris	39.90	4.00e-84	305.00
IUUC-Cpo-021554	Cavia porcellus	39.85	8.00e-84	303.00
IUUC-Cre-022830	Chlamydomonas reinhardtii	33.07	2.00e-47	181.00
IUUC-Csa-023146	Chlorocebus sabaeus	39.65	1.00e-83	303.00
IUUC-Cho-024679	Choloepus hoffmanni	39.61	3.00e-75	275.00
IUUC-Cin-025415	Ciona intestinalis	35.70	8.00e-72	263.00
IUUC-Csv-026003	Ciona savignyi	35.19	8.00e-70	256.00
IUUC-Cgl-026391	Colletotrichum gloeosporioides	64.10	1.00e-149	521.00
IUUC-Cne-026983	Cryptococcus neoformans	38.31	6.00e-74	270.00
IUUC-Cme-027147	Cyanidioschyzon merolae	38.92	3.00e-77	280.00
IUUC-Dre-028545	Danio rerio	39.39	6.00e-82	297.00
IUUC-Dno-029677	Dasypus novemcinctus	39.90	1.00e-84	306.00
IUUC-Dse-031371	Dothistroma septosporum	52.97	1.00e-123	434.00
IUUC-Dme-031663	Drosophila melanogaster	37.86	4.00e-79	287.00
IUUC-Ete-032511	Echinops telfairi	32.58	1.00e-59	223.00
IUUC-Eca-034152	Equus caballus	39.90	3.00e-84	305.00
IUUC-Fca-035820	Felis catus	39.90	4.00e-84	305.00
IUUC-Fox-037958	Fusarium oxysporum	62.59	5.00e-155	539.00
IUUC-Fso-038162	Fusarium solani	63.03	2.00e-154	537.00
IUUC-Gmo-039708	Gadus morhua	38.85	2.00e-82	298.00
IUUC-Ggr-040031	Gaeumannomyces graminis	61.12	6.00e-148	515.00
IUUC-Gga-040963	Gallus gallus	39.90	3.00e-84	305.00
IUUC-Gac-041541	Gasterosteus aculeatus	38.65	4.00e-79	288.00
IUUC-Gma-044352	Glycine max	39.18	6.00e-86	310.00
IUUC-Ggo-045564	Gorilla gorilla	39.90	3.00e-84	305.00
IUUC-Hsa-045833	Homo sapiens	39.90	3.00e-84	305.00
IUUC-Hvu-047848	Hordeum vulgare	39.64	2.00e-61	228.00
IUUC-Itr-048083	Ictidomys tridecemlineatus	39.90	5.00e-84	305.00
IUUC-Kpa-049308	Komagataella pastoris	41.28	3.00e-91	327.00
IUUC-Lch-050525	Latimeria chalumnae	40.40	3.00e-84	305.00
IUUC-Lpe-051364	Leersia perrieri	33.66	3.00e-65	241.00
IUUC-Loc-052696	Lepisosteus oculatus	39.14	5.00e-83	301.00
IUUC-Lma-052951	Leptosphaeria maculans	60.64	3.00e-140	490.00
IUUC-Laf-053653	Loxodonta africana	39.90	8.00e-84	303.00
IUUC-Mcc-055797	Macaca mulatta	39.90	3.00e-84	305.00
IUUC-Meu-056331	Macropus eugenii	44.07	4.00e-66	244.00
IUUC-Mor-057168	Magnaporthe oryzae	61.29	2.00e-151	527.00
IUUC-Mpo-057510	Magnaporthe poae	55.97	6.00e-87	312.00
IUUC-Mtr-058032	Medicago truncatula	39.09	7.00e-83	300.00
IUUC-Mla-058852	Melampsora laricipopulina	40.54	3.00e-90	323.00
IUUC-Mga-059311	Meleagris gallopavo	39.90	4.00e-84	305.00
IUUC-Mvi-060544	Microbotryum violaceum	41.51	2.00e-85	307.00
IUUC-Mmr-061143	Microcebus murinus	39.90	4.00e-84	305.00
IUUC-Mdo-061977	Monodelphis domestica	39.90	3.00e-84	305.00
IUUC-Mmu-063922	Mus musculus	39.90	3.00e-84	305.00
IUUC-Mac-064961	Musa acuminata	38.83	6.00e-83	300.00
IUUC-Mpu-066079	Mustela putorius furo	40.97	3.00e-77	282.00
IUUC-Mlu-067247	Myotis lucifugus	39.90	2.00e-84	305.00
IUUC-Nfi-068255	Neosartorya fischeri	73.60	0.00e+00	707.00
IUUC-Ncr-068909	Neurospora crassa	64.35	6.00e-157	545.00
IUUC-Nle-068994	Nomascus leucogenys	39.90	4.00e-84	305.00
IUUC-Opr-071079	Ochotona princeps	39.90	3.00e-84	305.00
IUUC-Ont-071971	Oreochromis niloticus	39.65	2.00e-83	302.00
IUUC-Oan-073135	Ornithorhynchus anatinus	40.92	4.00e-82	298.00
IUUC-Ocu-073982	Oryctolagus cuniculus	39.90	5.00e-84	304.00
IUUC-Oba-075297	Oryza barthii	33.91	2.00e-67	248.00
IUUC-Obr-076641	Oryza brachyantha	38.35	1.00e-81	295.00
IUUC-Ogl-077539	Oryza glaberrima	40.00	2.00e-62	231.00
IUUC-Ogu-078807	Oryza glumaepatula	33.91	3.00e-67	248.00
IUUC-Oin-079229	Oryza indica	38.12	6.00e-82	296.00
IUUC-Olo-080371	Oryza longistaminata	34.09	4.00e-67	247.00
IUUC-Ome-081149	Oryza meridionalis	33.66	2.00e-66	245.00
IUUC-Oni-082970	Oryza nivara	33.91	2.00e-67	248.00
IUUC-Opu-083415	Oryza punctata	33.91	1.00e-65	243.00
IUUC-Oru-085236	Oryza rufipogon	33.91	2.00e-67	248.00
IUUC-Ola-087421	Oryzias latipes	39.39	7.00e-82	296.00
IUUC-Olu-087821	Ostreococcus lucimarinus	36.69	4.00e-73	266.00
IUUC-Oga-088132	Otolemur garnettii	39.90	5.00e-84	304.00
IUUC-Oar-089513	Ovis aries	39.90	4.00e-84	305.00
IUUC-Ptr-090717	Pan troglodytes	39.90	3.00e-84	305.00
IUUC-Pan-092108	Papio anubis	39.90	3.00e-84	305.00
IUUC-Psi-093892	Pelodiscus sinensis	39.90	9.00e-84	303.00
IUUC-Pma-094561	Petromyzon marinus	40.40	7.00e-84	304.00
IUUC-Pno-094943	Phaeosphaeria nodorum	56.57	2.00e-143	500.00
IUUC-Ppa-095359	Physcomitrella patens	41.54	2.00e-86	311.00
IUUC-Pfo-096516	Poecilia formosa	39.55	6.00e-81	294.00
IUUC-Pab-097759	Pongo abelii	39.90	2.00e-84	305.00
IUUC-Pop-099553	Populus trichocarpa	38.00	2.00e-83	301.00
IUUC-Ppe-101957	Prunus persica	39.85	8.00e-85	306.00
IUUC-Pva-102918	Pteropus vampyrus	39.90	5.00e-84	304.00
IUUC-Pgr-103594	Puccinia graminis	41.09	2.00e-91	328.00
IUUC-Ptt-103879	Puccinia triticina	41.99	5.00e-79	286.00
IUUC-Pte-104419	Pyrenophora teres	60.77	1.00e-152	531.00
IUUC-Pyt-104718	Pyrenophora triticirepentis	61.14	3.00e-141	493.00
IUUC-Rno-105838	Rattus norvegicus	39.90	3.00e-84	305.00
IUUC-Sce-106331	Saccharomyces cerevisiae	38.64	4.00e-73	266.00
IUUC-Sha-107435	Sarcophilus harrisii	39.39	6.00e-84	304.00
IUUC-Sja-107796	Schizosaccharomyces japonicus	46.23	4.00e-99	353.00
IUUC-Spo-108163	Schizosaccharomyces pombe	45.61	2.00e-102	363.00
IUUC-Smo-109602	Selaginella moellendorffii	38.62	5.00e-84	302.00
IUUC-Sit-109729	Setaria italica	37.87	1.00e-80	292.00
IUUC-Sly-111679	Solanum lycopersicum	38.40	3.00e-84	304.00
IUUC-Sar-113157	Sorex araneus	39.90	4.00e-84	305.00
IUUC-Sbi-114853	Sorghum bicolor	37.56	2.00e-80	291.00
IUUC-Sre-115085	Sporisorium reilianum	42.27	4.00e-75	274.00
IUUC-Ssc-116286	Sus scrofa	39.55	6.00e-82	298.00
IUUC-Tgu-117219	Taeniopygia guttata	39.90	4.00e-84	305.00
IUUC-Tru-117550	Takifugu rubripes	39.65	5.00e-82	296.00
IUUC-Tsy-119294	Tarsius syrichta	39.90	3.00e-84	305.00
IUUC-Tni-120561	Tetraodon nigroviridis	39.65	1.00e-82	299.00
IUUC-Tca-121347	Theobroma cacao	38.90	4.00e-83	300.00
IUUC-Tre-122018	Trichoderma reesei	62.12	2.00e-151	527.00
IUUC-Tvi-122413	Trichoderma virens	61.66	6.00e-150	522.00
IUUC-Tae-123191	Triticum aestivum	38.29	1.00e-82	299.00
IUUC-Tme-127077	Tuber melanosporum	52.69	5.00e-120	422.00
IUUC-Tbe-127744	Tupaia belangeri	28.53	1.00e-35	143.00
IUUC-Ttr-128777	Tursiops truncatus	32.38	1.00e-57	217.00
IUUC-Uma-129568	Ustilago maydis	40.86	3.00e-74	270.00
IUUC-Vda-129834	Verticillium dahliae	58.82	9.00e-147	511.00
IUUC-Vvi-131360	Vitis vinifera	40.36	1.00e-83	302.00
IUUC-Xtr-132630	Xenopus tropicalis	40.40	1.00e-84	306.00
IUUC-Xma-133665	Xiphophorus maculatus	39.90	1.00e-82	300.00
IUUC-Yli-134556	Yarrowia lipolytica	37.42	8.00e-82	295.00
IUUC-Zma-135787	Zea mays	37.87	1.00e-81	295.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence