iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Kpa-049391

Ensembl Protein ID

CAY67814

UniProt Accession

C4QX41; C4QX41_KOMPG

Genbank Protein ID

CAY67814.1

Protein Name

Ubiquitin-conjugating enzyme involved in ER-associated protein degradation

Genbank Nucleotide ID

FN392319

Gene Name

PAS_chr1-1_0437

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PAS_chr1-1_0437	CAY67814	CAY67814

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.50e-28	97.3	9	131

Active Site

Position(s)	Description	Evidence
87	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk.eeekWspalsves 100
           Rl+ke+k +++++p+ i+a+p+++ ++ ew+++i Gp+dtpY++g+++  + fp++YPfkPP++k+ t+  ++ +++n+k+Cls+ + +++ W+p +sv++
   Q: 9    RLTKEYKLIQDNSPPFITAHPSES-NILEWHYVIDGPPDTPYNNGQYHGVLLFPSEYPFKPPSIKMCTP--NGRFQTNTKLCLSMSDfHPDLWNPGWSVTT 106
           99**********************.9*******************************************..9999999********889************ PP
   S: 101  vllsiqsll..aepnpesplneeaa 123
           +l+++ s++  ++  + s   ++a+
   Q: 107  ILVGLLSFMtgSDSTTGSISTSDAV 131
           *********4434444444444444 PP

Organism

Komagataella pastoris

Protein Sequence
(Fasta)

MATKQAHRRL TKEYKLIQDN SPPFITAHPS ESNILEWHYV IDGPPDTPYN NGQYHGVLLF 60
PSEYPFKPPS IKMCTPNGRF QTNTKLCLSM SDFHPDLWNP GWSVTTILVG LLSFMTGSDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTACGA AACAAGCTCA TCGACGACTT ACCAAAGAAT ATAAACTTAT ACAAGATAAT 60
TCTCCGCCAT TTATTACCGC CCATCCTAGT GAATCAAATA TTTTAGAATG GCATTATGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0006513--P:protein monoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

ppa:PAS_chr1-1_0437

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001180	Aegilops tauschii	49.32	2.00e-21	94.70
IUUC-Aml-002152	Ailuropoda melanoleuca	54.72	1.00e-47	180.00
IUUC-Atr-003156	Amborella trichopoda	56.13	7.00e-50	187.00
IUUC-Apl-004224	Anas platyrhynchos	55.84	2.00e-46	176.00
IUUC-Aca-005049	Anolis carolinensis	49.20	8.00e-47	177.00
IUUC-Aly-006195	Arabidopsis lyrata	53.55	1.00e-45	173.00
IUUC-Ath-006640	Arabidopsis thaliana	52.90	6.00e-45	171.00
IUUC-Ago-007987	Ashbya gossypii	52.15	3.00e-65	239.00
IUUC-Acl-008060	Aspergillus clavatus	58.60	6.00e-56	208.00
IUUC-Afl-008561	Aspergillus flavus	58.60	7.00e-56	207.00
IUUC-Afu-008860	Aspergillus fumigatus	58.60	1.00e-55	207.00
IUUC-Ani-009333	Aspergillus nidulans	62.76	1.00e-55	207.00
IUUC-Ang-009810	Aspergillus niger	59.24	7.00e-56	208.00
IUUC-Aor-010127	Aspergillus oryzae	58.60	7.00e-56	207.00
IUUC-Ate-010362	Aspergillus terreus	59.87	3.00e-56	209.00
IUUC-Ame-010627	Astyanax mexicanus	50.55	3.00e-47	179.00
IUUC-Bgr-012069	Blumeria graminis	56.29	2.00e-53	200.00
IUUC-Bta-012472	Bos taurus	54.72	8.00e-48	181.00
IUUC-Bci-013843	Botrytis cinerea	58.28	4.00e-54	202.00
IUUC-Bdi-014467	Brachypodium distachyon	55.10	3.00e-44	169.00
IUUC-Bol-016116	Brassica oleracea	52.90	8.00e-46	174.00
IUUC-Bra-017777	Brassica rapa	52.90	6.00e-45	171.00
IUUC-Cel-018278	Caenorhabditis elegans	49.13	4.00e-40	155.00
IUUC-Cja-018817	Callithrix jacchus	56.25	2.00e-39	153.00
IUUC-Cfa-020885	Canis familiaris	54.72	2.00e-47	180.00
IUUC-Cpo-022326	Cavia porcellus	54.72	1.00e-47	180.00
IUUC-Cre-022635	Chlamydomonas reinhardtii	60.26	3.00e-51	191.00
IUUC-Csa-023646	Chlorocebus sabaeus	54.72	1.00e-47	181.00
IUUC-Cho-025075	Choloepus hoffmanni	47.92	1.00e-32	129.00
IUUC-Cin-025389	Ciona intestinalis	54.04	9.00e-50	187.00
IUUC-Csv-026315	Ciona savignyi	54.94	5.00e-50	188.00
IUUC-Cgl-026602	Colletotrichum gloeosporioides	45.63	6.00e-53	198.00
IUUC-Cne-026808	Cryptococcus neoformans	53.54	8.00e-42	160.00
IUUC-Cme-027189	Cyanidioschyzon merolae	34.25	1.00e-19	88.20
IUUC-Dre-028455	Danio rerio	54.09	4.00e-47	179.00
IUUC-Dno-029667	Dasypus novemcinctus	54.09	4.00e-47	179.00
IUUC-Dor-030747	Dipodomys ordii	54.17	2.00e-40	157.00
IUUC-Dse-031231	Dothistroma septosporum	59.44	8.00e-52	194.00
IUUC-Dme-031841	Drosophila melanogaster	52.41	4.00e-46	175.00
IUUC-Ete-032258	Echinops telfairi	48.37	6.00e-43	165.00
IUUC-Eca-034179	Equus caballus	39.22	7.00e-31	125.00
IUUC-Eeu-034443	Erinaceus europaeus	57.80	3.00e-33	132.00
IUUC-Fca-036167	Felis catus	49.07	2.00e-36	144.00
IUUC-Fal-037114	Ficedula albicollis	55.84	3.00e-46	176.00
IUUC-Fox-037957	Fusarium oxysporum	58.06	2.00e-50	190.00
IUUC-Fso-038277	Fusarium solani	59.62	2.00e-55	206.00
IUUC-Gmo-039501	Gadus morhua	55.19	9.00e-47	177.00
IUUC-Ggr-040010	Gaeumannomyces graminis	61.54	3.00e-52	196.00
IUUC-Gga-041257	Gallus gallus	55.84	1.00e-46	177.00
IUUC-Gac-041433	Gasterosteus aculeatus	55.84	3.00e-47	179.00
IUUC-Gma-044091	Glycine max	44.24	2.00e-47	179.00
IUUC-Ggo-044437	Gorilla gorilla	56.25	1.00e-38	151.00
IUUC-Hsa-046693	Homo sapiens	54.72	2.00e-47	180.00
IUUC-Hvu-047328	Hordeum vulgare	38.64	1.00e-31	128.00
IUUC-Itr-048477	Ictidomys tridecemlineatus	48.19	6.00e-48	181.00
IUUC-Lch-049617	Latimeria chalumnae	56.49	7.00e-47	178.00
IUUC-Lpe-050949	Leersia perrieri	51.90	5.00e-43	165.00
IUUC-Loc-052157	Lepisosteus oculatus	52.98	2.00e-47	179.00
IUUC-Lma-053128	Leptosphaeria maculans	57.62	2.00e-51	192.00
IUUC-Laf-054455	Loxodonta africana	54.72	9.00e-48	181.00
IUUC-Mcc-054756	Macaca mulatta	54.72	1.00e-47	181.00
IUUC-Meu-056106	Macropus eugenii	57.80	3.00e-33	132.00
IUUC-Mor-057202	Magnaporthe oryzae	61.11	6.00e-52	194.00
IUUC-Mpo-057349	Magnaporthe poae	61.54	4.00e-52	195.00
IUUC-Mtr-058271	Medicago truncatula	49.42	6.00e-43	164.00
IUUC-Mla-058894	Melampsora laricipopulina	58.06	2.00e-52	195.00
IUUC-Mga-059493	Meleagris gallopavo	55.84	1.00e-46	177.00
IUUC-Mvi-060232	Microbotryum violaceum	58.06	8.00e-53	197.00
IUUC-Mmr-060957	Microcebus murinus	54.09	9.00e-47	177.00
IUUC-Mdo-062141	Monodelphis domestica	54.72	2.00e-47	180.00
IUUC-Mmu-063882	Mus musculus	54.72	6.00e-48	181.00
IUUC-Mac-064530	Musa acuminata	48.50	5.00e-47	178.00
IUUC-Mpu-065902	Mustela putorius furo	54.72	2.00e-47	180.00
IUUC-Mlu-068008	Myotis lucifugus	54.09	7.00e-46	174.00
IUUC-Nfi-068515	Neosartorya fischeri	58.60	9.00e-56	207.00
IUUC-Ncr-068755	Neurospora crassa	57.72	2.00e-52	196.00
IUUC-Nle-069166	Nomascus leucogenys	39.22	2.00e-30	124.00
IUUC-Opr-071201	Ochotona princeps	48.95	5.00e-34	135.00
IUUC-Ont-071311	Oreochromis niloticus	55.84	3.00e-47	179.00
IUUC-Oan-073310	Ornithorhynchus anatinus	54.72	2.00e-47	180.00
IUUC-Ocu-074514	Oryctolagus cuniculus	47.67	3.00e-47	179.00
IUUC-Oba-075200	Oryza barthii	49.70	5.00e-43	165.00
IUUC-Obr-076396	Oryza brachyantha	51.27	4.00e-43	165.00
IUUC-Ogl-077398	Oryza glaberrima	49.70	5.00e-43	165.00
IUUC-Ogu-078362	Oryza glumaepatula	49.70	5.00e-43	165.00
IUUC-Oin-079625	Oryza indica	49.70	5.00e-43	165.00
IUUC-Olo-080620	Oryza longistaminata	60.49	2.00e-27	113.00
IUUC-Ome-081187	Oryza meridionalis	49.70	6.00e-43	165.00
IUUC-Oni-082271	Oryza nivara	49.70	5.00e-43	165.00
IUUC-Opu-083487	Oryza punctata	49.70	6.00e-43	164.00
IUUC-Oru-085263	Oryza rufipogon	49.70	5.00e-43	165.00
IUUC-Osa-085694	Oryza sativa	49.70	5.00e-43	165.00
IUUC-Ola-086450	Oryzias latipes	52.38	3.00e-47	179.00
IUUC-Olu-087733	Ostreococcus lucimarinus	38.85	4.00e-28	115.00
IUUC-Oga-088054	Otolemur garnettii	49.14	2.00e-42	163.00
IUUC-Oar-089486	Ovis aries	54.72	9.00e-48	181.00
IUUC-Ptr-091314	Pan troglodytes	39.22	9.00e-31	125.00
IUUC-Pan-092633	Papio anubis	54.72	1.00e-47	181.00
IUUC-Psi-093668	Pelodiscus sinensis	37.75	2.00e-29	120.00
IUUC-Pno-095025	Phaeosphaeria nodorum	56.38	6.00e-52	195.00
IUUC-Ppa-095641	Physcomitrella patens	49.08	4.00e-46	175.00
IUUC-Pfo-096423	Poecilia formosa	55.84	2.00e-46	177.00
IUUC-Pab-097771	Pongo abelii	54.72	1.00e-47	181.00
IUUC-Pop-099714	Populus trichocarpa	45.93	4.00e-48	182.00
IUUC-Pca-100493	Procavia capensis	45.53	5.00e-26	108.00
IUUC-Ppe-102054	Prunus persica	50.29	2.00e-45	173.00
IUUC-Pva-102224	Pteropus vampyrus	54.72	1.00e-47	180.00
IUUC-Pgr-103530	Puccinia graminis	52.90	1.00e-49	186.00
IUUC-Ptt-103894	Puccinia triticina	56.06	4.00e-46	174.00
IUUC-Pte-104166	Pyrenophora teres	58.74	9.00e-51	191.00
IUUC-Pyt-104570	Pyrenophora triticirepentis	58.74	9.00e-51	191.00
IUUC-Rno-105593	Rattus norvegicus	54.72	6.00e-48	181.00
IUUC-Sce-106212	Saccharomyces cerevisiae	51.21	1.00e-71	260.00
IUUC-Sha-106767	Sarcophilus harrisii	55.35	1.00e-47	181.00
IUUC-Sja-107907	Schizosaccharomyces japonicus	48.89	2.00e-59	220.00
IUUC-Spo-108094	Schizosaccharomyces pombe	57.14	8.00e-56	207.00
IUUC-Ssl-108556	Sclerotinia sclerotiorum	58.94	4.00e-55	205.00
IUUC-Smo-108965	Selaginella moellendorffii	49.20	2.00e-48	182.00
IUUC-Sit-110407	Setaria italica	57.64	4.00e-45	172.00
IUUC-Sly-110845	Solanum lycopersicum	50.00	2.00e-42	163.00
IUUC-Stu-112336	Solanum tuberosum	51.83	1.00e-42	164.00
IUUC-Sar-113063	Sorex araneus	39.74	1.00e-31	127.00
IUUC-Sbi-114327	Sorghum bicolor	57.64	3.00e-45	172.00
IUUC-Sre-115170	Sporisorium reilianum	55.15	2.00e-45	173.00
IUUC-Ssc-116385	Sus scrofa	54.72	8.00e-48	181.00
IUUC-Tgu-117041	Taeniopygia guttata	55.84	2.00e-46	177.00
IUUC-Tru-117697	Takifugu rubripes	56.49	8.00e-48	181.00
IUUC-Tsy-119024	Tarsius syrichta	47.02	4.00e-40	155.00
IUUC-Tni-120466	Tetraodon nigroviridis	49.43	2.00e-45	173.00
IUUC-Tca-121569	Theobroma cacao	52.87	8.00e-45	171.00
IUUC-Tre-121882	Trichoderma reesei	61.74	2.00e-55	206.00
IUUC-Tvi-122466	Trichoderma virens	61.07	5.00e-55	205.00
IUUC-Tae-124592	Triticum aestivum	48.84	2.00e-43	166.00
IUUC-Tur-126536	Triticum urartu	54.00	2.00e-43	166.00
IUUC-Tme-127051	Tuber melanosporum	61.74	2.00e-56	209.00
IUUC-Tbe-127743	Tupaia belangeri	39.07	1.00e-30	124.00
IUUC-Ttr-128466	Tursiops truncatus	54.72	8.00e-48	181.00
IUUC-Uma-129383	Ustilago maydis	54.55	6.00e-45	171.00
IUUC-Vda-130013	Verticillium dahliae	57.82	1.00e-50	190.00
IUUC-Vpa-130404	Vicugna pacos	39.46	3.00e-31	126.00
IUUC-Vvi-131251	Vitis vinifera	52.90	2.00e-42	163.00
IUUC-Xtr-132408	Xenopus tropicalis	54.72	2.00e-47	179.00
IUUC-Xma-133893	Xiphophorus maculatus	55.84	9.00e-47	177.00
IUUC-Yli-134618	Yarrowia lipolytica	62.34	4.00e-59	218.00
IUUC-Zma-135216	Zea mays	51.48	2.00e-45	173.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence