iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059361

Ensembl Protein ID

ENSMGAP00000005637.1

UniProt Accession

G1N226; G1N226_MELGA

Protein Name

Uncharacterized protein

Gene Name

HGS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000005652.1	ENSMGAT00000006377.1	ENSMGAP00000005637.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/VHS	7.60e-50	168.1	2	126

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/VHS

   S: 5    lvtsedwelileicdliqetkegakdalralrkrinnknphvalraLtlLdscvsnCgkkfhvevaskdlleelrellknenepkvieK 93
           l+ ++dwe+il+icd+i++ +++ak+a++a++k++n+knphval+aL++++s+v+nCg+++h+eva+k+++eel+e+lk+++e+ v+ K
   Q: 2    LLLETDWESILQICDMIRQGDTQAKYAVNAIKKKVNDKNPHVALYALEVMESVVKNCGQTVHDEVANKQTMEELKEILKRQVETSVRSK 90
           6789************************************************************************************* PP
   S: 94   lkalivsWadelknepalslivaliktlkeeGlefp 129
           +++li++Wa++++nep++++++++++ +k eG++fp
   Q: 91   ILNLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFP 126
           ***********************************8 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

QLLLETDWES ILQICDMIRQ GDTQAKYAVN AIKKKVNDKN PHVALYALEV MESVVKNCGQ 60
TVHDEVANKQ TMEELKEILK RQVETSVRSK ILNLIQAWAH AFRNEPKYKV VQDTYQIMKV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCTCCTGC TGGAGACGGA CTGGGAGTCC ATCCTGCAGA TCTGCGACAT GATCCGTCAG 60
GGAGACACGC AGTAAGCGCC CCTTTGCGTT TTGGTTTAAG CTGTGAGAAC GGATCTGCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008942--ENTH_VHS
IPR024641--HRS_helical
IPR017073--Ubi-bd_Hrs_VPS27
IPR003903--UIM_dom
IPR002014--VHS_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50330--UIM
PS50179--VHS
PS50178--ZF_FYVE

Pfam

PF01363--FYVE
PF12210--Hrs_helical
PF00790--VHS

SMART

SM00064--FYVE
SM00288--VHS

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0070062--C:extracellular exosome
GO:0005764--C:lysosome
GO:0046872--F:metal ion binding
GO:0010324--P:membrane invagination
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:1903543--P:positive regulation of exosomal secretion
GO:0010628--P:positive regulation of gene expression
GO:0072657--P:protein localization to membrane
GO:0006622--P:protein targeting to lysosome
GO:0043405--P:regulation of MAP kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001518	Ailuropoda melanoleuca	77.45	0.00e+00	874.00
IUUC-Apl-003662	Anas platyrhynchos	93.29	0.00e+00	1061.00
IUUC-Aca-004940	Anolis carolinensis	85.28	0.00e+00	1163.00
IUUC-Ago-007931	Ashbya gossypii	31.73	5.00e-27	115.00
IUUC-Acl-008274	Aspergillus clavatus	34.87	3.00e-37	149.00
IUUC-Afl-008521	Aspergillus flavus	32.41	3.00e-39	156.00
IUUC-Afu-008774	Aspergillus fumigatus	31.62	2.00e-38	153.00
IUUC-Ani-009445	Aspergillus nidulans	32.41	5.00e-39	155.00
IUUC-Ang-009863	Aspergillus niger	32.41	2.00e-39	157.00
IUUC-Ate-010444	Aspergillus terreus	33.99	2.00e-40	160.00
IUUC-Ame-011111	Astyanax mexicanus	78.38	0.00e+00	905.00
IUUC-Bgr-012087	Blumeria graminis	33.20	5.00e-40	159.00
IUUC-Bta-012506	Bos taurus	83.29	0.00e+00	1037.00
IUUC-Bci-013782	Botrytis cinerea	36.73	3.00e-38	153.00
IUUC-Cel-018493	Caenorhabditis elegans	53.03	1.00e-64	240.00
IUUC-Cja-019998	Callithrix jacchus	78.17	0.00e+00	943.00
IUUC-Cfa-020615	Canis familiaris	79.82	0.00e+00	945.00
IUUC-Cpo-022019	Cavia porcellus	83.04	0.00e+00	1069.00
IUUC-Csa-023596	Chlorocebus sabaeus	79.95	0.00e+00	946.00
IUUC-Cin-025488	Ciona intestinalis	47.86	2.00e-121	429.00
IUUC-Csv-025802	Ciona savignyi	48.24	5.00e-110	390.00
IUUC-Cgl-026560	Colletotrichum gloeosporioides	37.24	1.00e-37	150.00
IUUC-Cne-026847	Cryptococcus neoformans	29.08	1.00e-34	140.00
IUUC-Dre-028353	Danio rerio	76.60	0.00e+00	902.00
IUUC-Dno-029005	Dasypus novemcinctus	79.92	0.00e+00	1012.00
IUUC-Dor-030280	Dipodomys ordii	81.40	0.00e+00	1009.00
IUUC-Dse-031238	Dothistroma septosporum	40.31	2.00e-42	167.00
IUUC-Dme-031952	Drosophila melanogaster	48.02	4.00e-74	272.00
IUUC-Ete-032235	Echinops telfairi	94.58	2.00e-119	422.00
IUUC-Eca-033873	Equus caballus	81.56	0.00e+00	1030.00
IUUC-Eeu-034652	Erinaceus europaeus	95.06	6.00e-94	338.00
IUUC-Fca-036563	Felis catus	79.61	0.00e+00	981.00
IUUC-Fal-036649	Ficedula albicollis	91.90	0.00e+00	1147.00
IUUC-Fox-037962	Fusarium oxysporum	32.14	3.00e-37	149.00
IUUC-Fso-038396	Fusarium solani	32.81	9.00e-38	151.00
IUUC-Gmo-039510	Gadus morhua	71.96	0.00e+00	863.00
IUUC-Ggr-039938	Gaeumannomyces graminis	32.38	3.00e-35	143.00
IUUC-Gga-040201	Gallus gallus	96.48	0.00e+00	1244.00
IUUC-Gac-041459	Gasterosteus aculeatus	76.28	0.00e+00	919.00
IUUC-Ggo-044573	Gorilla gorilla	80.39	0.00e+00	1011.00
IUUC-Hsa-046009	Homo sapiens	80.65	0.00e+00	1058.00
IUUC-Itr-049065	Ictidomys tridecemlineatus	80.52	0.00e+00	1081.00
IUUC-Kpa-049327	Komagataella pastoris	32.20	8.00e-32	131.00
IUUC-Lch-049944	Latimeria chalumnae	78.37	1.00e-166	578.00
IUUC-Loc-051850	Lepisosteus oculatus	80.69	0.00e+00	1007.00
IUUC-Lma-053252	Leptosphaeria maculans	36.73	1.00e-39	157.00
IUUC-Laf-053346	Loxodonta africana	74.32	0.00e+00	903.00
IUUC-Mcc-055789	Macaca mulatta	82.60	0.00e+00	1008.00
IUUC-Meu-056329	Macropus eugenii	67.82	2.00e-149	522.00
IUUC-Mor-057205	Magnaporthe oryzae	36.79	1.00e-36	147.00
IUUC-Mpo-057295	Magnaporthe poae	32.36	9.00e-38	151.00
IUUC-Mla-058849	Melampsora laricipopulina	33.33	1.00e-30	128.00
IUUC-Mvi-060561	Microbotryum violaceum	36.14	2.00e-34	140.00
IUUC-Mmr-061122	Microcebus murinus	86.83	0.00e+00	898.00
IUUC-Mdo-062171	Monodelphis domestica	85.64	0.00e+00	1092.00
IUUC-Mmu-063952	Mus musculus	82.44	0.00e+00	1120.00
IUUC-Mpu-065852	Mustela putorius furo	80.03	0.00e+00	956.00
IUUC-Mlu-066996	Myotis lucifugus	72.62	5.00e-126	444.00
IUUC-Nfi-068539	Neosartorya fischeri	31.62	1.00e-38	154.00
IUUC-Ncr-068726	Neurospora crassa	38.78	2.00e-38	153.00
IUUC-Nle-070148	Nomascus leucogenys	75.78	0.00e+00	905.00
IUUC-Opr-070833	Ochotona princeps	63.48	4.00e-125	441.00
IUUC-Ont-071261	Oreochromis niloticus	76.72	0.00e+00	930.00
IUUC-Oan-073684	Ornithorhynchus anatinus	69.37	1.00e-145	509.00
IUUC-Ola-087570	Oryzias latipes	74.52	0.00e+00	931.00
IUUC-Oga-089087	Otolemur garnettii	81.81	0.00e+00	947.00
IUUC-Oar-089534	Ovis aries	83.17	0.00e+00	1039.00
IUUC-Ptr-091654	Pan troglodytes	75.71	0.00e+00	915.00
IUUC-Pan-092652	Papio anubis	80.34	0.00e+00	1009.00
IUUC-Pno-095125	Phaeosphaeria nodorum	37.24	4.00e-39	155.00
IUUC-Pfo-096757	Poecilia formosa	76.92	0.00e+00	891.00
IUUC-Pab-097788	Pongo abelii	85.62	0.00e+00	720.00
IUUC-Pca-100145	Procavia capensis	70.76	0.00e+00	798.00
IUUC-Pva-102965	Pteropus vampyrus	79.56	0.00e+00	964.00
IUUC-Pgr-103609	Puccinia graminis	34.18	9.00e-34	137.00
IUUC-Ptt-103865	Puccinia triticina	35.42	2.00e-34	140.00
IUUC-Pte-104095	Pyrenophora teres	35.71	2.00e-38	153.00
IUUC-Pyt-104668	Pyrenophora triticirepentis	36.22	2.00e-38	153.00
IUUC-Rno-105125	Rattus norvegicus	83.77	0.00e+00	1033.00
IUUC-Sce-106192	Saccharomyces cerevisiae	29.65	2.00e-27	117.00
IUUC-Sha-107066	Sarcophilus harrisii	86.61	0.00e+00	1062.00
IUUC-Sja-107931	Schizosaccharomyces japonicus	33.33	1.00e-38	154.00
IUUC-Spo-108220	Schizosaccharomyces pombe	37.63	1.00e-37	150.00
IUUC-Smo-109345	Selaginella moellendorffii	37.78	1.00e-18	87.00
IUUC-Stu-112464	Solanum tuberosum	45.90	3.00e-13	70.50
IUUC-Sar-113393	Sorex araneus	90.86	6.00e-103	367.00
IUUC-Sre-114986	Sporisorium reilianum	39.80	6.00e-41	162.00
IUUC-Tgu-117505	Taeniopygia guttata	90.46	0.00e+00	1102.00
IUUC-Tru-118494	Takifugu rubripes	77.75	0.00e+00	965.00
IUUC-Tsy-119626	Tarsius syrichta	95.60	9.00e-48	184.00
IUUC-Tni-120174	Tetraodon nigroviridis	72.67	0.00e+00	950.00
IUUC-Tre-122191	Trichoderma reesei	32.56	1.00e-37	151.00
IUUC-Tvi-122318	Trichoderma virens	32.17	6.00e-38	152.00
IUUC-Tme-126914	Tuber melanosporum	34.63	1.00e-41	164.00
IUUC-Ttr-129095	Tursiops truncatus	83.61	0.00e+00	1060.00
IUUC-Uma-129475	Ustilago maydis	30.42	8.00e-37	148.00
IUUC-Vda-129908	Verticillium dahliae	34.01	6.00e-33	135.00
IUUC-Xtr-131900	Xenopus tropicalis	78.64	0.00e+00	1033.00
IUUC-Xma-133124	Xiphophorus maculatus	76.37	0.00e+00	925.00
IUUC-Yli-134682	Yarrowia lipolytica	34.80	2.00e-31	130.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence