iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-134165

Ensembl Protein ID

ENSXMAP00000008420.1

UniProt Accession

M4A1S6; M4A1S6_XIPMA

Genbank Protein ID

ENSXMAP00000008420

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01001137

Gene Name

UBE2K (1 of many)

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000008397.1	ENSXMAT00000008432.1	ENSXMAP00000008420.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.80e-46	156.8	8	146
UBD/Alpha-Helix/UBA	1.00e-09	38.3	161	199
UBD/UBC-like/UBD_UBC	4.60e-72	240.6	8	149

Active Site

Position(s)	Description	Evidence
92	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    Rlkkelkel...ekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsi 85
           R+k+e+ke+   e++++++i++++vde ++te++ +i Gp+dtpYegg ++lei++pe+YPf+PPkv+f+tki+hPn+++  G++Cl+i
   Q: 8    RIKREFKEVlksEETSKNQIKVDLVDE-NFTELKGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVtGAICLDI 95
           7888888873335556699********.9***************************************************99******* PP
   S: 86   lkeeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           lk  ++W +a+++++vlls+q+lla ++p++p+++ +a+++k+n+e++k++++
   Q: 96   LK--DQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTAK 146
           *9..*********************************************9986 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraannnleaAveyLld 40
           e++ k+++l++MGF++++++ aL + ++++e A+e+Ll+
   Q: 161  EYTRKIDKLCAMGFEKNAVIVALSSKSWDVETATELLLS 199
           57889********************************97 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeea...qisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpnins.ngsicldil 85
           rik+e+k++l++ee+   qi++dlvd++++el+++iagppd+pyegg+++l+ik+p++ypf+ppkv+fitki+hpni+s +g+icldil
   Q: 8    RIKREFKEVLKSEETsknQIKVDLVDENFTELKGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSvTGAICLDIL 96
           8*************9999*********************************************************************** PP
   S: 86   rsqwsaaltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           ++qw+aa+tl++vllsl++lla+aepddp++a++a++yk+++e++k++a++w+
   Q: 97   KDQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTAKLWS 149
           ****************************************************5 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MANIAVQRIK REFKEVLKSE ETSKNQIKVD LVDENFTELK GEIAGPPDTP YEGGRYQLEI 60
KIPETYPFNP PKVRFITKIW HPNISSVTGA ICLDILKDQW AAAMTLRTVL LSLQALLAAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATCACATGA CCCCGTCTCC TCTAGACTGC ATGCAGTTTT TGGTATTAAA ATGTTTTCTG 60
TTCTACCAAC CATTGTGTTG TTGCTGCATA TTTGAGATGA CAGACTCACG TTAAGCTACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50030--UBA
PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00627--UBA
PF00179--UQ_con

SMART

SM00165--UBA

Gene Ontology

GO:0005524--F:ATP binding

KEGG

xma:102229303

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000621	Aegilops tauschii	51.55	3.00e-28	118.00
IUUC-Apl-004122	Anas platyrhynchos	88.50	3.00e-94	337.00
IUUC-Ath-006637	Arabidopsis thaliana	46.38	5.00e-41	160.00
IUUC-Ago-007714	Ashbya gossypii	45.70	9.00e-39	152.00
IUUC-Acl-008189	Aspergillus clavatus	48.39	3.00e-27	115.00
IUUC-Ame-011454	Astyanax mexicanus	99.00	5.00e-109	386.00
IUUC-Bgr-012255	Blumeria graminis	47.13	3.00e-33	135.00
IUUC-Bra-016805	Brassica rapa	47.72	1.00e-44	172.00
IUUC-Cel-018353	Caenorhabditis elegans	53.77	2.00e-58	218.00
IUUC-Cja-019051	Callithrix jacchus	95.50	1.00e-105	375.00
IUUC-Cre-022987	Chlamydomonas reinhardtii	48.98	1.00e-41	162.00
IUUC-Cho-024276	Choloepus hoffmanni	91.84	1.00e-70	258.00
IUUC-Cin-025598	Ciona intestinalis	61.22	3.00e-56	211.00
IUUC-Csv-025831	Ciona savignyi	62.76	1.00e-54	205.00
IUUC-Cgl-026449	Colletotrichum gloeosporioides	41.49	5.00e-34	137.00
IUUC-Cne-027068	Cryptococcus neoformans	41.38	6.00e-41	160.00
IUUC-Dre-028139	Danio rerio	98.00	2.00e-108	384.00
IUUC-Dno-029169	Dasypus novemcinctus	89.50	1.00e-98	352.00
IUUC-Ete-032868	Echinops telfairi	87.00	7.00e-85	306.00
IUUC-Eeu-035103	Erinaceus europaeus	67.97	4.00e-46	176.00
IUUC-Fox-037969	Fusarium oxysporum	43.64	5.00e-33	134.00
IUUC-Fso-038296	Fusarium solani	42.00	1.00e-35	142.00
IUUC-Gmo-039135	Gadus morhua	99.00	2.00e-108	384.00
IUUC-Ggr-039768	Gaeumannomyces graminis	40.10	3.00e-26	111.00
IUUC-Gac-041503	Gasterosteus aculeatus	99.50	2.00e-109	387.00
IUUC-Kpa-049297	Komagataella pastoris	50.33	2.00e-34	139.00
IUUC-Loc-052549	Lepisosteus oculatus	97.50	5.00e-108	383.00
IUUC-Mor-056946	Magnaporthe oryzae	37.93	9.00e-24	103.00
IUUC-Mpo-057441	Magnaporthe poae	41.59	3.00e-26	112.00
IUUC-Mvi-060346	Microbotryum violaceum	42.00	6.00e-34	137.00
IUUC-Mdo-062458	Monodelphis domestica	95.00	6.00e-104	369.00
IUUC-Mpu-066407	Mustela putorius furo	96.00	4.00e-106	377.00
IUUC-Ncr-068749	Neurospora crassa	40.49	3.00e-38	151.00
IUUC-Ont-071595	Oreochromis niloticus	99.50	2.00e-109	387.00
IUUC-Oan-073058	Ornithorhynchus anatinus	95.27	8.00e-76	275.00
IUUC-Ola-087043	Oryzias latipes	99.50	2.00e-109	387.00
IUUC-Olu-087846	Ostreococcus lucimarinus	46.63	4.00e-42	164.00
IUUC-Oar-089673	Ovis aries	88.89	3.00e-97	347.00
IUUC-Pfo-096174	Poecilia formosa	99.50	2.00e-109	387.00
IUUC-Pca-100782	Procavia capensis	95.50	2.00e-104	371.00
IUUC-Pva-102147	Pteropus vampyrus	67.05	5.00e-55	206.00
IUUC-Sce-106394	Saccharomyces cerevisiae	43.68	2.00e-36	145.00
IUUC-Sha-106624	Sarcophilus harrisii	90.00	5.00e-101	359.00
IUUC-Sre-115046	Sporisorium reilianum	39.70	6.00e-37	147.00
IUUC-Tru-118196	Takifugu rubripes	87.11	2.00e-104	371.00
IUUC-Tsy-119208	Tarsius syrichta	93.94	4.00e-103	366.00
IUUC-Tni-119667	Tetraodon nigroviridis	99.00	3.00e-109	387.00
IUUC-Tre-122053	Trichoderma reesei	37.13	8.00e-31	127.00
IUUC-Tme-127024	Tuber melanosporum	50.32	7.00e-39	153.00
IUUC-Tbe-127752	Tupaia belangeri	92.50	1.00e-101	361.00
IUUC-Ttr-128287	Tursiops truncatus	95.53	2.00e-94	337.00
IUUC-Uma-129512	Ustilago maydis	39.71	5.00e-37	147.00
IUUC-Vda-129947	Verticillium dahliae	36.71	2.00e-31	129.00
IUUC-Yli-134523	Yarrowia lipolytica	44.00	2.00e-34	138.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence