iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-034016

Ensembl Protein ID

ENSECAP00000010939.1

UniProt Accession

F6PUT4; F6PUT4_HORSE

Protein Name

Non-specific serine/threonine protein kinase

Gene Name

PRKAA2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000012967.1	ENSECAT00000013755.1	ENSECAP00000010939.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	47.36	4.00e-117	418.00	IUUC-Ath-007014

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Equus caballus

Protein Sequence
(Fasta)

VGEHQLTGHK VAVKILNRQK IRSLDVVGKI KREIQNLKLF RHPHIIKLYQ VISTPTDFFM 60
VMEYVSGGEL FDYICKHGRV EEMEARRLFQ QILSAVDYCH RHMVVHRDLK PENVLLDAQM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTGGAGAAC ATCAATTGAC AGGCCATAAA GTGGCAGTTA AAATCTTAAA TAGACAGAAG 60
ATTCGCAGTT TAGATGTCGT TGGAAAAATA AAACGAGAAA TTCAAAATCT AAAACTCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR032270--AMPK_C
IPR028375--KA1/Ssp2_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF16579--AdenylateSensor
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005794--C:Golgi apparatus
GO:0016607--C:nuclear speck
GO:0031588--C:nucleotide-activated protein kinase complex
GO:0005634--C:nucleus
GO:0004679--F:AMP-activated protein kinase activity
GO:0005524--F:ATP binding
GO:0003682--F:chromatin binding
GO:0035174--F:histone serine kinase activity
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0035690--P:cellular response to drug
GO:0042149--P:cellular response to glucose starvation
GO:0071380--P:cellular response to prostaglandin E stimulus
GO:0042593--P:glucose homeostasis
GO:0035404--P:histone-serine phosphorylation
GO:0035556--P:intracellular signal transduction
GO:0008610--P:lipid biosynthetic process
GO:0043066--P:negative regulation of apoptotic process
GO:0032007--P:negative regulation of TOR signaling
GO:0010508--P:positive regulation of autophagy
GO:0042752--P:regulation of circadian rhythm
GO:0010468--P:regulation of gene expression
GO:0016241--P:regulation of macroautophagy
GO:0014850--P:response to muscle activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000713	Aegilops tauschii	46.92	9.00e-116	410.00
IUUC-Apl-003395	Anas platyrhynchos	93.68	0.00e+00	1023.00
IUUC-Aca-004480	Anolis carolinensis	93.48	0.00e+00	963.00
IUUC-Aly-006289	Arabidopsis lyrata	47.46	3.00e-118	418.00
IUUC-Ath-007014	Arabidopsis thaliana	47.57	2.00e-118	419.00
IUUC-Ago-007957	Ashbya gossypii	41.94	3.00e-108	385.00
IUUC-Acl-008103	Aspergillus clavatus	61.96	5.00e-96	345.00
IUUC-Afl-008555	Aspergillus flavus	61.57	2.00e-96	347.00
IUUC-Afu-008949	Aspergillus fumigatus	48.33	4.00e-96	345.00
IUUC-Ani-009408	Aspergillus nidulans	64.34	2.00e-96	346.00
IUUC-Ang-009551	Aspergillus niger	61.96	4.00e-96	345.00
IUUC-Aor-010176	Aspergillus oryzae	61.57	2.00e-96	347.00
IUUC-Ate-010287	Aspergillus terreus	61.96	5.00e-96	345.00
IUUC-Ame-011019	Astyanax mexicanus	85.85	0.00e+00	949.00
IUUC-Bgr-012045	Blumeria graminis	61.54	7.00e-95	341.00
IUUC-Bci-013774	Botrytis cinerea	46.48	3.00e-97	349.00
IUUC-Bdi-014319	Brachypodium distachyon	46.31	1.00e-116	413.00
IUUC-Bol-016242	Brassica oleracea	47.65	5.00e-121	427.00
IUUC-Bra-016750	Brassica rapa	47.65	2.00e-121	429.00
IUUC-Cel-018518	Caenorhabditis elegans	58.52	3.00e-170	592.00
IUUC-Cja-019386	Callithrix jacchus	97.89	0.00e+00	1032.00
IUUC-Cpo-021805	Cavia porcellus	98.27	0.00e+00	1038.00
IUUC-Cre-022915	Chlamydomonas reinhardtii	54.64	4.00e-89	320.00
IUUC-Csa-024267	Chlorocebus sabaeus	97.89	0.00e+00	1021.00
IUUC-Cin-025550	Ciona intestinalis	60.61	0.00e+00	635.00
IUUC-Csv-026139	Ciona savignyi	59.24	0.00e+00	632.00
IUUC-Cne-027044	Cryptococcus neoformans	51.09	4.00e-100	358.00
IUUC-Dor-030578	Dipodomys ordii	97.50	0.00e+00	1029.00
IUUC-Dse-031507	Dothistroma septosporum	64.75	4.00e-98	352.00
IUUC-Dme-031704	Drosophila melanogaster	59.05	0.00e+00	644.00
IUUC-Fox-038073	Fusarium oxysporum	52.85	1.00e-98	353.00
IUUC-Fso-038236	Fusarium solani	52.11	3.00e-95	342.00
IUUC-Ggr-039987	Gaeumannomyces graminis	49.12	1.00e-95	344.00
IUUC-Gga-040546	Gallus gallus	91.94	0.00e+00	996.00
IUUC-Gac-041822	Gasterosteus aculeatus	83.43	0.00e+00	889.00
IUUC-Ggo-045303	Gorilla gorilla	98.08	0.00e+00	1036.00
IUUC-Hsa-045746	Homo sapiens	98.08	0.00e+00	1036.00
IUUC-Hvu-047406	Hordeum vulgare	47.02	3.00e-117	415.00
IUUC-Itr-048134	Ictidomys tridecemlineatus	98.08	0.00e+00	1035.00
IUUC-Kpa-049190	Komagataella pastoris	45.13	1.00e-114	406.00
IUUC-Loc-052928	Lepisosteus oculatus	90.04	0.00e+00	971.00
IUUC-Lma-053054	Leptosphaeria maculans	64.75	6.00e-99	355.00
IUUC-Laf-053459	Loxodonta africana	97.70	0.00e+00	1031.00
IUUC-Mcc-055862	Macaca mulatta	98.08	0.00e+00	1036.00
IUUC-Mpo-057302	Magnaporthe poae	49.27	9.00e-96	344.00
IUUC-Mga-059206	Meleagris gallopavo	91.75	0.00e+00	995.00
IUUC-Mvi-060337	Microbotryum violaceum	41.20	8.00e-101	361.00
IUUC-Mmr-061619	Microcebus murinus	96.93	0.00e+00	1018.00
IUUC-Mdo-062160	Monodelphis domestica	93.86	0.00e+00	1001.00
IUUC-Mmu-063406	Mus musculus	96.74	0.00e+00	1019.00
IUUC-Mac-064518	Musa acuminata	44.65	1.00e-113	403.00
IUUC-Mpu-066326	Mustela putorius furo	98.66	0.00e+00	1040.00
IUUC-Mlu-067968	Myotis lucifugus	97.32	0.00e+00	996.00
IUUC-Nfi-068493	Neosartorya fischeri	61.96	3.00e-96	345.00
IUUC-Ncr-068665	Neurospora crassa	41.89	2.00e-100	359.00
IUUC-Nle-070158	Nomascus leucogenys	97.89	0.00e+00	1034.00
IUUC-Ont-071395	Oreochromis niloticus	86.10	0.00e+00	934.00
IUUC-Ogl-077718	Oryza glaberrima	49.30	1.00e-115	410.00
IUUC-Oin-079889	Oryza indica	45.23	3.00e-116	412.00
IUUC-Oni-082211	Oryza nivara	46.38	7.00e-119	421.00
IUUC-Ola-087169	Oryzias latipes	84.00	0.00e+00	907.00
IUUC-Ptr-090741	Pan troglodytes	98.08	0.00e+00	1036.00
IUUC-Pno-095030	Phaeosphaeria nodorum	63.97	2.00e-97	349.00
IUUC-Pfo-096295	Poecilia formosa	85.14	0.00e+00	920.00
IUUC-Pab-098023	Pongo abelii	98.08	0.00e+00	1036.00
IUUC-Pop-100042	Populus trichocarpa	47.16	6.00e-120	424.00
IUUC-Ppe-101642	Prunus persica	47.93	1.00e-117	416.00
IUUC-Pva-102470	Pteropus vampyrus	97.12	0.00e+00	1019.00
IUUC-Pgr-103406	Puccinia graminis	61.63	3.00e-85	309.00
IUUC-Ptt-103713	Puccinia triticina	38.96	2.00e-76	280.00
IUUC-Pte-104259	Pyrenophora teres	63.93	7.00e-98	351.00
IUUC-Pyt-104752	Pyrenophora triticirepentis	63.56	2.00e-98	353.00
IUUC-Rno-104960	Rattus norvegicus	97.89	0.00e+00	1035.00
IUUC-Sce-106290	Saccharomyces cerevisiae	42.15	8.00e-109	387.00
IUUC-Sja-107772	Schizosaccharomyces japonicus	39.92	2.00e-103	369.00
IUUC-Ssl-108535	Sclerotinia sclerotiorum	48.80	8.00e-97	347.00
IUUC-Sly-110890	Solanum lycopersicum	46.86	9.00e-119	420.00
IUUC-Stu-112144	Solanum tuberosum	45.36	2.00e-112	399.00
IUUC-Sre-115141	Sporisorium reilianum	67.74	2.00e-105	376.00
IUUC-Tru-118735	Takifugu rubripes	84.38	0.00e+00	920.00
IUUC-Tsy-119503	Tarsius syrichta	94.81	0.00e+00	976.00
IUUC-Tni-119880	Tetraodon nigroviridis	85.31	0.00e+00	924.00
IUUC-Tca-121386	Theobroma cacao	46.43	4.00e-119	421.00
IUUC-Tae-123515	Triticum aestivum	46.91	9.00e-119	420.00
IUUC-Tur-126416	Triticum urartu	46.92	1.00e-115	410.00
IUUC-Tbe-127791	Tupaia belangeri	85.65	1.00e-112	399.00
IUUC-Uma-129372	Ustilago maydis	67.74	9.00e-105	374.00
IUUC-Vda-129819	Verticillium dahliae	54.20	4.00e-80	292.00
IUUC-Vpa-130220	Vicugna pacos	98.65	0.00e+00	1033.00
IUUC-Xtr-132954	Xenopus tropicalis	92.13	0.00e+00	1001.00
IUUC-Xma-134119	Xiphophorus maculatus	84.95	0.00e+00	918.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence