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Tag Content
iUUCD ID IUUC-Acl-008205
Ensembl Protein ID CADACLAP00004618
UniProt Accession A1CGS0; SEC13_ASPCL
Genbank Protein ID EAW10075.1
Protein Name Protein transport protein sec13
Genbank Nucleotide ID DS027054
Gene Name ACLA_045400; sec13
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
CADACLAG00004719 CADACLAT00004719 CADACLAP00004618
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.60e-32 108.4 41 73
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf..sd..tllvsGsdDgtikvWD 29
           gH++ v+c+a+  +   t+l+s+s+Dg++ +W+
   Q: 41   GHEGAVWCVAWahPKfgTILASSSYDGKVLIWR 73
           8***********9555599*************8 PP
   
Organism Aspergillus clavatus
Functional Description
(View)

Functional Description


     Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Sec13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
 Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Sec13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
Protein Sequence
(Fasta)
MIHDAGLDYY GRRLATCSSD KTIKIFEIEG ETHRLAETLK GHEGAVWCVA WAHPKFGTIL 60
ASSSYDGKVL IWREQHQSPT SPAAGSAWTK VFDFSLHTAS VNMVSWAPHE SGCLLACASS 120
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Protein Fasta Sequence


>IUUC-Acl-008205|E3,WD_repeat|Aspergillus clavatus
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Nucleotide Sequence
(Fasta)
ATGATTGTAT GTATAGGGAT GCTAAGTCTG CCCTATGCTC TTGCATATAA CGACTATCGA 60
GGCTAATGTC GCCTCTTTCT ACAGCACGAC GCCGGATTGG ACTACTACGG GCGCAGATTA 120
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Nucleotide Fasta Sequence


>IUUC-Acl-008205|E3,WD_repeat|Aspergillus clavatus
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Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0968--Cytoplasmic vesicle
KW-0256--Endoplasmic reticulum
KW-0931--ER-Golgi transport
KW-0472--Membrane
KW-0509--mRNA transport
KW-0906--Nuclear pore complex
KW-0539--Nucleus
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0811--Translocation
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0030127--C:COPII vesicle coat
GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0031080--C:nuclear pore outer ring
GO:0035859--C:Seh1-associated complex
GO:0005198--F:structural molecule activity
GO:0090114--P:COPII-coated vesicle budding
GO:0051028--P:mRNA transport
GO:0031081--P:nuclear pore distribution
GO:0043547--P:positive regulation of GTPase activity
GO:1904263--P:positive regulation of TORC1 signaling
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0015031--P:protein transport
GO:0030433--P:ubiquitin-dependent ERAD pathway
KEGG act:ACLA_045400
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000671 Aegilops tauschii 50.00 3.00e-77 280.00
IUUC-Aml-001832 Ailuropoda melanoleuca 50.83 3.00e-80 289.00
IUUC-Atr-002914 Amborella trichopoda 49.66 1.00e-76 277.00
IUUC-Apl-003992 Anas platyrhynchos 51.17 2.00e-80 290.00
IUUC-Aca-005283 Anolis carolinensis 51.16 3.00e-81 293.00
IUUC-Aly-005654 Arabidopsis lyrata 49.17 1.00e-71 260.00
IUUC-Ath-006816 Arabidopsis thaliana 48.84 3.00e-71 259.00
IUUC-Ago-007827 Ashbya gossypii 56.77 4.00e-95 339.00
IUUC-Afl-008748 Aspergillus flavus 93.90 2.00e-167 579.00
IUUC-Afu-008791 Aspergillus fumigatus 96.61 1.00e-170 590.00
IUUC-Ani-009152 Aspergillus nidulans 92.20 8.00e-165 570.00
IUUC-Ang-009765 Aspergillus niger 97.29 8.00e-172 593.00
IUUC-Aor-009927 Aspergillus oryzae 93.54 5.00e-166 574.00
IUUC-Ate-010248 Aspergillus terreus 95.93 6.00e-171 591.00
IUUC-Ame-011478 Astyanax mexicanus 51.50 1.00e-82 298.00
IUUC-Bgr-012276 Blumeria graminis 70.85 5.00e-124 435.00
IUUC-Bta-012700 Bos taurus 50.50 1.00e-79 288.00
IUUC-Bci-013722 Botrytis cinerea 71.24 4.00e-125 438.00
IUUC-Bdi-014818 Brachypodium distachyon 50.00 4.00e-77 279.00
IUUC-Bol-015779 Brassica oleracea 49.17 3.00e-71 259.00
IUUC-Bra-017934 Brassica rapa 48.84 8.00e-71 258.00
IUUC-Cel-018479 Caenorhabditis elegans 39.53 2.00e-58 217.00
IUUC-Cja-019956 Callithrix jacchus 51.41 6.00e-74 268.00
IUUC-Cfa-020752 Canis familiaris 50.83 4.00e-80 289.00
IUUC-Cpo-021871 Cavia porcellus 51.50 4.00e-81 292.00
IUUC-Cre-022797 Chlamydomonas reinhardtii 49.33 1.00e-75 274.00
IUUC-Csa-023393 Chlorocebus sabaeus 51.50 1.00e-80 291.00
IUUC-Cho-024786 Choloepus hoffmanni 58.00 2.00e-26 111.00
IUUC-Cin-025332 Ciona intestinalis 53.80 7.00e-85 305.00
IUUC-Csv-025926 Ciona savignyi 53.82 8.00e-85 305.00
IUUC-Cgl-026413 Colletotrichum gloeosporioides 71.81 6.00e-117 411.00
IUUC-Cne-027054 Cryptococcus neoformans 50.80 7.00e-77 278.00
IUUC-Cme-027165 Cyanidioschyzon merolae 37.03 9.00e-49 186.00
IUUC-Dre-027782 Danio rerio 52.16 2.00e-82 296.00
IUUC-Dno-029628 Dasypus novemcinctus 50.50 6.00e-80 288.00
IUUC-Dor-030650 Dipodomys ordii 49.14 6.00e-58 215.00
IUUC-Dse-031206 Dothistroma septosporum 66.89 3.00e-115 406.00
IUUC-Dme-031854 Drosophila melanogaster 51.01 3.00e-73 266.00
IUUC-Ete-032618 Echinops telfairi 42.86 1.00e-36 145.00
IUUC-Eca-033268 Equus caballus 50.83 5.00e-80 289.00
IUUC-Fca-035918 Felis catus 50.83 7.00e-80 288.00
IUUC-Fal-037551 Ficedula albicollis 51.16 1.00e-76 277.00
IUUC-Fox-037763 Fusarium oxysporum 71.81 8.00e-126 441.00
IUUC-Fso-038341 Fusarium solani 71.14 1.00e-124 437.00
IUUC-Gmo-038638 Gadus morhua 51.16 8.00e-82 295.00
IUUC-Ggr-039865 Gaeumannomyces graminis 70.90 2.00e-123 433.00
IUUC-Gga-040193 Gallus gallus 51.50 1.00e-81 294.00
IUUC-Gac-041337 Gasterosteus aculeatus 33.55 5.00e-33 133.00
IUUC-Gma-044311 Glycine max 49.83 8.00e-75 271.00
IUUC-Ggo-045252 Gorilla gorilla 51.50 8.00e-81 291.00
IUUC-Hsa-046565 Homo sapiens 51.50 1.00e-80 291.00
IUUC-Hvu-047835 Hordeum vulgare 50.99 2.00e-77 280.00
IUUC-Itr-048587 Ictidomys tridecemlineatus 51.16 3.00e-80 290.00
IUUC-Kpa-049148 Komagataella pastoris 58.86 4.00e-96 342.00
IUUC-Lch-050421 Latimeria chalumnae 52.82 5.00e-84 302.00
IUUC-Lpe-051187 Leersia perrieri 48.17 1.00e-76 280.00
IUUC-Loc-052167 Lepisosteus oculatus 51.16 2.00e-83 300.00
IUUC-Lma-053250 Leptosphaeria maculans 69.59 4.00e-118 415.00
IUUC-Laf-054304 Loxodonta africana 50.83 1.00e-80 291.00
IUUC-Mcc-055519 Macaca mulatta 51.50 1.00e-80 291.00
IUUC-Meu-056439 Macropus eugenii 50.83 3.00e-81 293.00
IUUC-Mor-057241 Magnaporthe oryzae 72.82 4.00e-127 445.00
IUUC-Mpo-057373 Magnaporthe poae 63.18 2.00e-102 362.00
IUUC-Mtr-058412 Medicago truncatula 48.99 1.00e-73 268.00
IUUC-Mla-058966 Melampsora laricipopulina 51.53 5.00e-89 319.00
IUUC-Mga-060066 Meleagris gallopavo 51.17 2.00e-80 290.00
IUUC-Mvi-060290 Microbotryum violaceum 53.73 3.00e-87 316.00
IUUC-Mmr-060717 Microcebus murinus 51.16 1.00e-80 291.00
IUUC-Mdo-062496 Monodelphis domestica 50.50 4.00e-81 292.00
IUUC-Mmu-063490 Mus musculus 51.16 2.00e-80 290.00
IUUC-Mac-064519 Musa acuminata 48.99 1.00e-73 267.00
IUUC-Mpu-066601 Mustela putorius furo 50.83 4.00e-80 289.00
IUUC-Mlu-067501 Myotis lucifugus 50.83 4.00e-80 289.00
IUUC-Nfi-068360 Neosartorya fischeri 96.50 5.00e-147 511.00
IUUC-Ncr-068928 Neurospora crassa 73.15 2.00e-129 453.00
IUUC-Nle-069028 Nomascus leucogenys 51.16 1.00e-80 291.00
IUUC-Opr-070446 Ochotona princeps 50.50 1.00e-78 284.00
IUUC-Ont-071587 Oreochromis niloticus 53.16 2.00e-84 303.00
IUUC-Oan-073211 Ornithorhynchus anatinus 49.83 8.00e-80 288.00
IUUC-Ocu-074306 Oryctolagus cuniculus 51.83 2.00e-81 293.00
IUUC-Oba-075069 Oryza barthii 49.67 5.00e-76 275.00
IUUC-Obr-076667 Oryza brachyantha 50.33 5.00e-77 279.00
IUUC-Ogl-077208 Oryza glaberrima 49.67 5.00e-76 275.00
IUUC-Ogu-078513 Oryza glumaepatula 49.67 5.00e-76 275.00
IUUC-Oin-079094 Oryza indica 49.67 5.00e-76 275.00
IUUC-Olo-080473 Oryza longistaminata 49.67 5.00e-76 275.00
IUUC-Ome-081643 Oryza meridionalis 49.67 5.00e-76 275.00
IUUC-Oni-082589 Oryza nivara 49.67 5.00e-76 275.00
IUUC-Opu-083677 Oryza punctata 49.67 4.00e-76 275.00
IUUC-Oru-084537 Oryza rufipogon 49.67 5.00e-76 275.00
IUUC-Osa-085449 Oryza sativa 49.67 5.00e-76 275.00
IUUC-Ola-087226 Oryzias latipes 52.49 5.00e-84 302.00
IUUC-Olu-087893 Ostreococcus lucimarinus 47.99 6.00e-66 242.00
IUUC-Oga-088837 Otolemur garnettii 50.83 3.00e-80 290.00
IUUC-Oar-089594 Ovis aries 50.83 8.00e-80 288.00
IUUC-Ptr-091132 Pan troglodytes 51.50 8.00e-81 291.00
IUUC-Pan-092013 Papio anubis 33.06 7.00e-26 108.00
IUUC-Psi-093568 Pelodiscus sinensis 51.16 1.00e-81 294.00
IUUC-Pma-094172 Petromyzon marinus 47.44 5.00e-33 131.00
IUUC-Pno-094955 Phaeosphaeria nodorum 69.05 2.00e-116 409.00
IUUC-Ppa-095835 Physcomitrella patens 51.00 1.00e-74 271.00
IUUC-Pfo-096063 Poecilia formosa 53.16 2.00e-84 303.00
IUUC-Pab-098674 Pongo abelii 51.16 9.00e-80 288.00
IUUC-Pop-099402 Populus trichocarpa 47.81 1.00e-71 261.00
IUUC-Pca-100824 Procavia capensis 38.33 5.00e-55 206.00
IUUC-Ppe-101278 Prunus persica 48.17 4.00e-71 259.00
IUUC-Pva-103161 Pteropus vampyrus 46.84 3.00e-72 263.00
IUUC-Pgr-103573 Puccinia graminis 51.40 2.00e-88 317.00
IUUC-Ptt-103700 Puccinia triticina 49.20 3.00e-85 306.00
IUUC-Pte-104267 Pyrenophora teres 67.45 7.00e-113 398.00
IUUC-Pyt-104535 Pyrenophora triticirepentis 65.66 1.00e-107 380.00
IUUC-Rno-104833 Rattus norvegicus 51.16 2.00e-80 290.00
IUUC-Sce-106437 Saccharomyces cerevisiae 59.53 2.00e-93 333.00
IUUC-Sha-106611 Sarcophilus harrisii 50.83 3.00e-81 293.00
IUUC-Sja-107654 Schizosaccharomyces japonicus 54.70 6.00e-89 318.00
IUUC-Spo-108362 Schizosaccharomyces pombe 54.39 1.00e-85 307.00
IUUC-Smo-108797 Selaginella moellendorffii 48.33 5.00e-73 265.00
IUUC-Sit-110132 Setaria italica 50.17 6.00e-77 278.00
IUUC-Sly-111254 Solanum lycopersicum 48.15 5.00e-70 255.00
IUUC-Stu-112591 Solanum tuberosum 48.33 6.00e-71 258.00
IUUC-Sar-113279 Sorex araneus 31.23 1.00e-23 102.00
IUUC-Sbi-114229 Sorghum bicolor 51.50 3.00e-78 283.00
IUUC-Sre-114898 Sporisorium reilianum 49.27 4.00e-85 306.00
IUUC-Ssc-115995 Sus scrofa 52.71 2.00e-36 143.00
IUUC-Tgu-116793 Taeniopygia guttata 51.16 9.00e-77 278.00
IUUC-Tru-117797 Takifugu rubripes 52.16 2.00e-83 300.00
IUUC-Tsy-118913 Tarsius syrichta 31.09 3.00e-21 94.40
IUUC-Tni-120366 Tetraodon nigroviridis 53.49 4.00e-85 306.00
IUUC-Tca-121068 Theobroma cacao 48.81 2.00e-72 264.00
IUUC-Tre-121899 Trichoderma reesei 70.81 3.00e-124 435.00
IUUC-Tvi-122380 Trichoderma virens 71.14 5.00e-125 438.00
IUUC-Tae-123998 Triticum aestivum 50.99 2.00e-78 283.00
IUUC-Tur-126202 Triticum urartu 50.66 1.00e-77 281.00
IUUC-Tme-127181 Tuber melanosporum 60.45 4.00e-105 372.00
IUUC-Ttr-128448 Tursiops truncatus 49.62 3.00e-64 236.00
IUUC-Uma-129661 Ustilago maydis 49.56 2.00e-86 310.00
IUUC-Vda-129666 Verticillium dahliae 71.48 8.00e-121 424.00
IUUC-Vpa-130318 Vicugna pacos 50.83 7.00e-80 288.00
IUUC-Vvi-130868 Vitis vinifera 49.49 1.00e-74 271.00
IUUC-Xtr-131859 Xenopus tropicalis 51.83 1.00e-82 297.00
IUUC-Xma-133898 Xiphophorus maculatus 52.82 5.00e-84 302.00
IUUC-Yli-134559 Yarrowia lipolytica 61.07 4.00e-98 349.00
Created Date 25-Jun-2017

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