iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
RAID2
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.40e-33	112.3	412	449

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvl 35
           gH+ +vt++++  sd t ++++sdD+t+k+W+l +g  
   Q: 412  GHSQEVTSVCWcpSDfTKIATCSDDNTLKIWRLNRGLE 449
           8***********999*****************988866 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MTSVWRGVWR PGLAVAGVGG KTVSRCGGRK RRLRRNLGAI SSAFSSAESS PQDEMLFNSV 60
LRQPQLGVLR NGWSSHYPLQ SLLSGYRCSC NDEHTSYGET GVPVPPFGCT FCTAPSMEHI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACGCTGCGA CGAGAGCCAA TCAGAGAGCA TGACGTCAGT TTGGCGCGGA GTTTGGCGGC 60
CGGGGCTCGC AGTGGCGGGA GTTGGAGGCA AAACCGTGTC GCGCTGTGGA GGGCGCAAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex
GO:0031465--C:Cul4B-RING E3 ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0031572--P:G2 DNA damage checkpoint
GO:0006513--P:protein monoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0009411--P:response to UV
GO:0019985--P:translesion synthesis
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

rno:305073

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002111	Ailuropoda melanoleuca	86.30	0.00e+00	1189.00
IUUC-Atr-003097	Amborella trichopoda	34.63	1.00e-63	237.00
IUUC-Apl-004088	Anas platyrhynchos	60.50	0.00e+00	782.00
IUUC-Aca-004732	Anolis carolinensis	54.84	0.00e+00	669.00
IUUC-Aly-005686	Arabidopsis lyrata	34.17	2.00e-59	223.00
IUUC-Ath-006970	Arabidopsis thaliana	33.97	1.00e-58	221.00
IUUC-Acl-008219	Aspergillus clavatus	24.09	4.00e-23	103.00
IUUC-Afu-008784	Aspergillus fumigatus	25.65	3.00e-23	103.00
IUUC-Ani-009304	Aspergillus nidulans	28.53	5.00e-19	89.70
IUUC-Ang-009842	Aspergillus niger	23.48	5.00e-23	103.00
IUUC-Aor-009883	Aspergillus oryzae	25.22	2.00e-22	101.00
IUUC-Ate-010454	Aspergillus terreus	27.92	6.00e-22	98.60
IUUC-Ame-010949	Astyanax mexicanus	65.06	3.00e-162	565.00
IUUC-Bta-012333	Bos taurus	86.30	0.00e+00	1176.00
IUUC-Bci-013733	Botrytis cinerea	26.06	3.00e-21	97.10
IUUC-Bdi-014494	Brachypodium distachyon	33.05	6.00e-57	214.00
IUUC-Bol-015301	Brassica oleracea	34.90	2.00e-58	220.00
IUUC-Bra-017384	Brassica rapa	34.17	2.00e-59	223.00
IUUC-Cel-018498	Caenorhabditis elegans	27.60	2.00e-31	130.00
IUUC-Cja-019534	Callithrix jacchus	88.40	0.00e+00	1235.00
IUUC-Cfa-020847	Canis familiaris	86.58	0.00e+00	1171.00
IUUC-Cpo-021695	Cavia porcellus	85.97	0.00e+00	1148.00
IUUC-Cre-022762	Chlamydomonas reinhardtii	28.75	3.00e-40	161.00
IUUC-Csa-023748	Chlorocebus sabaeus	88.36	0.00e+00	1215.00
IUUC-Cho-024445	Choloepus hoffmanni	81.39	3.00e-175	608.00
IUUC-Cgl-026664	Colletotrichum gloeosporioides	24.36	1.00e-18	88.20
IUUC-Cne-027008	Cryptococcus neoformans	24.33	2.00e-12	69.30
IUUC-Dre-027536	Danio rerio	46.42	9.00e-164	570.00
IUUC-Dno-030035	Dasypus novemcinctus	78.25	0.00e+00	1093.00
IUUC-Dor-030814	Dipodomys ordii	75.58	2.00e-132	466.00
IUUC-Dse-031354	Dothistroma septosporum	24.00	1.00e-27	117.00
IUUC-Dme-031691	Drosophila melanogaster	41.87	2.00e-81	297.00
IUUC-Ete-032814	Echinops telfairi	76.13	0.00e+00	764.00
IUUC-Eca-033332	Equus caballus	86.85	0.00e+00	1171.00
IUUC-Fca-035571	Felis catus	86.44	0.00e+00	1165.00
IUUC-Fal-037421	Ficedula albicollis	59.36	0.00e+00	764.00
IUUC-Fox-038069	Fusarium oxysporum	22.94	7.00e-16	79.00
IUUC-Gmo-039365	Gadus morhua	64.32	1.00e-155	543.00
IUUC-Ggr-039904	Gaeumannomyces graminis	24.65	8.00e-16	79.30
IUUC-Gga-041153	Gallus gallus	60.08	0.00e+00	777.00
IUUC-Gac-041984	Gasterosteus aculeatus	60.00	4.00e-158	551.00
IUUC-Gma-042679	Glycine max	36.00	9.00e-60	224.00
IUUC-Ggo-044419	Gorilla gorilla	87.55	0.00e+00	1192.00
IUUC-Hsa-045862	Homo sapiens	87.81	0.00e+00	1200.00
IUUC-Hvu-047728	Hordeum vulgare	33.79	3.00e-61	229.00
IUUC-Itr-048786	Ictidomys tridecemlineatus	88.77	0.00e+00	1236.00
IUUC-Lch-050616	Latimeria chalumnae	53.81	0.00e+00	674.00
IUUC-Lpe-051222	Leersia perrieri	34.66	2.00e-58	219.00
IUUC-Loc-052564	Lepisosteus oculatus	52.14	7.00e-171	593.00
IUUC-Lma-053098	Leptosphaeria maculans	24.66	5.00e-25	109.00
IUUC-Laf-053892	Loxodonta africana	83.88	0.00e+00	1103.00
IUUC-Mcc-055854	Macaca mulatta	88.22	0.00e+00	1212.00
IUUC-Mor-057144	Magnaporthe oryzae	28.21	6.00e-16	79.70
IUUC-Mtr-058510	Medicago truncatula	34.45	9.00e-55	207.00
IUUC-Mla-058823	Melampsora laricipopulina	26.05	6.00e-21	95.90
IUUC-Mga-060128	Meleagris gallopavo	59.34	0.00e+00	782.00
IUUC-Mvi-060475	Microbotryum violaceum	31.52	2.00e-43	171.00
IUUC-Mmr-061331	Microcebus murinus	86.99	0.00e+00	1173.00
IUUC-Mdo-063020	Monodelphis domestica	69.42	0.00e+00	967.00
IUUC-Mmu-063713	Mus musculus	93.15	0.00e+00	1212.00
IUUC-Mac-064653	Musa acuminata	33.06	1.00e-57	217.00
IUUC-Mpu-066490	Mustela putorius furo	86.30	0.00e+00	1163.00
IUUC-Mlu-067900	Myotis lucifugus	85.75	0.00e+00	1138.00
IUUC-Nfi-068433	Neosartorya fischeri	24.10	3.00e-24	107.00
IUUC-Ncr-068776	Neurospora crassa	27.82	2.00e-27	117.00
IUUC-Nle-069675	Nomascus leucogenys	83.99	0.00e+00	1116.00
IUUC-Opr-070769	Ochotona princeps	59.73	9.00e-124	437.00
IUUC-Ont-071441	Oreochromis niloticus	66.14	8.00e-154	537.00
IUUC-Oan-072757	Ornithorhynchus anatinus	65.63	0.00e+00	863.00
IUUC-Ocu-074670	Oryctolagus cuniculus	87.81	0.00e+00	1197.00
IUUC-Oba-075844	Oryza barthii	33.70	4.00e-57	215.00
IUUC-Obr-076625	Oryza brachyantha	36.41	2.00e-61	230.00
IUUC-Ogl-077771	Oryza glaberrima	33.70	4.00e-57	215.00
IUUC-Ogu-078475	Oryza glumaepatula	32.59	4.00e-49	189.00
IUUC-Oin-079958	Oryza indica	33.70	4.00e-57	215.00
IUUC-Olo-080311	Oryza longistaminata	32.89	1.00e-45	177.00
IUUC-Ome-081985	Oryza meridionalis	32.87	5.00e-56	211.00
IUUC-Oni-082921	Oryza nivara	33.70	4.00e-57	215.00
IUUC-Opu-083174	Oryza punctata	32.32	4.00e-55	209.00
IUUC-Oru-084338	Oryza rufipogon	33.70	5.00e-57	215.00
IUUC-Osa-085609	Oryza sativa	41.11	4.00e-19	87.80
IUUC-Olu-087907	Ostreococcus lucimarinus	27.84	4.00e-29	122.00
IUUC-Oga-088358	Otolemur garnettii	87.12	0.00e+00	1225.00
IUUC-Oar-089994	Ovis aries	86.03	0.00e+00	1175.00
IUUC-Ptr-091338	Pan troglodytes	88.08	0.00e+00	1234.00
IUUC-Pan-091759	Papio anubis	88.24	0.00e+00	1211.00
IUUC-Psi-093211	Pelodiscus sinensis	58.64	0.00e+00	695.00
IUUC-Pma-094588	Petromyzon marinus	58.17	2.00e-97	348.00
IUUC-Pno-094964	Phaeosphaeria nodorum	25.60	9.00e-27	115.00
IUUC-Ppa-095159	Physcomitrella patens	37.05	2.00e-62	233.00
IUUC-Pfo-096592	Poecilia formosa	57.86	2.00e-138	486.00
IUUC-Pab-098597	Pongo abelii	71.82	0.00e+00	896.00
IUUC-Pop-099255	Populus trichocarpa	36.89	2.00e-63	236.00
IUUC-Pca-100593	Procavia capensis	67.66	0.00e+00	827.00
IUUC-Ppe-101333	Prunus persica	34.96	8.00e-57	214.00
IUUC-Pva-102283	Pteropus vampyrus	82.47	0.00e+00	1100.00
IUUC-Pgr-103383	Puccinia graminis	27.68	1.00e-22	101.00
IUUC-Ptt-103974	Puccinia triticina	27.52	3.00e-20	93.20
IUUC-Pte-104329	Pyrenophora teres	24.65	3.00e-25	110.00
IUUC-Pyt-104424	Pyrenophora triticirepentis	27.94	5.00e-25	109.00
IUUC-Sha-106891	Sarcophilus harrisii	65.90	0.00e+00	847.00
IUUC-Sja-107723	Schizosaccharomyces japonicus	26.85	2.00e-25	110.00
IUUC-Spo-108060	Schizosaccharomyces pombe	25.70	2.00e-19	90.50
IUUC-Ssl-108481	Sclerotinia sclerotiorum	27.74	3.00e-19	90.50
IUUC-Sit-109862	Setaria italica	32.77	1.00e-55	211.00
IUUC-Sly-111468	Solanum lycopersicum	34.07	6.00e-60	225.00
IUUC-Stu-112346	Solanum tuberosum	34.18	2.00e-57	216.00
IUUC-Sar-113734	Sorex araneus	77.73	3.00e-100	359.00
IUUC-Sbi-114076	Sorghum bicolor	32.87	7.00e-57	214.00
IUUC-Ssc-115561	Sus scrofa	85.23	0.00e+00	1154.00
IUUC-Tgu-117011	Taeniopygia guttata	60.59	0.00e+00	759.00
IUUC-Tru-118411	Takifugu rubripes	59.01	9.00e-151	527.00
IUUC-Tsy-119367	Tarsius syrichta	78.36	0.00e+00	1010.00
IUUC-Tni-120301	Tetraodon nigroviridis	59.43	2.00e-147	516.00
IUUC-Tca-121265	Theobroma cacao	35.54	4.00e-60	225.00
IUUC-Tre-121997	Trichoderma reesei	25.10	1.00e-18	88.20
IUUC-Tvi-122292	Trichoderma virens	25.15	8.00e-20	92.40
IUUC-Tae-123660	Triticum aestivum	32.22	6.00e-59	221.00
IUUC-Tur-126794	Triticum urartu	30.85	9.00e-43	167.00
IUUC-Tme-127090	Tuber melanosporum	27.48	2.00e-18	86.70
IUUC-Tbe-127646	Tupaia belangeri	85.95	0.00e+00	760.00
IUUC-Ttr-128171	Tursiops truncatus	85.89	0.00e+00	1181.00
IUUC-Uma-129525	Ustilago maydis	24.93	5.00e-18	86.70
IUUC-Vda-129871	Verticillium dahliae	24.82	3.00e-20	93.60
IUUC-Vpa-130554	Vicugna pacos	74.17	2.00e-134	473.00
IUUC-Vvi-131698	Vitis vinifera	35.83	3.00e-61	229.00
IUUC-Xtr-131962	Xenopus tropicalis	55.62	0.00e+00	731.00
IUUC-Xma-133803	Xiphophorus maculatus	59.76	8.00e-150	523.00
IUUC-Zma-135693	Zea mays	31.50	2.00e-54	206.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence