iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tme-127004

Ensembl Protein ID

CAZ80330

UniProt Accession

D5G737; D5G737_TUBMM

Genbank Protein ID

CAZ80330.1

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

FN430021

Gene Name

GSTUM_00002325001

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GSTUM_00002325001	CAZ80330	CAZ80330

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	5.20e-79	264.7	1201	1544

Active Site

Position(s)	Description	Evidence
1513	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklll 101
           +d+kk l++ef gE+g+d+gG+++e++ l+++++++p++g+f+y+++++++ + np+s     e  + F ++G+l g+a++++ +ld+ l++ ++k+ll
   Q: 1201 DDIKKGLRIEFIGEDGVDAGGLKKEWFLLVARDVFDPSYGMFVYDDDSQYC-YFNPNSL----ESSEEFFLVGVLFGLAIYNSTILDVALPPYIFKKLL 1294
           7899*****************************************999988.6699998....5678888****************************8 PP
   S: 102  gk...............klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkeg 185
           +                  +ledl+ + p l++ l +++e  e d+e + ++  f +++e +g++  + L+p+Gen pVt +N++e+v+l+++y l+++
   Q: 1295 HFtvphslavssirpplHHTLEDLAVFRPSLAHGLRQLLEF-EGDVEST-FCRDFVAETERFGQVIRVPLCPNGENRPVTSSNRREFVDLYLNYLLNSS 1391
           886777777777777666899******************99.6788886.************************************************* PP
   S: 186  ikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketky....kggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGf 279
           +++q+e f++Gf++v+  + l+lF++ee+elli G+ e +dv++lk+ + y     g+  e++p ++wFw+++e+++ +e++++L F+Tgs+r+P+ G 
   Q: 1392 VAKQFEPFKRGFYTVCGGNALALFRPEEIELLIRGSdEALDVSALKAVAIYdgwgGGNPAENDPIVKWFWNFFEKITPKEQRMLLSFITGSDRIPAMGA 1490
           ************************************999************77765667899************************************* PP
   S: 280  aelkprlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
            +l  +++++ +  + +r+P + TCfn+++L++Y+  e+l+  L  A++e++gF+l
   Q: 1491 TNLIIKVVCLGQ--DSNRFPVARTCFNQICLWRYKRREKLEALLWRAVTESEGFGL 1544
           ****77666666..88**************************************98 PP

Organism

Tuber melanosporum

Protein Sequence
(Fasta)

MSPPLLPSSH SLSSHPRIPS SAIPPHSRKT TISAWGHKYV PTPLHPAAQV LTTHQESWDT 60
LADEALDLLT LLRIPSPPAS PTSPQKDLYT TPKEHHDTHP TLSTLWQRVD TVPAWVDWEQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGCCAC CACTACTACC ATCTTCACAT TCCCTCTCCT CGCATCCCCG CATCCCCTCC 60
AGCGCAATCC CCCCCCACTC TCGCAAAACG ACAATCAGCG CCTGGGGCCA CAAATATGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway

Interpro

IPR018713--DUF2236
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF09995--DUF2236
PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

tml:GSTUM_00002325001

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	33.11	5.00e-106	376.00
IUUC-Atr-003144	Amborella trichopoda	40.43	6.00e-88	315.00
IUUC-Apl-003589	Anas platyrhynchos	32.46	8.00e-98	349.00
IUUC-Aca-004350	Anolis carolinensis	41.27	8.00e-99	352.00
IUUC-Ago-007908	Ashbya gossypii	31.87	4.00e-95	340.00
IUUC-Acl-008288	Aspergillus clavatus	49.01	0.00e+00	811.00
IUUC-Afl-008402	Aspergillus flavus	53.90	0.00e+00	731.00
IUUC-Afu-008762	Aspergillus fumigatus	50.05	0.00e+00	836.00
IUUC-Ani-009176	Aspergillus nidulans	42.09	0.00e+00	762.00
IUUC-Ang-009791	Aspergillus niger	45.44	0.00e+00	836.00
IUUC-Aor-009921	Aspergillus oryzae	57.77	0.00e+00	708.00
IUUC-Ate-010295	Aspergillus terreus	50.95	0.00e+00	807.00
IUUC-Ame-010768	Astyanax mexicanus	35.98	5.00e-82	297.00
IUUC-Bgr-011981	Blumeria graminis	46.24	0.00e+00	865.00
IUUC-Bta-012945	Bos taurus	41.92	3.00e-100	357.00
IUUC-Bci-013697	Botrytis cinerea	43.71	0.00e+00	828.00
IUUC-Cel-018150	Caenorhabditis elegans	32.31	2.00e-50	192.00
IUUC-Cja-019263	Callithrix jacchus	41.48	5.00e-98	350.00
IUUC-Cfa-020486	Canis familiaris	33.01	5.00e-106	376.00
IUUC-Cpo-021755	Cavia porcellus	34.71	3.00e-105	374.00
IUUC-Cre-022790	Chlamydomonas reinhardtii	40.71	4.00e-58	216.00
IUUC-Csa-023814	Chlorocebus sabaeus	41.22	2.00e-86	311.00
IUUC-Cho-025059	Choloepus hoffmanni	31.60	4.00e-72	264.00
IUUC-Cin-025643	Ciona intestinalis	28.68	1.00e-70	259.00
IUUC-Csv-026282	Ciona savignyi	30.76	1.00e-61	229.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	47.43	0.00e+00	752.00
IUUC-Cme-027151	Cyanidioschyzon merolae	39.23	1.00e-80	293.00
IUUC-Dre-028551	Danio rerio	41.56	5.00e-97	346.00
IUUC-Dno-029497	Dasypus novemcinctus	41.72	8.00e-99	352.00
IUUC-Dor-030158	Dipodomys ordii	34.52	5.00e-73	267.00
IUUC-Dse-031239	Dothistroma septosporum	44.94	0.00e+00	742.00
IUUC-Dme-032035	Drosophila melanogaster	33.12	4.00e-71	261.00
IUUC-Ete-032902	Echinops telfairi	32.57	6.00e-94	336.00
IUUC-Eca-033678	Equus caballus	32.87	3.00e-106	377.00
IUUC-Eeu-035109	Erinaceus europaeus	32.31	1.00e-72	266.00
IUUC-Fca-035590	Felis catus	33.15	1.00e-106	379.00
IUUC-Fal-037123	Ficedula albicollis	35.14	9.00e-90	322.00
IUUC-Fox-037941	Fusarium oxysporum	42.48	0.00e+00	810.00
IUUC-Fso-038388	Fusarium solani	42.04	0.00e+00	789.00
IUUC-Gmo-039553	Gadus morhua	41.72	4.00e-84	303.00
IUUC-Ggr-040110	Gaeumannomyces graminis	43.83	0.00e+00	723.00
IUUC-Gga-040406	Gallus gallus	35.71	3.00e-100	357.00
IUUC-Gac-042141	Gasterosteus aculeatus	32.27	6.00e-100	356.00
IUUC-Ggo-045504	Gorilla gorilla	41.27	8.00e-98	349.00
IUUC-Hsa-045786	Homo sapiens	41.27	8.00e-98	349.00
IUUC-Itr-048050	Ictidomys tridecemlineatus	37.82	2.00e-80	291.00
IUUC-Kpa-049152	Komagataella pastoris	33.11	2.00e-94	338.00
IUUC-Lch-049824	Latimeria chalumnae	41.28	4.00e-83	300.00
IUUC-Loc-052173	Lepisosteus oculatus	32.87	5.00e-106	376.00
IUUC-Laf-054017	Loxodonta africana	41.70	3.00e-99	354.00
IUUC-Mcc-055713	Macaca mulatta	41.48	3.00e-98	350.00
IUUC-Meu-056061	Macropus eugenii	33.12	8.00e-81	293.00
IUUC-Mor-057045	Magnaporthe oryzae	44.07	0.00e+00	806.00
IUUC-Mla-059187	Melampsora laricipopulina	44.55	3.00e-98	349.00
IUUC-Mga-059884	Meleagris gallopavo	41.86	2.00e-92	331.00
IUUC-Mmr-061344	Microcebus murinus	32.60	5.00e-106	376.00
IUUC-Mdo-062653	Monodelphis domestica	41.76	2.00e-98	351.00
IUUC-Mmu-063775	Mus musculus	42.27	3.00e-101	360.00
IUUC-Mpu-066069	Mustela putorius furo	32.60	7.00e-106	375.00
IUUC-Mlu-067925	Myotis lucifugus	42.14	2.00e-101	361.00
IUUC-Nfi-068439	Neosartorya fischeri	45.48	0.00e+00	839.00
IUUC-Ncr-068903	Neurospora crassa	43.91	0.00e+00	824.00
IUUC-Nle-070046	Nomascus leucogenys	32.56	6.00e-103	366.00
IUUC-Opr-070891	Ochotona princeps	35.07	8.00e-58	217.00
IUUC-Ont-072126	Oreochromis niloticus	34.77	4.00e-104	370.00
IUUC-Oan-072933	Ornithorhynchus anatinus	41.85	4.00e-99	353.00
IUUC-Ocu-073800	Oryctolagus cuniculus	41.48	1.00e-98	352.00
IUUC-Ola-086988	Oryzias latipes	34.87	3.00e-102	364.00
IUUC-Oga-088117	Otolemur garnettii	41.70	7.00e-99	352.00
IUUC-Oar-089371	Ovis aries	41.92	6.00e-100	356.00
IUUC-Ptr-090551	Pan troglodytes	41.27	8.00e-98	349.00
IUUC-Pan-092067	Papio anubis	41.48	3.00e-98	351.00
IUUC-Psi-092963	Pelodiscus sinensis	41.32	1.00e-96	345.00
IUUC-Pma-094643	Petromyzon marinus	33.72	1.00e-82	298.00
IUUC-Ppa-095354	Physcomitrella patens	38.74	2.00e-88	318.00
IUUC-Pfo-096562	Poecilia formosa	35.08	1.00e-103	368.00
IUUC-Pab-098680	Pongo abelii	41.48	2.00e-98	351.00
IUUC-Pca-100869	Procavia capensis	32.47	7.00e-80	290.00
IUUC-Pva-102219	Pteropus vampyrus	39.27	1.00e-78	285.00
IUUC-Pgr-103315	Puccinia graminis	36.74	6.00e-108	383.00
IUUC-Ptt-103736	Puccinia triticina	43.58	1.00e-104	372.00
IUUC-Rno-105270	Rattus norvegicus	42.14	2.00e-101	361.00
IUUC-Sce-106306	Saccharomyces cerevisiae	31.22	2.00e-85	308.00
IUUC-Sha-106819	Sarcophilus harrisii	34.96	2.00e-106	377.00
IUUC-Sja-107974	Schizosaccharomyces japonicus	41.21	1.00e-69	255.00
IUUC-Spo-108271	Schizosaccharomyces pombe	39.73	1.00e-123	435.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	44.68	0.00e+00	874.00
IUUC-Smo-108858	Selaginella moellendorffii	42.04	4.00e-87	313.00
IUUC-Sar-113134	Sorex araneus	37.14	2.00e-82	298.00
IUUC-Ssc-115441	Sus scrofa	42.05	4.00e-100	357.00
IUUC-Tgu-117166	Taeniopygia guttata	36.39	1.00e-97	348.00
IUUC-Tru-118368	Takifugu rubripes	33.33	3.00e-82	297.00
IUUC-Tsy-118898	Tarsius syrichta	36.15	1.00e-76	278.00
IUUC-Tni-120143	Tetraodon nigroviridis	33.50	5.00e-83	300.00
IUUC-Tre-122108	Trichoderma reesei	42.17	0.00e+00	769.00
IUUC-Tvi-122644	Trichoderma virens	41.55	0.00e+00	781.00
IUUC-Tbe-127640	Tupaia belangeri	36.97	5.00e-65	241.00
IUUC-Ttr-128352	Tursiops truncatus	39.96	1.00e-91	328.00
IUUC-Vda-129969	Verticillium dahliae	45.62	0.00e+00	730.00
IUUC-Vpa-130448	Vicugna pacos	34.78	8.00e-75	273.00
IUUC-Xtr-132594	Xenopus tropicalis	40.18	2.00e-87	314.00
IUUC-Xma-134157	Xiphophorus maculatus	34.55	2.00e-92	331.00
IUUC-Yli-134470	Yarrowia lipolytica	40.26	1.00e-101	362.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence