iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071377

Ensembl Protein ID

ENSONIP00000006137.1

UniProt Accession

I3JB97; I3JB97_ORENI

Genbank Protein ID

ENSONIP00000006137

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01012240

Gene Name

prp19; prpf19

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000004880.1	ENSONIT00000006141.1	ENSONIP00000006137.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-32	111.1	391	424
E3 activity/RING/U-box	6.50e-15	55.4	3	61
UBD/Beta-Prp	3.20e-52	178.0	233	462

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrt 32
           gH+++vt++af  ++ +l++G+ D ++k+WDlr+
   Q: 391  GHSGPVTSIAFseNGYYLATGAQDSSLKLWDLRK 424
           8**********976699**************986 PP

E3 activity/RING/U-box

   S: 6    flCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltlrrl 64
           ++C+Is+e++++P+v+p s+++++r+ Iek++a++g+ +P+++qpl+ee+lv+ ++ + +
   Q: 3    LVCAISNEVPEHPCVSPvSNQVFERRLIEKYIAENGT-DPMNGQPLSEEQLVDIKVAHPI 61
           79**********************************9.**************99987765 PP

UBD/Beta-Prp

   S: 20   pdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdk 108
            d++ ++tg++d+ + v+d  +++ +++l+gh+++vt+v ++p++++  ++s D ti+vw++  g cv+++++he+ v+ ls++++gd+
   Q: 233  SDTNKVLTGGADKNVVVFDKNEEQIVATLKGHTKKVTSVIYHPSQSVVFSASPDTTIRVWSVTGGNCVQVVRAHEAGVTGLSLHATGDY 321
           68899************************************************************************************ PP
   S: 109  lvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelv 196
           l+s s+d++    d++tg +l + t++    + +c+++hpdg ++ +G++D+++++Wdlk  + +  + g h ++v+s++f++ng +l+
   Q: 322  LLSSSEDQYWAFSDIQTGRVLTKvTDESAGCALTCAQFHPDGLIFGTGTADSQIKIWDLKERTNVANFPG-HSGPVTSIAFSENGYYLA 409
           *********************997777777899************************************9.****************** PP
   S: 197  sgsldgtvklwdlqtgecvrtlng.htdnvksvrfspnderlvsgssDgsiri 248
           +g++d+++klwdl++ +  +t +   +  vks+ f++ +++l++g+sD  ++i
   Q: 410  TGAQDSSLKLWDLRKLKNFKTITLdNNYEVKSLVFDQSGTYLAVGGSDIRVYI 462
           **************888888777537799*******************88877 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MALVCAISNE VPEHPCVSPV SNQVFERRLI EKYIAENGTD PMNGQPLSEE QLVDIKVAHP 60
IRPKAPSATS IPAILKSLQD EWDAVMLHSF TLRQQLQTTR QELSHALYQH DAACRVIARL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATTTAGGAA GCTGGAAAGT GGTCAAATGT TCTCCTCGGC GCAGTGACGG TAGGTGGCAG 60
AGTTTGGGAC ATTGAAGCTA ACTCAAAGCG TAGAAGAAGA GTGTTCGTTG TAGCGGCAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013915--Pre-mRNA_splic_Prp19
IPR000772--Ricin_B_lectin
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50231--RICIN_B_LECTIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08606--Prp19
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0043518--P:negative regulation of DNA damage response, signal transduction by p53 class mediator

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000488	Aegilops tauschii	40.19	9.00e-99	355.00
IUUC-Aml-001230	Ailuropoda melanoleuca	82.80	0.00e+00	858.00
IUUC-Atr-002594	Amborella trichopoda	44.34	1.00e-118	420.00
IUUC-Apl-003686	Anas platyrhynchos	77.10	0.00e+00	659.00
IUUC-Aca-005272	Anolis carolinensis	85.54	0.00e+00	904.00
IUUC-Aly-005586	Arabidopsis lyrata	44.02	3.00e-118	419.00
IUUC-Ath-007696	Arabidopsis thaliana	43.74	7.00e-116	410.00
IUUC-Acl-008335	Aspergillus clavatus	37.20	6.00e-69	254.00
IUUC-Afl-008527	Aspergillus flavus	38.40	1.00e-73	270.00
IUUC-Afu-008957	Aspergillus fumigatus	38.95	5.00e-80	291.00
IUUC-Ani-009280	Aspergillus nidulans	39.04	2.00e-68	253.00
IUUC-Ang-009746	Aspergillus niger	37.55	3.00e-68	253.00
IUUC-Aor-009905	Aspergillus oryzae	38.19	3.00e-77	282.00
IUUC-Ate-010412	Aspergillus terreus	37.26	2.00e-64	240.00
IUUC-Ame-011561	Astyanax mexicanus	91.29	9.00e-117	412.00
IUUC-Bgr-012283	Blumeria graminis	33.12	1.00e-57	217.00
IUUC-Bta-013242	Bos taurus	84.95	0.00e+00	905.00
IUUC-Bci-013901	Botrytis cinerea	34.99	3.00e-69	256.00
IUUC-Bdi-014277	Brachypodium distachyon	44.72	1.00e-124	440.00
IUUC-Bol-016207	Brassica oleracea	45.16	1.00e-118	420.00
IUUC-Bra-017650	Brassica rapa	45.16	2.00e-120	426.00
IUUC-Cel-018271	Caenorhabditis elegans	52.66	1.00e-154	540.00
IUUC-Cja-019879	Callithrix jacchus	84.58	0.00e+00	897.00
IUUC-Cfa-020175	Canis familiaris	84.95	0.00e+00	903.00
IUUC-Cpo-022379	Cavia porcellus	85.15	0.00e+00	904.00
IUUC-Cre-022993	Chlamydomonas reinhardtii	40.47	8.00e-100	357.00
IUUC-Csa-023500	Chlorocebus sabaeus	84.95	0.00e+00	904.00
IUUC-Cho-025065	Choloepus hoffmanni	75.00	2.00e-130	458.00
IUUC-Cin-025699	Ciona intestinalis	68.93	7.00e-176	610.00
IUUC-Csv-026128	Ciona savignyi	66.35	0.00e+00	696.00
IUUC-Cgl-026507	Colletotrichum gloeosporioides	34.46	4.00e-65	242.00
IUUC-Cne-026860	Cryptococcus neoformans	37.11	3.00e-92	332.00
IUUC-Dre-028187	Danio rerio	93.66	0.00e+00	925.00
IUUC-Dno-029453	Dasypus novemcinctus	84.95	0.00e+00	903.00
IUUC-Dor-030150	Dipodomys ordii	84.94	1.00e-112	400.00
IUUC-Dse-031220	Dothistroma septosporum	31.72	5.00e-57	215.00
IUUC-Dme-031906	Drosophila melanogaster	66.86	0.00e+00	669.00
IUUC-Ete-033035	Echinops telfairi	74.06	0.00e+00	758.00
IUUC-Eca-033478	Equus caballus	84.75	0.00e+00	902.00
IUUC-Eeu-034974	Erinaceus europaeus	83.28	3.00e-173	601.00
IUUC-Fca-036194	Felis catus	84.69	0.00e+00	896.00
IUUC-Fal-037417	Ficedula albicollis	84.75	0.00e+00	899.00
IUUC-Fox-037922	Fusarium oxysporum	33.13	3.00e-63	236.00
IUUC-Fso-038256	Fusarium solani	34.67	2.00e-67	249.00
IUUC-Gmo-038713	Gadus morhua	95.84	0.00e+00	951.00
IUUC-Ggr-039854	Gaeumannomyces graminis	32.55	6.00e-53	202.00
IUUC-Gga-041143	Gallus gallus	84.95	0.00e+00	900.00
IUUC-Gac-042129	Gasterosteus aculeatus	96.04	0.00e+00	974.00
IUUC-Gma-044273	Glycine max	44.72	6.00e-121	427.00
IUUC-Ggo-045262	Gorilla gorilla	84.95	0.00e+00	904.00
IUUC-Hsa-046036	Homo sapiens	84.95	0.00e+00	904.00
IUUC-Hvu-047442	Hordeum vulgare	44.79	1.00e-66	246.00
IUUC-Itr-048169	Ictidomys tridecemlineatus	84.16	0.00e+00	868.00
IUUC-Lch-050105	Latimeria chalumnae	84.95	0.00e+00	897.00
IUUC-Lpe-050976	Leersia perrieri	45.07	8.00e-121	427.00
IUUC-Loc-052042	Lepisosteus oculatus	80.21	0.00e+00	706.00
IUUC-Lma-053143	Leptosphaeria maculans	34.39	9.00e-68	252.00
IUUC-Laf-053451	Loxodonta africana	81.80	0.00e+00	891.00
IUUC-Mcc-055786	Macaca mulatta	84.95	0.00e+00	904.00
IUUC-Meu-056161	Macropus eugenii	84.65	2.00e-125	442.00
IUUC-Mor-057215	Magnaporthe oryzae	33.66	1.00e-54	207.00
IUUC-Mpo-057419	Magnaporthe poae	31.96	1.00e-50	194.00
IUUC-Mtr-057756	Medicago truncatula	43.97	1.00e-115	410.00
IUUC-Mla-059085	Melampsora laricipopulina	38.36	5.00e-88	318.00
IUUC-Mga-060158	Meleagris gallopavo	80.20	0.00e+00	803.00
IUUC-Mvi-060441	Microbotryum violaceum	39.02	1.00e-81	297.00
IUUC-Mmr-061085	Microcebus murinus	84.95	0.00e+00	904.00
IUUC-Mdo-061804	Monodelphis domestica	84.95	0.00e+00	904.00
IUUC-Mmu-063608	Mus musculus	81.87	0.00e+00	890.00
IUUC-Mac-064972	Musa acuminata	44.98	8.00e-119	421.00
IUUC-Mpu-065700	Mustela putorius furo	84.95	0.00e+00	905.00
IUUC-Mlu-068223	Myotis lucifugus	82.31	0.00e+00	893.00
IUUC-Nfi-068504	Neosartorya fischeri	38.53	6.00e-79	288.00
IUUC-Ncr-068729	Neurospora crassa	35.13	2.00e-62	233.00
IUUC-Nle-069754	Nomascus leucogenys	84.95	0.00e+00	904.00
IUUC-Opr-070621	Ochotona princeps	82.73	0.00e+00	855.00
IUUC-Oan-073498	Ornithorhynchus anatinus	62.58	1.00e-105	375.00
IUUC-Ocu-074182	Oryctolagus cuniculus	81.56	0.00e+00	891.00
IUUC-Oba-075509	Oryza barthii	44.91	6.00e-124	437.00
IUUC-Obr-076480	Oryza brachyantha	45.30	5.00e-124	438.00
IUUC-Ogl-077052	Oryza glaberrima	44.91	6.00e-124	437.00
IUUC-Ogu-078919	Oryza glumaepatula	44.91	5.00e-124	437.00
IUUC-Oin-079357	Oryza indica	43.63	1.00e-116	413.00
IUUC-Olo-080376	Oryza longistaminata	44.26	3.00e-111	395.00
IUUC-Ome-081973	Oryza meridionalis	44.06	5.00e-111	394.00
IUUC-Oni-082849	Oryza nivara	44.91	3.00e-124	438.00
IUUC-Opu-083243	Oryza punctata	44.72	4.00e-123	435.00
IUUC-Oru-084613	Oryza rufipogon	44.91	9.00e-124	437.00
IUUC-Osa-085407	Oryza sativa	44.89	2.00e-123	436.00
IUUC-Ola-086566	Oryzias latipes	95.49	0.00e+00	941.00
IUUC-Olu-087757	Ostreococcus lucimarinus	38.05	1.00e-90	327.00
IUUC-Oga-089010	Otolemur garnettii	82.38	0.00e+00	860.00
IUUC-Oar-089638	Ovis aries	84.95	0.00e+00	905.00
IUUC-Ptr-091141	Pan troglodytes	84.95	0.00e+00	904.00
IUUC-Pan-092662	Papio anubis	84.95	0.00e+00	904.00
IUUC-Psi-093777	Pelodiscus sinensis	83.81	0.00e+00	733.00
IUUC-Pno-095115	Phaeosphaeria nodorum	35.44	2.00e-69	256.00
IUUC-Ppa-095841	Physcomitrella patens	45.92	4.00e-123	435.00
IUUC-Pfo-096390	Poecilia formosa	95.84	0.00e+00	952.00
IUUC-Pab-098250	Pongo abelii	85.32	0.00e+00	852.00
IUUC-Pop-099854	Populus trichocarpa	44.98	3.00e-120	425.00
IUUC-Pca-100553	Procavia capensis	84.36	0.00e+00	894.00
IUUC-Ppe-101383	Prunus persica	44.59	5.00e-116	411.00
IUUC-Pva-102189	Pteropus vampyrus	84.95	0.00e+00	904.00
IUUC-Pgr-103304	Puccinia graminis	36.47	7.00e-85	308.00
IUUC-Ptt-103984	Puccinia triticina	36.84	4.00e-89	322.00
IUUC-Pte-104385	Pyrenophora teres	33.97	1.00e-72	267.00
IUUC-Pyt-104697	Pyrenophora triticirepentis	33.97	8.00e-73	267.00
IUUC-Rno-105581	Rattus norvegicus	84.95	0.00e+00	904.00
IUUC-Sha-107071	Sarcophilus harrisii	81.40	0.00e+00	890.00
IUUC-Sja-107697	Schizosaccharomyces japonicus	29.89	9.00e-37	148.00
IUUC-Spo-108315	Schizosaccharomyces pombe	30.94	6.00e-43	168.00
IUUC-Ssl-108628	Sclerotinia sclerotiorum	34.94	4.00e-68	252.00
IUUC-Smo-109648	Selaginella moellendorffii	45.37	5.00e-123	434.00
IUUC-Sit-109873	Setaria italica	44.79	2.00e-121	430.00
IUUC-Sly-111673	Solanum lycopersicum	45.19	2.00e-113	402.00
IUUC-Stu-112125	Solanum tuberosum	44.77	5.00e-112	398.00
IUUC-Sbi-114696	Sorghum bicolor	41.68	4.00e-109	388.00
IUUC-Sre-115134	Sporisorium reilianum	32.50	4.00e-72	265.00
IUUC-Ssc-116260	Sus scrofa	84.75	0.00e+00	903.00
IUUC-Tgu-116533	Taeniopygia guttata	84.95	0.00e+00	900.00
IUUC-Tru-117800	Takifugu rubripes	96.04	0.00e+00	991.00
IUUC-Tsy-118980	Tarsius syrichta	80.04	0.00e+00	815.00
IUUC-Tni-120334	Tetraodon nigroviridis	96.10	0.00e+00	669.00
IUUC-Tca-121807	Theobroma cacao	44.68	4.00e-121	428.00
IUUC-Tre-121920	Trichoderma reesei	32.86	9.00e-63	234.00
IUUC-Tvi-122294	Trichoderma virens	32.13	2.00e-55	210.00
IUUC-Tae-125713	Triticum aestivum	45.58	1.00e-124	439.00
IUUC-Tur-126664	Triticum urartu	41.02	3.00e-114	405.00
IUUC-Tme-127026	Tuber melanosporum	35.07	7.00e-72	265.00
IUUC-Tbe-127582	Tupaia belangeri	83.28	2.00e-173	602.00
IUUC-Ttr-128313	Tursiops truncatus	84.55	0.00e+00	894.00
IUUC-Uma-129626	Ustilago maydis	33.27	3.00e-74	272.00
IUUC-Vda-129699	Verticillium dahliae	34.78	1.00e-68	253.00
IUUC-Vpa-130593	Vicugna pacos	85.93	0.00e+00	814.00
IUUC-Vvi-131668	Vitis vinifera	44.59	8.00e-121	427.00
IUUC-Xtr-132186	Xenopus tropicalis	80.68	0.00e+00	727.00
IUUC-Xma-133212	Xiphophorus maculatus	96.04	0.00e+00	946.00
IUUC-Yli-134607	Yarrowia lipolytica	54.55	3.00e-39	154.00
IUUC-Zma-135662	Zea mays	44.81	1.00e-122	433.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence