iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034123

UUCD1 version

UUC-EqC-00957

Ensembl Protein ID

ENSECAP00000013123.1

UniProt Accession

F6TMW7; F6TMW7_HORSE

Protein Name

Uncharacterized protein

Gene Name

UBE2H

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000015420.1	ENSECAT00000016255.1	ENSECAP00000013123.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.20e-34	119.3	21	133

Active Site

Position(s)	Description	Evidence
77	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 27   ltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsilkeeekWspalsvesvlls.iqsllaepn 113
           l+e+ v++ Gp++tpYeggv+k+++++p++YPfk+P++ f++kifhPn++e+ G+vCl++++  ++W++ +++++++ s + +lla pn
   Q: 21   LNEFVVKFYGPQGTPYEGGVWKVRVDLPDKYPFKSPSIGFMNKIFHPNIDEAsGTVCLDVIN--QTWTALYDLTNIFESfLPQLLAYPN 107
           78999**********************************************99********9..*************66378999**** PP
   S: 114  pesplneeaaellkknreeykkkvre 139
           p +pln +aa ++ +++eeyk+k++e
   Q: 108  PIDPLNGDAAAMYLHRPEEYKQKIKE 133
           ***********************985 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MDTDVVKLIE SKHEVTILGG LNEFVVKFYG PQGTPYEGGV WKVRVDLPDK YPFKSPSIGF 60
MNKIFHPNID EASGTVCLDV INQTWTALYD LTNIFESFLP QLLAYPNPID PLNGDAAAMY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGCGACGG GGAGGCAGCG GCGACACCAT GTCATCCCCC AGTCCGGGCA AGAGGCGGAT 60
GGACACGGAC GTGGTCAAGC TGTATCCTTC GTGGAGGGGC GATTCGAGCT GTATGTGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000745	Aegilops tauschii	60.56	1.00e-50	192.00
IUUC-Aml-001260	Ailuropoda melanoleuca	100.00	3.00e-80	290.00
IUUC-Atr-002681	Amborella trichopoda	59.15	1.00e-50	192.00
IUUC-Apl-003547	Anas platyrhynchos	99.39	3.00e-73	266.00
IUUC-Aca-005224	Anolis carolinensis	100.00	3.00e-75	273.00
IUUC-Aly-005836	Arabidopsis lyrata	58.04	4.00e-50	190.00
IUUC-Ath-007534	Arabidopsis thaliana	58.04	2.00e-50	191.00
IUUC-Ago-007727	Ashbya gossypii	60.14	6.00e-50	190.00
IUUC-Acl-008119	Aspergillus clavatus	58.12	2.00e-54	204.00
IUUC-Afl-008412	Aspergillus flavus	65.25	7.00e-47	179.00
IUUC-Afu-008925	Aspergillus fumigatus	62.24	2.00e-52	197.00
IUUC-Ani-009294	Aspergillus nidulans	64.34	2.00e-50	191.00
IUUC-Ang-009805	Aspergillus niger	61.84	2.00e-54	204.00
IUUC-Aor-010201	Aspergillus oryzae	54.38	2.00e-48	184.00
IUUC-Ate-010441	Aspergillus terreus	66.39	1.00e-47	181.00
IUUC-Ame-010807	Astyanax mexicanus	73.99	3.00e-56	209.00
IUUC-Bta-012802	Bos taurus	100.00	3.00e-80	290.00
IUUC-Bdi-014415	Brachypodium distachyon	61.27	8.00e-51	192.00
IUUC-Bol-016385	Brassica oleracea	59.71	3.00e-49	187.00
IUUC-Bra-016989	Brassica rapa	59.71	8.00e-49	186.00
IUUC-Cel-018412	Caenorhabditis elegans	68.49	3.00e-63	234.00
IUUC-Cja-019571	Callithrix jacchus	80.23	4.00e-63	233.00
IUUC-Cfa-020811	Canis familiaris	100.00	3.00e-80	290.00
IUUC-Cpo-021889	Cavia porcellus	96.53	2.00e-76	277.00
IUUC-Cre-022956	Chlamydomonas reinhardtii	57.64	7.00e-50	189.00
IUUC-Csa-023289	Chlorocebus sabaeus	100.00	3.00e-80	290.00
IUUC-Cho-024517	Choloepus hoffmanni	76.88	1.00e-49	188.00
IUUC-Cin-025571	Ciona intestinalis	60.40	1.00e-47	182.00
IUUC-Cgl-026627	Colletotrichum gloeosporioides	65.12	4.00e-52	196.00
IUUC-Cne-027006	Cryptococcus neoformans	58.21	1.00e-47	182.00
IUUC-Cme-027171	Cyanidioschyzon merolae	59.44	3.00e-51	194.00
IUUC-Dre-027450	Danio rerio	98.27	9.00e-80	288.00
IUUC-Dno-029838	Dasypus novemcinctus	100.00	3.00e-80	290.00
IUUC-Dor-031119	Dipodomys ordii	100.00	3.00e-80	290.00
IUUC-Dse-031243	Dothistroma septosporum	61.22	1.00e-54	205.00
IUUC-Dme-031807	Drosophila melanogaster	78.03	2.00e-72	264.00
IUUC-Ete-032437	Echinops telfairi	74.57	2.00e-57	214.00
IUUC-Eeu-034543	Erinaceus europaeus	96.55	4.00e-29	120.00
IUUC-Fca-035502	Felis catus	100.00	3.00e-80	290.00
IUUC-Fal-037054	Ficedula albicollis	100.00	6.00e-76	276.00
IUUC-Fox-037912	Fusarium oxysporum	69.70	2.00e-41	160.00
IUUC-Fso-038148	Fusarium solani	63.64	2.00e-50	191.00
IUUC-Gmo-038858	Gadus morhua	95.38	7.00e-85	305.00
IUUC-Ggr-039749	Gaeumannomyces graminis	64.57	2.00e-48	185.00
IUUC-Gga-040942	Gallus gallus	100.00	3.00e-80	290.00
IUUC-Gac-042079	Gasterosteus aculeatus	94.80	6.00e-84	302.00
IUUC-Gma-042856	Glycine max	63.38	9.00e-53	199.00
IUUC-Hsa-046545	Homo sapiens	100.00	3.00e-80	290.00
IUUC-Hvu-047746	Hordeum vulgare	60.61	1.00e-47	182.00
IUUC-Itr-048474	Ictidomys tridecemlineatus	100.00	3.00e-80	290.00
IUUC-Kpa-049144	Komagataella pastoris	65.57	5.00e-47	180.00
IUUC-Lch-050589	Latimeria chalumnae	97.06	2.00e-75	274.00
IUUC-Lpe-051335	Leersia perrieri	60.56	3.00e-50	191.00
IUUC-Loc-052829	Lepisosteus oculatus	98.84	9.00e-75	272.00
IUUC-Lma-052971	Leptosphaeria maculans	60.31	2.00e-46	178.00
IUUC-Laf-053526	Loxodonta africana	100.00	2.00e-80	291.00
IUUC-Mcc-055611	Macaca mulatta	100.00	3.00e-80	290.00
IUUC-Meu-056722	Macropus eugenii	58.79	8.00e-36	142.00
IUUC-Mor-057278	Magnaporthe oryzae	65.62	5.00e-52	196.00
IUUC-Mpo-057484	Magnaporthe poae	65.22	2.00e-46	178.00
IUUC-Mtr-058579	Medicago truncatula	60.56	1.00e-51	195.00
IUUC-Mla-058926	Melampsora laricipopulina	64.54	5.00e-55	206.00
IUUC-Mga-059801	Meleagris gallopavo	100.00	3.00e-80	290.00
IUUC-Mvi-060244	Microbotryum violaceum	61.38	3.00e-53	200.00
IUUC-Mmr-061205	Microcebus murinus	100.00	3.00e-80	290.00
IUUC-Mdo-062038	Monodelphis domestica	100.00	3.00e-43	166.00
IUUC-Mmu-063974	Mus musculus	100.00	3.00e-80	290.00
IUUC-Mac-065158	Musa acuminata	64.58	1.00e-54	205.00
IUUC-Mpu-066759	Mustela putorius furo	100.00	3.00e-80	290.00
IUUC-Mlu-067674	Myotis lucifugus	99.40	1.00e-75	275.00
IUUC-Nfi-068618	Neosartorya fischeri	62.24	6.00e-52	196.00
IUUC-Ncr-068712	Neurospora crassa	69.17	7.00e-51	192.00
IUUC-Nle-069926	Nomascus leucogenys	100.00	3.00e-80	290.00
IUUC-Opr-070598	Ochotona princeps	100.00	3.00e-80	290.00
IUUC-Ont-071315	Oreochromis niloticus	95.93	5.00e-75	273.00
IUUC-Oan-073273	Ornithorhynchus anatinus	100.00	9.00e-76	275.00
IUUC-Ocu-074357	Oryctolagus cuniculus	100.00	1.00e-72	265.00
IUUC-Oba-075055	Oryza barthii	60.56	3.00e-50	191.00
IUUC-Obr-076538	Oryza brachyantha	59.86	4.00e-50	190.00
IUUC-Ogl-077784	Oryza glaberrima	60.56	3.00e-50	191.00
IUUC-Ogu-078045	Oryza glumaepatula	60.56	3.00e-50	191.00
IUUC-Oin-079163	Oryza indica	60.56	3.00e-50	191.00
IUUC-Olo-080847	Oryza longistaminata	54.79	6.00e-44	170.00
IUUC-Ome-081586	Oryza meridionalis	55.84	7.00e-48	182.00
IUUC-Oni-082913	Oryza nivara	60.56	3.00e-50	191.00
IUUC-Opu-083651	Oryza punctata	60.56	3.00e-50	191.00
IUUC-Oru-084980	Oryza rufipogon	60.56	3.00e-50	191.00
IUUC-Osa-085334	Oryza sativa	60.61	4.00e-47	179.00
IUUC-Ola-087423	Oryzias latipes	96.53	2.00e-86	310.00
IUUC-Oga-088412	Otolemur garnettii	100.00	3.00e-80	290.00
IUUC-Oar-090282	Ovis aries	97.66	2.00e-76	277.00
IUUC-Ptr-090470	Pan troglodytes	100.00	3.00e-80	290.00
IUUC-Pan-092552	Papio anubis	100.00	3.00e-80	290.00
IUUC-Psi-093516	Pelodiscus sinensis	96.55	5.00e-76	276.00
IUUC-Pno-094800	Phaeosphaeria nodorum	68.27	6.00e-44	169.00
IUUC-Ppa-095962	Physcomitrella patens	59.03	6.00e-52	196.00
IUUC-Pfo-097374	Poecilia formosa	99.42	8.00e-80	288.00
IUUC-Pab-098112	Pongo abelii	100.00	3.00e-80	290.00
IUUC-Pop-099923	Populus trichocarpa	61.81	3.00e-52	197.00
IUUC-Pca-100436	Procavia capensis	81.06	1.00e-57	214.00
IUUC-Ppe-101144	Prunus persica	62.50	2.00e-52	197.00
IUUC-Pva-102776	Pteropus vampyrus	99.42	2.00e-78	284.00
IUUC-Pgr-103325	Puccinia graminis	63.97	2.00e-52	197.00
IUUC-Ptt-104010	Puccinia triticina	62.41	8.00e-48	182.00
IUUC-Pte-104024	Pyrenophora teres	63.50	2.00e-52	198.00
IUUC-Pyt-104715	Pyrenophora triticirepentis	64.39	3.00e-51	193.00
IUUC-Rno-105699	Rattus norvegicus	98.84	5.00e-79	286.00
IUUC-Sce-106165	Saccharomyces cerevisiae	58.50	5.00e-41	160.00
IUUC-Sha-106524	Sarcophilus harrisii	100.00	2.00e-75	274.00
IUUC-Sja-107813	Schizosaccharomyces japonicus	62.94	6.00e-52	196.00
IUUC-Spo-108105	Schizosaccharomyces pombe	60.84	6.00e-52	196.00
IUUC-Ssl-108543	Sclerotinia sclerotiorum	55.17	7.00e-45	172.00
IUUC-Smo-109023	Selaginella moellendorffii	63.31	2.00e-53	201.00
IUUC-Sit-109856	Setaria italica	59.86	2.00e-50	191.00
IUUC-Sly-111324	Solanum lycopersicum	61.81	9.00e-53	199.00
IUUC-Stu-112525	Solanum tuberosum	60.56	2.00e-51	194.00
IUUC-Sar-113572	Sorex araneus	80.61	1.00e-50	192.00
IUUC-Sbi-113911	Sorghum bicolor	60.56	1.00e-50	192.00
IUUC-Sre-115027	Sporisorium reilianum	62.50	5.00e-56	209.00
IUUC-Ssc-116221	Sus scrofa	99.42	5.00e-78	282.00
IUUC-Tgu-116965	Taeniopygia guttata	100.00	2.00e-75	274.00
IUUC-Tru-117574	Takifugu rubripes	96.53	7.00e-74	269.00
IUUC-Tni-120422	Tetraodon nigroviridis	96.53	4.00e-74	270.00
IUUC-Tca-121140	Theobroma cacao	63.89	7.00e-54	202.00
IUUC-Tre-122110	Trichoderma reesei	64.89	1.00e-50	192.00
IUUC-Tvi-122592	Trichoderma virens	67.23	6.00e-49	186.00
IUUC-Tae-123045	Triticum aestivum	60.56	1.00e-50	192.00
IUUC-Tur-126414	Triticum urartu	59.86	3.00e-50	191.00
IUUC-Tme-127020	Tuber melanosporum	54.89	3.00e-40	157.00
IUUC-Tbe-128053	Tupaia belangeri	84.24	2.00e-55	207.00
IUUC-Ttr-128734	Tursiops truncatus	100.00	3.00e-80	290.00
IUUC-Uma-129334	Ustilago maydis	62.50	5.00e-56	209.00
IUUC-Vda-129953	Verticillium dahliae	57.59	7.00e-51	192.00
IUUC-Vpa-130729	Vicugna pacos	100.00	2.00e-75	274.00
IUUC-Vvi-131055	Vitis vinifera	60.14	7.00e-53	199.00
IUUC-Xtr-132368	Xenopus tropicalis	98.84	2.00e-79	287.00
IUUC-Xma-133864	Xiphophorus maculatus	99.42	8.00e-80	288.00
IUUC-Yli-134339	Yarrowia lipolytica	57.05	1.00e-53	202.00
IUUC-Zma-135728	Zea mays	59.56	1.00e-47	182.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence