iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pma-094581

UUCD1 version

UUC-PeM-00001

Ensembl Protein ID

ENSPMAP00000001163.1

UniProt Accession

S4R7I3; S4R7I3_PETMA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000001019.1	ENSPMAT00000001168.1	ENSPMAP00000001163.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-27	94.1	320	352
E3 adaptor/Cullin RING/APC_C/CDC20	3.70e-141	469.0	180	488

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gH  +v++l++ +d  +l+sG++D+++ vW+ +
   Q: 320  GHRQEVCGLKWsPDhQHLASGGNDNKLFVWNGS 352
           8***********999***************955 PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLg.ssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekk 87
           p+kvldapel+ddfylnL+dWss nvl+v+L  ++vyl+    ++v++l+dl  ++d+vtsvsw+e+g+++avGt+kg v+i+D+++ k
   Q: 180  PFKVLDAPELQDDFYLNLVDWSSLNVLSVGLYvCRVYLFLCVCAQVTRLCDLsVDGDSVTSVSWSERGNHVAVGTHKGLVQIWDAAAGK 268
           689****************************7366*****************999********************************** PP
   S: 88   kvrtltghsarv...gaLsWnaevlssGsrdgeilhrdvrvkelkl.stlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePl 172
           k+ tl+gh+arv   gaL+Wna++lssGsrd++i++rdvr++  ++ ++lq+h+qevCGlkw+ d+++LasGGnDn++ vw+ ss +P+
   Q: 269  KINTLEGHTARVagaGALAWNADQLSSGSRDRMIVQRDVRAPPVTTeRRLQGHRQEVCGLKWSPDHQHLASGGNDNKLFVWNGSSLSPV 357
           ***********955569***************************9999***************************************** PP
   S: 173  kkfkehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskva 261
           ++++eh aavkaiawsP+q++lLasGGGtaDrci+fwntltg+ l+ +dtgsqvc+l+wsk+++elvsthG+++n+i +wkypsl++va
   Q: 358  QQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQYVDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVA 446
           ***************************************************************************************** PP
   S: 262  elkgheaRvlslalspdgeaivtaagDetlrfwklfdkkkak 303
           +l+gh++Rvl+la+spdgeaivt+agDetlrfw++f+k++++
   Q: 447  KLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRST 488
           *************************************99875 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

MDPDYEHQHR LLRQINLQNT GVASPCMTPT SHRALTPSGS PFASPSKSGD RFIPTRAGAN 60
WGIGFHSTSE ENNKSPGQNR KAKDASADNG KDSLAYLALL KNELLGAGIE KVQDPQSEDR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGGCGGGC GGTCCAAACC GGCCGTGCTG AGAGGCAGCG GGTGGGAGTT TGGTAGCGCG 60
GTCGAGCAAC TCTCTGTGAC GTCATGGACC CAGACTACGA GCACCAACAC CGGCTGCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000670	Aegilops tauschii	60.98	3.00e-110	390.00
IUUC-Aml-002003	Ailuropoda melanoleuca	80.40	0.00e+00	793.00
IUUC-Atr-002753	Amborella trichopoda	53.45	2.00e-123	434.00
IUUC-Apl-003212	Anas platyrhynchos	84.46	0.00e+00	852.00
IUUC-Aly-005442	Arabidopsis lyrata	53.61	7.00e-132	462.00
IUUC-Ath-006938	Arabidopsis thaliana	53.78	8.00e-130	455.00
IUUC-Ago-007784	Ashbya gossypii	47.88	1.00e-97	348.00
IUUC-Acl-008269	Aspergillus clavatus	48.59	2.00e-126	444.00
IUUC-Afl-008432	Aspergillus flavus	49.49	1.00e-125	442.00
IUUC-Afu-008829	Aspergillus fumigatus	48.61	8.00e-127	446.00
IUUC-Ani-009471	Aspergillus nidulans	48.89	8.00e-125	439.00
IUUC-Ang-009711	Aspergillus niger	50.31	1.00e-125	441.00
IUUC-Aor-010118	Aspergillus oryzae	49.49	1.00e-125	442.00
IUUC-Ate-010534	Aspergillus terreus	49.50	2.00e-125	441.00
IUUC-Ame-011011	Astyanax mexicanus	82.18	0.00e+00	772.00
IUUC-Bgr-012013	Blumeria graminis	50.10	1.00e-126	445.00
IUUC-Bta-012586	Bos taurus	83.86	0.00e+00	847.00
IUUC-Bci-013807	Botrytis cinerea	50.70	3.00e-124	437.00
IUUC-Bdi-015033	Brachypodium distachyon	65.16	4.00e-116	410.00
IUUC-Bol-016301	Brassica oleracea	52.89	5.00e-132	462.00
IUUC-Bra-017453	Brassica rapa	52.89	4.00e-132	462.00
IUUC-Cel-018472	Caenorhabditis elegans	61.66	4.00e-135	473.00
IUUC-Cja-019929	Callithrix jacchus	83.56	0.00e+00	839.00
IUUC-Cfa-020977	Canis familiaris	83.47	0.00e+00	841.00
IUUC-Cpo-021537	Cavia porcellus	83.86	0.00e+00	846.00
IUUC-Csa-023389	Chlorocebus sabaeus	83.86	0.00e+00	843.00
IUUC-Cin-025327	Ciona intestinalis	66.24	8.00e-172	595.00
IUUC-Csv-025921	Ciona savignyi	63.65	0.00e+00	632.00
IUUC-Cgl-026631	Colletotrichum gloeosporioides	48.04	9.00e-128	449.00
IUUC-Cne-026933	Cryptococcus neoformans	58.12	4.00e-124	437.00
IUUC-Cme-027143	Cyanidioschyzon merolae	62.46	6.00e-111	394.00
IUUC-Dre-027470	Danio rerio	80.52	0.00e+00	759.00
IUUC-Dno-029629	Dasypus novemcinctus	75.11	0.00e+00	677.00
IUUC-Dor-030187	Dipodomys ordii	76.04	0.00e+00	747.00
IUUC-Dse-031502	Dothistroma septosporum	49.60	4.00e-123	433.00
IUUC-Dme-031858	Drosophila melanogaster	72.37	0.00e+00	655.00
IUUC-Ete-032562	Echinops telfairi	94.04	5.00e-123	432.00
IUUC-Eca-034210	Equus caballus	84.06	0.00e+00	848.00
IUUC-Fca-035839	Felis catus	81.08	0.00e+00	800.00
IUUC-Fal-036895	Ficedula albicollis	84.26	0.00e+00	851.00
IUUC-Fox-037814	Fusarium oxysporum	63.19	8.00e-120	421.00
IUUC-Fso-038420	Fusarium solani	48.43	1.00e-126	445.00
IUUC-Gmo-039544	Gadus morhua	79.21	0.00e+00	768.00
IUUC-Ggr-039774	Gaeumannomyces graminis	48.94	2.00e-129	454.00
IUUC-Gga-041025	Gallus gallus	84.26	0.00e+00	851.00
IUUC-Gac-041279	Gasterosteus aculeatus	81.75	0.00e+00	813.00
IUUC-Gma-042657	Glycine max	55.36	4.00e-129	452.00
IUUC-Ggo-045599	Gorilla gorilla	83.17	0.00e+00	802.00
IUUC-Hsa-046695	Homo sapiens	83.37	0.00e+00	838.00
IUUC-Hvu-047486	Hordeum vulgare	62.19	8.00e-100	354.00
IUUC-Itr-048192	Ictidomys tridecemlineatus	83.67	0.00e+00	845.00
IUUC-Kpa-049239	Komagataella pastoris	55.91	2.00e-120	424.00
IUUC-Lch-049827	Latimeria chalumnae	85.06	0.00e+00	825.00
IUUC-Lpe-051568	Leersia perrieri	61.56	2.00e-104	370.00
IUUC-Loc-052856	Lepisosteus oculatus	83.10	0.00e+00	807.00
IUUC-Mcc-055601	Macaca mulatta	83.86	0.00e+00	843.00
IUUC-Meu-056276	Macropus eugenii	61.37	2.00e-155	540.00
IUUC-Mor-057113	Magnaporthe oryzae	49.11	6.00e-129	452.00
IUUC-Mpo-057599	Magnaporthe poae	49.90	8.00e-130	456.00
IUUC-Mtr-057689	Medicago truncatula	54.51	1.00e-129	454.00
IUUC-Mla-059048	Melampsora laricipopulina	49.70	1.00e-113	401.00
IUUC-Mga-060097	Meleagris gallopavo	79.25	0.00e+00	785.00
IUUC-Mvi-060465	Microbotryum violaceum	49.80	8.00e-123	432.00
IUUC-Mmr-061151	Microcebus murinus	75.44	0.00e+00	721.00
IUUC-Mdo-063062	Monodelphis domestica	84.86	0.00e+00	855.00
IUUC-Mmu-063731	Mus musculus	83.67	0.00e+00	844.00
IUUC-Mac-065208	Musa acuminata	54.79	2.00e-122	431.00
IUUC-Mpu-066173	Mustela putorius furo	83.40	0.00e+00	842.00
IUUC-Mlu-068030	Myotis lucifugus	83.56	0.00e+00	843.00
IUUC-Nfi-068536	Neosartorya fischeri	48.61	3.00e-126	443.00
IUUC-Ncr-068734	Neurospora crassa	52.57	1.00e-130	458.00
IUUC-Nle-070163	Nomascus leucogenys	83.86	0.00e+00	844.00
IUUC-Opr-070974	Ochotona princeps	84.12	1.00e-139	487.00
IUUC-Ont-072507	Oreochromis niloticus	80.32	0.00e+00	806.00
IUUC-Oan-073634	Ornithorhynchus anatinus	89.90	1.00e-156	543.00
IUUC-Oba-075417	Oryza barthii	60.45	2.00e-104	371.00
IUUC-Obr-076123	Oryza brachyantha	67.96	1.00e-119	421.00
IUUC-Ogl-077294	Oryza glaberrima	68.28	3.00e-119	420.00
IUUC-Ogu-077996	Oryza glumaepatula	68.61	2.00e-120	424.00
IUUC-Oin-080172	Oryza indica	68.28	3.00e-119	420.00
IUUC-Olo-081068	Oryza longistaminata	68.28	3.00e-119	419.00
IUUC-Ome-081250	Oryza meridionalis	52.53	6.00e-120	422.00
IUUC-Oni-083048	Oryza nivara	68.28	3.00e-119	420.00
IUUC-Opu-083333	Oryza punctata	52.75	2.00e-120	424.00
IUUC-Oru-085001	Oryza rufipogon	68.28	3.00e-119	420.00
IUUC-Osa-086243	Oryza sativa	68.28	3.00e-119	420.00
IUUC-Ola-087094	Oryzias latipes	78.94	0.00e+00	731.00
IUUC-Oga-088911	Otolemur garnettii	84.26	0.00e+00	850.00
IUUC-Oar-089508	Ovis aries	83.86	0.00e+00	847.00
IUUC-Ptr-090967	Pan troglodytes	68.73	5.00e-151	525.00
IUUC-Pan-092147	Papio anubis	83.37	0.00e+00	838.00
IUUC-Psi-093702	Pelodiscus sinensis	83.73	0.00e+00	845.00
IUUC-Pno-095139	Phaeosphaeria nodorum	58.73	4.00e-108	383.00
IUUC-Ppa-095192	Physcomitrella patens	56.17	2.00e-129	454.00
IUUC-Pfo-096309	Poecilia formosa	79.76	0.00e+00	769.00
IUUC-Pab-098762	Pongo abelii	67.72	0.00e+00	630.00
IUUC-Pop-098924	Populus trichocarpa	54.05	1.00e-126	445.00
IUUC-Pca-100565	Procavia capensis	80.97	0.00e+00	764.00
IUUC-Ppe-101924	Prunus persica	53.50	3.00e-130	456.00
IUUC-Pva-102602	Pteropus vampyrus	81.55	0.00e+00	805.00
IUUC-Pgr-103466	Puccinia graminis	50.32	7.00e-111	393.00
IUUC-Ptt-103888	Puccinia triticina	52.45	2.00e-102	365.00
IUUC-Pte-104097	Pyrenophora teres	48.12	7.00e-124	436.00
IUUC-Pyt-104445	Pyrenophora triticirepentis	44.91	8.00e-111	392.00
IUUC-Rno-105028	Rattus norvegicus	83.47	0.00e+00	842.00
IUUC-Sce-106240	Saccharomyces cerevisiae	44.78	5.00e-94	337.00
IUUC-Sha-107107	Sarcophilus harrisii	72.78	0.00e+00	718.00
IUUC-Sja-107900	Schizosaccharomyces japonicus	48.21	1.00e-111	394.00
IUUC-Spo-108056	Schizosaccharomyces pombe	48.05	1.00e-110	391.00
IUUC-Ssl-108391	Sclerotinia sclerotiorum	51.20	1.00e-125	442.00
IUUC-Smo-108878	Selaginella moellendorffii	57.88	6.00e-136	476.00
IUUC-Sit-110563	Setaria italica	52.09	2.00e-115	408.00
IUUC-Sly-111446	Solanum lycopersicum	54.24	1.00e-128	451.00
IUUC-Stu-112491	Solanum tuberosum	53.62	7.00e-128	449.00
IUUC-Sar-112962	Sorex araneus	74.34	1.00e-109	387.00
IUUC-Sbi-114489	Sorghum bicolor	51.98	5.00e-118	416.00
IUUC-Sre-115222	Sporisorium reilianum	47.91	9.00e-125	439.00
IUUC-Ssc-116171	Sus scrofa	83.86	0.00e+00	847.00
IUUC-Tgu-116878	Taeniopygia guttata	74.31	0.00e+00	725.00
IUUC-Tru-118222	Takifugu rubripes	78.70	0.00e+00	759.00
IUUC-Tni-119863	Tetraodon nigroviridis	79.76	0.00e+00	763.00
IUUC-Tca-121599	Theobroma cacao	55.16	1.00e-128	451.00
IUUC-Tre-122249	Trichoderma reesei	49.71	2.00e-128	451.00
IUUC-Tvi-122675	Trichoderma virens	49.41	3.00e-128	450.00
IUUC-Tae-123489	Triticum aestivum	68.93	1.00e-123	434.00
IUUC-Tur-126545	Triticum urartu	57.36	5.00e-98	349.00
IUUC-Tme-127151	Tuber melanosporum	53.12	6.00e-140	489.00
IUUC-Tbe-128056	Tupaia belangeri	79.63	3.00e-148	515.00
IUUC-Ttr-129055	Tursiops truncatus	82.97	0.00e+00	835.00
IUUC-Uma-129555	Ustilago maydis	47.91	1.00e-124	439.00
IUUC-Vda-130027	Verticillium dahliae	47.60	2.00e-129	454.00
IUUC-Vvi-131749	Vitis vinifera	55.21	1.00e-128	451.00
IUUC-Xtr-132808	Xenopus tropicalis	84.68	0.00e+00	813.00
IUUC-Xma-133183	Xiphophorus maculatus	79.76	0.00e+00	769.00
IUUC-Yli-134584	Yarrowia lipolytica	63.74	8.00e-129	452.00
IUUC-Zma-135717	Zea mays	51.63	7.00e-116	409.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence