iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073147

UUCD1 version

UUC-OrA-00857

Ensembl Protein ID

ENSOANP00000019647.3

UniProt Accession

F7DTP7; F7DTP7_ORNAN

Protein Name

Uncharacterized protein

Gene Name

USP34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000012415.3	ENSOANT00000019650.3	ENSOANP00000019647.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-69	235.5	1891	2236

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           +Gl+Nlg+tCY+ S++Q+L++ipe r+++++ k++e++       ++++ l +lqk+f+ l++s+ ka++pr + k+  + ++ +++
   Q: 1891 VGLTNLGATCYLASTIQQLYMIPEARQAIFTaKYSEDM-------KHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNT 1970
           6******************************3444444.......4568899*********************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
            eq+D  Ef++ l+ ++ee                               + k++++ lF+g ++++++ l+c++vs++ e+f+++ 
   Q: 1971 GEQKDMTEFFTDLITKIEEMS----------------------------PELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVR 2029
           *****************9977............................567899******************************** PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLd 260
           ++v + +     ++ ++L++ t +++leg+n+y c++c kk++aek+  +kklP++L+++ +R++f+  ++++ek+n++++fpl+Ld
   Q: 2030 CQVADMK-----NIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLD 2111
           *******.....9************************************************************************** PP
   S: 261  lspfcts................peekqke.....kkkYeLiavvvHsGslssGHYvayvkn.......ekgkWllfdDskVtevke 319
           ++p++++                +     +     +++Y+Li+v vH+G++++GHY++++++       +++kW+lf+D +V++ + 
   Q: 2112 MTPYTEDflmgkndrkegfkeesD-----HfketeSYEYDLIGVTVHTGTADGGHYYSFIRDivnphayKNNKWYLFNDAEVKPFDS 2193
           *******99988888777776652.....0333449**************************99999988999************** PP
   S: 320  eevleetg........................staYvlfYkrr 338
           ++  +e+                         ++aY+lfYkr+
   Q: 2194 AQLASECFggemttktydsvtdkfmdfsfektHSAYMLFYKRM 2236
           ****97779********************************96 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MFVFFFLLSF SVSDIESGDG LQLRKEHTLK IFAYINSWTQ RQCLCCFKEY KHLEIFNQVV 60
CALINLVIAQ VQALRDQLCK HCTISIDSTW QDQSNQADEP LNVERESHEE ENTERQKSIE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATGTCCTTC AAATGTTTGT TTTTTTCTTT CTCCTTTCAT TTTCAGTATC AGACATTGAA 60
AGTGGTGATG GACTGCAGCT CAGAAAGGAA CATACTCTCA AGATATTTGC TTATATCAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0732--Signal

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR011030--Vitellinogen_superhlx

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0071108--P:protein K48-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002257	Ailuropoda melanoleuca	94.73	0.00e+00	6589.00
IUUC-Apl-003284	Anas platyrhynchos	95.86	0.00e+00	6355.00
IUUC-Aca-004415	Anolis carolinensis	93.85	0.00e+00	6482.00
IUUC-Acl-008140	Aspergillus clavatus	28.79	3.00e-64	241.00
IUUC-Afl-008381	Aspergillus flavus	29.20	1.00e-64	242.00
IUUC-Afu-008857	Aspergillus fumigatus	28.32	1.00e-64	242.00
IUUC-Ani-009257	Aspergillus nidulans	27.85	3.00e-56	214.00
IUUC-Ang-009759	Aspergillus niger	27.72	3.00e-64	241.00
IUUC-Aor-009931	Aspergillus oryzae	29.20	1.00e-64	242.00
IUUC-Ate-010246	Aspergillus terreus	26.25	1.00e-53	205.00
IUUC-Ame-011219	Astyanax mexicanus	65.33	0.00e+00	2491.00
IUUC-Bgr-012195	Blumeria graminis	27.04	1.00e-65	246.00
IUUC-Bta-012989	Bos taurus	94.55	0.00e+00	6546.00
IUUC-Bci-013798	Botrytis cinerea	32.68	2.00e-58	221.00
IUUC-Cja-018974	Callithrix jacchus	88.47	0.00e+00	751.00
IUUC-Cfa-021214	Canis familiaris	95.05	0.00e+00	6612.00
IUUC-Cpo-021912	Cavia porcellus	94.41	0.00e+00	4583.00
IUUC-Csa-023658	Chlorocebus sabaeus	94.59	0.00e+00	6558.00
IUUC-Cho-024971	Choloepus hoffmanni	80.80	0.00e+00	3096.00
IUUC-Cgl-026466	Colletotrichum gloeosporioides	28.84	1.00e-63	239.00
IUUC-Dre-027428	Danio rerio	86.25	0.00e+00	4685.00
IUUC-Dno-029690	Dasypus novemcinctus	94.00	0.00e+00	6413.00
IUUC-Dor-030817	Dipodomys ordii	85.04	0.00e+00	2064.00
IUUC-Dse-031423	Dothistroma septosporum	27.81	1.00e-35	145.00
IUUC-Dme-032102	Drosophila melanogaster	54.27	0.00e+00	854.00
IUUC-Ete-032552	Echinops telfairi	91.31	0.00e+00	2914.00
IUUC-Eca-033457	Equus caballus	95.23	0.00e+00	6352.00
IUUC-Eeu-035118	Erinaceus europaeus	91.24	0.00e+00	2978.00
IUUC-Fca-036213	Felis catus	93.32	0.00e+00	4932.00
IUUC-Fal-037643	Ficedula albicollis	93.75	0.00e+00	6467.00
IUUC-Fox-037971	Fusarium oxysporum	27.71	1.00e-62	235.00
IUUC-Fso-038108	Fusarium solani	27.54	2.00e-59	225.00
IUUC-Ggr-040075	Gaeumannomyces graminis	32.86	2.00e-62	234.00
IUUC-Gga-040511	Gallus gallus	93.34	0.00e+00	6499.00
IUUC-Gac-042024	Gasterosteus aculeatus	90.85	0.00e+00	4318.00
IUUC-Ggo-044924	Gorilla gorilla	91.22	0.00e+00	6073.00
IUUC-Hsa-046913	Homo sapiens	94.68	0.00e+00	6596.00
IUUC-Itr-048626	Ictidomys tridecemlineatus	94.41	0.00e+00	6598.00
IUUC-Lch-049675	Latimeria chalumnae	87.55	0.00e+00	4941.00
IUUC-Loc-052832	Lepisosteus oculatus	88.09	0.00e+00	6027.00
IUUC-Lma-053130	Leptosphaeria maculans	27.49	4.00e-60	227.00
IUUC-Laf-054169	Loxodonta africana	94.14	0.00e+00	6596.00
IUUC-Mcc-055847	Macaca mulatta	93.74	0.00e+00	6470.00
IUUC-Meu-056327	Macropus eugenii	86.34	0.00e+00	1582.00
IUUC-Mor-057152	Magnaporthe oryzae	28.35	3.00e-62	234.00
IUUC-Mpo-057310	Magnaporthe poae	26.62	4.00e-61	230.00
IUUC-Mmr-060780	Microcebus murinus	94.68	0.00e+00	6590.00
IUUC-Mdo-062308	Monodelphis domestica	93.45	0.00e+00	6205.00
IUUC-Mmu-063457	Mus musculus	93.00	0.00e+00	6491.00
IUUC-Mpu-066917	Mustela putorius furo	92.67	0.00e+00	6390.00
IUUC-Mlu-067696	Myotis lucifugus	94.56	0.00e+00	6564.00
IUUC-Nfi-068259	Neosartorya fischeri	27.24	3.00e-64	241.00
IUUC-Ncr-068911	Neurospora crassa	25.85	2.00e-59	224.00
IUUC-Nle-069586	Nomascus leucogenys	94.51	0.00e+00	6614.00
IUUC-Opr-070447	Ochotona princeps	91.38	0.00e+00	2814.00
IUUC-Ont-072396	Oreochromis niloticus	83.11	0.00e+00	5515.00
IUUC-Ocu-074324	Oryctolagus cuniculus	94.68	0.00e+00	6580.00
IUUC-Olo-080364	Oryza longistaminata	29.29	8.00e-33	135.00
IUUC-Ola-086312	Oryzias latipes	83.04	0.00e+00	5338.00
IUUC-Oga-088878	Otolemur garnettii	94.71	0.00e+00	6599.00
IUUC-Oar-089919	Ovis aries	94.52	0.00e+00	6549.00
IUUC-Ptr-090713	Pan troglodytes	95.37	0.00e+00	6098.00
IUUC-Pan-091957	Papio anubis	95.65	0.00e+00	4979.00
IUUC-Psi-093240	Pelodiscus sinensis	94.70	0.00e+00	6555.00
IUUC-Pma-094469	Petromyzon marinus	73.33	0.00e+00	4113.00
IUUC-Pno-095059	Phaeosphaeria nodorum	32.79	1.00e-56	215.00
IUUC-Pfo-097159	Poecilia formosa	80.99	0.00e+00	5570.00
IUUC-Pab-098003	Pongo abelii	94.42	0.00e+00	6280.00
IUUC-Pca-100799	Procavia capensis	89.90	0.00e+00	1917.00
IUUC-Pva-103226	Pteropus vampyrus	89.84	0.00e+00	6160.00
IUUC-Pte-104235	Pyrenophora teres	26.97	8.00e-60	226.00
IUUC-Pyt-104803	Pyrenophora triticirepentis	27.39	7.00e-61	229.00
IUUC-Rno-105389	Rattus norvegicus	93.37	0.00e+00	5388.00
IUUC-Sha-106979	Sarcophilus harrisii	95.80	0.00e+00	6613.00
IUUC-Sar-113444	Sorex araneus	87.87	0.00e+00	5761.00
IUUC-Ssc-115815	Sus scrofa	94.49	0.00e+00	5485.00
IUUC-Tgu-117470	Taeniopygia guttata	95.35	0.00e+00	6291.00
IUUC-Tru-118543	Takifugu rubripes	82.94	0.00e+00	5419.00
IUUC-Tsy-119081	Tarsius syrichta	85.90	0.00e+00	4744.00
IUUC-Tni-120294	Tetraodon nigroviridis	84.18	6.00e-167	579.00
IUUC-Tre-122057	Trichoderma reesei	29.38	1.00e-61	232.00
IUUC-Tvi-122570	Trichoderma virens	36.16	4.00e-59	224.00
IUUC-Tme-127154	Tuber melanosporum	28.15	4.00e-61	229.00
IUUC-Tbe-127801	Tupaia belangeri	83.86	0.00e+00	3208.00
IUUC-Ttr-129262	Tursiops truncatus	90.43	0.00e+00	6219.00
IUUC-Vda-129686	Verticillium dahliae	28.53	6.00e-62	233.00
IUUC-Vpa-130484	Vicugna pacos	93.00	0.00e+00	5133.00
IUUC-Xtr-131769	Xenopus tropicalis	87.25	0.00e+00	6111.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence