iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059260

UUCD1 version

UUC-MeG-00315

Ensembl Protein ID

ENSMGAP00000006282.1

UniProt Accession

G1N3I5; G1N3I5_MELGA

Protein Name

Uncharacterized protein

Gene Name

UBE3B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000006245.1	ENSMGAT00000007029.1	ENSMGAP00000006282.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	4.70e-114	381.0	707	1072

Active Site

Position(s)	Description	Evidence
1040	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           ++++k +++v+fv+     E+g+d++Gv++efl++++k++++p l+lf+++++d++ l+p+p+s++++ ++l+lFef+G++lgka++
   Q: 707  QNAMKGVIRVKFVNdlgvdEAGIDQDGVFKEFLEEIIKKVFDPALNLFKTTSGDER-LYPSPTSYIHE-NYLQLFEFVGKMLGKAVY 791
           67899*******************************************99987665.59*******76.****************** PP
   S: 84   dgrlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           +g ++d+p++++f+++llg+       s+++l+++d+e+yk+l++ik++ + di++lgl+l++  +e+++g+  ++eL+pgG++ipV
   Q: 792  EGIVVDVPFASFFLSQLLGHhhsvfYSSVDELPSLDSEFYKNLTSIKRY-DGDISDLGLTLSY--DEDVMGQLVCHELVPGGKTIPV 875
           ********************777777999********************.7799998777776..5999****************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwe 251
           tneNk +Y++l++++r++++ik+q++a+ +Gf+++i++e++++F++ el+ li+G+ +eid+edlkk+t y gg++ ++++i+w+w+
   Q: 876  TNENKISYIHLMAHFRMHTQIKSQTAALISGFRSIIKPEWIRMFSAPELQRLISGDnAEIDLEDLKKHTVYYGGFHGSHRVIIWLWD 962
           ********************************************************9****************************** PP
   S: 252  vl.eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirkdasddrlPssnTCfnyLkLPeY 313
           +l ++fs eer++fL+FvT++sr Pl Gfa+lk                        + +f+irk++   rlP+s+TCfn+LkLP+Y
   Q: 963  ILaNDFSPEERAMFLKFVTSCSRPPLLGFAYLKppfsircvevsddqdtgdtlgsvlRGFFTIRKKEPGGRLPTSSTCFNLLKLPNY 1049
           **99*************************************************************9999****************** PP
   S: 314  sskeilkekLlyAieetkgFels 336
           s+k+il+ekL+yAi++++gFels
   Q: 1050 SKKSILREKLRYAISMNTGFELS 1072
           ********************985 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MFSASQSSKA QFLDKARQAR EERRELKERE RAAVQIQALV RRFLCRCHLQ KEIRREVEDF 60
FGTAEPGASK RSALSVFRIA RKLLFVFNHK EDKERFEKLC RCILNSMDVE NEPKVWYVSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTCAGTG CCAGCCAGTC CTCCAAAGCC CAGTTCCTGG ACAAAGCACG GCAGGCCCGT 60
GAGGAGCGAC GTGAGCTGAA GGAGAGGGAG CGTGCTGCTG TGCAGATCCA GGCACTGGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS
IPR027401--Myosin-like_IQ_dom

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	39.96	9.00e-107	381.00
IUUC-Aml-002107	Ailuropoda melanoleuca	88.25	0.00e+00	1908.00
IUUC-Atr-003017	Amborella trichopoda	38.83	5.00e-111	395.00
IUUC-Apl-003328	Anas platyrhynchos	97.56	0.00e+00	2031.00
IUUC-Aly-005794	Arabidopsis lyrata	39.29	1.00e-109	390.00
IUUC-Ath-007269	Arabidopsis thaliana	39.46	2.00e-112	400.00
IUUC-Bta-013547	Bos taurus	87.78	0.00e+00	1907.00
IUUC-Bdi-014502	Brachypodium distachyon	39.25	1.00e-110	394.00
IUUC-Bol-015093	Brassica oleracea	39.82	9.00e-113	401.00
IUUC-Bra-016722	Brassica rapa	40.18	1.00e-114	407.00
IUUC-Cel-018447	Caenorhabditis elegans	39.80	0.00e+00	678.00
IUUC-Cja-019855	Callithrix jacchus	88.25	0.00e+00	1905.00
IUUC-Cfa-020066	Canis familiaris	88.03	0.00e+00	1886.00
IUUC-Cpo-021504	Cavia porcellus	87.22	0.00e+00	1891.00
IUUC-Csa-023579	Chlorocebus sabaeus	88.15	0.00e+00	1904.00
IUUC-Cho-024430	Choloepus hoffmanni	77.77	0.00e+00	1384.00
IUUC-Cin-025750	Ciona intestinalis	46.62	0.00e+00	926.00
IUUC-Csv-026016	Ciona savignyi	48.21	0.00e+00	991.00
IUUC-Dre-028271	Danio rerio	85.07	0.00e+00	1837.00
IUUC-Dno-029054	Dasypus novemcinctus	88.53	0.00e+00	1916.00
IUUC-Dor-030938	Dipodomys ordii	90.19	0.00e+00	1151.00
IUUC-Dme-031602	Drosophila melanogaster	48.39	0.00e+00	946.00
IUUC-Ete-033041	Echinops telfairi	72.23	0.00e+00	1275.00
IUUC-Eca-034411	Equus caballus	88.43	0.00e+00	1889.00
IUUC-Eeu-035201	Erinaceus europaeus	84.27	0.00e+00	801.00
IUUC-Fca-036594	Felis catus	87.31	0.00e+00	1869.00
IUUC-Fal-037317	Ficedula albicollis	94.09	0.00e+00	2050.00
IUUC-Gmo-039412	Gadus morhua	80.99	0.00e+00	1771.00
IUUC-Gga-040149	Gallus gallus	99.16	0.00e+00	2099.00
IUUC-Gac-042088	Gasterosteus aculeatus	83.72	0.00e+00	1838.00
IUUC-Gma-043839	Glycine max	39.96	2.00e-112	400.00
IUUC-Ggo-045279	Gorilla gorilla	87.78	0.00e+00	1895.00
IUUC-Hsa-045660	Homo sapiens	87.59	0.00e+00	1892.00
IUUC-Hvu-047102	Hordeum vulgare	39.72	3.00e-106	379.00
IUUC-Itr-048021	Ictidomys tridecemlineatus	79.45	0.00e+00	888.00
IUUC-Lch-050664	Latimeria chalumnae	86.58	0.00e+00	1888.00
IUUC-Lpe-050755	Leersia perrieri	37.28	3.00e-99	356.00
IUUC-Loc-052791	Lepisosteus oculatus	86.15	0.00e+00	1852.00
IUUC-Laf-053902	Loxodonta africana	88.90	0.00e+00	1925.00
IUUC-Mcc-054730	Macaca mulatta	88.25	0.00e+00	1904.00
IUUC-Meu-056527	Macropus eugenii	80.45	0.00e+00	1710.00
IUUC-Mtr-057671	Medicago truncatula	39.96	1.00e-112	400.00
IUUC-Mmr-060804	Microcebus murinus	86.38	0.00e+00	1833.00
IUUC-Mdo-062575	Monodelphis domestica	85.09	0.00e+00	1825.00
IUUC-Mmu-063636	Mus musculus	85.82	0.00e+00	1809.00
IUUC-Mac-064989	Musa acuminata	39.36	6.00e-108	385.00
IUUC-Mpu-066677	Mustela putorius furo	87.81	0.00e+00	1778.00
IUUC-Mlu-067952	Myotis lucifugus	88.06	0.00e+00	1866.00
IUUC-Nle-069153	Nomascus leucogenys	87.59	0.00e+00	1891.00
IUUC-Opr-070554	Ochotona princeps	88.91	0.00e+00	1773.00
IUUC-Ont-071372	Oreochromis niloticus	84.70	0.00e+00	1842.00
IUUC-Oan-073327	Ornithorhynchus anatinus	77.88	0.00e+00	785.00
IUUC-Ocu-074183	Oryctolagus cuniculus	86.29	0.00e+00	1860.00
IUUC-Oba-075213	Oryza barthii	38.82	3.00e-107	383.00
IUUC-Obr-076320	Oryza brachyantha	39.09	3.00e-110	392.00
IUUC-Ogl-077093	Oryza glaberrima	38.99	6.00e-110	392.00
IUUC-Oin-080058	Oryza indica	39.09	1.00e-109	391.00
IUUC-Olo-080742	Oryza longistaminata	38.82	1.00e-108	388.00
IUUC-Ome-081741	Oryza meridionalis	38.87	2.00e-102	367.00
IUUC-Opu-083529	Oryza punctata	38.99	9.00e-110	391.00
IUUC-Oru-085128	Oryza rufipogon	36.69	2.00e-96	347.00
IUUC-Osa-085557	Oryza sativa	39.09	2.00e-109	389.00
IUUC-Ola-087337	Oryzias latipes	84.24	0.00e+00	1782.00
IUUC-Oga-088342	Otolemur garnettii	87.70	0.00e+00	1848.00
IUUC-Oar-090234	Ovis aries	87.28	0.00e+00	1878.00
IUUC-Ptr-091661	Pan troglodytes	87.78	0.00e+00	1895.00
IUUC-Pan-092728	Papio anubis	87.88	0.00e+00	1897.00
IUUC-Psi-093251	Pelodiscus sinensis	94.57	0.00e+00	1882.00
IUUC-Pma-094195	Petromyzon marinus	69.99	0.00e+00	1467.00
IUUC-Ppa-095544	Physcomitrella patens	38.06	5.00e-111	395.00
IUUC-Pfo-097472	Poecilia formosa	84.79	0.00e+00	1856.00
IUUC-Pab-098570	Pongo abelii	87.78	0.00e+00	1894.00
IUUC-Pca-100110	Procavia capensis	76.59	0.00e+00	1571.00
IUUC-Ppe-101281	Prunus persica	39.18	6.00e-108	385.00
IUUC-Pva-102887	Pteropus vampyrus	83.32	0.00e+00	1760.00
IUUC-Rno-106028	Rattus norvegicus	82.85	0.00e+00	1730.00
IUUC-Sha-107331	Sarcophilus harrisii	85.94	0.00e+00	1844.00
IUUC-Smo-109488	Selaginella moellendorffii	37.32	3.00e-107	383.00
IUUC-Sit-109811	Setaria italica	39.25	8.00e-110	391.00
IUUC-Sar-113287	Sorex araneus	73.66	7.00e-176	610.00
IUUC-Sbi-114433	Sorghum bicolor	39.75	1.00e-110	394.00
IUUC-Ssc-116103	Sus scrofa	88.06	0.00e+00	1881.00
IUUC-Tgu-117275	Taeniopygia guttata	97.76	0.00e+00	2069.00
IUUC-Tru-118681	Takifugu rubripes	83.12	0.00e+00	1839.00
IUUC-Tsy-118985	Tarsius syrichta	78.42	0.00e+00	874.00
IUUC-Tni-120850	Tetraodon nigroviridis	91.73	0.00e+00	778.00
IUUC-Tca-121770	Theobroma cacao	39.36	2.00e-112	400.00
IUUC-Tur-126086	Triticum urartu	40.14	4.00e-106	379.00
IUUC-Tbe-127461	Tupaia belangeri	83.49	0.00e+00	1726.00
IUUC-Ttr-129269	Tursiops truncatus	87.59	0.00e+00	1867.00
IUUC-Vpa-130523	Vicugna pacos	77.96	8.00e-119	421.00
IUUC-Vvi-131524	Vitis vinifera	39.04	7.00e-110	391.00
IUUC-Xtr-132146	Xenopus tropicalis	87.80	0.00e+00	1902.00
IUUC-Xma-133526	Xiphophorus maculatus	84.70	0.00e+00	1852.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence