iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049794

Ensembl Protein ID

ENSLACP00000005386.2

UniProt Accession

H3A6W5; H3A6W5_LATCH

Genbank Protein ID

ENSLACP00000005386

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01193146

Gene Name

WDR44

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000004791.2	ENSLACT00000005434.2	ENSLACP00000005386.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.40e-24	83.8	652	684
UBD/Beta-Prp	4.40e-43	147.8	502	821

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sdtllvsGsdDgtikvWDlr 31
           H d vt++af   +d++++sGs Dg++++W++ 
   Q: 652  HIDFVTAIAFhprDDRYFLSGSLDGKLRLWNIP 684
           8888********555****************75 PP

UBD/Beta-Prp

   S: 37   wdvttgkllrsl.sgheaevtavkfspdgkilvtgseDrtikvwdls.......................................... 82
           +d+++ kl++ l  +h ++v+++kfs+ g +l+t+++D+++++w l+                                          
   Q: 502  YDFDQIKLVQDLsGEHMGAVWTMKFSHCGRLLATAGQDNIVRIWVLRnafdyfnnmrikyntegrvspspsqeslnssksdtdggicsd 590
           8999********667999**************************555566677888899999*************************** PP
   S: 83   ...........tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDr 159
                         ++ ++kgh++++l+ls+s+ +++l+s s d+t+r+w+++ ++cl  +  +h ++v+ +++hp + +++ sGslD+
   Q: 591  eadpddknapfRQHPFCKYKGHTADLLDLSWSK-NYFLLSSSMDKTVRLWHISRRECL--CCFQHIDFVTAIAFHPRDdRYFLSGSLDG 676
           *********************************.9***********************..7888999********************** PP
   S: 160  tvrlWdlktgk..llrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlq.....tgecvrtlnght...dnvksvrfspnderlv 238
           ++rlW+++ +k  l  +  g +t+ ++  +f +ngk+ v g +dg+ +++d +     t+  vr+ +g +   + ++ ++ +p ++ ++
   Q: 677  KLRLWNIPDKKvaLWNEVDG-QTKLITAANFCQNGKYAVIGTYDGRCIFYDTEhlkyhTQIHVRSTRGRNrvgRKITGIEPLPGETKIL 764
           *******6666114555687.********************************66554333366666665777999999999******* PP
   S: 239  sgssDgsiriWdlrsgdllktlqlhnssvisvav.lsfgdnvlvlgsedskvniwkl 294
           ++s D  ir++dlr   l  ++++  +s++ +++ ++ ++n++v+gsed+ v iw+ 
   Q: 765  VTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKAsFGHDYNYVVSGSEDKYVYIWST 821
           ********************************9956666****************86 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MASDSDTEEF FDAAEDVNLV SSPTVSPAKI VFPAIKETPE KNVDDVGNEV LQEHNQDDSK 60
EIIDRIIEES QNKNEVEDET LLTKAKRDPF DQTIGTAVAE ADDLSKIIEI NSIETVSKEI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCTGTAACA TTCGGTGCGG GCTCAGCCCC TGCGTAGCCT CGCGAGATGC TGTTTGTTGT 60
GCTGGGAGTG GGATGTTGAA TCGTGCAGGG CTGCAGCAGT CCAGCTTCCC CTTTTGCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

KEGG

lcm:102362983

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000228	Aegilops tauschii	38.07	9.00e-59	221.00
IUUC-Aml-001198	Ailuropoda melanoleuca	74.06	0.00e+00	1170.00
IUUC-Atr-002958	Amborella trichopoda	38.65	1.00e-53	205.00
IUUC-Apl-003781	Anas platyrhynchos	79.69	0.00e+00	1142.00
IUUC-Aca-005216	Anolis carolinensis	72.84	0.00e+00	1142.00
IUUC-Aly-005544	Arabidopsis lyrata	41.16	6.00e-55	209.00
IUUC-Ath-007572	Arabidopsis thaliana	40.51	3.00e-55	209.00
IUUC-Ago-007814	Ashbya gossypii	33.24	2.00e-44	174.00
IUUC-Acl-008290	Aspergillus clavatus	35.29	2.00e-60	227.00
IUUC-Afl-008536	Aspergillus flavus	43.06	5.00e-82	299.00
IUUC-Afu-008761	Aspergillus fumigatus	43.26	3.00e-87	316.00
IUUC-Ani-009270	Aspergillus nidulans	42.65	2.00e-83	303.00
IUUC-Ang-009627	Aspergillus niger	41.47	6.00e-83	302.00
IUUC-Aor-010153	Aspergillus oryzae	43.06	5.00e-82	299.00
IUUC-Ate-010263	Aspergillus terreus	41.61	6.00e-86	312.00
IUUC-Ame-011096	Astyanax mexicanus	80.16	0.00e+00	1059.00
IUUC-Bgr-012014	Blumeria graminis	44.57	1.00e-75	277.00
IUUC-Bta-012991	Bos taurus	73.76	0.00e+00	1171.00
IUUC-Bci-013651	Botrytis cinerea	40.68	5.00e-93	335.00
IUUC-Bdi-014809	Brachypodium distachyon	35.70	9.00e-62	231.00
IUUC-Bol-016551	Brassica oleracea	39.42	1.00e-51	198.00
IUUC-Bra-017269	Brassica rapa	31.58	5.00e-52	199.00
IUUC-Cel-018681	Caenorhabditis elegans	50.22	3.00e-123	436.00
IUUC-Cja-019169	Callithrix jacchus	73.60	0.00e+00	1176.00
IUUC-Cfa-020909	Canis familiaris	74.68	0.00e+00	1184.00
IUUC-Cpo-021357	Cavia porcellus	72.84	0.00e+00	1098.00
IUUC-Cre-022638	Chlamydomonas reinhardtii	34.20	1.00e-20	93.20
IUUC-Csa-023121	Chlorocebus sabaeus	73.00	0.00e+00	1155.00
IUUC-Cin-025347	Ciona intestinalis	52.02	5.00e-172	597.00
IUUC-Csv-025844	Ciona savignyi	56.98	2.00e-164	572.00
IUUC-Cgl-026610	Colletotrichum gloeosporioides	41.81	1.00e-82	301.00
IUUC-Cme-027130	Cyanidioschyzon merolae	39.10	5.00e-50	193.00
IUUC-Dre-028529	Danio rerio	80.25	0.00e+00	1084.00
IUUC-Dno-028930	Dasypus novemcinctus	67.66	0.00e+00	682.00
IUUC-Dor-030184	Dipodomys ordii	67.50	0.00e+00	1021.00
IUUC-Dse-031178	Dothistroma septosporum	36.22	5.00e-93	335.00
IUUC-Dme-032135	Drosophila melanogaster	58.09	0.00e+00	698.00
IUUC-Ete-032457	Echinops telfairi	74.25	0.00e+00	887.00
IUUC-Eca-033319	Equus caballus	74.65	0.00e+00	1164.00
IUUC-Eeu-035325	Erinaceus europaeus	68.79	0.00e+00	808.00
IUUC-Fca-036159	Felis catus	74.28	0.00e+00	1079.00
IUUC-Fal-037153	Ficedula albicollis	74.05	0.00e+00	1124.00
IUUC-Fox-037744	Fusarium oxysporum	41.23	5.00e-57	214.00
IUUC-Fso-038143	Fusarium solani	40.33	5.00e-80	292.00
IUUC-Gmo-039226	Gadus morhua	67.79	0.00e+00	1031.00
IUUC-Ggr-039923	Gaeumannomyces graminis	41.69	1.00e-78	288.00
IUUC-Gga-040349	Gallus gallus	74.21	0.00e+00	1170.00
IUUC-Gac-041620	Gasterosteus aculeatus	79.35	0.00e+00	1048.00
IUUC-Gma-044105	Glycine max	41.23	7.00e-59	222.00
IUUC-Ggo-044646	Gorilla gorilla	73.33	0.00e+00	1166.00
IUUC-Hsa-046353	Homo sapiens	73.33	0.00e+00	1167.00
IUUC-Hvu-047791	Hordeum vulgare	40.26	1.00e-59	224.00
IUUC-Itr-048620	Ictidomys tridecemlineatus	71.78	0.00e+00	1129.00
IUUC-Kpa-049365	Komagataella pastoris	31.48	2.00e-46	181.00
IUUC-Lpe-050902	Leersia perrieri	37.89	6.00e-55	209.00
IUUC-Loc-052691	Lepisosteus oculatus	85.09	0.00e+00	1156.00
IUUC-Lma-053232	Leptosphaeria maculans	37.94	1.00e-82	301.00
IUUC-Laf-054066	Loxodonta africana	73.51	0.00e+00	1162.00
IUUC-Mcc-055055	Macaca mulatta	73.00	0.00e+00	1156.00
IUUC-Meu-056678	Macropus eugenii	64.39	0.00e+00	973.00
IUUC-Mor-057274	Magnaporthe oryzae	43.06	2.00e-81	297.00
IUUC-Mpo-057592	Magnaporthe poae	41.69	1.00e-77	285.00
IUUC-Mtr-058330	Medicago truncatula	36.48	2.00e-53	204.00
IUUC-Mla-059075	Melampsora laricipopulina	36.26	2.00e-35	143.00
IUUC-Mga-059659	Meleagris gallopavo	73.87	0.00e+00	1149.00
IUUC-Mvi-060254	Microbotryum violaceum	47.70	3.00e-80	293.00
IUUC-Mmr-060832	Microcebus murinus	73.05	0.00e+00	1169.00
IUUC-Mdo-062300	Monodelphis domestica	75.08	0.00e+00	1225.00
IUUC-Mmu-064277	Mus musculus	72.52	0.00e+00	1132.00
IUUC-Mac-064884	Musa acuminata	32.19	3.00e-57	217.00
IUUC-Mpu-065914	Mustela putorius furo	72.08	0.00e+00	1165.00
IUUC-Mlu-067853	Myotis lucifugus	73.93	0.00e+00	1142.00
IUUC-Nfi-068449	Neosartorya fischeri	36.08	2.00e-60	227.00
IUUC-Ncr-068874	Neurospora crassa	43.43	4.00e-85	310.00
IUUC-Nle-069802	Nomascus leucogenys	73.33	0.00e+00	1174.00
IUUC-Opr-071139	Ochotona princeps	88.74	3.00e-162	565.00
IUUC-Ont-072128	Oreochromis niloticus	66.03	0.00e+00	1100.00
IUUC-Oan-072824	Ornithorhynchus anatinus	70.31	0.00e+00	845.00
IUUC-Ocu-074311	Oryctolagus cuniculus	73.06	0.00e+00	1160.00
IUUC-Oba-075039	Oryza barthii	37.89	9.00e-54	205.00
IUUC-Obr-076536	Oryza brachyantha	38.42	9.00e-55	207.00
IUUC-Ogl-077572	Oryza glaberrima	37.89	1.00e-53	204.00
IUUC-Ogu-078866	Oryza glumaepatula	37.89	1.00e-53	204.00
IUUC-Oin-079225	Oryza indica	37.89	1.00e-53	204.00
IUUC-Olo-080838	Oryza longistaminata	34.75	3.00e-39	156.00
IUUC-Ome-081525	Oryza meridionalis	37.63	4.00e-53	202.00
IUUC-Oni-082452	Oryza nivara	31.12	6.00e-62	232.00
IUUC-Opu-083458	Oryza punctata	37.89	2.00e-53	203.00
IUUC-Oru-085014	Oryza rufipogon	37.89	1.00e-53	204.00
IUUC-Osa-086029	Oryza sativa	37.89	1.00e-53	204.00
IUUC-Ola-086963	Oryzias latipes	76.51	0.00e+00	1023.00
IUUC-Olu-087651	Ostreococcus lucimarinus	49.22	2.00e-50	192.00
IUUC-Oga-088623	Otolemur garnettii	74.47	0.00e+00	1146.00
IUUC-Oar-090357	Ovis aries	73.75	0.00e+00	1175.00
IUUC-Pan-092290	Papio anubis	72.61	0.00e+00	1088.00
IUUC-Psi-094089	Pelodiscus sinensis	77.52	0.00e+00	1192.00
IUUC-Pma-094528	Petromyzon marinus	72.95	0.00e+00	679.00
IUUC-Pno-094806	Phaeosphaeria nodorum	37.65	4.00e-83	301.00
IUUC-Ppa-095184	Physcomitrella patens	39.36	1.00e-61	231.00
IUUC-Pfo-097366	Poecilia formosa	79.00	0.00e+00	1114.00
IUUC-Pab-098364	Pongo abelii	73.19	0.00e+00	1165.00
IUUC-Pop-099728	Populus trichocarpa	35.73	6.00e-55	208.00
IUUC-Pca-100159	Procavia capensis	64.50	0.00e+00	998.00
IUUC-Ppe-101184	Prunus persica	30.67	5.00e-55	209.00
IUUC-Pva-102846	Pteropus vampyrus	70.01	0.00e+00	1067.00
IUUC-Pte-104369	Pyrenophora teres	38.68	2.00e-86	314.00
IUUC-Pyt-104811	Pyrenophora triticirepentis	38.40	2.00e-85	310.00
IUUC-Rno-105467	Rattus norvegicus	72.18	0.00e+00	1140.00
IUUC-Sce-106277	Saccharomyces cerevisiae	38.21	5.00e-48	186.00
IUUC-Sha-106778	Sarcophilus harrisii	73.28	0.00e+00	1171.00
IUUC-Sja-107954	Schizosaccharomyces japonicus	46.67	4.00e-86	313.00
IUUC-Spo-108181	Schizosaccharomyces pombe	50.00	6.00e-87	315.00
IUUC-Smo-108748	Selaginella moellendorffii	44.16	4.00e-59	223.00
IUUC-Sit-110492	Setaria italica	37.47	6.00e-62	232.00
IUUC-Sly-111804	Solanum lycopersicum	40.50	8.00e-52	198.00
IUUC-Stu-111949	Solanum tuberosum	39.88	3.00e-54	207.00
IUUC-Sar-112958	Sorex araneus	77.52	9.00e-97	347.00
IUUC-Sbi-114454	Sorghum bicolor	36.99	4.00e-62	233.00
IUUC-Sre-114996	Sporisorium reilianum	36.89	1.00e-51	197.00
IUUC-Tgu-116614	Taeniopygia guttata	72.99	0.00e+00	1141.00
IUUC-Tru-117808	Takifugu rubripes	68.47	0.00e+00	1049.00
IUUC-Tsy-118845	Tarsius syrichta	61.53	0.00e+00	628.00
IUUC-Tni-120013	Tetraodon nigroviridis	68.31	0.00e+00	1079.00
IUUC-Tca-121635	Theobroma cacao	32.38	5.00e-52	199.00
IUUC-Tre-122175	Trichoderma reesei	44.15	1.00e-72	267.00
IUUC-Tvi-122654	Trichoderma virens	45.32	2.00e-79	290.00
IUUC-Tae-122861	Triticum aestivum	36.75	8.00e-55	208.00
IUUC-Tur-126660	Triticum urartu	31.69	4.00e-61	229.00
IUUC-Tme-126882	Tuber melanosporum	43.48	1.00e-97	350.00
IUUC-Tbe-127531	Tupaia belangeri	89.42	2.00e-162	566.00
IUUC-Ttr-128970	Tursiops truncatus	71.06	0.00e+00	1125.00
IUUC-Uma-129369	Ustilago maydis	34.86	7.00e-44	172.00
IUUC-Vda-129935	Verticillium dahliae	40.84	2.00e-80	294.00
IUUC-Vpa-130109	Vicugna pacos	79.48	0.00e+00	1004.00
IUUC-Vvi-130908	Vitis vinifera	35.33	8.00e-53	202.00
IUUC-Xtr-132836	Xenopus tropicalis	85.08	0.00e+00	1112.00
IUUC-Xma-134131	Xiphophorus maculatus	78.73	0.00e+00	1111.00
IUUC-Yli-134376	Yarrowia lipolytica	38.05	3.00e-65	243.00
IUUC-Zma-135851	Zea mays	38.81	4.00e-57	216.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence