iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028568

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast); Ubiquitin-conjugating enzyme E2D 1b

Genbank Nucleotide ID

CU326359

Gene Name

ube2d1b; ube2d1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000038576.4	ENSDART00000035762.5	ENSDARP00000033537.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.80e-57	192.8	5	139
UBD/UBC-like/UBD_UBC	9.80e-84	279.3	5	142

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel++l++dpp+++sa+pv + dl++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+tki+hPn+++nG++Cl+il+  
   Q: 5    RIQKELQDLQRDPPAQCSAGPVGD-DLFHWQATIMGPSDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILR-- 90
           9***********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++Wspal+v++vllsi+sll++pnp++pl  ++a+++k+++e+y++ +r
   Q: 91   SQWSPALTVSKVLLSICSLLCDPNPDDPLVPDIAHIYKSDKEKYNRLAR 139
           *********************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqw 89
           ri+kel+dl+rd++aq+sa++v+ddlf+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+tkiyhpninsngsicldilrsqw
   Q: 5    RIQKELQDLQRDPPAQCSAGPVGDDLFHWQATIMGPSDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILRSQW 93
           8**************************************************************************************** PP
   S: 90   saaltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           s+alt+skvlls+csll+d++pddplv++ia+iyk+dkeky+r arewt
   Q: 94   SPALTVSKVLLSICSLLCDPNPDDPLVPDIAHIYKSDKEKYNRLAREWT 142
           ************************************************8 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MALKRIQKEL QDLQRDPPAQ CSAGPVGDDL FHWQATIMGP SDSPYQGGVF FLTIHFPTDY 60
PFKPPKVAFT TKIYHPNINS NGSICLDILR SQWSPALTVS KVLLSICSLL CDPNPDDPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCGCACCGG AAGTGTGAGC TTGCTGAGCT ACAGCTGTCT CTCTTTCTCG CCGCTCACAT 60
TCGCTTTTAA CTCAGGGAAA CACAGTATTG CTGAGCTGTT TCGTAGCAAT AATATCGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0031398--P:positive regulation of protein ubiquitination
GO:0000209--P:protein polyubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

dre:324015

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001563	Ailuropoda melanoleuca	94.56	7.00e-81	292.00
IUUC-Aca-005254	Anolis carolinensis	94.56	7.00e-81	292.00
IUUC-Aly-006221	Arabidopsis lyrata	80.95	2.00e-71	261.00
IUUC-Ath-007495	Arabidopsis thaliana	80.95	9.00e-71	259.00
IUUC-Ame-011566	Astyanax mexicanus	100.00	2.00e-85	307.00
IUUC-Bta-013467	Bos taurus	94.56	7.00e-81	292.00
IUUC-Bol-016512	Brassica oleracea	81.63	1.00e-71	261.00
IUUC-Bra-016748	Brassica rapa	80.27	1.00e-71	264.00
IUUC-Cja-019302	Callithrix jacchus	94.56	7.00e-81	292.00
IUUC-Cfa-021087	Canis familiaris	94.56	7.00e-81	292.00
IUUC-Cre-022765	Chlamydomonas reinhardtii	80.95	3.00e-71	260.00
IUUC-Csa-023668	Chlorocebus sabaeus	94.56	7.00e-81	292.00
IUUC-Cho-024987	Choloepus hoffmanni	94.56	7.00e-81	292.00
IUUC-Cin-025379	Ciona intestinalis	89.04	5.00e-77	279.00
IUUC-Cme-027220	Cyanidioschyzon merolae	83.67	3.00e-72	263.00
IUUC-Dno-030067	Dasypus novemcinctus	94.56	7.00e-81	292.00
IUUC-Ete-032540	Echinops telfairi	94.56	7.00e-81	292.00
IUUC-Eca-034167	Equus caballus	94.56	7.00e-81	292.00
IUUC-Gmo-038775	Gadus morhua	95.24	3.00e-82	296.00
IUUC-Gga-040873	Gallus gallus	94.56	7.00e-81	292.00
IUUC-Gma-043733	Glycine max	81.63	4.00e-72	263.00
IUUC-Itr-048743	Ictidomys tridecemlineatus	94.56	7.00e-81	292.00
IUUC-Lch-050109	Latimeria chalumnae	89.80	9.00e-79	285.00
IUUC-Loc-051773	Lepisosteus oculatus	99.32	8.00e-85	305.00
IUUC-Mtr-057667	Medicago truncatula	80.27	1.00e-70	258.00
IUUC-Mga-060138	Meleagris gallopavo	93.57	2.00e-76	276.00
IUUC-Mmr-061212	Microcebus murinus	94.56	7.00e-81	292.00
IUUC-Mmu-063779	Mus musculus	94.56	7.00e-81	292.00
IUUC-Mac-064875	Musa acuminata	80.95	4.00e-63	233.00
IUUC-Mpu-065724	Mustela putorius furo	94.56	7.00e-81	292.00
IUUC-Mlu-067573	Myotis lucifugus	93.57	2.00e-76	276.00
IUUC-Olu-087615	Ostreococcus lucimarinus	77.55	1.00e-66	245.00
IUUC-Oga-088915	Otolemur garnettii	94.56	7.00e-81	292.00
IUUC-Ptr-091575	Pan troglodytes	94.56	7.00e-81	292.00
IUUC-Pan-092922	Papio anubis	94.56	7.00e-81	292.00
IUUC-Pca-100678	Procavia capensis	94.56	7.00e-81	292.00
IUUC-Ppe-101688	Prunus persica	80.27	6.00e-71	259.00
IUUC-Pva-102770	Pteropus vampyrus	94.56	7.00e-81	292.00
IUUC-Rno-106124	Rattus norvegicus	94.56	7.00e-81	292.00
IUUC-Sce-106463	Saccharomyces cerevisiae	80.56	2.00e-70	257.00
IUUC-Sha-106489	Sarcophilus harrisii	90.34	5.00e-77	279.00
IUUC-Ttr-128363	Tursiops truncatus	94.56	7.00e-81	292.00
IUUC-Vvi-131016	Vitis vinifera	79.59	5.00e-71	259.00
IUUC-Xtr-132284	Xenopus tropicalis	97.96	7.00e-84	302.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence