iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106489

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01002353

Gene Name

UBE2D1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000010481.1	ENSSHAT00000012325.1	ENSSHAP00000012226.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.50e-55	186.2	6	139
UBD/UBC-like/UBD_UBC	1.80e-82	274.4	7	142

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeee 90
           l +el++l++dpp+++sa+pv + dl++w+++i+Gp+d+ Y+ggvF l+++fp+dYPfkPPk+ f+tki+hPn+++nG++Cl+il+  +
   Q: 6    LSQELSDLQRDPPAHCSAGPVGD-DLFHWQATIMGPPDSAYQGGVFFLTVHFPTDYPFKPPKIAFTTKIYHPNINSNGSICLDILR--S 91
           689********************.9************************************************************9..* PP
   S: 91   kWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           +Wspal+v++vllsi+sll++pnp++pl  ++a+++k+++e+y++++r
   Q: 92   QWSPALTVSKVLLSICSLLCDPNPDDPLVPDIAQIYKSDKEKYNRHAR 139
           ********************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 3    kkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsa 91
            +el+dl+rd++a++sa++v+ddlf+++ati+gppds+y+ggvfflt+++ptdypfkppk+af+tkiyhpninsngsicldilrsqws+
   Q: 7    SQELSDLQRDPPAHCSAGPVGDDLFHWQATIMGPPDSAYQGGVFFLTVHFPTDYPFKPPKIAFTTKIYHPNINSNGSICLDILRSQWSP 95
           68*************************************************************************************** PP
   S: 92   altlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           alt+skvlls+csll+d++pddplv++ia+iyk+dkeky+r+arewt
   Q: 96   ALTVSKVLLSICSLLCDPNPDDPLVPDIAQIYKSDKEKYNRHAREWT 142
           **********************************************8 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

SNISSLSQEL SDLQRDPPAH CSAGPVGDDL FHWQATIMGP PDSAYQGGVF FLTVHFPTDY 60
PFKPPKIAFT TKIYHPNINS NGSICLDILR SQWSPALTVS KVLLSICSLL CDPNPDDPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCAAATATTT CTTCTTTGTC ACAGGAATTA AGTGATCTGC AGCGTGACCC TCCTGCCCAC 60
TGCTCAGCAG GACCTGTGGG AGATGACTGT AAGCTTTGCT CTATTGCTCG CTTTTTGCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0043234--C:protein complex
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:1902916--P:positive regulation of protein polyubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000292	Aegilops tauschii	75.71	2.00e-65	241.00
IUUC-Aml-001563	Ailuropoda melanoleuca	95.86	7.00e-82	295.00
IUUC-Atr-002782	Amborella trichopoda	77.14	3.00e-66	243.00
IUUC-Apl-003639	Anas platyrhynchos	100.00	1.00e-81	294.00
IUUC-Aca-005254	Anolis carolinensis	95.86	7.00e-82	295.00
IUUC-Aly-006221	Arabidopsis lyrata	76.76	6.00e-66	242.00
IUUC-Ath-007224	Arabidopsis thaliana	75.71	8.00e-66	241.00
IUUC-Ago-007967	Ashbya gossypii	75.34	4.00e-67	246.00
IUUC-Acl-008266	Aspergillus clavatus	76.55	7.00e-68	248.00
IUUC-Afl-008709	Aspergillus flavus	75.35	2.00e-66	246.00
IUUC-Afu-008956	Aspergillus fumigatus	77.24	4.00e-68	249.00
IUUC-Ani-009401	Aspergillus nidulans	75.17	1.00e-66	244.00
IUUC-Ang-009725	Aspergillus niger	79.20	2.00e-59	220.00
IUUC-Aor-010157	Aspergillus oryzae	76.55	1.00e-67	247.00
IUUC-Ate-010438	Aspergillus terreus	75.86	6.00e-67	245.00
IUUC-Ame-011566	Astyanax mexicanus	90.34	4.00e-77	279.00
IUUC-Bgr-012238	Blumeria graminis	71.72	3.00e-63	233.00
IUUC-Bta-013467	Bos taurus	95.86	7.00e-82	295.00
IUUC-Bci-013661	Botrytis cinerea	75.17	1.00e-67	248.00
IUUC-Bdi-014712	Brachypodium distachyon	78.57	4.00e-66	243.00
IUUC-Bol-016512	Brassica oleracea	76.76	4.00e-66	243.00
IUUC-Bra-016748	Brassica rapa	76.43	7.00e-66	244.00
IUUC-Cel-018362	Caenorhabditis elegans	84.83	7.00e-75	271.00
IUUC-Cja-019302	Callithrix jacchus	95.86	7.00e-82	295.00
IUUC-Cfa-021087	Canis familiaris	95.86	7.00e-82	295.00
IUUC-Cpo-021897	Cavia porcellus	90.65	2.00e-74	270.00
IUUC-Cre-022765	Chlamydomonas reinhardtii	74.65	1.00e-64	238.00
IUUC-Csa-023668	Chlorocebus sabaeus	95.86	7.00e-82	295.00
IUUC-Cho-024987	Choloepus hoffmanni	95.86	7.00e-82	295.00
IUUC-Cin-025379	Ciona intestinalis	81.25	4.00e-71	259.00
IUUC-Csv-026311	Ciona savignyi	80.56	9.00e-70	254.00
IUUC-Cgl-026490	Colletotrichum gloeosporioides	75.86	2.00e-67	247.00
IUUC-Cne-026957	Cryptococcus neoformans	73.61	4.00e-64	236.00
IUUC-Cme-027220	Cyanidioschyzon merolae	78.62	8.00e-69	251.00
IUUC-Dre-028568	Danio rerio	90.34	4.00e-77	279.00
IUUC-Dno-030067	Dasypus novemcinctus	95.86	7.00e-82	295.00
IUUC-Dor-030474	Dipodomys ordii	95.86	7.00e-82	295.00
IUUC-Dse-031397	Dothistroma septosporum	75.86	1.00e-67	248.00
IUUC-Dme-031594	Drosophila melanogaster	85.52	5.00e-75	272.00
IUUC-Ete-032540	Echinops telfairi	95.86	7.00e-82	295.00
IUUC-Eca-034167	Equus caballus	95.86	7.00e-82	295.00
IUUC-Eeu-034766	Erinaceus europaeus	87.86	2.00e-72	264.00
IUUC-Fca-035917	Felis catus	84.83	1.00e-74	271.00
IUUC-Fal-036904	Ficedula albicollis	87.86	6.00e-74	268.00
IUUC-Fox-038021	Fusarium oxysporum	75.86	2.00e-67	246.00
IUUC-Fso-038297	Fusarium solani	75.17	5.00e-67	245.00
IUUC-Gmo-038775	Gadus morhua	87.59	1.00e-74	271.00
IUUC-Ggr-039912	Gaeumannomyces graminis	70.67	2.00e-62	230.00
IUUC-Gga-040873	Gallus gallus	95.86	7.00e-82	295.00
IUUC-Gac-042534	Gasterosteus aculeatus	88.73	9.00e-74	268.00
IUUC-Gma-043733	Glycine max	77.46	6.00e-67	245.00
IUUC-Ggo-045361	Gorilla gorilla	87.59	9.00e-76	275.00
IUUC-Hsa-045951	Homo sapiens	95.86	7.00e-82	295.00
IUUC-Hvu-047546	Hordeum vulgare	73.57	8.00e-64	235.00
IUUC-Itr-048743	Ictidomys tridecemlineatus	95.86	7.00e-82	295.00
IUUC-Kpa-049290	Komagataella pastoris	77.46	7.00e-66	242.00
IUUC-Lch-050109	Latimeria chalumnae	84.83	8.00e-74	268.00
IUUC-Lpe-051289	Leersia perrieri	77.14	9.00e-66	241.00
IUUC-Loc-051773	Lepisosteus oculatus	90.34	7.00e-77	278.00
IUUC-Lma-053121	Leptosphaeria maculans	75.86	7.00e-68	248.00
IUUC-Laf-053673	Loxodonta africana	97.95	4.00e-83	299.00
IUUC-Mcc-055719	Macaca mulatta	95.86	7.00e-82	295.00
IUUC-Meu-056462	Macropus eugenii	87.05	2.00e-72	264.00
IUUC-Mor-057235	Magnaporthe oryzae	75.17	1.00e-66	244.00
IUUC-Mpo-057596	Magnaporthe poae	70.67	5.00e-62	229.00
IUUC-Mtr-057667	Medicago truncatula	76.06	2.00e-65	240.00
IUUC-Mla-059189	Melampsora laricipopulina	72.41	1.00e-62	231.00
IUUC-Mga-060138	Meleagris gallopavo	100.00	1.00e-81	294.00
IUUC-Mvi-060397	Microbotryum violaceum	76.55	1.00e-66	244.00
IUUC-Mmr-061212	Microcebus murinus	95.86	7.00e-82	295.00
IUUC-Mdo-062402	Monodelphis domestica	99.29	2.00e-81	293.00
IUUC-Mmu-063779	Mus musculus	95.86	7.00e-82	295.00
IUUC-Mac-064668	Musa acuminata	77.14	1.00e-66	245.00
IUUC-Mpu-065724	Mustela putorius furo	95.86	7.00e-82	295.00
IUUC-Mlu-067573	Myotis lucifugus	100.00	1.00e-81	294.00
IUUC-Nfi-068599	Neosartorya fischeri	77.24	4.00e-68	249.00
IUUC-Ncr-068677	Neurospora crassa	74.48	2.00e-66	243.00
IUUC-Nle-069950	Nomascus leucogenys	95.86	7.00e-82	295.00
IUUC-Opr-070191	Ochotona princeps	88.49	8.00e-74	268.00
IUUC-Ont-072562	Oreochromis niloticus	86.21	1.00e-74	271.00
IUUC-Oan-073149	Ornithorhynchus anatinus	95.86	2.00e-81	293.00
IUUC-Ocu-074315	Oryctolagus cuniculus	85.52	6.00e-75	272.00
IUUC-Oba-075411	Oryza barthii	77.14	1.00e-65	241.00
IUUC-Obr-076658	Oryza brachyantha	75.71	4.00e-65	239.00
IUUC-Ogl-077772	Oryza glaberrima	77.14	1.00e-65	241.00
IUUC-Ogu-078981	Oryza glumaepatula	77.14	1.00e-65	241.00
IUUC-Oin-079652	Oryza indica	77.14	1.00e-65	241.00
IUUC-Olo-080786	Oryza longistaminata	77.14	1.00e-65	241.00
IUUC-Ome-081967	Oryza meridionalis	75.71	3.00e-65	239.00
IUUC-Oni-082391	Oryza nivara	75.35	6.00e-66	244.00
IUUC-Opu-083481	Oryza punctata	76.43	3.00e-65	240.00
IUUC-Oru-085167	Oryza rufipogon	75.35	7.00e-66	243.00
IUUC-Osa-086003	Oryza sativa	75.35	1.00e-65	241.00
IUUC-Ola-087515	Oryzias latipes	86.90	5.00e-75	272.00
IUUC-Olu-087615	Ostreococcus lucimarinus	72.86	1.00e-60	224.00
IUUC-Oga-088915	Otolemur garnettii	95.86	7.00e-82	295.00
IUUC-Oar-090418	Ovis aries	99.29	7.00e-82	295.00
IUUC-Ptr-091575	Pan troglodytes	95.86	7.00e-82	295.00
IUUC-Pan-092922	Papio anubis	95.86	7.00e-82	295.00
IUUC-Psi-094076	Pelodiscus sinensis	84.83	1.00e-74	271.00
IUUC-Pma-094405	Petromyzon marinus	87.41	2.00e-69	254.00
IUUC-Pno-094765	Phaeosphaeria nodorum	75.86	7.00e-68	248.00
IUUC-Ppa-095177	Physcomitrella patens	77.14	2.00e-66	243.00
IUUC-Pfo-096867	Poecilia formosa	86.90	5.00e-75	272.00
IUUC-Pab-098137	Pongo abelii	95.86	7.00e-82	295.00
IUUC-Pop-100017	Populus trichocarpa	77.14	3.00e-66	243.00
IUUC-Pca-100678	Procavia capensis	95.86	7.00e-82	295.00
IUUC-Ppe-101387	Prunus persica	77.14	4.00e-66	243.00
IUUC-Pva-102770	Pteropus vampyrus	95.86	7.00e-82	295.00
IUUC-Pgr-103381	Puccinia graminis	73.79	4.00e-63	234.00
IUUC-Ptt-103723	Puccinia triticina	74.29	4.00e-59	219.00
IUUC-Pte-104015	Pyrenophora teres	75.86	9.00e-68	248.00
IUUC-Pyt-104701	Pyrenophora triticirepentis	75.86	9.00e-68	248.00
IUUC-Rno-106124	Rattus norvegicus	95.86	7.00e-82	295.00
IUUC-Sce-106153	Saccharomyces cerevisiae	76.87	4.00e-67	246.00
IUUC-Sja-107729	Schizosaccharomyces japonicus	76.55	2.00e-67	247.00
IUUC-Spo-108032	Schizosaccharomyces pombe	76.55	8.00e-68	248.00
IUUC-Ssl-108443	Sclerotinia sclerotiorum	75.86	4.00e-68	249.00
IUUC-Smo-109317	Selaginella moellendorffii	77.14	4.00e-66	243.00
IUUC-Sit-109936	Setaria italica	77.14	9.00e-66	243.00
IUUC-Sly-111097	Solanum lycopersicum	77.86	2.00e-66	244.00
IUUC-Stu-112192	Solanum tuberosum	77.86	2.00e-66	244.00
IUUC-Sar-113557	Sorex araneus	100.00	4.00e-81	292.00
IUUC-Sbi-114840	Sorghum bicolor	75.35	1.00e-65	241.00
IUUC-Sre-115037	Sporisorium reilianum	73.05	9.00e-64	234.00
IUUC-Ssc-115391	Sus scrofa	87.59	9.00e-76	275.00
IUUC-Tgu-117399	Taeniopygia guttata	97.89	1.00e-81	294.00
IUUC-Tru-118272	Takifugu rubripes	84.14	2.00e-73	267.00
IUUC-Tsy-118832	Tarsius syrichta	85.52	3.00e-73	266.00
IUUC-Tni-120056	Tetraodon nigroviridis	84.14	2.00e-73	267.00
IUUC-Tca-121542	Theobroma cacao	75.35	2.00e-66	244.00
IUUC-Tre-122125	Trichoderma reesei	73.79	4.00e-65	239.00
IUUC-Tvi-122296	Trichoderma virens	73.79	4.00e-65	239.00
IUUC-Tae-123340	Triticum aestivum	76.06	1.00e-66	244.00
IUUC-Tur-126518	Triticum urartu	75.71	6.00e-66	243.00
IUUC-Tme-126912	Tuber melanosporum	73.79	5.00e-66	242.00
IUUC-Tbe-128122	Tupaia belangeri	88.71	4.00e-56	209.00
IUUC-Ttr-128363	Tursiops truncatus	95.86	7.00e-82	295.00
IUUC-Uma-129648	Ustilago maydis	75.35	8.00e-66	241.00
IUUC-Vda-129695	Verticillium dahliae	75.86	2.00e-67	247.00
IUUC-Vpa-130352	Vicugna pacos	92.81	8.00e-68	248.00
IUUC-Vvi-130986	Vitis vinifera	77.14	4.00e-66	243.00
IUUC-Xtr-132284	Xenopus tropicalis	91.03	6.00e-78	281.00
IUUC-Xma-133829	Xiphophorus maculatus	84.14	8.00e-74	268.00
IUUC-Yli-134353	Yarrowia lipolytica	73.10	6.00e-66	242.00
IUUC-Zma-135569	Zea mays	75.71	3.00e-65	240.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence