iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-091704

Ensembl Protein ID

ENSPANP00000003990.1

UniProt Accession

A0A096MVU9; A0A096MVU9_PAPAN

Genbank Protein ID

ENSPANP00000003990

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01012735

Gene Name

USP48

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000017055.1	ENSPANT00000008346.1	ENSPANP00000003990.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.00e-71	240.0	90	383
ULD/UDP/UBQ/UBQ_Other	9.80e-11	41.5	948	1010

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle........kkkeklneenp........kepkgellkslqklfeelwkskkkavsprel 73
           +Gl+Nlg+tCY+N  LQ+ +   elr++l                             + + ++++++lq lf+ l++s++++++p+ +
   Q: 90   VGLTNLGATCYVNTFLQVWFLNLELRQALYLcpstcsdyV---------LgdgiqeekDYEPQTICEHLQYLFALLQNSNRRYIDPSGF 169
           6*****************************9555555433.........23333333367888************************** PP
   S: 74   lkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnv 162
           +kal+     +++ +qqDaqEf + +++ le++l                       +++k+   ++++++ F g++   ++c++c+++
   Q: 170  VKALG-----LDTGQQQDAQEFSKLFMSLLEDTL-----------------------SKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRE 230
           ****9.....78899*******************.......................457889999*********************** PP
   S: 163  ssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekink 251
           s+  ++f++l+l+++g++     +l+dc+++f kee+leg+n+y+ce+c++kq+a++k++l +lP +L l+L+Rf f++++++++k+n+
   Q: 231  SKLLSKFYELELNIQGHK-----QLTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNT 314
           ******************.....9***************************************************************** PP
   S: 252  kvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn.ekgkWllfdDskVtevkeeev 322
           ++ f + Ld++p+++++      ++ YeL+av++H G s+ sGHY+a+vk+ ++g+W++f+D+ +++++ ++ 
   Q: 315  YIGFSEILDMEPYVEHKGG----SYVYELSAVLIHRGvSAYSGHYIAHVKDpQSGEWYKFNDEDIEKMEGKKL 383
           **************99554....79**************************44555***********987776 PP

ULD/UDP/UBQ/UBQ_Other

   S: 16   k...vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekks 74
           k   v+   t +eLK +i +++++ p +q+L ++GkiL +d+ tL+ +g+ ++s+i+l  +++
   Q: 948  KallVSANQTLKELKIQIMHAFSVAPFDQNLSIDGKILsDDCATLGTLGVIPESVILLKADEP 1010
           344489999************************************************988775 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MAPRLQLEKA AWRWAETVRP EEVSQEHIET AYRIWLEPCI RGVCSRRNCK GNPNCLVGIG 60
EHIWLGEIDE NSFHNIDDPN CERRKKNSFV GLTNLGATCY VNTFLQVWFL NLELRQALYL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCCCGC GGCTGCAACT GGAGAAGGCG GCCTGGCGCT GGGCGGAGAC GGTGCGGCCC 60
GAGGAGGTGT CGCAGGAGCA CATCGAGACC GCTTACCGCA TCTGGCTGGA GCCCTGCATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033841--USP48
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS50053--UBIQUITIN_2
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000130	Aegilops tauschii	31.13	2.00e-75	278.00
IUUC-Aml-001357	Ailuropoda melanoleuca	94.04	0.00e+00	1981.00
IUUC-Atr-002976	Amborella trichopoda	31.85	7.00e-77	282.00
IUUC-Apl-003773	Anas platyrhynchos	84.34	0.00e+00	1602.00
IUUC-Aca-004466	Anolis carolinensis	75.98	0.00e+00	803.00
IUUC-Aly-006249	Arabidopsis lyrata	28.42	2.00e-63	237.00
IUUC-Ath-006700	Arabidopsis thaliana	36.70	3.00e-59	224.00
IUUC-Ame-011554	Astyanax mexicanus	66.13	0.00e+00	1380.00
IUUC-Bta-012573	Bos taurus	93.38	0.00e+00	1966.00
IUUC-Bdi-014149	Brachypodium distachyon	30.89	5.00e-75	276.00
IUUC-Bol-016289	Brassica oleracea	25.76	9.00e-76	278.00
IUUC-Bra-017205	Brassica rapa	29.61	5.00e-69	256.00
IUUC-Cel-018662	Caenorhabditis elegans	28.02	2.00e-28	121.00
IUUC-Cja-019991	Callithrix jacchus	93.74	0.00e+00	1985.00
IUUC-Cfa-020294	Canis familiaris	94.81	0.00e+00	2003.00
IUUC-Cpo-021706	Cavia porcellus	91.56	0.00e+00	1857.00
IUUC-Cre-022636	Chlamydomonas reinhardtii	36.48	1.00e-42	169.00
IUUC-Csa-023931	Chlorocebus sabaeus	96.15	0.00e+00	2013.00
IUUC-Cho-024566	Choloepus hoffmanni	97.48	2.00e-159	556.00
IUUC-Cin-025307	Ciona intestinalis	47.00	6.00e-75	273.00
IUUC-Csv-026006	Ciona savignyi	35.82	1.00e-141	497.00
IUUC-Cne-027065	Cryptococcus neoformans	27.89	3.00e-65	244.00
IUUC-Dre-027624	Danio rerio	66.60	0.00e+00	1421.00
IUUC-Dno-029633	Dasypus novemcinctus	91.65	0.00e+00	1233.00
IUUC-Dor-030809	Dipodomys ordii	98.19	0.00e+00	685.00
IUUC-Ete-032818	Echinops telfairi	84.65	0.00e+00	872.00
IUUC-Eca-033692	Equus caballus	94.33	0.00e+00	1988.00
IUUC-Eeu-035185	Erinaceus europaeus	75.00	0.00e+00	798.00
IUUC-Fca-035676	Felis catus	94.51	0.00e+00	1997.00
IUUC-Fal-036913	Ficedula albicollis	83.48	0.00e+00	1744.00
IUUC-Gmo-038532	Gadus morhua	63.10	0.00e+00	1314.00
IUUC-Gga-041041	Gallus gallus	83.67	0.00e+00	1734.00
IUUC-Gac-042570	Gasterosteus aculeatus	64.05	0.00e+00	1352.00
IUUC-Gma-043910	Glycine max	27.02	7.00e-80	292.00
IUUC-Ggo-045367	Gorilla gorilla	93.76	0.00e+00	1936.00
IUUC-Hsa-046019	Homo sapiens	95.77	0.00e+00	2006.00
IUUC-Hvu-047303	Hordeum vulgare	31.96	8.00e-60	224.00
IUUC-Itr-048319	Ictidomys tridecemlineatus	91.60	0.00e+00	1963.00
IUUC-Lch-049989	Latimeria chalumnae	73.69	0.00e+00	1563.00
IUUC-Lpe-051612	Leersia perrieri	31.80	9.00e-76	278.00
IUUC-Loc-052756	Lepisosteus oculatus	68.46	0.00e+00	1473.00
IUUC-Laf-054043	Loxodonta africana	92.53	0.00e+00	1973.00
IUUC-Mcc-054986	Macaca mulatta	94.97	0.00e+00	2002.00
IUUC-Meu-056228	Macropus eugenii	77.47	0.00e+00	858.00
IUUC-Mtr-058610	Medicago truncatula	41.85	3.00e-61	230.00
IUUC-Mga-059896	Meleagris gallopavo	83.13	0.00e+00	1640.00
IUUC-Mvi-060269	Microbotryum violaceum	37.18	2.00e-63	238.00
IUUC-Mmr-060887	Microcebus murinus	94.13	0.00e+00	1984.00
IUUC-Mdo-062506	Monodelphis domestica	89.81	0.00e+00	1897.00
IUUC-Mmu-063642	Mus musculus	88.94	0.00e+00	1914.00
IUUC-Mac-064896	Musa acuminata	31.44	2.00e-73	271.00
IUUC-Mpu-066194	Mustela putorius furo	94.13	0.00e+00	1980.00
IUUC-Mlu-067233	Myotis lucifugus	92.85	0.00e+00	1960.00
IUUC-Nle-069052	Nomascus leucogenys	94.96	0.00e+00	1996.00
IUUC-Opr-070890	Ochotona princeps	89.73	0.00e+00	1165.00
IUUC-Ont-071450	Oreochromis niloticus	63.39	0.00e+00	1304.00
IUUC-Oan-073252	Ornithorhynchus anatinus	88.91	0.00e+00	1053.00
IUUC-Ocu-073796	Oryctolagus cuniculus	92.43	0.00e+00	1677.00
IUUC-Oba-075563	Oryza barthii	31.56	9.00e-78	285.00
IUUC-Obr-076394	Oryza brachyantha	31.80	2.00e-77	284.00
IUUC-Ogl-077339	Oryza glaberrima	38.44	6.00e-40	157.00
IUUC-Ogu-079007	Oryza glumaepatula	32.00	6.00e-70	259.00
IUUC-Oin-079997	Oryza indica	31.56	4.00e-78	286.00
IUUC-Olo-080364	Oryza longistaminata	31.56	6.00e-78	285.00
IUUC-Ome-081165	Oryza meridionalis	32.01	2.00e-70	261.00
IUUC-Oni-083026	Oryza nivara	31.56	4.00e-78	286.00
IUUC-Opu-083284	Oryza punctata	32.16	1.00e-69	258.00
IUUC-Oru-084797	Oryza rufipogon	31.56	5.00e-78	286.00
IUUC-Osa-086221	Oryza sativa	38.44	6.00e-40	157.00
IUUC-Ola-086568	Oryzias latipes	64.72	0.00e+00	1363.00
IUUC-Oga-088687	Otolemur garnettii	92.69	0.00e+00	1966.00
IUUC-Oar-090345	Ovis aries	93.28	0.00e+00	1875.00
IUUC-Ptr-090734	Pan troglodytes	95.77	0.00e+00	2006.00
IUUC-Psi-092937	Pelodiscus sinensis	83.46	0.00e+00	1525.00
IUUC-Ppa-095808	Physcomitrella patens	28.21	9.00e-67	249.00
IUUC-Pab-098129	Pongo abelii	95.86	0.00e+00	2008.00
IUUC-Pop-099494	Populus trichocarpa	27.13	9.00e-76	278.00
IUUC-Pca-100647	Procavia capensis	97.89	0.00e+00	684.00
IUUC-Ppe-102091	Prunus persica	40.86	3.00e-65	243.00
IUUC-Pva-102719	Pteropus vampyrus	93.56	0.00e+00	1965.00
IUUC-Rno-105363	Rattus norvegicus	90.96	0.00e+00	1931.00
IUUC-Sha-107620	Sarcophilus harrisii	86.43	0.00e+00	1761.00
IUUC-Smo-109487	Selaginella moellendorffii	27.49	3.00e-80	293.00
IUUC-Sit-110683	Setaria italica	32.17	1.00e-76	281.00
IUUC-Sly-111377	Solanum lycopersicum	29.15	3.00e-76	280.00
IUUC-Stu-111969	Solanum tuberosum	31.12	4.00e-65	242.00
IUUC-Sar-113099	Sorex araneus	92.01	0.00e+00	1646.00
IUUC-Sbi-113833	Sorghum bicolor	42.14	8.00e-57	213.00
IUUC-Ssc-115279	Sus scrofa	85.49	0.00e+00	1273.00
IUUC-Tgu-117519	Taeniopygia guttata	81.04	0.00e+00	1599.00
IUUC-Tru-117651	Takifugu rubripes	63.78	0.00e+00	1348.00
IUUC-Tsy-119201	Tarsius syrichta	90.44	0.00e+00	1733.00
IUUC-Tni-120840	Tetraodon nigroviridis	64.89	0.00e+00	1371.00
IUUC-Tca-121674	Theobroma cacao	39.71	1.00e-64	241.00
IUUC-Tae-125247	Triticum aestivum	25.75	2.00e-78	288.00
IUUC-Tur-126599	Triticum urartu	30.97	7.00e-75	275.00
IUUC-Tbe-127782	Tupaia belangeri	82.96	0.00e+00	1661.00
IUUC-Ttr-128312	Tursiops truncatus	93.08	0.00e+00	1951.00
IUUC-Vpa-130348	Vicugna pacos	93.66	0.00e+00	1883.00
IUUC-Vvi-131353	Vitis vinifera	38.71	1.00e-60	228.00
IUUC-Xtr-132172	Xenopus tropicalis	68.37	0.00e+00	1290.00
IUUC-Xma-133263	Xiphophorus maculatus	65.69	0.00e+00	1335.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence