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Tag Content
UUCD2 ID IUUC-Ssc-115644
UUCD1 version UUC-SuS-00074
Ensembl Protein ID ENSSSCP00000021692.1
UniProt Accession F1RHW0; F1RHW0_PIG
Genbank Protein ID ENSSSCP00000021692
Protein Name Nitric oxide synthase-interacting protein
Genbank Nucleotide ID FP102665
Gene Name NOSIP
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSSCG00000029154.1 ENSSSCT00000031851.1 ENSSSCP00000021692.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/U-box 1.90e-15 57.0 40 79
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/U-box
   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggk 41
           v ++ +C +sl++ +dPvv+p+G+ y+r++I +++ +++k
   Q: 40   VKDFDCCCLSLQPCHDPVVTPDGYLYEREAILEYILHQKK 79
           567789*****************************98887 PP
   
Organism Sus scrofa
Functional Description
(View)

Functional Description


     Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.
 Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.
Protein Sequence
(Fasta)
MTRHGKNCTA GAVYTYHEKK KDTAASGYGT QNIRLSRDAV KDFDCCCLSL QPCHDPVVTP 60
DGYLYEREAI LEYILHQKKE IARQMKAYEK QRGARREEQK ELQRAAAQDQ VRGFLEKEAA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ssc-115644|E3,U-box|Sus scrofa
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAAGAGAAGA AGGGAAGACT TACCTAGCCA GAAGAGAGAC CTCCGCAACT AGGGGCAGAT 60
CTACTTCCTG TCTCTTCCGC CGGCCGGAAG TGTGTAGAGC GGGGAGGGAA AACAGCGCTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ssc-115644|E3,U-box|Sus scrofa
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR016818--Nitric_oxide_synth-interacting
IPR031790--Znf-NOSIP
IPR013083--Znf_RING/FYVE/PHD
Pfam

PF15906--zf-NOSIP
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003723--F:RNA binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0051001--P:negative regulation of nitric-oxide synthase activity
GO:0016567--P:protein ubiquitination
KEGG ssc:100518311
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000769 Aegilops tauschii 46.51 1.00e-16 80.90
IUUC-Aml-002069 Ailuropoda melanoleuca 93.31 2.00e-167 580.00
IUUC-Atr-002661 Amborella trichopoda 31.85 5.00e-30 124.00
IUUC-Aca-004630 Anolis carolinensis 76.08 9.00e-138 482.00
IUUC-Aly-006316 Arabidopsis lyrata 30.10 1.00e-29 123.00
IUUC-Ath-007000 Arabidopsis thaliana 29.45 9.00e-29 120.00
IUUC-Acl-008175 Aspergillus clavatus 32.74 1.00e-05 43.90
IUUC-Afl-008440 Aspergillus flavus 34.78 8.00e-06 44.70
IUUC-Afu-009012 Aspergillus fumigatus 33.91 3.00e-06 45.80
IUUC-Ani-009153 Aspergillus nidulans 32.54 5.00e-03 35.00
IUUC-Ang-009556 Aspergillus niger 33.91 8.00e-06 44.70
IUUC-Aor-009892 Aspergillus oryzae 34.78 8.00e-06 44.70
IUUC-Ame-011874 Astyanax mexicanus 63.46 3.00e-110 390.00
IUUC-Bgr-012090 Blumeria graminis 25.52 2.00e-05 43.10
IUUC-Bta-012956 Bos taurus 97.68 8.00e-175 605.00
IUUC-Bci-013897 Botrytis cinerea 42.50 7.00e-10 57.80
IUUC-Bdi-014968 Brachypodium distachyon 30.64 2.00e-33 135.00
IUUC-Bol-015578 Brassica oleracea 31.92 8.00e-35 140.00
IUUC-Bra-017234 Brassica rapa 31.92 8.00e-35 140.00
IUUC-Cel-018637 Caenorhabditis elegans 41.36 3.00e-58 218.00
IUUC-Cja-019632 Callithrix jacchus 94.35 5.00e-170 589.00
IUUC-Cfa-020192 Canis familiaris 96.01 3.00e-172 597.00
IUUC-Cpo-021939 Cavia porcellus 91.69 2.00e-157 547.00
IUUC-Cre-023005 Chlamydomonas reinhardtii 34.22 2.00e-43 168.00
IUUC-Csa-023802 Chlorocebus sabaeus 94.68 5.00e-170 589.00
IUUC-Cho-024637 Choloepus hoffmanni 77.88 1.00e-83 301.00
IUUC-Cin-025180 Ciona intestinalis 51.66 4.00e-86 310.00
IUUC-Csv-026206 Ciona savignyi 54.42 2.00e-43 168.00
IUUC-Cgl-026696 Colletotrichum gloeosporioides 24.65 4.00e-13 68.60
IUUC-Cne-026827 Cryptococcus neoformans 36.36 9.00e-07 47.40
IUUC-Dre-028092 Danio rerio 64.61 2.00e-117 414.00
IUUC-Dno-029501 Dasypus novemcinctus 89.74 3.00e-145 508.00
IUUC-Dor-030542 Dipodomys ordii 91.75 4.00e-164 570.00
IUUC-Dse-031188 Dothistroma septosporum 24.58 7.00e-14 71.20
IUUC-Dme-031734 Drosophila melanogaster 48.54 7.00e-79 286.00
IUUC-Eca-033577 Equus caballus 97.67 5.00e-176 609.00
IUUC-Fca-035761 Felis catus 97.01 2.00e-173 600.00
IUUC-Fox-037703 Fusarium oxysporum 25.77 1.00e-07 50.40
IUUC-Fso-038208 Fusarium solani 27.30 5.00e-14 71.60
IUUC-Gmo-038523 Gadus morhua 61.46 3.00e-62 230.00
IUUC-Ggr-040087 Gaeumannomyces graminis 41.03 6.00e-10 58.20
IUUC-Gac-042621 Gasterosteus aculeatus 60.38 2.00e-108 385.00
IUUC-Gma-042698 Glycine max 31.74 2.00e-32 132.00
IUUC-Ggo-045357 Gorilla gorilla 94.68 2.00e-170 590.00
IUUC-Hsa-046195 Homo sapiens 94.68 2.00e-170 590.00
IUUC-Hvu-047174 Hordeum vulgare 30.77 9.00e-35 140.00
IUUC-Itr-048487 Ictidomys tridecemlineatus 94.68 5.00e-164 569.00
IUUC-Lch-050569 Latimeria chalumnae 68.27 6.00e-116 409.00
IUUC-Lpe-050992 Leersia perrieri 36.10 1.00e-22 100.00
IUUC-Loc-052522 Lepisosteus oculatus 69.10 3.00e-117 414.00
IUUC-Lma-053254 Leptosphaeria maculans 39.24 1.00e-09 57.40
IUUC-Laf-053397 Loxodonta africana 96.04 2.00e-171 594.00
IUUC-Mcc-054681 Macaca mulatta 94.68 4.00e-170 590.00
IUUC-Meu-056723 Macropus eugenii 84.16 4.00e-152 530.00
IUUC-Mor-056961 Magnaporthe oryzae 37.27 3.00e-10 59.30
IUUC-Mpo-057359 Magnaporthe poae 24.72 1.00e-06 46.60
IUUC-Mtr-058063 Medicago truncatula 31.97 2.00e-33 135.00
IUUC-Mla-059004 Melampsora laricipopulina 31.53 4.00e-25 108.00
IUUC-Mvi-060460 Microbotryum violaceum 28.87 1.00e-25 109.00
IUUC-Mmr-060847 Microcebus murinus 96.35 1.00e-172 598.00
IUUC-Mdo-062480 Monodelphis domestica 85.48 5.00e-154 536.00
IUUC-Mmu-063809 Mus musculus 93.02 3.00e-166 577.00
IUUC-Mac-064870 Musa acuminata 31.40 5.00e-33 134.00
IUUC-Mpu-066322 Mustela putorius furo 97.36 1.00e-174 605.00
IUUC-Mlu-067556 Myotis lucifugus 93.42 4.00e-160 556.00
IUUC-Nfi-068440 Neosartorya fischeri 33.91 4.00e-06 45.80
IUUC-Ncr-068898 Neurospora crassa 38.46 8.00e-08 51.20
IUUC-Nle-070049 Nomascus leucogenys 95.02 2.00e-170 591.00
IUUC-Opr-070972 Ochotona princeps 89.84 4.00e-157 546.00
IUUC-Ont-071682 Oreochromis niloticus 65.89 7.00e-117 412.00
IUUC-Oan-073296 Ornithorhynchus anatinus 98.31 1.00e-32 131.00
IUUC-Ocu-074218 Oryctolagus cuniculus 91.43 1.00e-134 471.00
IUUC-Oba-075284 Oryza barthii 32.08 5.00e-34 137.00
IUUC-Obr-076651 Oryza brachyantha 32.31 6.00e-36 144.00
IUUC-Ogl-077899 Oryza glaberrima 32.08 5.00e-34 137.00
IUUC-Ogu-078477 Oryza glumaepatula 32.42 3.00e-34 138.00
IUUC-Oin-080011 Oryza indica 32.08 5.00e-34 137.00
IUUC-Olo-080545 Oryza longistaminata 31.66 4.00e-27 115.00
IUUC-Ome-081543 Oryza meridionalis 32.08 5.00e-34 137.00
IUUC-Oni-082955 Oryza nivara 32.08 5.00e-34 137.00
IUUC-Opu-083565 Oryza punctata 31.74 6.00e-34 137.00
IUUC-Oru-084474 Oryza rufipogon 32.08 5.00e-34 137.00
IUUC-Osa-085913 Oryza sativa 32.08 5.00e-34 137.00
IUUC-Ola-086851 Oryzias latipes 67.77 2.00e-120 424.00
IUUC-Olu-087724 Ostreococcus lucimarinus 33.01 1.00e-12 66.60
IUUC-Oga-087970 Otolemur garnettii 94.70 1.00e-169 588.00
IUUC-Oar-089756 Ovis aries 94.06 5.00e-163 566.00
IUUC-Ptr-091485 Pan troglodytes 93.69 9.00e-167 578.00
IUUC-Pan-091832 Papio anubis 95.02 7.00e-171 592.00
IUUC-Pma-094551 Petromyzon marinus 62.54 3.00e-108 384.00
IUUC-Pno-094830 Phaeosphaeria nodorum 26.84 6.00e-09 54.70
IUUC-Ppa-095255 Physcomitrella patens 29.57 1.00e-30 126.00
IUUC-Pfo-096373 Poecilia formosa 65.36 4.00e-117 414.00
IUUC-Pab-098247 Pongo abelii 94.68 4.00e-170 590.00
IUUC-Pop-099186 Populus trichocarpa 31.40 8.00e-31 127.00
IUUC-Pca-100677 Procavia capensis 92.00 2.00e-140 491.00
IUUC-Ppe-101403 Prunus persica 30.61 1.00e-30 126.00
IUUC-Pva-103000 Pteropus vampyrus 96.68 1.00e-174 604.00
IUUC-Pgr-103663 Puccinia graminis 30.34 4.00e-30 125.00
IUUC-Ptt-103712 Puccinia triticina 40.00 4.00e-09 54.70
IUUC-Pte-104287 Pyrenophora teres 26.95 4.00e-17 81.60
IUUC-Pyt-104579 Pyrenophora triticirepentis 24.73 2.00e-09 56.60
IUUC-Rno-106069 Rattus norvegicus 93.36 5.00e-167 579.00
IUUC-Sha-106553 Sarcophilus harrisii 84.82 2.00e-153 534.00
IUUC-Smo-108874 Selaginella moellendorffii 32.24 3.00e-38 152.00
IUUC-Sit-110307 Setaria italica 32.08 3.00e-33 135.00
IUUC-Sly-111094 Solanum lycopersicum 31.89 5.00e-33 134.00
IUUC-Stu-112363 Solanum tuberosum 32.23 6.00e-33 134.00
IUUC-Sar-113480 Sorex araneus 95.35 2.00e-159 554.00
IUUC-Sbi-113939 Sorghum bicolor 32.08 8.00e-34 137.00
IUUC-Tru-118781 Takifugu rubripes 65.15 8.00e-120 422.00
IUUC-Tni-119672 Tetraodon nigroviridis 73.56 2.00e-34 136.00
IUUC-Tca-121795 Theobroma cacao 32.08 5.00e-35 140.00
IUUC-Tre-122037 Trichoderma reesei 36.36 2.00e-08 52.80
IUUC-Tvi-122524 Trichoderma virens 25.77 4.00e-17 81.60
IUUC-Tae-122828 Triticum aestivum 31.10 5.00e-35 140.00
IUUC-Tur-126387 Triticum urartu 31.27 3.00e-28 119.00
IUUC-Tme-127111 Tuber melanosporum 40.00 1.00e-09 57.00
IUUC-Ttr-128227 Tursiops truncatus 97.01 5.00e-174 602.00
IUUC-Vda-129924 Verticillium dahliae 26.77 4.00e-15 75.50
IUUC-Vpa-130802 Vicugna pacos 97.75 1.00e-45 176.00
IUUC-Vvi-131105 Vitis vinifera 32.76 3.00e-33 135.00
IUUC-Xtr-132830 Xenopus tropicalis 65.94 3.00e-122 431.00
IUUC-Xma-133618 Xiphophorus maculatus 66.12 9.00e-112 395.00
IUUC-Zma-135389 Zea mays 31.74 1.00e-32 133.00
Created Date 25-Jun-2017

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