iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tca-121626

Ensembl Protein ID

EOY27686

UniProt Accession

A0A061GDR2; A0A061GDR2_THECC

Genbank Protein ID

EOY27686.1

Protein Name

Cullin-4B isoform 1

Genbank Nucleotide ID

CM001884

Gene Name

TCM_029474

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TCM_029474	EOY27686	EOY27686
TCM_029474	EOY27687	EOY27687

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	2.60e-188	628.5	125	720

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 1    klreavkkilrqesvkkeyeelytavynlclskvgaklYkklkevleefi.kqvkkkveesedeq.lLktynreWekfreqlkvlrkifayldrtyvkksk 99
           kl++a+++i  ++    ++e+ly+av nlcl+k+g  lY+++++ +ee+i +++++ v +s d   +L  ++++W++ + q+ ++r i +yldrtyvk++ 
   Q: 125  KLKSAINAIFLKQPDSCDLEKLYQAVNNLCLHKMGGSLYQRIEKECEEHIsAALRSLVGQSPDLVvFLSLVEKCWQDLCDQMLMIRGIALYLDRTYVKQTP 225
           58999*********************************************8888999999999999*********************************** PP
   S: 100  kvsevrkLaldlwrkei..vedikkrllelllklieaeRkgeavdrrllsgvveslveLslnklaiykesFEakfleatqefykaesaeflqenevdeYlk 198
           +v + ++++l+l+rk++  +++++++++  ll++ie+eR geav+r ll+ + +++  L+     iy esFE++fle t+efy+ae  +++q+++v +Ylk
   Q: 226  NVRSLWDMGLQLFRKHLslASEVEHKTVTGLLRMIESERLGEAVERTLLNHLLKMFTALG-----IYSESFEKPFLECTSEFYAAEGMKYMQQSDVPDYLK 321
           ***************9633677************************************96.....************************************ PP
   S: 199  kvearlneeeeraaryleestetkLlevvekeliakhlesll.aelvallrdkktedlsrmykLlsrvlngleellkeleshikeqgkaaltaeekekdpk 298
           +ve rl+ee+er+  yl++ t ++L+++ e++l++ h+ ++l +++  l++ ++ edl+rmy+L+srv n le l++ l+s+i+  g+ ++ +eek+kd  
   Q: 322  HVEMRLHEEHERCLLYLDALTRKPLIATAERQLLERHIPAILdKGFMMLMDGHRIEDLQRMYSLFSRV-NALESLRQALSSYIRRTGQGIVLDEEKDKD-- 419
           ******************************************999**********************9.68****************************.. PP
   S: 299  kyVerllelknklqklvseaFnndakFlkaldkafetfvnknsvlkaakspEllAryiDqlLrksskglteeeleaqldkvllvfkyisekdvFekyYkkh 399
            +V++lle+k  l+++ +e+F+++++F ++++ afe+ +n +      + +El+A++ D++Lr+++kg+ eeele +ldkvl++f++i++kdvFe++Ykk+
   Q: 420  -MVPSLLEFKASLDSIWEESFSKNEAFCNTIKDAFEHLINLR----QNRPAELIAKFLDEKLRAGNKGTSEEELEGTLDKVLVLFRFIQGKDVFEAFYKKD 515
           .****************************************9....56666************************************************** PP
   S: 400  LakRLlsgksasseaEesviekLkeecgaeftskLerMfqdlkvSedlnrqFkeekentees.esvelsvlvLsagaWptasetekvsLPaelektiekfe 499
           LakRLl+gksas +aE+s+i+kLk+ecg +ft+kLe+Mf+d+++S+++n+ Fk+  ++  +   ++e+sv vL++g+Wpt++ +  v LP+el+ ++++f+
   Q: 516  LAKRLLLGKSASIDAEKSMISKLKTECGSQFTNKLEGMFKDIELSKEINESFKQSSQARIKLpSGIEMSVHVLTTGYWPTYPPMD-VRLPHELNVYQDIFK 615
           *****************************************************998888776489*****************988.*************** PP
   S: 500  efYlekhsgRkLqWqhtlgraelkaelkkgkyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvsskkqvlkkepeskeieeedlfsv 600
           efYl+k sgR+L Wq +lg++ lka + kgk+el+Vs fQ++vL++fn+ +k+s++++k++t+++++eLrrtlqsL+++k +vl+k p+++++e++d+f++
   Q: 616  EFYLSKYSGRRLMWQNSLGHCVLKADFPKGKKELAVSLFQTVVLMLFNDAQKLSFQDIKDSTGIEDKELRRTLQSLACGKVRVLQKLPKGRDVEDDDSFVF 716
           ***************************************************************************************************** PP
   S: 601  Nqef 604
           N+ f
   Q: 717  NEGF 720
           *987 PP

Organism

Theobroma cacao

Protein Sequence
(Fasta)

MSLPPTKRSL SNANSNATAS SSSSSSPHFQ PSMKKAKSQA VACSLDPNKN GLHHHHNQDD 60
NDVVFDPSSM ALDDDSKPDD ARAPAAANLS RKKATPPQPA KKLVIKLVKA KPTLPTNFEE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGATTATAA AAAGTGTTGA CAAGGTCATC GGGATCAAAA GTTTTTAAGT GATTATTATC 60
TGAACAAAAA ACAAAATTTT GAAGTTATTG TATCCAATTG GATTACTATT TCTTTCGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0031461--C:cullin-RING ubiquitin ligase complex
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000285	Aegilops tauschii	82.48	0.00e+00	1247.00
IUUC-Aml-002062	Ailuropoda melanoleuca	59.37	0.00e+00	861.00
IUUC-Atr-002727	Amborella trichopoda	88.80	0.00e+00	1276.00
IUUC-Apl-004157	Anas platyrhynchos	59.64	0.00e+00	864.00
IUUC-Aca-004430	Anolis carolinensis	59.83	0.00e+00	863.00
IUUC-Aly-006547	Arabidopsis lyrata	83.14	0.00e+00	1279.00
IUUC-Ath-006748	Arabidopsis thaliana	82.79	0.00e+00	1266.00
IUUC-Acl-008359	Aspergillus clavatus	36.04	4.00e-127	448.00
IUUC-Afl-008567	Aspergillus flavus	36.99	2.00e-135	476.00
IUUC-Afu-008833	Aspergillus fumigatus	36.68	7.00e-131	460.00
IUUC-Ani-009373	Aspergillus nidulans	37.01	7.00e-138	484.00
IUUC-Ang-009622	Aspergillus niger	39.31	3.00e-143	502.00
IUUC-Aor-010241	Aspergillus oryzae	36.93	7.00e-133	467.00
IUUC-Ate-010251	Aspergillus terreus	39.04	2.00e-142	499.00
IUUC-Ame-011580	Astyanax mexicanus	59.35	0.00e+00	853.00
IUUC-Bgr-012219	Blumeria graminis	35.83	2.00e-117	416.00
IUUC-Bta-013244	Bos taurus	59.37	0.00e+00	857.00
IUUC-Bci-013744	Botrytis cinerea	37.45	8.00e-127	447.00
IUUC-Bdi-014223	Brachypodium distachyon	81.71	0.00e+00	1258.00
IUUC-Bol-015666	Brassica oleracea	82.64	0.00e+00	1311.00
IUUC-Bra-017794	Brassica rapa	87.30	0.00e+00	1293.00
IUUC-Cja-019180	Callithrix jacchus	59.37	0.00e+00	861.00
IUUC-Cfa-021189	Canis familiaris	59.50	0.00e+00	860.00
IUUC-Cpo-021928	Cavia porcellus	59.37	0.00e+00	860.00
IUUC-Cre-022739	Chlamydomonas reinhardtii	54.78	0.00e+00	704.00
IUUC-Csa-023831	Chlorocebus sabaeus	59.37	0.00e+00	860.00
IUUC-Cho-024899	Choloepus hoffmanni	63.17	0.00e+00	647.00
IUUC-Cin-025727	Ciona intestinalis	55.12	0.00e+00	646.00
IUUC-Csv-026117	Ciona savignyi	45.88	0.00e+00	676.00
IUUC-Cgl-026761	Colletotrichum gloeosporioides	37.82	1.00e-130	459.00
IUUC-Cme-027355	Cyanidioschyzon merolae	33.82	4.00e-113	401.00
IUUC-Dre-027916	Danio rerio	59.40	0.00e+00	848.00
IUUC-Dno-028879	Dasypus novemcinctus	54.63	0.00e+00	773.00
IUUC-Dor-030698	Dipodomys ordii	57.98	0.00e+00	811.00
IUUC-Dse-031159	Dothistroma septosporum	35.48	1.00e-121	429.00
IUUC-Dme-031652	Drosophila melanogaster	55.22	0.00e+00	776.00
IUUC-Ete-033101	Echinops telfairi	54.98	0.00e+00	748.00
IUUC-Eca-033952	Equus caballus	59.18	0.00e+00	853.00
IUUC-Eeu-034767	Erinaceus europaeus	59.70	0.00e+00	805.00
IUUC-Fca-036211	Felis catus	59.15	0.00e+00	854.00
IUUC-Fal-037248	Ficedula albicollis	59.78	0.00e+00	863.00
IUUC-Fox-037854	Fusarium oxysporum	38.13	3.00e-124	438.00
IUUC-Fso-038138	Fusarium solani	37.11	5.00e-132	464.00
IUUC-Gmo-038754	Gadus morhua	58.73	0.00e+00	847.00
IUUC-Ggr-040003	Gaeumannomyces graminis	35.67	1.00e-102	367.00
IUUC-Gga-041002	Gallus gallus	59.78	0.00e+00	863.00
IUUC-Gac-041555	Gasterosteus aculeatus	58.71	0.00e+00	845.00
IUUC-Gma-043960	Glycine max	94.62	0.00e+00	1402.00
IUUC-Ggo-045468	Gorilla gorilla	58.42	0.00e+00	807.00
IUUC-Hsa-046848	Homo sapiens	59.37	0.00e+00	861.00
IUUC-Hvu-047510	Hordeum vulgare	77.58	0.00e+00	738.00
IUUC-Itr-048365	Ictidomys tridecemlineatus	59.50	0.00e+00	860.00
IUUC-Lch-049858	Latimeria chalumnae	59.64	0.00e+00	870.00
IUUC-Lpe-051446	Leersia perrieri	83.54	0.00e+00	1280.00
IUUC-Loc-051804	Lepisosteus oculatus	57.22	0.00e+00	829.00
IUUC-Lma-053080	Leptosphaeria maculans	34.45	1.00e-130	459.00
IUUC-Laf-053701	Loxodonta africana	59.42	0.00e+00	861.00
IUUC-Mcc-055538	Macaca mulatta	58.54	0.00e+00	843.00
IUUC-Meu-056492	Macropus eugenii	47.19	2.00e-82	299.00
IUUC-Mor-057102	Magnaporthe oryzae	35.31	4.00e-125	441.00
IUUC-Mpo-057342	Magnaporthe poae	36.63	1.00e-105	376.00
IUUC-Mtr-058660	Medicago truncatula	91.12	0.00e+00	1375.00
IUUC-Mla-058936	Melampsora laricipopulina	38.81	4.00e-111	394.00
IUUC-Mga-059754	Meleagris gallopavo	59.64	0.00e+00	866.00
IUUC-Mvi-060455	Microbotryum violaceum	43.57	5.00e-151	527.00
IUUC-Mmr-060870	Microcebus murinus	59.09	0.00e+00	853.00
IUUC-Mdo-062015	Monodelphis domestica	59.23	0.00e+00	857.00
IUUC-Mmu-063751	Mus musculus	59.23	0.00e+00	861.00
IUUC-Mac-064443	Musa acuminata	82.98	0.00e+00	1370.00
IUUC-Mpu-065903	Mustela putorius furo	59.37	0.00e+00	858.00
IUUC-Mlu-068213	Myotis lucifugus	59.37	0.00e+00	860.00
IUUC-Nfi-068363	Neosartorya fischeri	37.35	3.00e-134	471.00
IUUC-Ncr-068950	Neurospora crassa	36.83	5.00e-125	441.00
IUUC-Nle-069480	Nomascus leucogenys	59.37	0.00e+00	860.00
IUUC-Ont-071562	Oreochromis niloticus	57.14	0.00e+00	822.00
IUUC-Oan-073607	Ornithorhynchus anatinus	59.64	0.00e+00	859.00
IUUC-Ocu-074446	Oryctolagus cuniculus	59.37	0.00e+00	860.00
IUUC-Oba-075198	Oryza barthii	83.95	0.00e+00	1281.00
IUUC-Obr-076095	Oryza brachyantha	83.54	0.00e+00	1281.00
IUUC-Ogl-077032	Oryza glaberrima	83.95	0.00e+00	1283.00
IUUC-Ogu-078051	Oryza glumaepatula	83.95	0.00e+00	1283.00
IUUC-Oin-079399	Oryza indica	77.41	0.00e+00	1131.00
IUUC-Olo-080988	Oryza longistaminata	82.80	0.00e+00	1274.00
IUUC-Ome-081600	Oryza meridionalis	82.80	0.00e+00	1272.00
IUUC-Oni-082623	Oryza nivara	82.93	0.00e+00	1273.00
IUUC-Opu-083762	Oryza punctata	82.02	0.00e+00	1267.00
IUUC-Oru-084499	Oryza rufipogon	83.95	0.00e+00	1281.00
IUUC-Ola-087157	Oryzias latipes	58.71	0.00e+00	844.00
IUUC-Olu-087650	Ostreococcus lucimarinus	54.84	0.00e+00	721.00
IUUC-Oga-088416	Otolemur garnettii	58.54	0.00e+00	832.00
IUUC-Oar-090230	Ovis aries	59.37	0.00e+00	858.00
IUUC-Ptr-091153	Pan troglodytes	59.37	0.00e+00	860.00
IUUC-Pan-091729	Papio anubis	59.37	0.00e+00	860.00
IUUC-Psi-093773	Pelodiscus sinensis	59.51	0.00e+00	858.00
IUUC-Pma-094678	Petromyzon marinus	54.79	1.00e-178	619.00
IUUC-Pno-094946	Phaeosphaeria nodorum	35.48	2.00e-112	399.00
IUUC-Ppa-095688	Physcomitrella patens	81.56	0.00e+00	1232.00
IUUC-Pfo-096828	Poecilia formosa	59.07	0.00e+00	843.00
IUUC-Pab-097622	Pongo abelii	58.22	0.00e+00	822.00
IUUC-Pop-099751	Populus trichocarpa	85.17	0.00e+00	681.00
IUUC-Pca-100391	Procavia capensis	54.71	3.00e-180	624.00
IUUC-Ppe-101142	Prunus persica	91.61	0.00e+00	1462.00
IUUC-Pva-102995	Pteropus vampyrus	62.43	0.00e+00	639.00
IUUC-Pgr-103334	Puccinia graminis	36.69	3.00e-105	375.00
IUUC-Ptt-103903	Puccinia triticina	41.20	8.00e-96	344.00
IUUC-Pte-104167	Pyrenophora teres	35.20	4.00e-131	461.00
IUUC-Pyt-104736	Pyrenophora triticirepentis	35.42	1.00e-130	459.00
IUUC-Rno-106119	Rattus norvegicus	59.09	0.00e+00	857.00
IUUC-Sha-106958	Sarcophilus harrisii	59.37	0.00e+00	861.00
IUUC-Spo-108109	Schizosaccharomyces pombe	32.25	3.00e-106	378.00
IUUC-Ssl-108537	Sclerotinia sclerotiorum	37.10	6.00e-126	444.00
IUUC-Smo-108872	Selaginella moellendorffii	82.65	0.00e+00	1278.00
IUUC-Sit-110626	Setaria italica	83.83	0.00e+00	1280.00
IUUC-Sly-111497	Solanum lycopersicum	89.71	0.00e+00	1420.00
IUUC-Sar-113581	Sorex araneus	50.95	3.00e-172	597.00
IUUC-Sbi-113931	Sorghum bicolor	83.83	0.00e+00	1283.00
IUUC-Sre-114943	Sporisorium reilianum	38.86	6.00e-133	467.00
IUUC-Ssc-116133	Sus scrofa	57.94	0.00e+00	806.00
IUUC-Tgu-116462	Taeniopygia guttata	59.50	0.00e+00	856.00
IUUC-Tru-118299	Takifugu rubripes	59.23	0.00e+00	850.00
IUUC-Tsy-119517	Tarsius syrichta	68.57	2.00e-146	512.00
IUUC-Tni-119798	Tetraodon nigroviridis	56.25	0.00e+00	815.00
IUUC-Tre-121907	Trichoderma reesei	37.05	5.00e-128	451.00
IUUC-Tvi-122568	Trichoderma virens	36.86	1.00e-128	452.00
IUUC-Tae-123442	Triticum aestivum	81.57	0.00e+00	1254.00
IUUC-Tur-126032	Triticum urartu	83.10	0.00e+00	1249.00
IUUC-Tme-127162	Tuber melanosporum	40.34	9.00e-140	490.00
IUUC-Tbe-127658	Tupaia belangeri	58.44	0.00e+00	823.00
IUUC-Ttr-128326	Tursiops truncatus	55.23	0.00e+00	700.00
IUUC-Uma-129531	Ustilago maydis	37.89	5.00e-114	404.00
IUUC-Vda-129701	Verticillium dahliae	38.07	4.00e-138	484.00
IUUC-Vpa-130217	Vicugna pacos	53.44	0.00e+00	739.00
IUUC-Vvi-131133	Vitis vinifera	90.04	0.00e+00	1431.00
IUUC-Xtr-132761	Xenopus tropicalis	58.10	0.00e+00	822.00
IUUC-Xma-134149	Xiphophorus maculatus	58.87	0.00e+00	850.00
IUUC-Zma-135529	Zea mays	83.42	0.00e+00	1279.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence