iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gma-043146

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ribosome biogenesis protein WDR12 homolog

Genbank Nucleotide ID

CM000852

Gene Name

LOC100789690; GLYMA_19G029400

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GLYMA19G03590	GLYMA19G03590.1	GLYMA19G03590.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-31	108.1	359	393
UBD/Beta-Prp	1.30e-40	141.1	264	426

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtg 33
           Ht++++++++  ++  +l+s+s+Dg++++WDlrt 
   Q: 359  HTSWISACKWhdQSwFHLLSASYDGKVMLWDLRTA 393
           **********9744577***************986 PP

UBD/Beta-Prp

   S: 84   gkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl...ktgkllr 173
           g+ + tl gh++ v ++ + + ++++ s+s+d  ir wd+etg+ l +++    +v nc+ + ++g  l+++G+ D ++r+Wd     t   + 
   Q: 264  GEAFTTLVGHTQCVSAVVWPQ-QESIYSASWDHSIRKWDVETGKNLTDLF--CGKVLNCLDIGGEGsALIAAGGSDPVIRIWDPrkpGTSAPVF 354
           78899***********99988.99**********************7555..5578****************************8777788888 PP
   S: 174  tltgghtdsvyslsfdsng.kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsi 246
           ++++ ht+ +   ++++++ ++l+s+s+dg+v lwdl+t   +   + h+d v+s + + +++ ++sg++D  +
   Q: 355  QFSS-HTSWISACKWHDQSwFHLLSASYDGKVMLWDLRTAWPLSVIESHSDKVLSADWW-KSNSVISGGADSKL 426
           8899.************99****************************************.9*********9876 PP

Organism

Glycine max

Functional Description
(View)

Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.

Protein Sequence
(Fasta)

MNMNEESVEG SARRIQVRFV TKLGEPYKVP TTAIAIPADL ARFGLSSLVN ALLQSNDADH 60
QLEPFDFLID GEFVRMSLEQ FLLAKGISAE RILEIEYTRA VAPRKEEDPS LHDDWVSAVD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTCGACAAA ATTTGGGGGT ATTAACGTAA TTTGCTCTAA ATTCTAAAAC CCATGGCAAC 60
TGAACTCGCA GGTTGAGAAC CGTTAAACCC TAGCTTCTTC TTCCTCTTCC TCTTCGCTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR012972--NLE
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR028599--WDR12/Ytm1

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08154--NLE
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0043021--F:ribonucleoprotein complex binding
GO:0000460--P:maturation of 5.8S rRNA
GO:0000466--P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000470--P:maturation of LSU-rRNA
GO:0000463--P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

KEGG

gmx:100789690

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001997	Ailuropoda melanoleuca	36.63	2.00e-61	229.00
IUUC-Apl-003981	Anas platyrhynchos	36.56	7.00e-60	224.00
IUUC-Aca-004370	Anolis carolinensis	35.41	5.00e-66	244.00
IUUC-Aly-006455	Arabidopsis lyrata	70.11	0.00e+00	647.00
IUUC-Ame-011432	Astyanax mexicanus	36.14	1.00e-69	256.00
IUUC-Bta-012829	Bos taurus	36.69	2.00e-64	239.00
IUUC-Cja-019468	Callithrix jacchus	37.17	1.00e-61	230.00
IUUC-Cfa-020471	Canis familiaris	35.25	2.00e-59	223.00
IUUC-Cpo-022260	Cavia porcellus	36.93	6.00e-63	234.00
IUUC-Csa-023989	Chlorocebus sabaeus	36.93	1.00e-61	230.00
IUUC-Dre-027907	Danio rerio	36.14	3.00e-69	255.00
IUUC-Dno-029225	Dasypus novemcinctus	36.90	8.00e-64	237.00
IUUC-Dor-031082	Dipodomys ordii	32.53	2.00e-28	119.00
IUUC-Ete-032247	Echinops telfairi	34.05	8.00e-56	211.00
IUUC-Eca-034285	Equus caballus	36.21	1.00e-62	233.00
IUUC-Eeu-035322	Erinaceus europaeus	32.84	5.00e-52	198.00
IUUC-Fca-036114	Felis catus	36.21	1.00e-62	233.00
IUUC-Gmo-039040	Gadus morhua	36.71	7.00e-73	267.00
IUUC-Gga-040610	Gallus gallus	35.34	2.00e-63	236.00
IUUC-Gac-042117	Gasterosteus aculeatus	36.45	2.00e-68	252.00
IUUC-Ggo-045179	Gorilla gorilla	36.93	2.00e-62	233.00
IUUC-Hsa-046114	Homo sapiens	36.93	7.00e-62	231.00
IUUC-Itr-048275	Ictidomys tridecemlineatus	36.69	9.00e-64	237.00
IUUC-Lch-050655	Latimeria chalumnae	33.62	3.00e-48	185.00
IUUC-Laf-053993	Loxodonta africana	35.73	5.00e-63	234.00
IUUC-Mga-059745	Meleagris gallopavo	35.64	4.00e-61	228.00
IUUC-Mdo-062257	Monodelphis domestica	35.34	2.00e-65	243.00
IUUC-Mmu-063546	Mus musculus	35.61	4.00e-64	238.00
IUUC-Mpu-066284	Mustela putorius furo	36.21	3.00e-63	236.00
IUUC-Mlu-067241	Myotis lucifugus	37.17	3.00e-64	238.00
IUUC-Nle-068981	Nomascus leucogenys	36.54	2.00e-60	226.00
IUUC-Opr-071218	Ochotona princeps	34.41	3.00e-57	215.00
IUUC-Ont-071646	Oreochromis niloticus	35.89	4.00e-65	241.00
IUUC-Oan-073453	Ornithorhynchus anatinus	36.45	4.00e-73	268.00
IUUC-Ocu-074008	Oryctolagus cuniculus	36.69	3.00e-64	239.00
IUUC-Ola-087420	Oryzias latipes	36.69	4.00e-70	258.00
IUUC-Oga-088264	Otolemur garnettii	35.58	2.00e-60	226.00
IUUC-Oar-089335	Ovis aries	36.45	5.00e-64	238.00
IUUC-Ptr-091320	Pan troglodytes	36.93	7.00e-62	231.00
IUUC-Pan-092833	Papio anubis	37.17	5.00e-62	231.00
IUUC-Psi-093504	Pelodiscus sinensis	34.84	2.00e-61	229.00
IUUC-Pfo-096337	Poecilia formosa	36.45	1.00e-69	256.00
IUUC-Pab-097571	Pongo abelii	36.69	1.00e-61	230.00
IUUC-Pca-100394	Procavia capensis	34.90	3.00e-52	199.00
IUUC-Pva-102921	Pteropus vampyrus	33.48	2.00e-26	113.00
IUUC-Rno-105114	Rattus norvegicus	36.43	8.00e-64	237.00
IUUC-Stu-112169	Solanum tuberosum	70.32	0.00e+00	629.00
IUUC-Sar-113596	Sorex araneus	33.51	1.00e-46	181.00
IUUC-Sre-115002	Sporisorium reilianum	25.26	7.00e-18	85.50
IUUC-Ssc-116066	Sus scrofa	36.21	2.00e-63	236.00
IUUC-Tgu-117048	Taeniopygia guttata	36.02	8.00e-58	217.00
IUUC-Tsy-119573	Tarsius syrichta	26.80	1.00e-21	97.40
IUUC-Tni-119820	Tetraodon nigroviridis	36.78	5.00e-66	244.00
IUUC-Tca-121605	Theobroma cacao	73.79	0.00e+00	678.00
IUUC-Tme-126900	Tuber melanosporum	33.71	2.00e-55	210.00
IUUC-Ttr-129041	Tursiops truncatus	31.65	1.00e-46	181.00
IUUC-Uma-129628	Ustilago maydis	27.94	5.00e-10	59.30
IUUC-Vpa-130260	Vicugna pacos	36.45	6.00e-64	238.00
IUUC-Xtr-132083	Xenopus tropicalis	37.26	3.00e-67	248.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence