iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ppe-102012

Ensembl Protein ID

EMJ09325

UniProt Accession

M5WR73; M5WR73_PRUPE

Genbank Protein ID

EMJ09325.1

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

KB639090

Gene Name

PRUPE_ppa000563mg

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PRUPE_ppa000563mg	EMJ09325	EMJ09325

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.80e-167	558.2	490	977

Active Site

Position(s)	Description	Evidence
671	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveahees 96
           YD Qi ++G++ q+kl+ +k++ vG g+lGcE+lKnL+l+Gv     g++t++D+d +e+snl+rqFLfr++++g+ K+ vaa a++ +n   n+ea +++
   Q: 490  YDAQISVFGAKLQKKLEDSKMFTVGSGALGCEFLKNLALMGVscgkeGKLTITDDDVIEKSNLSRQFLFRDWNIGQAKSTVAASAAALINGRLNIEALQNR 590
           ***************************************************************************************************** PP
   S: 97   iteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa.... 190
            ++++e+++   F +++dvV++aldn+ ar++++++cl+ ++pl+esgtlG + +++ ++++lte y +s+dpp+k++P+ct+ ++p +++h+++wa    
   Q: 591  ASPDTENVFddtFWENLDVVINALDNVNARLYIDQRCLYFQKPLLESGTLGAKCNTQMVVPHLTENYGASRDPPEKQAPMCTVHSFPHNIDHCLTWArsef 691
           *******99******************************************************************************************** PP
   S: 191  ........vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtkskspfwv......... 274
                   + +n +l + a+ ++   +   ++ ++ ++ v + l +e+ e+f+++i++a+ +f+ ++ n +kql+  f+ d  t+s++pfw+         
   Q: 692  egllekvpAEVNAYLTNPAEYTTAMMNAGDAQARNNLESVIECLDKERCETFQDCISWARLKFEDYFVNRVKQLTYTFPEDAKTSSGTPFWSapkrfprpl 792
           ****999989999999999999999999999999999999999999******************************************************* PP
   S: 275  .................................sfcsnaealq.......vpekvekdeevvkasap.............lylllralerfekk..kgrkp 320
                                            s+ ++a+a++       +    +kd ++v+++++             +  l+ +le+ +++  +  k+
   Q: 793  qfsvddlshlqfimgasilraetfnipipdwvkSHTKFADAVNkvivpdfQ---PKKDVKIVTDEKAtnvlpasiddavvINELIVKLEKCKEQlpPAFKM 890
           *********************************888888888866644432...2333333333333344666677888999999999988887557899* PP
   S: 321  gelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           + ++fekddd   ++d+++ +an+ra ++gi++ +d+ + k iag+iipaiat +a   Gl+++E++Kv++g  k e ++n+f ++a+
   Q: 891  NPIQFEKDDDTnyHMDVIAGFANMRARNYGIPE-VDKLKAKFIAGRIIPAIATSTALATGLVCLELYKVLDGghKLEDYRNTFANLAL 977
           *********************************.*************************************************99875 PP

Organism

Prunus persica

Protein Sequence
(Fasta)

MRFWCFGSSS HYMLPRKREV GGEVVVKEEG EPNYSTESPI KKLRAAANTD DSKSNDYKNN 60
TTIDNSNNSS KDVKVPIMAL GNGNSNDIDE DLHSRQLAVY GRETMRRLFA SNILVSGLQG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGGTTTT GGTGTTTCGG CAGTTCATCG CACTATATGC TTCCTAGAAA GAGAGAAGTG 60
GGCGGAGAGG TTGTAGTAAA AGAAGAAGGG GAACCAAACT ACTCCACCGA ATCTCCGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

KEGG

pper:PRUPE_ppa000563mg

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000456	Aegilops tauschii	78.90	0.00e+00	1669.00
IUUC-Aml-001311	Ailuropoda melanoleuca	43.36	0.00e+00	882.00
IUUC-Atr-002684	Amborella trichopoda	75.83	0.00e+00	1697.00
IUUC-Apl-004158	Anas platyrhynchos	39.10	0.00e+00	668.00
IUUC-Aca-004620	Anolis carolinensis	44.16	0.00e+00	867.00
IUUC-Aly-005418	Arabidopsis lyrata	80.16	0.00e+00	1749.00
IUUC-Afl-008455	Aspergillus flavus	45.12	0.00e+00	792.00
IUUC-Afu-009065	Aspergillus fumigatus	45.16	0.00e+00	843.00
IUUC-Aor-010007	Aspergillus oryzae	45.12	0.00e+00	793.00
IUUC-Ate-010466	Aspergillus terreus	44.26	0.00e+00	838.00
IUUC-Ame-010933	Astyanax mexicanus	43.00	0.00e+00	827.00
IUUC-Bgr-012281	Blumeria graminis	44.55	0.00e+00	837.00
IUUC-Bci-013721	Botrytis cinerea	45.06	0.00e+00	798.00
IUUC-Bdi-014843	Brachypodium distachyon	75.83	0.00e+00	1634.00
IUUC-Bol-015880	Brassica oleracea	80.16	0.00e+00	1755.00
IUUC-Bra-017252	Brassica rapa	76.68	0.00e+00	1760.00
IUUC-Cel-018260	Caenorhabditis elegans	36.43	0.00e+00	650.00
IUUC-Cja-019152	Callithrix jacchus	43.38	0.00e+00	885.00
IUUC-Cfa-020622	Canis familiaris	42.13	0.00e+00	837.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	57.79	0.00e+00	1169.00
IUUC-Csa-023780	Chlorocebus sabaeus	43.43	0.00e+00	884.00
IUUC-Cho-024682	Choloepus hoffmanni	35.79	5.00e-102	365.00
IUUC-Cin-025790	Ciona intestinalis	43.90	0.00e+00	870.00
IUUC-Csv-026084	Ciona savignyi	41.84	0.00e+00	842.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	45.68	0.00e+00	884.00
IUUC-Cne-026960	Cryptococcus neoformans	45.54	0.00e+00	865.00
IUUC-Cme-027290	Cyanidioschyzon merolae	38.28	0.00e+00	682.00
IUUC-Dre-028149	Danio rerio	43.56	0.00e+00	855.00
IUUC-Dno-028884	Dasypus novemcinctus	43.15	0.00e+00	884.00
IUUC-Dor-030229	Dipodomys ordii	41.57	0.00e+00	835.00
IUUC-Dse-031524	Dothistroma septosporum	43.43	0.00e+00	846.00
IUUC-Dme-032045	Drosophila melanogaster	43.18	0.00e+00	830.00
IUUC-Ete-033124	Echinops telfairi	39.12	8.00e-130	457.00
IUUC-Eca-033330	Equus caballus	43.06	0.00e+00	877.00
IUUC-Eeu-035323	Erinaceus europaeus	39.66	4.00e-147	514.00
IUUC-Fca-036255	Felis catus	43.15	0.00e+00	873.00
IUUC-Fal-036848	Ficedula albicollis	38.60	0.00e+00	679.00
IUUC-Fox-038007	Fusarium oxysporum	47.96	3.00e-135	474.00
IUUC-Fso-038339	Fusarium solani	46.35	0.00e+00	829.00
IUUC-Gmo-039338	Gadus morhua	42.40	0.00e+00	835.00
IUUC-Ggr-039823	Gaeumannomyces graminis	44.74	0.00e+00	875.00
IUUC-Gga-040747	Gallus gallus	39.04	0.00e+00	668.00
IUUC-Gac-041773	Gasterosteus aculeatus	42.55	0.00e+00	827.00
IUUC-Gma-043198	Glycine max	80.88	0.00e+00	1788.00
IUUC-Ggo-045336	Gorilla gorilla	43.43	0.00e+00	868.00
IUUC-Hsa-045982	Homo sapiens	43.43	0.00e+00	868.00
IUUC-Hvu-047418	Hordeum vulgare	77.90	0.00e+00	1647.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	43.34	0.00e+00	882.00
IUUC-Kpa-049112	Komagataella pastoris	44.58	0.00e+00	855.00
IUUC-Lch-050371	Latimeria chalumnae	44.09	0.00e+00	881.00
IUUC-Lpe-051299	Leersia perrieri	75.81	0.00e+00	1622.00
IUUC-Loc-052936	Lepisosteus oculatus	43.33	0.00e+00	863.00
IUUC-Lma-053315	Leptosphaeria maculans	44.45	0.00e+00	881.00
IUUC-Laf-053948	Loxodonta africana	43.12	0.00e+00	863.00
IUUC-Mcc-055843	Macaca mulatta	43.43	0.00e+00	885.00
IUUC-Meu-056258	Macropus eugenii	44.54	0.00e+00	874.00
IUUC-Mor-057269	Magnaporthe oryzae	44.51	0.00e+00	848.00
IUUC-Mpo-057435	Magnaporthe poae	44.87	0.00e+00	851.00
IUUC-Mtr-058572	Medicago truncatula	80.22	0.00e+00	1747.00
IUUC-Mga-059721	Meleagris gallopavo	39.37	0.00e+00	648.00
IUUC-Mvi-060437	Microbotryum violaceum	42.42	0.00e+00	803.00
IUUC-Mmr-061405	Microcebus murinus	42.42	0.00e+00	843.00
IUUC-Mdo-062032	Monodelphis domestica	43.78	0.00e+00	852.00
IUUC-Mmu-063280	Mus musculus	42.72	0.00e+00	859.00
IUUC-Mac-065505	Musa acuminata	75.74	0.00e+00	1675.00
IUUC-Mpu-066409	Mustela putorius furo	43.52	0.00e+00	891.00
IUUC-Mlu-067217	Myotis lucifugus	43.34	0.00e+00	877.00
IUUC-Nfi-068407	Neosartorya fischeri	44.81	0.00e+00	824.00
IUUC-Ncr-068698	Neurospora crassa	45.42	0.00e+00	853.00
IUUC-Nle-070072	Nomascus leucogenys	41.02	0.00e+00	793.00
IUUC-Opr-070715	Ochotona princeps	36.22	9.00e-157	546.00
IUUC-Ont-071671	Oreochromis niloticus	43.47	0.00e+00	847.00
IUUC-Oan-073268	Ornithorhynchus anatinus	39.39	0.00e+00	628.00
IUUC-Ocu-074544	Oryctolagus cuniculus	44.54	0.00e+00	886.00
IUUC-Oba-075120	Oryza barthii	75.87	0.00e+00	1643.00
IUUC-Obr-076557	Oryza brachyantha	79.43	0.00e+00	1641.00
IUUC-Ogl-077887	Oryza glaberrima	79.33	0.00e+00	1637.00
IUUC-Ogu-078305	Oryza glumaepatula	76.45	0.00e+00	1622.00
IUUC-Oin-079370	Oryza indica	73.75	0.00e+00	1614.00
IUUC-Olo-081089	Oryza longistaminata	76.64	0.00e+00	1627.00
IUUC-Ome-081942	Oryza meridionalis	76.29	0.00e+00	1648.00
IUUC-Oni-082365	Oryza nivara	76.15	0.00e+00	1649.00
IUUC-Opu-083301	Oryza punctata	79.72	0.00e+00	1645.00
IUUC-Oru-084469	Oryza rufipogon	76.64	0.00e+00	1625.00
IUUC-Osa-085949	Oryza sativa	79.23	0.00e+00	1659.00
IUUC-Ola-087002	Oryzias latipes	43.54	0.00e+00	855.00
IUUC-Olu-087687	Ostreococcus lucimarinus	57.44	0.00e+00	1130.00
IUUC-Oga-088594	Otolemur garnettii	44.69	0.00e+00	863.00
IUUC-Ptr-090609	Pan troglodytes	38.99	0.00e+00	680.00
IUUC-Pan-092114	Papio anubis	43.43	0.00e+00	885.00
IUUC-Psi-093489	Pelodiscus sinensis	38.22	0.00e+00	662.00
IUUC-Pma-094214	Petromyzon marinus	46.20	3.00e-34	137.00
IUUC-Pno-095154	Phaeosphaeria nodorum	44.15	0.00e+00	860.00
IUUC-Ppa-095227	Physcomitrella patens	70.98	0.00e+00	1515.00
IUUC-Pab-097861	Pongo abelii	43.43	0.00e+00	857.00
IUUC-Pca-100347	Procavia capensis	41.76	0.00e+00	705.00
IUUC-Pva-102584	Pteropus vampyrus	43.43	0.00e+00	911.00
IUUC-Pte-104200	Pyrenophora teres	45.89	0.00e+00	895.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	45.28	0.00e+00	887.00
IUUC-Rno-105462	Rattus norvegicus	44.05	0.00e+00	863.00
IUUC-Sce-106245	Saccharomyces cerevisiae	44.29	0.00e+00	857.00
IUUC-Sha-107142	Sarcophilus harrisii	44.54	0.00e+00	876.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	43.34	0.00e+00	837.00
IUUC-Spo-108034	Schizosaccharomyces pombe	43.85	0.00e+00	833.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	43.77	0.00e+00	806.00
IUUC-Smo-108912	Selaginella moellendorffii	72.48	0.00e+00	1526.00
IUUC-Sit-110281	Setaria italica	80.97	0.00e+00	1671.00
IUUC-Sly-110914	Solanum lycopersicum	82.91	0.00e+00	1792.00
IUUC-Stu-112109	Solanum tuberosum	83.30	0.00e+00	1810.00
IUUC-Sar-113737	Sorex araneus	43.26	0.00e+00	873.00
IUUC-Sbi-114089	Sorghum bicolor	79.82	0.00e+00	1680.00
IUUC-Sre-115148	Sporisorium reilianum	46.15	0.00e+00	822.00
IUUC-Ssc-115777	Sus scrofa	43.15	0.00e+00	873.00
IUUC-Tgu-116565	Taeniopygia guttata	38.48	0.00e+00	672.00
IUUC-Tru-118742	Takifugu rubripes	43.87	0.00e+00	810.00
IUUC-Tsy-119436	Tarsius syrichta	34.60	2.00e-160	558.00
IUUC-Tni-120401	Tetraodon nigroviridis	43.58	0.00e+00	810.00
IUUC-Tca-121436	Theobroma cacao	80.96	0.00e+00	1829.00
IUUC-Tre-122009	Trichoderma reesei	47.17	0.00e+00	841.00
IUUC-Tvi-122259	Trichoderma virens	46.27	0.00e+00	821.00
IUUC-Tae-125113	Triticum aestivum	79.70	0.00e+00	1615.00
IUUC-Tur-126330	Triticum urartu	78.90	0.00e+00	1672.00
IUUC-Tme-127055	Tuber melanosporum	43.79	0.00e+00	803.00
IUUC-Tbe-127587	Tupaia belangeri	40.00	3.00e-133	468.00
IUUC-Ttr-128331	Tursiops truncatus	43.52	0.00e+00	872.00
IUUC-Uma-129387	Ustilago maydis	45.49	0.00e+00	814.00
IUUC-Vda-129977	Verticillium dahliae	47.17	0.00e+00	815.00
IUUC-Vpa-130716	Vicugna pacos	38.57	0.00e+00	664.00
IUUC-Vvi-131026	Vitis vinifera	83.14	0.00e+00	1871.00
IUUC-Xtr-132026	Xenopus tropicalis	38.38	0.00e+00	656.00
IUUC-Yli-134547	Yarrowia lipolytica	44.51	0.00e+00	860.00
IUUC-Zma-135758	Zea mays	76.17	0.00e+00	1655.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence