iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-007655

UUCD1 version

UUC-ArT-01457

Ensembl Protein ID

AT3G47990.1

UniProt Accession

Q8GYT9; Q9SU62; SIS3_ARATH

Genbank Protein ID

CAB41140.1; AEE78354.1; BAC42060.1

Protein Name

E3 ubiquitin-protein ligase SIS3; Protein SUGAR INSENSITIVE 3; RING-type E3 ubiquitin transferase SIS3

Genbank Nucleotide ID

AL049658; CP002686; AK117391

Gene Name

SIS3; At3g47990; T17F15.140

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT3G47990	AT3G47990.2	AT3G47990.2
AT3G47990	AT3G47990.1	AT3G47990.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	20147494

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	1.70e-06	29.3	235	276

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCle+f   ++++ lpC H fh +C+ +w       + + +CP Cr
   Q: 235  CLICLEEFhiGHEVRGLPCAHNFHVECIDQW------LRLNVKCPRCR 276
           ******9988666******************......**********8 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

E3 ubiquitin protein ligase that acts as positive regulator of sugar signaling during early seedling development. Possesses E3 ligase activity in vitro.

Protein Sequence
(Fasta)

MAMRGVDFKW YDGFFLSMLA TSVIIVAVNW NRYRACEYPL HIWIVVDYTT VFIFRVFMFV 60
DNGLASGLGL DFGSQQRNAM FCGRVVVLSV LSLLLYPFLW AWTVIGTQWF TKSKTCLPEE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTTTTCTAT TTAAATAATA TTTTTAACAT GACTGAAAAA TGTTGAACGC ATCAGAAGTG 60
ACCAAATCGT GAATTTTAAC TTGTTCGTCA GCCAGAAGTT TCCGTTTCTC TTTAGTTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0732--Signal
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0010182--P:sugar mediated signaling pathway

KEGG

ath:AT3G47990

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000667	Aegilops tauschii	79.59	1.00e-140	493.00
IUUC-Atr-002648	Amborella trichopoda	72.83	3.00e-146	510.00
IUUC-Aly-006490	Arabidopsis lyrata	98.04	0.00e+00	709.00
IUUC-Bdi-014759	Brachypodium distachyon	70.38	6.00e-130	456.00
IUUC-Bol-015136	Brassica oleracea	89.42	0.00e+00	645.00
IUUC-Bra-018024	Brassica rapa	84.97	1.00e-173	601.00
IUUC-Gma-042879	Glycine max	74.93	2.00e-159	554.00
IUUC-Hvu-047589	Hordeum vulgare	78.23	5.00e-63	231.00
IUUC-Lpe-051403	Leersia perrieri	63.45	3.00e-99	353.00
IUUC-Mtr-058746	Medicago truncatula	75.41	3.00e-162	563.00
IUUC-Mac-064833	Musa acuminata	76.35	8.00e-152	529.00
IUUC-Oba-075099	Oryza barthii	76.85	1.00e-143	501.00
IUUC-Obr-076541	Oryza brachyantha	74.85	3.00e-144	504.00
IUUC-Ogl-077544	Oryza glaberrima	76.85	1.00e-143	502.00
IUUC-Ogu-078123	Oryza glumaepatula	72.22	7.00e-131	459.00
IUUC-Oin-079313	Oryza indica	75.80	6.00e-137	479.00
IUUC-Olo-080383	Oryza longistaminata	54.63	3.00e-91	327.00
IUUC-Ome-081106	Oryza meridionalis	65.78	2.00e-111	394.00
IUUC-Oni-082730	Oryza nivara	75.90	4.00e-146	510.00
IUUC-Opu-083224	Oryza punctata	72.57	3.00e-144	503.00
IUUC-Oru-085150	Oryza rufipogon	76.19	4.00e-117	414.00
IUUC-Osa-086306	Oryza sativa	76.54	2.00e-143	501.00
IUUC-Ppa-095217	Physcomitrella patens	46.50	1.00e-69	255.00
IUUC-Pop-099421	Populus trichocarpa	73.80	2.00e-145	508.00
IUUC-Ppe-101399	Prunus persica	74.07	1.00e-134	471.00
IUUC-Smo-109501	Selaginella moellendorffii	65.08	1.00e-111	395.00
IUUC-Sit-109685	Setaria italica	73.06	2.00e-146	511.00
IUUC-Sly-111730	Solanum lycopersicum	75.72	4.00e-155	540.00
IUUC-Stu-112358	Solanum tuberosum	72.75	3.00e-152	530.00
IUUC-Sbi-114646	Sorghum bicolor	72.96	5.00e-144	503.00
IUUC-Tni-119836	Tetraodon nigroviridis	38.75	1.00e-11	63.50
IUUC-Tca-121643	Theobroma cacao	76.34	2.00e-160	557.00
IUUC-Tae-123724	Triticum aestivum	73.73	1.00e-141	494.00
IUUC-Tur-126639	Triticum urartu	77.73	9.00e-113	400.00
IUUC-Vvi-131627	Vitis vinifera	67.10	2.00e-147	514.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence