iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mtr-058037

Ensembl Protein ID

AES86542

UniProt Accession

G7JGU9; G7JGU9_MEDTR

Genbank Protein ID

AES86542.2

Protein Name

Topless-like protein

Genbank Nucleotide ID

CM001220

Gene Name

MTR_4g009840

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MTR_4g009840	AES86542	AES86542

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-21	76.8	462	496
UBD/Beta-Prp	4.20e-56	191.8	420	757

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tl.lvsGsdDgtikvWDlrt 32
           H ++v++laf  ++  l +++++dD+tikvWD  +
   Q: 462  HVGGVNDLAFshPNkQLcVITCGDDKTIKVWDAVS 496
           999*******99764334699***********765 PP

UBD/Beta-Prp

   S: 12   vitcvkfspdksllatgsrdgtikvwdvttgkllrsl...sgheaevtavkfspdgk..ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..s 105
            ++ v +spd+ l+ +++ ++ +++++++tg+ +r+      h ++v+++ fs+  k    +t+++D+tikvwd  +g   +t++ghe+ v+s+  +   +
   Q: 420  SVNRVIWSPDGALFGVAYSRHIVQIYSYHTGDDVRQHleiDAHVGGVNDLAFSHPNKqlCVITCGDDKTIKVWDAVSGAKQYTFEGHEAPVYSVCPHYkeN 520
           5667889************************99654323389***********99888999********************************85554438 PP
   S: 106  gdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGsl..Dr..tvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldg 202
            +++ s+  d  i+ w  ++     + +++  ++ ++++++ dg  l+s+++  D+   +  W+ + g + rt +g  ++s   ++fd ++++++++++d 
   Q: 521  IQFIFSTALDGKIKAWLYDNLGSRVDYDAPG-RWCTTMAYSADGTRLFSCGTskDGesSIVEWNESEGAVKRTYQGFRKRSMGVVQFDTTKNRFLAAGDDF 620
           8***************999988777566665.5999999***9*888888652254335777*************************************** PP
   S: 203  tvklwdlqtgecvrtlnghtdnvks..vrfspnderlvsgssDgsiriW.dlrsgdllktlqlhn.................................ssv 267
           ++k+wd+ + + + t+ +    + s  +rf +++++l++ + D+ i+i  + +   ll+tl++                                   ssv
   Q: 621  SIKFWDMDNIQLLTTVDADGGLPASprIRFNKDGTLLAVSANDNGIKIVaNADGIRLLRTLENNSmydasrasemakptinsmssaaaatsaalaeraSSV 721
           ****************999987775338888*****************77777777777777777776666777777777666666666666666666666 PP
   S: 268  isvavlsfgdnvl......vlgsedskvniwklkkn 297
            ++a+++ + + +      ++ ++++k +iwkl+++
   Q: 722  AAIAGMNGDTRSMgdvkprISEEANDKSKIWKLTEI 757
           66666555555558999989999999******9986 PP

Organism

Medicago truncatula

Protein Sequence
(Fasta)

MSSLSRELVF LILQFLDEEK FKETVHKLEQ ESGFFFNMKY FEDEVHNGNW DEVEKYLSGF 60
TKVDDNRYSM KIFFEIRKQK YLEALDKHDR SKAVEILVKD LKVFATFNEE LFKEITQLLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAATGTCCCC TTCTCTCTCT CTCTCTCTCT ATAAATATAG ATTTAGAGGA GTTTCTAGAG 60
AGAGAAAGTG TAGATTAGTC CATATCTGTG AGGAGAGAGA AAGTGTTTAA GAATCTTGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR006595--CTLH_C
IPR006594--LisH
IPR011047--Quinoprotein_ADH-like_supfam
IPR027728--Topless_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50897--CTLH
PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00668--CTLH
SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0006355--P:regulation of transcription, DNA-templated

KEGG

mtr:MTR_4g009840

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000565	Aegilops tauschii	79.06	0.00e+00	1805.00
IUUC-Aly-005472	Arabidopsis lyrata	82.70	0.00e+00	1875.00
IUUC-Ath-007640	Arabidopsis thaliana	81.93	0.00e+00	1873.00
IUUC-Bdi-014914	Brachypodium distachyon	78.71	0.00e+00	1768.00
IUUC-Bol-016225	Brassica oleracea	82.65	0.00e+00	1892.00
IUUC-Bra-016893	Brassica rapa	81.23	0.00e+00	1853.00
IUUC-Gma-044036	Glycine max	92.98	0.00e+00	2071.00
IUUC-Hvu-047688	Hordeum vulgare	80.54	0.00e+00	1716.00
IUUC-Lpe-051514	Leersia perrieri	77.39	0.00e+00	1703.00
IUUC-Mac-065382	Musa acuminata	79.88	0.00e+00	1822.00
IUUC-Oba-075912	Oryza barthii	80.75	0.00e+00	1789.00
IUUC-Obr-076921	Oryza brachyantha	79.55	0.00e+00	1783.00
IUUC-Ogl-077334	Oryza glaberrima	79.91	0.00e+00	1793.00
IUUC-Ogu-078494	Oryza glumaepatula	79.91	0.00e+00	1793.00
IUUC-Oin-079720	Oryza indica	78.68	0.00e+00	1784.00
IUUC-Olo-081034	Oryza longistaminata	77.69	0.00e+00	1766.00
IUUC-Ome-081778	Oryza meridionalis	79.83	0.00e+00	1795.00
IUUC-Oni-082412	Oryza nivara	80.75	0.00e+00	1789.00
IUUC-Opu-083406	Oryza punctata	79.27	0.00e+00	1744.00
IUUC-Oru-084328	Oryza rufipogon	80.75	0.00e+00	1791.00
IUUC-Osa-085765	Oryza sativa	79.91	0.00e+00	1793.00
IUUC-Ppa-095814	Physcomitrella patens	70.15	0.00e+00	1561.00
IUUC-Pop-098876	Populus trichocarpa	84.00	0.00e+00	1923.00
IUUC-Ppe-101370	Prunus persica	88.20	0.00e+00	2031.00
IUUC-Sit-110288	Setaria italica	79.49	0.00e+00	1772.00
IUUC-Sly-111739	Solanum lycopersicum	84.80	0.00e+00	1918.00
IUUC-Sbi-114078	Sorghum bicolor	79.51	0.00e+00	1760.00
IUUC-Tca-121628	Theobroma cacao	87.01	0.00e+00	1973.00
IUUC-Tae-125600	Triticum aestivum	79.74	0.00e+00	1807.00
IUUC-Tur-126412	Triticum urartu	78.86	0.00e+00	1799.00
IUUC-Vvi-131079	Vitis vinifera	86.99	0.00e+00	1958.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence