iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074026

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02022748

Gene Name

KLHL8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000002115.3	ENSOCUT00000002113.3	ENSOCUP00000001821.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	6.30e-17	61.8	66	131
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.00e-09	37.6	165	196

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l+vg + +++h++vLa   ++F+a+fl+e+ e k +  +ei+d + +  ++l+kF+Y+++l++
   Q: 66   CDVTLKVGSKLISCHRLVLACVIPYFRAMFLSEMAEAK-QTLIEIRDFDGDTIEDLVKFVYSSRLTL 131
           9************************************9.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Ncl++++fA+ ++  dL+d a+ +++ hF+
   Q: 165  PSNCLAVRAFAESHNRIDLMDMADQYACEHFP 196
           89*****************************6 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MASESVNGKQ ARNHFTKGKK QQQQQIKNRS SVGDGDGEDS FIFEANEAWK DFHGSLLRFY 60
ENGELCDVTL KVGSKLISCH RLVLACVIPY FRAMFLSEMA EAKQTLIEIR DFDGDTIEDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATCAGCAAA CTGTACAGTG CCAGTTGTGT AGATTTTGAA AAATGTCTGA AGTTTAGTGG 60
TTGCATCTAC CTCCTACCTG GTCTCCATCT TTTAAGAAAG AATAAATGTG ATGTCCGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030605--KLHL8
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005654--C:nucleoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

ocu:100352690

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001443	Ailuropoda melanoleuca	97.09	0.00e+00	1214.00
IUUC-Atr-002726	Amborella trichopoda	35.93	8.00e-42	165.00
IUUC-Apl-003978	Anas platyrhynchos	89.52	0.00e+00	1151.00
IUUC-Aca-004958	Anolis carolinensis	85.81	0.00e+00	1071.00
IUUC-Aor-010180	Aspergillus oryzae	25.38	1.00e-08	53.90
IUUC-Ame-011139	Astyanax mexicanus	84.60	0.00e+00	1066.00
IUUC-Bta-013142	Bos taurus	96.28	0.00e+00	1206.00
IUUC-Cel-018551	Caenorhabditis elegans	41.42	8.00e-131	461.00
IUUC-Cja-019650	Callithrix jacchus	95.48	0.00e+00	1224.00
IUUC-Cfa-021046	Canis familiaris	97.09	0.00e+00	1213.00
IUUC-Cpo-022445	Cavia porcellus	94.18	0.00e+00	1154.00
IUUC-Csa-023642	Chlorocebus sabaeus	96.45	0.00e+00	1233.00
IUUC-Cho-025012	Choloepus hoffmanni	79.38	0.00e+00	889.00
IUUC-Dre-027723	Danio rerio	82.40	0.00e+00	1052.00
IUUC-Dno-028964	Dasypus novemcinctus	94.73	0.00e+00	1000.00
IUUC-Dor-030899	Dipodomys ordii	83.11	8.00e-136	477.00
IUUC-Ete-032815	Echinops telfairi	92.57	0.00e+00	1186.00
IUUC-Eca-034162	Equus caballus	97.42	0.00e+00	1209.00
IUUC-Eeu-034660	Erinaceus europaeus	94.18	0.00e+00	1185.00
IUUC-Fca-035659	Felis catus	97.42	0.00e+00	1217.00
IUUC-Fal-037619	Ficedula albicollis	90.15	0.00e+00	1150.00
IUUC-Fox-037999	Fusarium oxysporum	31.17	3.00e-08	51.60
IUUC-Gmo-038546	Gadus morhua	84.25	0.00e+00	1046.00
IUUC-Gga-040770	Gallus gallus	89.03	0.00e+00	1127.00
IUUC-Gac-042557	Gasterosteus aculeatus	80.91	0.00e+00	1031.00
IUUC-Ggo-044741	Gorilla gorilla	96.13	0.00e+00	1230.00
IUUC-Hsa-046025	Homo sapiens	95.97	0.00e+00	1228.00
IUUC-Itr-048541	Ictidomys tridecemlineatus	97.45	0.00e+00	1100.00
IUUC-Loc-052834	Lepisosteus oculatus	86.16	0.00e+00	1002.00
IUUC-Laf-054513	Loxodonta africana	96.28	0.00e+00	1203.00
IUUC-Mcc-054707	Macaca mulatta	96.29	0.00e+00	1229.00
IUUC-Meu-056779	Macropus eugenii	93.78	0.00e+00	1149.00
IUUC-Mtr-058180	Medicago truncatula	32.95	1.00e-35	144.00
IUUC-Mga-059676	Meleagris gallopavo	88.87	0.00e+00	1126.00
IUUC-Mmr-061359	Microcebus murinus	95.00	0.00e+00	1182.00
IUUC-Mdo-062527	Monodelphis domestica	91.86	0.00e+00	1144.00
IUUC-Mmu-063112	Mus musculus	92.53	0.00e+00	1199.00
IUUC-Mac-064682	Musa acuminata	35.93	1.00e-41	164.00
IUUC-Mpu-065800	Mustela putorius furo	96.61	0.00e+00	1211.00
IUUC-Mlu-067536	Myotis lucifugus	95.11	0.00e+00	1150.00
IUUC-Nle-069397	Nomascus leucogenys	96.29	0.00e+00	1232.00
IUUC-Opr-070599	Ochotona princeps	96.48	0.00e+00	1016.00
IUUC-Ont-072580	Oreochromis niloticus	82.26	0.00e+00	1044.00
IUUC-Oan-073180	Ornithorhynchus anatinus	91.11	0.00e+00	1165.00
IUUC-Obr-076181	Oryza brachyantha	32.03	9.00e-36	145.00
IUUC-Ola-086776	Oryzias latipes	81.59	0.00e+00	1001.00
IUUC-Oga-088651	Otolemur garnettii	96.62	0.00e+00	1206.00
IUUC-Oar-089567	Ovis aries	95.15	0.00e+00	1182.00
IUUC-Ptr-091564	Pan troglodytes	96.13	0.00e+00	1230.00
IUUC-Pan-092578	Papio anubis	96.45	0.00e+00	1233.00
IUUC-Psi-093635	Pelodiscus sinensis	88.76	0.00e+00	1080.00
IUUC-Pma-094660	Petromyzon marinus	62.16	0.00e+00	761.00
IUUC-Pfo-097507	Poecilia formosa	81.74	0.00e+00	970.00
IUUC-Pab-098025	Pongo abelii	96.13	0.00e+00	1230.00
IUUC-Pca-101046	Procavia capensis	86.85	0.00e+00	629.00
IUUC-Ppe-101154	Prunus persica	33.07	6.00e-39	155.00
IUUC-Pva-102359	Pteropus vampyrus	97.27	0.00e+00	900.00
IUUC-Rno-105750	Rattus norvegicus	93.08	0.00e+00	1183.00
IUUC-Sha-107513	Sarcophilus harrisii	92.10	0.00e+00	1176.00
IUUC-Sly-111482	Solanum lycopersicum	32.68	4.00e-42	166.00
IUUC-Stu-112032	Solanum tuberosum	33.85	2.00e-43	170.00
IUUC-Sar-113616	Sorex araneus	71.33	4.00e-119	421.00
IUUC-Ssc-116205	Sus scrofa	96.09	0.00e+00	1012.00
IUUC-Tgu-117435	Taeniopygia guttata	90.31	0.00e+00	1150.00
IUUC-Tru-118709	Takifugu rubripes	81.59	0.00e+00	1040.00
IUUC-Tsy-119466	Tarsius syrichta	98.36	0.00e+00	1103.00
IUUC-Tni-119988	Tetraodon nigroviridis	81.45	0.00e+00	1035.00
IUUC-Tae-124761	Triticum aestivum	33.92	8.00e-38	152.00
IUUC-Tur-126089	Triticum urartu	27.94	5.00e-38	153.00
IUUC-Tbe-127704	Tupaia belangeri	95.80	0.00e+00	1056.00
IUUC-Ttr-128892	Tursiops truncatus	98.06	0.00e+00	924.00
IUUC-Vpa-130545	Vicugna pacos	97.06	0.00e+00	1017.00
IUUC-Xtr-132289	Xenopus tropicalis	82.79	0.00e+00	1011.00
IUUC-Xma-133419	Xiphophorus maculatus	83.27	0.00e+00	944.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence