iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mac-065645

Ensembl Protein ID

GSMUA_Achr7P09840_001

UniProt Accession

M0TG72; M0TG72_MUSAM

Protein Name

Coatomer subunit beta'

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GSMUA_Achr7G09840_001	GSMUA_Achr7T09840_001	GSMUA_Achr7P09840_001

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.80e-33	112.6	136	176
UBD/Beta-Prp	1.00e-58	199.7	3	240

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+ +v+c+++    d ++l++GsdD t kvWD+ t  ++++
   Q: 136  HSKGVNCVDYftgGDrPYLITGSDDQTAKVWDYQTKSCIQT 176
           999*****966*9778******************9999885 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetl 133
           +s++  e +v++ kf+ ++++ v g++D++i+v++++t + v ++++h+d++++++++p+  +++s s+d  i++wd+e+g+   +++
   Q: 3    KSFEVTELPVRSAKFIARKQWVVAGADDMFIRVYNYNTMDKVKVFEAHTDYIRCVAVHPTLPYVLSSSDDMLIKLWDWEKGWICTQIF 90
           678888999*************************************************************************9999** PP
   S: 134  sghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvysls..fdsngkelvsgsldgtvklwdlqtgecvrtl 218
           +gh++ v+ v+++p++ n ++s+slDrtv++W+l++ +   tl   h + v++++     ++++l++gs+d+t k+wd+qt++c++tl
   Q: 91   EGHSHYVMQVTFNPKDtNTFASASLDRTVKIWNLASPDPNFTLDA-HSKGVNCVDyfTGGDRPYLITGSDDQTAKVWDYQTKSCIQTL 177
           *******************************************98.*********7445566************************** PP
   S: 219  nghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlv 281
           +ght nv+ v f+p+  ++++gs+Dg++riW  ++  l ++l++  ++v++v +++ +++v++
   Q: 178  EGHTHNVSAVCFHPELPIIITGSEDGTVRIWHATTYRLENALNYGLERVWAVGYMKRSRRVVI 240
           ****************************************************99776666664 PP

Organism

Musa acuminata

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MVKSFEVTEL PVRSAKFIAR KQWVVAGADD MFIRVYNYNT MDKVKVFEAH TDYIRCVAVH 60
PTLPYVLSSS DDMLIKLWDW EKGWICTQIF EGHSHYVMQV TFNPKDTNTF ASASLDRTVK 120

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Nucleotide Sequence
(Fasta)

ATGGTAAAAT CTTTTGAGGT CACTGAATTA CCAGGTACAC TACACTGTAT CCTAGCCTTT 60
TCTGATGTTA CTAGAGTTTG TTATATATTC TGAACATTTA TTTATTGGGA TTTCAGTCCG 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence