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Tag Content
UUCD2 ID IUUC-Pab-098652
UUCD1 version UUC-PoA-00126
Ensembl Protein ID ENSPPYP00000003683.2
UniProt Accession H2ND86; H2ND86_PONAB
Genbank Protein ID ENSPPYP00000003683
Protein Name DNA damage-binding protein 1
Genbank Nucleotide ID ABGA01076013
Gene Name DDB1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPPYG00000003193.2 ENSPPYT00000003815.2 ENSPPYP00000003683.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DDB1 0 1650.1 1 1135
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DDB1
   S: 2    mldrYvvtarkpsavvklvvgnftshkelNLliaksnrieiflvtpeglrpvvevklegsiavlrlfrpknekkdllfilteryntl 88
           m+++Yvvta+kp+av+ +v+g+fts+++lNLliak++r+ei++vt+eglrpv+ev ++g+iav++lfrpk+e+kdllfilt++yn++
   Q: 1    MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNAC 87
           799************************************************************************************ PP
   S: 89   ilelrdidessevvtradgevlDdigrssdsGlinviepkirlialelyqglfklIvldndikelkafnirleelnvsdvkflillt 175
           ile+++++es++++tra+g+v+D+igr+s++G+i++i+p++r+i+l+ly+glfk+I+ld+d+kelkafnirleel+v+dvkfl++++
   Q: 88   ILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQ 174
           *************************************************************************************** PP
   S: 176  qptgrvlviyqdddgkhlktyelslkdKeFvkis.kqesiekeaellipvpsqlvgvlvlgeesivyksadnykdvdPylirqstai 261
           +pt  ++++yqd++g+h+ktye+sl++KeF+k++ kqe++e+ea+++i+vp++++g++++g+esi+y+++d+y +++P++i+qst++
   Q: 175  APT--ICFVYQDPQGRHVKTYEVSLREKEFNKGPwKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIV 259
           ***..********************************************************************************** PP
   S: 262  ryervdnngirylLgdfdGelkllllsaeeemsG.vevkslkielLgeisiaesisyldngllfvgsrfgdsQlvklisestgkgsy 347
           +++rvd ng+rylLgd++G+l++lll++ee+m+G v++k+l++elLge+siae+++yldng++fvgsr+gdsQlvkl+++s+++gsy
   Q: 260  CHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGtVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSY 346
           *************************************************************************************** PP
   S: 348  vvilerfknlkpIvdlvvvdldrrgqgqvvtvsgaskdGslRvirlgigieelasvdlkgvigllslkstidestdnslvlafvset 434
           vv++e+f+nl+pIvd++vvdl+r+gqgq+vt+sga+k+GslR+ir+gigi+e+as+dl+g++gl+  +s+ +++td++ vl+fv++t
   Q: 347  VVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWC-RSDPNRETDDT-VLSFVGQT 431
           *****************************************************************5.9*******986.89****** PP
   S: 435  kvlnlntgeeledtelsgvlsdlqtlltqdvidykqllqvTsqsvrLvssqikrllkeWkaknleiigvassNteqvliaatsndlv 521
               ln gee+e+tel+g+++d+qt+++ +v +++  +q+Ts+svrLvs++ k+l++eW+++ +++i+vas+N++qv++a+ +++l+
   Q: 432  SSQCLN-GEEVEETELMGFVDDQQTFFCGNV-AHQ-QIQITSASVRLVSQEPKALVSEWEPQ-AKNISVASCNSSQVVVAV-GRALY 513
           ******.************************.555.59*********************975.6789*************9.***** PP
   S: 522  yleigdgeldltstttlenevavldlinieddpnlsdleavglltdiskrililpdl.etiykeklggeiipRsilltefEnvtYlL 607
           yl+i+++el+++s+t++e+eva+ld+++++d ++ + l+a+gl  +is+ril+   + +  ++e+lgg iipRsil+t+fE+ +YlL
   Q: 514  YLQIHPQELRQISHTEMEHEVACLDITPLGD-RQCTPLCAIGL-RTISARILKVALFwNYCTREMLGGRIIPRSILMTTFESSHYLL 598
           *******************************.77788999997.67******998763677899*********************** PP
   S: 608  ialgdGalvsyildidtgdesdakksnlgtspgtlktfkslsttqvfassDrPtvIyssskkLvfSnVnlkeVqylCsldseaypd. 693
           +algdGal+++ l+i+tg +sd+kk++lgt+p++l+ f+slstt+vfa+sDrPtvIyss+ kLvfSnVnlkeV+y+C+l+  ayp+ 
   Q: 599  CALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLR-FRSLSTTNVFACSDRPTVIYSSN-KLVFSNVNLKEVNYMCPLKF-AYPEq 682
           **********************************98.8*******************976.8*****************97.67762 PP
   S: 694  slalanngslvigtvddiqklkiRsiplgeslrriayqesvitfgvisdrreldf.klklkalrnnasilalvpdiennklfsdglr 779
           +     n++l+igt+d iqkl+iR++pl+es+r+i+yqe++++fgv+ +r+e+++ +++++alr++as++a  +    +klfs++++
   Q: 683  AWHWPTNSTLTIGTID-IQKLHIRTVPLYESPRKICYQEVSQCFGVS-SRIEVQDtSGGTTALRPSASTQAKGTVSAPSKLFSSSTA 767
           5778999********6.****************************96.68999999******************************* PP
   S: 780  ilelseleenevnfllvlDkntfelllaqdlrewEtavsllSqklkdDseeyyvvktalvlpeenelkkgrilvfsvedslklkLlt 866
            +e+s++ee+ev++ll++D++tfe+l+a+++ ++E+a+sl+S+kl++D+++y++v+ta+v+pee+e+k+gri+vf+++d+   kL+t
   Q: 768  PHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDG---KLQT 851
           ********************************************************************************...**** PP
   S: 867  vaekkvkgavidlvklNgkllaainseirlyewkvmgtdekelrkeCernntilaLtlktrkdfivVgDlmrsvtLllykdlegsfe 953
           vaek+vkgav+++v++Ngklla+ins++rlyew    t+ekelr+eC+++n+i+aL+lkt++dfi+VgDlmrsv Ll+yk +eg+fe
   Q: 852  VAEKEVKGAVYSMVEFNGKLLASINSTVRLYEW----TTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFE 934
           *********************************....************************************************** PP
   S: 954  EsardynlewmsaveilnddiflgaencgNlfvvkkdikagltdeerslleevgefrlgefvevfrfgtlvlqdvgerevnrssevi 1040
           E+ard+n++wmsaveil+dd+flgaen++Nlfv++kd +a++tdeer++l+evg f+lgefv+vf++g+lv+q++ge++++++++v+
   Q: 935  EIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKD-SAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVL 1020
           *************************************.************************************************* PP
   S: 1041 fgtengeigvilrlrrellkflrnlestlkkvikrvaki...eH.ssyRsFetekrterasgfvdgdLiesilDlsrdkavdilkvl 1123
           fgt+ng+ig++++l+++++++l +++++l+kvik+v+      H s +RsF+te++te+a+gf+dgdLies+lD+sr+k+++++++l
   Q: 1021 FGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGLTcslTHpSTWRSFHTER
Organism Pongo abelii
Protein Sequence
(Fasta)
MSYNYVVTAQ KPTAVNGCVT GHFTSAEDLN LLIAKNTRLE IYVVTAEGLR PVKEVGMYGK 60
IAVMELFRPK GESKDLLFIL TAKYNACILE YKQSGESIDI ITRAHGNVQD RIGRPSETGI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Pab-098652|E3,DDB1|Pongo abelii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCCTCCGCAG TCCTTTCCGT TCCTAAAGGA GGAACAGCCC GAGGGCTCCT GGAGCAACGG 60
AAGGAGGAGG ACTGGATGCG GGGAAGGGCA AAGGGCGCGG AACGGGGTGG GGAGTCTGCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Pab-098652|E3,DDB1|Pongo abelii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR004871--Cleavage/polyA-sp_fac_asu_C
IPR031297--DDB1
IPR015943--WD40/YVTN_repeat-like_dom
IPR017986--WD40_repeat_dom
Pfam

PF03178--CPSF_A
Gene Ontology

GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex
GO:0031465--C:Cul4B-RING E3 ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005615--C:extracellular space
GO:0000784--C:nuclear chromosome, telomeric region
GO:0005654--C:nucleoplasm
GO:0003684--F:damaged DNA binding
GO:0035518--P:histone H2A monoubiquitination
GO:0051702--P:interaction with symbiont
GO:0043066--P:negative regulation of apoptotic process
GO:0046726--P:positive regulation by virus of viral protein levels in host cell
GO:0045070--P:positive regulation of viral genome replication
GO:1902188--P:positive regulation of viral release from host cell
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:1901990--P:regulation of mitotic cell cycle phase transition
GO:0070914--P:UV-damage excision repair
GO:0016055--P:Wnt signaling pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000120 Aegilops tauschii 48.29 0.00e+00 1032.00
IUUC-Aml-002096 Ailuropoda melanoleuca 94.94 0.00e+00 2143.00
IUUC-Atr-002742 Amborella trichopoda 50.17 0.00e+00 1076.00
IUUC-Apl-003624 Anas platyrhynchos 91.86 0.00e+00 2030.00
IUUC-Aca-005085 Anolis carolinensis 92.32 0.00e+00 2081.00
IUUC-Aly-005857 Arabidopsis lyrata 51.04 0.00e+00 1084.00
IUUC-Ath-006658 Arabidopsis thaliana 50.87 0.00e+00 1081.00
IUUC-Acl-008149 Aspergillus clavatus 26.52 5.00e-86 312.00
IUUC-Afl-008549 Aspergillus flavus 27.67 1.00e-89 325.00
IUUC-Afu-009076 Aspergillus fumigatus 26.76 7.00e-96 345.00
IUUC-Ani-009302 Aspergillus nidulans 26.13 1.00e-72 268.00
IUUC-Ang-009636 Aspergillus niger 26.86 3.00e-63 237.00
IUUC-Aor-010073 Aspergillus oryzae 27.75 3.00e-94 340.00
IUUC-Ate-010422 Aspergillus terreus 26.52 4.00e-85 310.00
IUUC-Ame-011643 Astyanax mexicanus 78.18 0.00e+00 1730.00
IUUC-Bgr-012164 Blumeria graminis 25.24 1.00e-76 281.00
IUUC-Bta-012494 Bos taurus 94.85 0.00e+00 2141.00
IUUC-Bci-013957 Botrytis cinerea 25.85 4.00e-76 280.00
IUUC-Bdi-014186 Brachypodium distachyon 50.87 0.00e+00 1076.00
IUUC-Bol-015922 Brassica oleracea 51.30 0.00e+00 1094.00
IUUC-Bra-017300 Brassica rapa 51.35 0.00e+00 1094.00
IUUC-Cel-018239 Caenorhabditis elegans 36.51 0.00e+00 712.00
IUUC-Cja-019165 Callithrix jacchus 95.03 0.00e+00 2144.00
IUUC-Cfa-020406 Canis familiaris 94.94 0.00e+00 2143.00
IUUC-Cpo-022154 Cavia porcellus 94.24 0.00e+00 2126.00
IUUC-Cre-022557 Chlamydomonas reinhardtii 39.41 0.00e+00 698.00
IUUC-Csa-024061 Chlorocebus sabaeus 95.03 0.00e+00 2144.00
IUUC-Cho-024554 Choloepus hoffmanni 87.05 0.00e+00 864.00
IUUC-Cin-025466 Ciona intestinalis 59.59 0.00e+00 1357.00
IUUC-Csv-026370 Ciona savignyi 57.89 0.00e+00 1209.00
IUUC-Cgl-026595 Colletotrichum gloeosporioides 24.98 4.00e-78 286.00
IUUC-Cme-027342 Cyanidioschyzon merolae 26.79 1.00e-94 342.00
IUUC-Dre-027448 Danio rerio 86.43 0.00e+00 952.00
IUUC-Dno-029794 Dasypus novemcinctus 94.18 0.00e+00 2004.00
IUUC-Dor-030789 Dipodomys ordii 84.65 0.00e+00 737.00
IUUC-Dse-031491 Dothistroma septosporum 26.76 2.00e-92 333.00
IUUC-Dme-031940 Drosophila melanogaster 58.30 0.00e+00 1262.00
IUUC-Ete-032913 Echinops telfairi 76.25 0.00e+00 797.00
IUUC-Eca-033777 Equus caballus 94.33 0.00e+00 2125.00
IUUC-Eeu-034900 Erinaceus europaeus 91.76 0.00e+00 1031.00
IUUC-Fca-035869 Felis catus 94.94 0.00e+00 2143.00
IUUC-Fal-036777 Ficedula albicollis 92.41 0.00e+00 2079.00
IUUC-Fox-037954 Fusarium oxysporum 25.53 2.00e-84 307.00
IUUC-Fso-038292 Fusarium solani 25.00 3.00e-88 320.00
IUUC-Gmo-038815 Gadus morhua 76.76 0.00e+00 859.00
IUUC-Ggr-039907 Gaeumannomyces graminis 24.25 2.00e-77 284.00
IUUC-Gga-040995 Gallus gallus 92.41 0.00e+00 2083.00
IUUC-Gac-042390 Gasterosteus aculeatus 86.14 0.00e+00 1848.00
IUUC-Gma-042904 Glycine max 49.43 0.00e+00 1036.00
IUUC-Ggo-044891 Gorilla gorilla 95.20 0.00e+00 2154.00
IUUC-Hsa-046709 Homo sapiens 95.03 0.00e+00 2144.00
IUUC-Hvu-047504 Hordeum vulgare 50.43 0.00e+00 1058.00
IUUC-Itr-048678 Ictidomys tridecemlineatus 94.85 0.00e+00 2142.00
IUUC-Lch-050565 Latimeria chalumnae 89.28 0.00e+00 2024.00
IUUC-Lpe-051260 Leersia perrieri 50.91 0.00e+00 1074.00
IUUC-Loc-052091 Lepisosteus oculatus 78.45 0.00e+00 1365.00
IUUC-Lma-053246 Leptosphaeria maculans 24.59 7.00e-81 295.00
IUUC-Laf-053502 Loxodonta africana 94.68 0.00e+00 2139.00
IUUC-Mcc-054802 Macaca mulatta 94.99 0.00e+00 2126.00
IUUC-Meu-056808 Macropus eugenii 90.48 0.00e+00 1301.00
IUUC-Mor-057253 Magnaporthe oryzae 25.18 2.00e-68 254.00
IUUC-Mpo-057562 Magnaporthe poae 24.41 1.00e-76 281.00
IUUC-Mtr-057743 Medicago truncatula 49.70 0.00e+00 1056.00
IUUC-Mla-059154 Melampsora laricipopulina 24.86 5.00e-72 266.00
IUUC-Mga-059824 Meleagris gallopavo 91.66 0.00e+00 1939.00
IUUC-Mvi-060279 Microbotryum violaceum 26.38 7.00e-95 342.00
IUUC-Mmr-061215 Microcebus murinus 94.33 0.00e+00 2126.00
IUUC-Mdo-062028 Monodelphis domestica 91.98 0.00e+00 1737.00
IUUC-Mmu-064327 Mus musculus 94.68 0.00e+00 2137.00
IUUC-Mac-065445 Musa acuminata 50.56 0.00e+00 1046.00
IUUC-Mpu-065814 Mustela putorius furo 92.23 0.00e+00 2058.00
IUUC-Mlu-067136 Myotis lucifugus 94.33 0.00e+00 2124.00
IUUC-Nfi-068355 Neosartorya fischeri 26.84 2.00e-90 327.00
IUUC-Ncr-068620 Neurospora crassa 24.56 9.00e-73 268.00
IUUC-Nle-069566 Nomascus leucogenys 94.81 0.00e+00 2113.00
IUUC-Opr-070915 Ochotona princeps 85.63 0.00e+00 1704.00
IUUC-Ont-071753 Oreochromis niloticus 87.09 0.00e+00 1964.00
IUUC-Oan-073187 Ornithorhynchus anatinus 92.77 0.00e+00 1890.00
IUUC-Ocu-074619 Oryctolagus cuniculus 95.03 0.00e+00 2146.00
IUUC-Oba-075091 Oryza barthii 43.00 0.00e+00 764.00
IUUC-Obr-076425 Oryza brachyantha 51.66 0.00e+00 1076.00
IUUC-Ogu-078794 Oryza glumaepatula 51.17 0.00e+00 1079.00
IUUC-Oin-079725 Oryza indica 51.26 0.00e+00 1069.00
IUUC-Olo-080842 Oryza longistaminata 49.63 0.00e+00 979.00
IUUC-Ome-081818 Oryza meridionalis 51.26 0.00e+00 1083.00
IUUC-Oni-082879 Oryza nivara 50.48 0.00e+00 1055.00
IUUC-Opu-083361 Oryza punctata 50.34 0.00e+00 1071.00
IUUC-Oru-084781 Oryza rufipogon 51.17 0.00e+00 1081.00
IUUC-Osa-086293 Oryza sativa 51.17 0.00e+00 1081.00
IUUC-Ola-086881 Oryzias latipes 85.99 0.00e+00 1946.00
IUUC-Olu-087674 Ostreococcus lucimarinus 44.30 0.00e+00 883.00
IUUC-Oga-089056 Otolemur garnettii 94.76 0.00e+00 2138.00
IUUC-Oar-089457 Ovis aries 94.77 0.00e+00 2104.00
IUUC-Ptr-091179 Pan troglodytes 94.77 0.00e+00 2102.00
IUUC-Pan-092019 Papio anubis 95.03 0.00e+00 2149.00
IUUC-Psi-093407 Pelodiscus sinensis 92.12 0.00e+00 2041.00
IUUC-Pma-094272 Petromyzon marinus 82.75 0.00e+00 1708.00
IUUC-Pno-094864 Phaeosphaeria nodorum 26.39 7.00e-92 332.00
IUUC-Ppa-095885 Physcomitrella patens 51.21 0.00e+00 1065.00
IUUC-Pfo-096083 Poecilia formosa 86.74 0.00e+00 1961.00
IUUC-Pop-099593 Populus trichocarpa 50.91 0.00e+00 1034.00
IUUC-Pca-100189 Procavia capensis 92.31 0.00e+00 1194.00
IUUC-Ppe-101987 Prunus persica 50.48 0.00e+00 1020.00
IUUC-Pva-102605 Pteropus vampyrus 94.76 0.00e+00 2138.00
IUUC-Pgr-103659 Puccinia graminis 24.19 4.00e-61 230.00
IUUC-Ptt-103884 Puccinia triticina 22.58 5.00e-44 173.00
IUUC-Pte-104233 Pyrenophora teres 26.16 3.00e-94 340.00
IUUC-Pyt-104454 Pyrenophora triticirepentis 26.72 2.00e-92 334.00
IUUC-Rno-106004 Rattus norvegicus 94.76 0.00e+00 2139.00
IUUC-Sha-106726 Sarcophilus harrisii 91.73 0.00e+00 1920.00
IUUC-Sja-107864 Schizosaccharomyces japonicus 24.12 6.00e-65 242.00
IUUC-Spo-108029 Schizosaccharomyces pombe 25.38 5.00e-89 322.00
IUUC-Ssl-108441 Sclerotinia sclerotiorum 24.90 3.00e-67 250.00
IUUC-Smo-108862 Selaginella moellendorffii 50.61 0.00e+00 1108.00
IUUC-Sit-109735 Setaria italica 51.66 0.00e+00 1068.00
IUUC-Sly-111520 Solanum lycopersicum 50.04 0.00e+00 1051.00
IUUC-Sar-113606 Sorex araneus 86.36 6.00e-111 395.00
IUUC-Sbi-114539 Sorghum bicolor 50.70 0.00e+00 1056.00
IUUC-Sre-114936 Sporisorium reilianum 24.35 4.00e-54 207.00
IUUC-Ssc-116038 Sus scrofa 94.76 0.00e+00 2137.00
IUUC-Tgu-117512 Taeniopygia guttata 92.76 0.00e+00 2088.00
IUUC-Tru-117593 Takifugu rubripes 85.79 0.00e+00 1939.00
IUUC-Tsy-119513 Tarsius syrichta 90.06 0.00e+00 1080.00
IUUC-Tni-120551 Tetraodon nigroviridis 80.46 0.00e+00 1556.00
IUUC-Tca-121505 Theobroma cacao 51.17 0.00e+00 1054.00
IUUC-Tre-122136 Trichoderma reesei 25.10 6.00e-83 302.00
IUUC-Tvi-122512 Trichoderma virens 24.21 1.00e-79 291.00
IUUC-Tae-124186 Triticum aestivum 50.35 0.00e+00 1058.00
IUUC-Tur-126451 Triticum urartu 50.67 0.00e+00 954.00
IUUC-Tme-127057 Tuber melanosporum 28.16 4.00e-97 349.00
IUUC-Ttr-128891 Tursiops truncatus 88.60 0.00e+00 1321.00
IUUC-Uma-129583 Ustilago maydis 25.61 8.00e-45 176.00
IUUC-Vda-129870 Verticillium dahliae 24.05 3.00e-73 270.00
IUUC-Vpa-130117 Vicugna pacos 90.15 0.00e+00 1612.00
IUUC-Vvi-131033 Vitis vinifera 50.13 0.00e+00 1053.00
IUUC-Xtr-131987 Xenopus tropicalis 88.87 0.00e+00 1993.00
IUUC-Xma-134117 Xiphophorus maculatus 84.77 0.00e+00 1911.00
IUUC-Zma-134758 Zea mays 51.26 0.00e+00 1072.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
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