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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Ath-007596
UUCD1 version UUC-ArT-01605
Ensembl Protein ID AT2G36060.2
UniProt Accession Q9SJ44; A8MQX2; Q3EBM3; UEV1C_ARATH
Genbank Protein ID AAD21451.1; AEC09199.1; AEC09200.1; AEC09201.1; AAL32838.1; AAM13381.1
Protein Name Ubiquitin-conjugating enzyme E2 variant 1C; Protein MMS ZWEI HOMOLOG 3
Genbank Nucleotide ID AC007017; CP002685; CP002685; CP002685; AY062760; AY093382
Gene Name UEV1C; MMZ3; At2g36060; F11F19.3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT2G36060 AT2G36060.3 AT2G36060.3
AT2G36060 AT2G36060.1 AT2G36060.1
AT2G36060 AT2G36060.2 AT2G36060.2
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
Mentha
Post-translational Modifications (PTMs)
dbPPTdbPTM
Protein Expression/Proteomics
GPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
E2/UEV E2_UEV 18178771
Classification
Family E-value Score Start End
E2/UEV 3.00e-68 229.1 5 146
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E2/UEV
   S: 5    selkvvvprnfrlleeleegekglgdgtvsygldDgddilllsltgtIigper.tayegrIyqlklfvgkkYPekPPtvrfsskinmaevndsnGvvd 101
           s+++vvvprnfrlleele+gekg+gdgtvsyg+dDgddi+++s+tgtIigp++ t++egrIyqlklf++k+YPekPPtvrf+s+inm++vn+++Gvvd
   Q: 5    SGSSVVVPRNFRLLEELERGEKGIGDGTVSYGMDDGDDIYMRSWTGTIIGPHNvTVHEGRIYQLKLFCDKDYPEKPPTVRFHSRINMTCVNHDTGVVD 102
           5789************************************************9789****************************************** PP
   S: 102  pralpvLanWkreysievvlvqlkkellskenrklqqPpeGnlf 145
           +++++vLanW+r+y++e++l+qlkke+++++nrkl+qPpeG++f
   Q: 103  SKKFGVLANWQRQYTMEDILTQLKKEMAASHNRKLVQPPEGTFF 146
           *****************************************986 PP
   
Organism Arabidopsis thaliana
Functional Description
(View)

Functional Description


     Has no ubiquitin ligase activity on its own. The heterodimer with UBC catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. May play a role in the control of progress through the cell cycle and differentiation. May play a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
 Has no ubiquitin ligase activity on its own. The heterodimer with UBC catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. May play a role in the control of progress through the cell cycle and differentiation. May play a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
Protein Sequence
(Fasta)
MTLGSGSSVV VPRNFRLLEE LERGEKGIGD GTVSYGMDDG DDIYMRSWTG TIIGPHNVTV 60
HEGRIYQLKL FCDKDYPEKP PTVRFHSRIN MTCVNHDTGV VDSKKFGVLA NWQRQYTMED 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ath-007596|E2,E2/UEV|Arabidopsis thaliana
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Nucleotide Sequence
(Fasta)
AGCCCACTCC AATTCTCGTC GCACCAATAG AGTAATTCAA CTGCCCCAAA TTGCTCTCGA 60
CTTTTTATTC TCGGATTAGC GTTTGTGCTT TCGCATCAGA GAATCTCTCA GTTCTTCTCA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ath-007596|E2,E2/UEV|Arabidopsis thaliana
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD
PROSITE

PS50127--UBIQUITIN_CONJUGAT_2
Pfam

PF00179--UQ_con
Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006301--P:postreplication repair
GO:0070534--P:protein K63-linked ubiquitination
KEGG ath:AT2G36060
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000910 Aegilops tauschii 85.62 2.00e-68 249.00
IUUC-Atr-003005 Amborella trichopoda 90.48 4.00e-73 265.00
IUUC-Acl-008375 Aspergillus clavatus 53.52 8.00e-35 138.00
IUUC-Afl-008598 Aspergillus flavus 52.52 7.00e-34 135.00
IUUC-Afu-008838 Aspergillus fumigatus 54.41 2.00e-35 140.00
IUUC-Ang-009631 Aspergillus niger 54.41 1.00e-34 137.00
IUUC-Aor-010051 Aspergillus oryzae 52.52 7.00e-34 135.00
IUUC-Ate-010471 Aspergillus terreus 51.08 1.00e-29 120.00
IUUC-Ame-010710 Astyanax mexicanus 48.63 7.00e-40 155.00
IUUC-Bta-013403 Bos taurus 52.74 2.00e-39 153.00
IUUC-Bci-013649 Botrytis cinerea 55.88 7.00e-34 135.00
IUUC-Bdi-014636 Brachypodium distachyon 88.89 8.00e-67 244.00
IUUC-Cja-019316 Callithrix jacchus 52.74 2.00e-39 153.00
IUUC-Cre-022629 Chlamydomonas reinhardtii 61.87 1.00e-49 187.00
IUUC-Cho-025024 Choloepus hoffmanni 45.45 5.00e-22 94.70
IUUC-Cin-025219 Ciona intestinalis 41.90 7.00e-20 88.60
IUUC-Dre-028062 Danio rerio 50.00 3.00e-41 159.00
IUUC-Dse-031272 Dothistroma septosporum 55.15 3.00e-35 139.00
IUUC-Fal-037369 Ficedula albicollis 52.82 9.00e-38 148.00
IUUC-Gmo-039237 Gadus morhua 49.32 8.00e-40 155.00
IUUC-Gga-040634 Gallus gallus 52.82 9.00e-38 148.00
IUUC-Gma-043818 Glycine max 93.20 7.00e-75 271.00
IUUC-Hsa-045659 Homo sapiens 52.74 2.00e-39 153.00
IUUC-Hvu-047368 Hordeum vulgare 88.89 5.00e-67 245.00
IUUC-Kpa-049337 Komagataella pastoris 53.62 5.00e-34 135.00
IUUC-Lpe-050874 Leersia perrieri 90.37 7.00e-69 251.00
IUUC-Loc-052012 Lepisosteus oculatus 49.31 8.00e-41 158.00
IUUC-Laf-054176 Loxodonta africana 52.74 2.00e-39 153.00
IUUC-Mtr-058577 Medicago truncatula 91.28 3.00e-73 266.00
IUUC-Mvi-060260 Microbotryum violaceum 56.62 1.00e-37 147.00
IUUC-Mac-065394 Musa acuminata 87.07 1.00e-71 260.00
IUUC-Mpu-065775 Mustela putorius furo 52.74 2.00e-39 153.00
IUUC-Mlu-067269 Myotis lucifugus 50.00 1.00e-37 148.00
IUUC-Nle-069245 Nomascus leucogenys 52.74 2.00e-39 153.00
IUUC-Ont-072098 Oreochromis niloticus 50.69 5.00e-33 132.00
IUUC-Oan-073215 Ornithorhynchus anatinus 50.34 2.00e-35 140.00
IUUC-Oba-075005 Oryza barthii 90.37 3.00e-68 249.00
IUUC-Obr-076191 Oryza brachyantha 90.60 2.00e-73 266.00
IUUC-Ogl-077233 Oryza glaberrima 90.37 3.00e-68 249.00
IUUC-Ogu-078374 Oryza glumaepatula 90.37 3.00e-68 249.00
IUUC-Oin-079721 Oryza indica 90.37 3.00e-68 249.00
IUUC-Olo-080528 Oryza longistaminata 85.91 8.00e-68 248.00
IUUC-Ome-081761 Oryza meridionalis 90.37 5.00e-69 252.00
IUUC-Oni-082346 Oryza nivara 90.37 3.00e-68 249.00
IUUC-Opu-083148 Oryza punctata 90.37 3.00e-68 249.00
IUUC-Oru-084359 Oryza rufipogon 90.37 3.00e-68 249.00
IUUC-Osa-085664 Oryza sativa 90.37 3.00e-68 249.00
IUUC-Ola-087529 Oryzias latipes 51.03 2.00e-33 134.00
IUUC-Ptr-090866 Pan troglodytes 52.74 2.00e-39 153.00
IUUC-Psi-093138 Pelodiscus sinensis 52.82 9.00e-38 148.00
IUUC-Pma-094142 Petromyzon marinus 61.22 1.00e-14 69.70
IUUC-Pno-095070 Phaeosphaeria nodorum 55.88 2.00e-35 140.00
IUUC-Ppa-095557 Physcomitrella patens 78.87 2.00e-60 223.00
IUUC-Pfo-096657 Poecilia formosa 53.62 9.00e-33 132.00
IUUC-Ppe-101196 Prunus persica 91.84 2.00e-73 266.00
IUUC-Pgr-103617 Puccinia graminis 59.56 5.00e-36 142.00
IUUC-Rno-106065 Rattus norvegicus 52.05 2.00e-37 146.00
IUUC-Spo-108027 Schizosaccharomyces pombe 55.88 2.00e-34 137.00
IUUC-Ssl-108493 Sclerotinia sclerotiorum 55.88 6.00e-34 135.00
IUUC-Smo-109006 Selaginella moellendorffii 75.36 4.00e-53 199.00
IUUC-Sit-110196 Setaria italica 94.07 2.00e-70 256.00
IUUC-Sbi-114412 Sorghum bicolor 93.33 8.00e-70 254.00
IUUC-Ssc-115939 Sus scrofa 52.74 2.00e-39 153.00
IUUC-Tca-121288 Theobroma cacao 93.20 7.00e-75 271.00
IUUC-Tae-123220 Triticum aestivum 88.89 5.00e-67 245.00
IUUC-Tur-126236 Triticum urartu 87.68 7.00e-68 248.00
IUUC-Tme-127171 Tuber melanosporum 54.41 9.00e-32 128.00
IUUC-Vvi-131466 Vitis vinifera 92.52 3.00e-74 269.00
IUUC-Xma-133175 Xiphophorus maculatus 52.05 2.00e-34 136.00
IUUC-Zma-135558 Zea mays 91.85 4.00e-69 252.00
Created Date 25-Jun-2017

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