iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gga-040546

Ensembl Protein ID

ENSGALP00000017580.4

UniProt Accession

Q2LAI0; F1NLY6; Q2LAI0_CHICK

Genbank Protein ID

ABC67730.1

Protein Name

Non-specific serine/threonine protein kinase

Genbank Nucleotide ID

AADN04000032

Gene Name

PRKAA2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000010826.5	ENSGALT00000017601.5	ENSGALP00000017580.4

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	47.44	3.00e-125	446.00	IUUC-Ath-007014
UBD/Alpha-Helix/UBA	42.13	3.00e-107	383.00	IUUC-Spo-108202

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Gallus gallus

Protein Sequence
(Fasta)

MAEKQQKHDG RVKIGHYVLG DTLGVGTFGK VKVGEHQLTG HKVAVKILNR QKIRSLDVVG 60
KIKREIQNLK LFRHPHIIKL YQVISTPTDF FMVMEYVSGG ELFDYICKHG RVEEAEARRL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCCGGCCCT GCGCATTGTG GTCCTCCGCC GGGGGGCGAA GATGGCCGAG AAGCAGCAGA 60
AGCACGACGG GAGGGTGAAG ATCGGCCACT ACGTGCTGGG GGATACGCTG GGGGTCGGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR032270--AMPK_C
IPR028375--KA1/Ssp2_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF16579--AdenylateSensor
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005623--C:cell
GO:0005737--C:cytoplasm
GO:0005794--C:Golgi apparatus
GO:0016607--C:nuclear speck
GO:0031588--C:nucleotide-activated protein kinase complex
GO:0005634--C:nucleus
GO:0004679--F:AMP-activated protein kinase activity
GO:0005524--F:ATP binding
GO:0003682--F:chromatin binding
GO:0035174--F:histone serine kinase activity
GO:0004672--F:protein kinase activity
GO:0019901--F:protein kinase binding
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0035690--P:cellular response to drug
GO:0042149--P:cellular response to glucose starvation
GO:0071380--P:cellular response to prostaglandin E stimulus
GO:0034614--P:cellular response to reactive oxygen species
GO:0009267--P:cellular response to starvation
GO:0042593--P:glucose homeostasis
GO:0031649--P:heat generation
GO:0035404--P:histone-serine phosphorylation
GO:0035556--P:intracellular signal transduction
GO:0008610--P:lipid biosynthetic process
GO:0043066--P:negative regulation of apoptotic process
GO:0032007--P:negative regulation of TOR signaling
GO:0010508--P:positive regulation of autophagy
GO:0010628--P:positive regulation of gene expression
GO:0042752--P:regulation of circadian rhythm
GO:0016241--P:regulation of macroautophagy
GO:1904101--P:response to acadesine
GO:0042493--P:response to drug
GO:0014850--P:response to muscle activity

KEGG

gga:429110

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000713	Aegilops tauschii	46.02	3.00e-122	432.00
IUUC-Aml-001907	Ailuropoda melanoleuca	75.09	0.00e+00	789.00
IUUC-Atr-002770	Amborella trichopoda	48.27	2.00e-126	445.00
IUUC-Apl-003395	Anas platyrhynchos	99.42	0.00e+00	1078.00
IUUC-Aca-004480	Anolis carolinensis	93.92	0.00e+00	1033.00
IUUC-Aly-006289	Arabidopsis lyrata	47.34	1.00e-126	446.00
IUUC-Ath-007014	Arabidopsis thaliana	47.44	1.00e-126	446.00
IUUC-Ago-007957	Ashbya gossypii	43.39	6.00e-117	414.00
IUUC-Acl-008103	Aspergillus clavatus	60.07	4.00e-101	362.00
IUUC-Afl-008555	Aspergillus flavus	60.07	6.00e-102	365.00
IUUC-Afu-008949	Aspergillus fumigatus	60.07	3.00e-101	362.00
IUUC-Ani-009408	Aspergillus nidulans	60.73	2.00e-101	363.00
IUUC-Ang-009551	Aspergillus niger	60.07	5.00e-101	362.00
IUUC-Aor-010176	Aspergillus oryzae	60.07	7.00e-102	364.00
IUUC-Ate-010287	Aspergillus terreus	60.07	8.00e-101	361.00
IUUC-Ame-011019	Astyanax mexicanus	87.88	0.00e+00	1014.00
IUUC-Bgr-012045	Blumeria graminis	60.07	4.00e-102	365.00
IUUC-Bta-012786	Bos taurus	75.63	0.00e+00	789.00
IUUC-Bci-013774	Botrytis cinerea	60.14	7.00e-104	371.00
IUUC-Bdi-014319	Brachypodium distachyon	46.15	8.00e-124	437.00
IUUC-Bol-016242	Brassica oleracea	47.52	4.00e-129	454.00
IUUC-Bra-016750	Brassica rapa	47.73	2.00e-129	455.00
IUUC-Cel-018518	Caenorhabditis elegans	58.57	0.00e+00	633.00
IUUC-Cja-019386	Callithrix jacchus	92.04	0.00e+00	1052.00
IUUC-Cfa-020177	Canis familiaris	74.05	0.00e+00	761.00
IUUC-Cpo-021805	Cavia porcellus	91.86	0.00e+00	1050.00
IUUC-Cre-022915	Chlamydomonas reinhardtii	54.83	3.00e-96	344.00
IUUC-Csa-024267	Chlorocebus sabaeus	91.86	0.00e+00	1049.00
IUUC-Cho-024859	Choloepus hoffmanni	72.07	0.00e+00	748.00
IUUC-Cin-025550	Ciona intestinalis	60.00	0.00e+00	666.00
IUUC-Csv-026139	Ciona savignyi	59.41	0.00e+00	671.00
IUUC-Cne-027044	Cryptococcus neoformans	51.54	6.00e-109	388.00
IUUC-Cme-027289	Cyanidioschyzon merolae	44.97	3.00e-112	398.00
IUUC-Dre-027749	Danio rerio	70.59	0.00e+00	793.00
IUUC-Dno-030006	Dasypus novemcinctus	74.73	0.00e+00	788.00
IUUC-Dor-030578	Dipodomys ordii	91.68	0.00e+00	1051.00
IUUC-Dse-031507	Dothistroma septosporum	62.31	7.00e-104	371.00
IUUC-Dme-031704	Drosophila melanogaster	58.89	0.00e+00	658.00
IUUC-Ete-033055	Echinops telfairi	72.76	0.00e+00	806.00
IUUC-Eca-034016	Equus caballus	91.94	0.00e+00	997.00
IUUC-Fca-035754	Felis catus	73.37	0.00e+00	783.00
IUUC-Fal-037363	Ficedula albicollis	74.91	0.00e+00	783.00
IUUC-Fox-038073	Fusarium oxysporum	52.53	2.00e-104	373.00
IUUC-Fso-038236	Fusarium solani	52.39	2.00e-101	363.00
IUUC-Gmo-039633	Gadus morhua	70.63	0.00e+00	816.00
IUUC-Ggr-039987	Gaeumannomyces graminis	49.32	7.00e-102	364.00
IUUC-Gac-041822	Gasterosteus aculeatus	83.99	0.00e+00	951.00
IUUC-Gma-042712	Glycine max	47.14	3.00e-126	445.00
IUUC-Ggo-045303	Gorilla gorilla	92.04	0.00e+00	1055.00
IUUC-Hsa-045746	Homo sapiens	92.04	0.00e+00	1055.00
IUUC-Hvu-047406	Hordeum vulgare	45.96	3.00e-125	441.00
IUUC-Itr-048134	Ictidomys tridecemlineatus	91.86	0.00e+00	1053.00
IUUC-Kpa-049190	Komagataella pastoris	46.08	4.00e-122	431.00
IUUC-Lch-049623	Latimeria chalumnae	74.64	0.00e+00	782.00
IUUC-Lpe-051392	Leersia perrieri	46.22	4.00e-124	437.00
IUUC-Loc-052928	Lepisosteus oculatus	91.14	0.00e+00	1027.00
IUUC-Lma-053054	Leptosphaeria maculans	62.55	2.00e-105	376.00
IUUC-Laf-053459	Loxodonta africana	92.77	0.00e+00	1063.00
IUUC-Mcc-055862	Macaca mulatta	92.04	0.00e+00	1055.00
IUUC-Mor-057170	Magnaporthe oryzae	51.31	1.00e-100	360.00
IUUC-Mpo-057302	Magnaporthe poae	49.45	9.00e-102	364.00
IUUC-Mtr-058309	Medicago truncatula	47.17	3.00e-124	438.00
IUUC-Mla-059058	Melampsora laricipopulina	42.06	5.00e-103	368.00
IUUC-Mga-059206	Meleagris gallopavo	99.62	0.00e+00	1056.00
IUUC-Mvi-060337	Microbotryum violaceum	41.73	1.00e-107	383.00
IUUC-Mmr-061619	Microcebus murinus	91.86	0.00e+00	1048.00
IUUC-Mdo-062160	Monodelphis domestica	92.22	0.00e+00	1040.00
IUUC-Mmu-063406	Mus musculus	90.78	0.00e+00	1038.00
IUUC-Mac-064518	Musa acuminata	45.83	4.00e-121	428.00
IUUC-Mpu-066326	Mustela putorius furo	92.32	0.00e+00	1000.00
IUUC-Mlu-067968	Myotis lucifugus	90.91	0.00e+00	962.00
IUUC-Nfi-068493	Neosartorya fischeri	60.07	2.00e-101	363.00
IUUC-Ncr-068665	Neurospora crassa	41.96	2.00e-107	383.00
IUUC-Nle-070158	Nomascus leucogenys	91.86	0.00e+00	1053.00
IUUC-Opr-070272	Ochotona princeps	73.02	0.00e+00	780.00
IUUC-Ont-071395	Oreochromis niloticus	87.25	0.00e+00	998.00
IUUC-Oan-073322	Ornithorhynchus anatinus	68.85	0.00e+00	745.00
IUUC-Ocu-074188	Oryctolagus cuniculus	73.59	0.00e+00	781.00
IUUC-Oba-075436	Oryza barthii	45.98	4.00e-125	441.00
IUUC-Obr-076507	Oryza brachyantha	46.77	3.00e-125	441.00
IUUC-Ogl-077718	Oryza glaberrima	46.84	1.00e-124	439.00
IUUC-Ogu-078349	Oryza glumaepatula	45.98	6.00e-125	441.00
IUUC-Oin-079889	Oryza indica	46.39	2.00e-125	442.00
IUUC-Olo-080521	Oryza longistaminata	45.98	6.00e-125	441.00
IUUC-Ome-081630	Oryza meridionalis	45.78	1.00e-124	439.00
IUUC-Oni-082211	Oryza nivara	45.98	4.00e-125	441.00
IUUC-Opu-083617	Oryza punctata	45.89	7.00e-125	440.00
IUUC-Oru-084252	Oryza rufipogon	45.98	5.00e-125	441.00
IUUC-Osa-085548	Oryza sativa	45.98	5.00e-125	441.00
IUUC-Ola-087169	Oryzias latipes	85.46	0.00e+00	978.00
IUUC-Olu-087861	Ostreococcus lucimarinus	43.39	8.00e-117	413.00
IUUC-Oga-088003	Otolemur garnettii	75.27	0.00e+00	789.00
IUUC-Oar-089933	Ovis aries	75.63	0.00e+00	789.00
IUUC-Ptr-090741	Pan troglodytes	92.04	0.00e+00	1055.00
IUUC-Pan-092526	Papio anubis	75.27	0.00e+00	788.00
IUUC-Psi-094034	Pelodiscus sinensis	74.68	0.00e+00	782.00
IUUC-Pno-095030	Phaeosphaeria nodorum	60.79	4.00e-104	371.00
IUUC-Ppa-095615	Physcomitrella patens	49.78	1.00e-122	433.00
IUUC-Pfo-096295	Poecilia formosa	86.89	0.00e+00	992.00
IUUC-Pab-098023	Pongo abelii	92.04	0.00e+00	1055.00
IUUC-Pop-100042	Populus trichocarpa	47.46	7.00e-128	450.00
IUUC-Pca-101104	Procavia capensis	78.13	9.00e-174	603.00
IUUC-Ppe-101642	Prunus persica	48.42	6.00e-125	441.00
IUUC-Pva-102470	Pteropus vampyrus	91.32	0.00e+00	1041.00
IUUC-Pgr-103406	Puccinia graminis	58.97	5.00e-91	328.00
IUUC-Ptt-103713	Puccinia triticina	37.02	2.00e-79	289.00
IUUC-Pte-104259	Pyrenophora teres	60.87	5.00e-105	375.00
IUUC-Pyt-104752	Pyrenophora triticirepentis	61.23	9.00e-106	377.00
IUUC-Rno-104960	Rattus norvegicus	91.86	0.00e+00	1055.00
IUUC-Sce-106290	Saccharomyces cerevisiae	42.46	6.00e-117	414.00
IUUC-Sha-107603	Sarcophilus harrisii	74.73	0.00e+00	786.00
IUUC-Sja-107772	Schizosaccharomyces japonicus	40.34	1.00e-110	393.00
IUUC-Spo-108202	Schizosaccharomyces pombe	42.13	1.00e-107	383.00
IUUC-Ssl-108535	Sclerotinia sclerotiorum	47.52	7.00e-104	371.00
IUUC-Smo-109309	Selaginella moellendorffii	46.23	1.00e-123	436.00
IUUC-Sit-109745	Setaria italica	47.67	2.00e-126	445.00
IUUC-Sly-110890	Solanum lycopersicum	47.49	6.00e-126	444.00
IUUC-Stu-112144	Solanum tuberosum	45.51	5.00e-118	417.00
IUUC-Sar-113521	Sorex araneus	64.94	0.00e+00	631.00
IUUC-Sbi-114764	Sorghum bicolor	47.48	2.00e-127	448.00
IUUC-Sre-115141	Sporisorium reilianum	66.54	2.00e-114	406.00
IUUC-Ssc-115732	Sus scrofa	74.19	0.00e+00	759.00
IUUC-Tgu-117190	Taeniopygia guttata	75.09	0.00e+00	781.00
IUUC-Tru-118735	Takifugu rubripes	86.54	0.00e+00	991.00
IUUC-Tsy-119503	Tarsius syrichta	88.65	0.00e+00	940.00
IUUC-Tni-119880	Tetraodon nigroviridis	86.20	0.00e+00	997.00
IUUC-Tca-121386	Theobroma cacao	47.56	2.00e-127	449.00
IUUC-Tre-122070	Trichoderma reesei	49.73	3.00e-103	369.00
IUUC-Tvi-122305	Trichoderma virens	49.46	3.00e-102	365.00
IUUC-Tae-123515	Triticum aestivum	47.23	4.00e-125	441.00
IUUC-Tur-126416	Triticum urartu	45.87	7.00e-124	437.00
IUUC-Tme-127174	Tuber melanosporum	40.00	4.00e-67	248.00
IUUC-Tbe-127791	Tupaia belangeri	86.09	6.00e-113	400.00
IUUC-Ttr-129224	Tursiops truncatus	73.37	0.00e+00	781.00
IUUC-Uma-129372	Ustilago maydis	66.54	8.00e-114	404.00
IUUC-Vda-129819	Verticillium dahliae	53.96	4.00e-85	308.00
IUUC-Vpa-130220	Vicugna pacos	91.92	0.00e+00	996.00
IUUC-Vvi-131649	Vitis vinifera	47.37	2.00e-125	442.00
IUUC-Xtr-132954	Xenopus tropicalis	92.78	0.00e+00	1050.00
IUUC-Xma-134119	Xiphophorus maculatus	86.71	0.00e+00	990.00
IUUC-Yli-134422	Yarrowia lipolytica	45.49	5.00e-119	421.00
IUUC-Zma-135621	Zea mays	61.68	1.00e-119	424.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence