iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071961

Ensembl Protein ID

ENSONIP00000024730.1

UniProt Accession

I3KUD4; I3KUD4_ORENI

Genbank Protein ID

ENSONIP00000024730

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

AERX01002154

Gene Name

LOC100698953

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000019644.1	ENSONIT00000024751.1	ENSONIP00000024730.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.60e-88	296.0	166	507

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtC+mN+++Q+L+++p lr+++l+ +++k++ +    ++ +l++++ +lf+e+++++++   p +ll+ +++ a+++ gyeqq
   Q: 166  GLINLGNTCFMNCIVQALTHTPLLRDFFLS-DRHKCEMQ----SNSCLVCEMSQLFQEFYSGHRSPHIPFRLLHLVWTHARHLAGYEQQ 249
           9*****************************.99999865....689******************************************* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           Da+Efl   ld l++++k                  ++ ++ +++++ +++i+++F g l  +++c     vs++ +pf+d+sl++pg+
   Q: 250  DAHEFLIAALDVLHRHCKD-----------------DNGKKANNPNHCNCIIDQIFTGGLLFKLICYVPSGVSTTIDPFWDISLDLPGS 321
           *****************22.................3335678899999**************************************** PP
   S: 180  eetkke....................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrek 248
           ++   +                    +l+dcL+ ft++e+l ++ k++c+ c+++qe++k+l++kklP v ++hLkRf  +++ k r+k
   Q: 322  STPFWPlspggdgsalngeshttgatTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRF--EHSAKLRRK 408
           *87777************************************************************************..5666899** PP
   S: 249  inkkvefpleLdlspfctspeekqke............kkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevlee 325
           i+++v+fpleLd++pf++s++e+  +            ++kY+L+avv+H+G+l+sGHY+++++++k++W+++dD  +t+ + ++vl  
   Q: 409  ITTYVSFPLELDMTPFMASSKESRMNgqyqqtvdpfnnDNKYSLFAVVNHQGTLESGHYTTFIRQHKDQWFKCDDAIITKASIKDVLD- 496
           ******************97777666899999999999**************************************************. PP
   S: 326  tgstaYvlfYkrr 338
             s++Y+lfY+++
   Q: 497  --SEGYLLFYHKQ 507
           ..********985 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

PDAVTTMSPA GCPHVNGFKV DNWKQNLRVI YQCFVWSGSA ETRKRKAKSC ICHMCGAHLN 60
RLHSCLYCVF FACFAKKHIH EHAKSKRHNL AIDLLYGGIY CFMCQDYIYD KEMEQIAKEE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGGATGCTG TGACTACCAT GAGTCCCGCA GGCTGCCCCC ATGTCAACGG CTTCAAAGTG 60
GACAACTGGA AGCAGAACCT GAGGGTCATT TATCAGTGTT TCGTGTGGAG TGGTTCAGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000393	Aegilops tauschii	35.71	4.00e-58	219.00
IUUC-Aml-001343	Ailuropoda melanoleuca	88.78	0.00e+00	962.00
IUUC-Atr-002653	Amborella trichopoda	37.55	7.00e-95	341.00
IUUC-Apl-003433	Anas platyrhynchos	90.29	0.00e+00	907.00
IUUC-Aca-005347	Anolis carolinensis	87.59	0.00e+00	969.00
IUUC-Aly-006565	Arabidopsis lyrata	36.12	2.00e-70	260.00
IUUC-Ath-007536	Arabidopsis thaliana	36.12	1.00e-70	260.00
IUUC-Ago-007811	Ashbya gossypii	29.30	1.00e-48	187.00
IUUC-Acl-008124	Aspergillus clavatus	30.56	3.00e-55	209.00
IUUC-Afl-008464	Aspergillus flavus	32.14	2.00e-51	196.00
IUUC-Afu-008912	Aspergillus fumigatus	29.91	5.00e-54	205.00
IUUC-Ani-009168	Aspergillus nidulans	31.00	3.00e-54	206.00
IUUC-Ang-009694	Aspergillus niger	30.86	3.00e-52	199.00
IUUC-Ate-010382	Aspergillus terreus	31.90	3.00e-51	196.00
IUUC-Ame-011253	Astyanax mexicanus	87.08	0.00e+00	851.00
IUUC-Bgr-012150	Blumeria graminis	29.49	2.00e-42	167.00
IUUC-Bta-013303	Bos taurus	88.89	0.00e+00	967.00
IUUC-Bci-013604	Botrytis cinerea	30.75	4.00e-52	199.00
IUUC-Bdi-014171	Brachypodium distachyon	34.68	1.00e-71	264.00
IUUC-Bol-016509	Brassica oleracea	37.26	2.00e-71	264.00
IUUC-Bra-016962	Brassica rapa	36.36	7.00e-71	261.00
IUUC-Cja-019283	Callithrix jacchus	91.51	0.00e+00	816.00
IUUC-Cfa-021239	Canis familiaris	90.45	0.00e+00	902.00
IUUC-Cpo-022354	Cavia porcellus	89.08	0.00e+00	966.00
IUUC-Csa-023145	Chlorocebus sabaeus	89.67	0.00e+00	974.00
IUUC-Cho-024938	Choloepus hoffmanni	89.66	6.00e-63	234.00
IUUC-Cin-025109	Ciona intestinalis	56.65	2.00e-118	419.00
IUUC-Csv-026214	Ciona savignyi	54.48	4.00e-173	601.00
IUUC-Cgl-026457	Colletotrichum gloeosporioides	30.84	3.00e-51	196.00
IUUC-Cne-027085	Cryptococcus neoformans	32.19	7.00e-61	228.00
IUUC-Dre-027433	Danio rerio	93.99	0.00e+00	927.00
IUUC-Dno-030095	Dasypus novemcinctus	91.26	0.00e+00	905.00
IUUC-Dor-030832	Dipodomys ordii	84.02	2.00e-95	342.00
IUUC-Dse-031415	Dothistroma septosporum	29.41	3.00e-58	219.00
IUUC-Dme-032074	Drosophila melanogaster	49.91	2.00e-134	473.00
IUUC-Ete-033175	Echinops telfairi	71.05	0.00e+00	641.00
IUUC-Eca-033736	Equus caballus	90.19	0.00e+00	896.00
IUUC-Eeu-034814	Erinaceus europaeus	93.81	3.00e-117	415.00
IUUC-Fca-035861	Felis catus	90.83	0.00e+00	900.00
IUUC-Fal-037645	Ficedula albicollis	90.34	0.00e+00	892.00
IUUC-Fox-038046	Fusarium oxysporum	30.80	3.00e-52	199.00
IUUC-Fso-038321	Fusarium solani	31.35	2.00e-52	199.00
IUUC-Gmo-038474	Gadus morhua	92.91	2.00e-166	578.00
IUUC-Ggr-040044	Gaeumannomyces graminis	30.39	8.00e-50	191.00
IUUC-Gga-040624	Gallus gallus	90.10	0.00e+00	979.00
IUUC-Gac-042197	Gasterosteus aculeatus	90.52	0.00e+00	960.00
IUUC-Gma-042897	Glycine max	31.64	3.00e-82	299.00
IUUC-Ggo-044409	Gorilla gorilla	89.47	0.00e+00	974.00
IUUC-Hsa-046521	Homo sapiens	89.47	0.00e+00	974.00
IUUC-Hvu-047739	Hordeum vulgare	37.95	1.00e-65	243.00
IUUC-Itr-048375	Ictidomys tridecemlineatus	89.47	0.00e+00	973.00
IUUC-Kpa-049135	Komagataella pastoris	34.48	5.00e-65	241.00
IUUC-Lch-050537	Latimeria chalumnae	92.72	0.00e+00	994.00
IUUC-Lpe-050969	Leersia perrieri	36.98	3.00e-68	252.00
IUUC-Loc-052765	Lepisosteus oculatus	82.67	0.00e+00	895.00
IUUC-Lma-053105	Leptosphaeria maculans	31.91	3.00e-62	232.00
IUUC-Laf-053571	Loxodonta africana	91.68	0.00e+00	905.00
IUUC-Mcc-055166	Macaca mulatta	89.67	0.00e+00	974.00
IUUC-Mor-057103	Magnaporthe oryzae	31.40	1.00e-54	207.00
IUUC-Mpo-057621	Magnaporthe poae	30.02	5.00e-50	192.00
IUUC-Mtr-057769	Medicago truncatula	33.90	3.00e-83	303.00
IUUC-Mla-059185	Melampsora laricipopulina	30.25	2.00e-40	160.00
IUUC-Mga-059709	Meleagris gallopavo	90.29	0.00e+00	907.00
IUUC-Mvi-060530	Microbotryum violaceum	32.64	1.00e-57	217.00
IUUC-Mmr-060988	Microcebus murinus	89.08	0.00e+00	973.00
IUUC-Mdo-063065	Monodelphis domestica	92.72	0.00e+00	992.00
IUUC-Mmu-063829	Mus musculus	89.28	0.00e+00	972.00
IUUC-Mac-065419	Musa acuminata	38.62	5.00e-68	252.00
IUUC-Mpu-066687	Mustela putorius furo	88.30	0.00e+00	959.00
IUUC-Mlu-067330	Myotis lucifugus	78.23	0.00e+00	839.00
IUUC-Nfi-068423	Neosartorya fischeri	30.13	1.00e-54	207.00
IUUC-Ncr-068809	Neurospora crassa	30.22	1.00e-53	204.00
IUUC-Nle-069261	Nomascus leucogenys	85.58	0.00e+00	920.00
IUUC-Opr-070469	Ochotona princeps	73.52	2.00e-180	625.00
IUUC-Oan-073565	Ornithorhynchus anatinus	83.63	0.00e+00	880.00
IUUC-Ocu-074435	Oryctolagus cuniculus	89.20	0.00e+00	944.00
IUUC-Oba-075688	Oryza barthii	34.42	6.00e-70	258.00
IUUC-Obr-076652	Oryza brachyantha	39.16	1.00e-68	253.00
IUUC-Ogl-077910	Oryza glaberrima	34.14	8.00e-73	268.00
IUUC-Ogu-078479	Oryza glumaepatula	34.14	8.00e-73	268.00
IUUC-Oin-079697	Oryza indica	37.25	7.00e-70	258.00
IUUC-Olo-080811	Oryza longistaminata	38.70	1.00e-48	186.00
IUUC-Ome-081706	Oryza meridionalis	34.14	3.00e-72	266.00
IUUC-Oni-083070	Oryza nivara	33.73	9.00e-73	268.00
IUUC-Opu-083605	Oryza punctata	37.50	9.00e-62	230.00
IUUC-Oru-084522	Oryza rufipogon	34.14	8.00e-73	268.00
IUUC-Osa-085351	Oryza sativa	37.23	5.00e-71	262.00
IUUC-Ola-086743	Oryzias latipes	89.75	0.00e+00	764.00
IUUC-Olu-087695	Ostreococcus lucimarinus	30.00	5.00e-46	178.00
IUUC-Oga-089131	Otolemur garnettii	86.20	0.00e+00	960.00
IUUC-Oar-089319	Ovis aries	90.38	0.00e+00	894.00
IUUC-Ptr-090783	Pan troglodytes	91.04	0.00e+00	903.00
IUUC-Pan-092927	Papio anubis	89.67	0.00e+00	973.00
IUUC-Psi-093670	Pelodiscus sinensis	90.48	0.00e+00	907.00
IUUC-Pma-094323	Petromyzon marinus	67.01	0.00e+00	680.00
IUUC-Pno-095141	Phaeosphaeria nodorum	30.12	6.00e-53	201.00
IUUC-Ppa-095413	Physcomitrella patens	32.67	8.00e-75	275.00
IUUC-Pfo-096473	Poecilia formosa	96.64	0.00e+00	1030.00
IUUC-Pab-097612	Pongo abelii	89.67	0.00e+00	975.00
IUUC-Pop-099558	Populus trichocarpa	34.15	4.00e-86	312.00
IUUC-Pca-100329	Procavia capensis	78.42	0.00e+00	843.00
IUUC-Ppe-102020	Prunus persica	35.52	2.00e-92	333.00
IUUC-Pva-102721	Pteropus vampyrus	74.37	0.00e+00	783.00
IUUC-Pgr-103657	Puccinia graminis	27.98	8.00e-36	145.00
IUUC-Pte-104340	Pyrenophora teres	32.80	4.00e-59	222.00
IUUC-Pyt-104782	Pyrenophora triticirepentis	35.39	1.00e-63	237.00
IUUC-Rno-105247	Rattus norvegicus	89.28	0.00e+00	973.00
IUUC-Sce-106247	Saccharomyces cerevisiae	30.37	9.00e-46	177.00
IUUC-Sha-107538	Sarcophilus harrisii	93.09	2.00e-120	424.00
IUUC-Sja-107656	Schizosaccharomyces japonicus	33.74	9.00e-63	234.00
IUUC-Spo-108226	Schizosaccharomyces pombe	31.51	3.00e-58	219.00
IUUC-Ssl-108531	Sclerotinia sclerotiorum	30.88	9.00e-49	188.00
IUUC-Smo-109310	Selaginella moellendorffii	34.88	6.00e-84	305.00
IUUC-Sit-109716	Setaria italica	34.07	3.00e-76	279.00
IUUC-Sly-111077	Solanum lycopersicum	36.36	7.00e-78	285.00
IUUC-Stu-112203	Solanum tuberosum	38.80	4.00e-70	258.00
IUUC-Sar-113174	Sorex araneus	73.63	0.00e+00	746.00
IUUC-Sbi-114205	Sorghum bicolor	33.73	2.00e-75	276.00
IUUC-Sre-115195	Sporisorium reilianum	27.26	2.00e-52	201.00
IUUC-Ssc-115315	Sus scrofa	77.67	0.00e+00	842.00
IUUC-Tgu-116938	Taeniopygia guttata	93.18	0.00e+00	917.00
IUUC-Tru-118304	Takifugu rubripes	93.55	0.00e+00	1027.00
IUUC-Tsy-119431	Tarsius syrichta	79.91	0.00e+00	759.00
IUUC-Tni-120661	Tetraodon nigroviridis	96.88	0.00e+00	1043.00
IUUC-Tca-121716	Theobroma cacao	33.00	3.00e-83	303.00
IUUC-Tre-122139	Trichoderma reesei	30.82	2.00e-50	193.00
IUUC-Tvi-122599	Trichoderma virens	30.51	1.00e-52	201.00
IUUC-Tae-125608	Triticum aestivum	34.62	1.00e-79	291.00
IUUC-Tme-127115	Tuber melanosporum	35.43	1.00e-74	273.00
IUUC-Ttr-129006	Tursiops truncatus	78.59	0.00e+00	828.00
IUUC-Uma-129455	Ustilago maydis	28.85	7.00e-58	219.00
IUUC-Vvi-131477	Vitis vinifera	34.82	1.00e-75	277.00
IUUC-Xtr-132444	Xenopus tropicalis	89.10	0.00e+00	974.00
IUUC-Xma-133514	Xiphophorus maculatus	92.77	0.00e+00	1009.00
IUUC-Yli-134357	Yarrowia lipolytica	27.11	1.00e-44	174.00
IUUC-Zma-134945	Zea mays	33.20	3.00e-73	269.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence