iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-026886

Ensembl Protein ID

AAW40874

UniProt Accession

P0CQ66; Q560G8; Q5KPG8; RAD5_CRYNJ

Genbank Protein ID

AAW40874.1

Protein Name

DNA repair protein RAD5

Genbank Nucleotide ID

AE017341

Gene Name

RAD5; CNA02850

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CNA02850	AAW40874	AAW40874

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	30.61	2.00e-113	405.00	IUUC-Sce-106396
E3 activity/RING/RING	34.73	2.00e-137	485.00	IUUC-Spo-108026

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Cryptococcus neoformans

Functional Description
(View)

Probable helicase, member of the UBC2/RAD6 epistasis group. Functions with DNA repair protein RAD18 in error-free postreplication DNA repair. Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats. Seems to be involved in maintaining a balance which acts in favor of error-prone non-homologous joining during DNA double-strand breaks repairs (By similarity).

Protein Sequence
(Fasta)

MSAEASPETG RFRTKSSPEL FFPATDSEGE EQNDVPLTIV HPTQSTSSKF SINIASSSRP 60
QHGITTGDFE ATSQTSAHDN VDDDFSIVGH NPASSHPQGT IVAPRRKRSL QQAHSHHSSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTTCCTTCC TCACCTCCAC GCCATGAGCG CCGAAGCCTC TCCAGAAACG GGACGTTTTA 60
GGACAAAGTC TTCCCCAGAA CTTTTCTTCC CTGCTACGGA CTCAGAAGGT GAAGAGCAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0227--DNA damage
KW-0234--DNA repair
KW-0238--DNA-binding
KW-0347--Helicase
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR014905--HIRAN
IPR027417--P-loop_NTPase
IPR000330--SNF2_N
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS50089--ZF_RING_2

Pfam

PF00271--Helicase_C
PF08797--HIRAN
PF00176--SNF2_N
PF00097--zf-C3HC4

SMART

SM00487--DEXDc
SM00490--HELICc
SM00910--HIRAN

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0004386--F:helicase activity
GO:0008270--F:zinc ion binding
GO:0006281--P:DNA repair

KEGG

cne:CNA02850

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000167	Aegilops tauschii	32.63	2.00e-132	464.00
IUUC-Atr-003058	Amborella trichopoda	33.27	4.00e-134	470.00
IUUC-Aly-005600	Arabidopsis lyrata	33.33	2.00e-144	504.00
IUUC-Ath-007079	Arabidopsis thaliana	33.81	6.00e-141	493.00
IUUC-Ago-007997	Ashbya gossypii	31.06	5.00e-101	360.00
IUUC-Acl-008022	Aspergillus clavatus	33.15	1.00e-158	552.00
IUUC-Afl-008514	Aspergillus flavus	33.39	2.00e-162	565.00
IUUC-Afu-009055	Aspergillus fumigatus	33.24	1.00e-159	555.00
IUUC-Ani-009340	Aspergillus nidulans	33.33	1.00e-154	538.00
IUUC-Ang-009785	Aspergillus niger	34.49	2.00e-161	561.00
IUUC-Aor-010158	Aspergillus oryzae	33.39	2.00e-162	565.00
IUUC-Ate-010536	Aspergillus terreus	31.91	1.00e-145	508.00
IUUC-Bgr-012147	Blumeria graminis	32.87	8.00e-157	546.00
IUUC-Bci-013741	Botrytis cinerea	34.46	3.00e-167	580.00
IUUC-Bdi-014646	Brachypodium distachyon	31.95	1.00e-131	462.00
IUUC-Bol-015995	Brassica oleracea	33.33	5.00e-141	493.00
IUUC-Bra-017004	Brassica rapa	35.92	4.00e-133	467.00
IUUC-Cre-022824	Chlamydomonas reinhardtii	30.19	2.00e-63	236.00
IUUC-Cgl-026606	Colletotrichum gloeosporioides	34.56	6.00e-164	570.00
IUUC-Cme-027110	Cyanidioschyzon merolae	31.96	8.00e-96	343.00
IUUC-Dse-031471	Dothistroma septosporum	34.16	7.00e-165	573.00
IUUC-Fox-038039	Fusarium oxysporum	34.15	4.00e-159	553.00
IUUC-Fso-038179	Fusarium solani	34.40	2.00e-165	574.00
IUUC-Ggr-039735	Gaeumannomyces graminis	34.86	6.00e-165	573.00
IUUC-Gma-042995	Glycine max	33.13	2.00e-135	474.00
IUUC-Hvu-047747	Hordeum vulgare	32.36	8.00e-129	452.00
IUUC-Kpa-049087	Komagataella pastoris	30.01	1.00e-104	372.00
IUUC-Lpe-051123	Leersia perrieri	32.05	2.00e-132	464.00
IUUC-Lma-052956	Leptosphaeria maculans	36.17	3.00e-177	613.00
IUUC-Mor-057210	Magnaporthe oryzae	36.14	1.00e-169	588.00
IUUC-Mpo-057407	Magnaporthe poae	35.08	4.00e-174	603.00
IUUC-Mtr-058565	Medicago truncatula	31.80	3.00e-129	454.00
IUUC-Mla-058867	Melampsora laricipopulina	36.66	3.00e-93	334.00
IUUC-Mga-059553	Meleagris gallopavo	41.04	2.00e-38	153.00
IUUC-Mvi-060322	Microbotryum violaceum	35.92	6.00e-129	453.00
IUUC-Mac-064548	Musa acuminata	29.38	3.00e-110	391.00
IUUC-Nfi-068354	Neosartorya fischeri	33.30	7.00e-159	553.00
IUUC-Ncr-068844	Neurospora crassa	35.30	2.00e-172	597.00
IUUC-Oba-075316	Oryza barthii	31.49	8.00e-125	439.00
IUUC-Obr-076403	Oryza brachyantha	32.31	3.00e-127	447.00
IUUC-Ogl-077573	Oryza glaberrima	32.93	3.00e-133	467.00
IUUC-Ogu-078083	Oryza glumaepatula	31.51	6.00e-128	450.00
IUUC-Oin-079146	Oryza indica	32.93	5.00e-133	466.00
IUUC-Olo-080615	Oryza longistaminata	32.12	2.00e-131	461.00
IUUC-Ome-081448	Oryza meridionalis	31.71	8.00e-121	426.00
IUUC-Oni-082773	Oryza nivara	31.69	2.00e-127	448.00
IUUC-Opu-083675	Oryza punctata	31.95	3.00e-129	454.00
IUUC-Oru-084543	Oryza rufipogon	31.69	1.00e-126	446.00
IUUC-Osa-085686	Oryza sativa	32.90	1.00e-125	442.00
IUUC-Pno-094916	Phaeosphaeria nodorum	37.30	2.00e-172	597.00
IUUC-Ppa-095877	Physcomitrella patens	35.58	1.00e-130	459.00
IUUC-Pop-099537	Populus trichocarpa	32.99	9.00e-137	479.00
IUUC-Ppe-101820	Prunus persica	35.11	6.00e-105	373.00
IUUC-Pgr-103454	Puccinia graminis	33.99	3.00e-162	564.00
IUUC-Ptt-103829	Puccinia triticina	33.95	9.00e-131	459.00
IUUC-Pte-104242	Pyrenophora teres	35.85	9.00e-174	602.00
IUUC-Pyt-104728	Pyrenophora triticirepentis	36.42	9.00e-174	602.00
IUUC-Sce-106396	Saccharomyces cerevisiae	30.91	1.00e-107	382.00
IUUC-Sja-107985	Schizosaccharomyces japonicus	34.23	8.00e-143	499.00
IUUC-Spo-108026	Schizosaccharomyces pombe	34.73	1.00e-138	486.00
IUUC-Ssl-108388	Sclerotinia sclerotiorum	35.02	3.00e-167	580.00
IUUC-Sit-110076	Setaria italica	33.03	4.00e-134	470.00
IUUC-Sly-111031	Solanum lycopersicum	33.47	2.00e-140	491.00
IUUC-Stu-112600	Solanum tuberosum	33.13	2.00e-140	491.00
IUUC-Sbi-113927	Sorghum bicolor	31.78	2.00e-127	447.00
IUUC-Sre-115131	Sporisorium reilianum	36.66	0.00e+00	662.00
IUUC-Tca-121137	Theobroma cacao	31.83	9.00e-137	479.00
IUUC-Tre-121896	Trichoderma reesei	37.00	1.00e-169	588.00
IUUC-Tvi-122597	Trichoderma virens	34.71	1.00e-169	588.00
IUUC-Tae-125934	Triticum aestivum	32.89	1.00e-133	469.00
IUUC-Tur-125999	Triticum urartu	35.38	5.00e-126	443.00
IUUC-Tme-126953	Tuber melanosporum	34.77	6.00e-166	576.00
IUUC-Uma-129629	Ustilago maydis	37.69	0.00e+00	697.00
IUUC-Vda-129849	Verticillium dahliae	35.49	2.00e-154	538.00
IUUC-Vvi-131508	Vitis vinifera	32.44	3.00e-132	464.00
IUUC-Yli-134588	Yarrowia lipolytica	29.88	3.00e-117	414.00
IUUC-Zma-135801	Zea mays	34.91	9.00e-118	416.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence