iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Rno-105039

Ensembl Protein ID

ENSRNOP00000027134.6

UniProt Accession

M9MMM8; M9MMM8_RAT

Genbank Protein ID

ENSRNOP00000027134

Protein Name

Serine/threonine-protein kinase BRSK2

Genbank Nucleotide ID

AABR07006037

Gene Name

Brsk2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000020021.8	ENSRNOT00000027134.6	ENSRNOP00000027134.6

Annotation

Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	83.83	0.00e+00	1107.00	IUUC-Hsa-046912

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

GLSPTGLVKL GIHCVTCQKV AIKIVNREKL SESVLMKVER EIAILKLIEH PHVLKLHDVY 60
ENKKYLYLVL EHVSGGELFD YLVKKGRLTP KEARKFFRQI ISALDFCHSH SICHRDLKPE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCCTTTCTC CTACAGGCTT GGTGAAACTG GGAATCCACT GTGTCACCTG CCAGAAGGTC 60
GCCATCAAAA TCGTCAACCG TGAGAAGCTC AGTGAGTCGG TGCTGATGAA GGTGAGGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005813--C:centrosome
GO:0005783--C:endoplasmic reticulum
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0050321--F:tau-protein kinase activity
GO:0031532--P:actin cytoskeleton reorganization
GO:0007409--P:axonogenesis
GO:0036503--P:ERAD pathway
GO:0030010--P:establishment of cell polarity
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:0070059--P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0018105--P:peptidyl-serine phosphorylation
GO:0061178--P:regulation of insulin secretion involved in cellular response to glucose stimulus

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003374	Anas platyrhynchos	78.48	0.00e+00	991.00
IUUC-Bta-012608	Bos taurus	82.44	0.00e+00	1052.00
IUUC-Cel-018416	Caenorhabditis elegans	65.93	5.00e-146	511.00
IUUC-Cja-019882	Callithrix jacchus	82.69	0.00e+00	1050.00
IUUC-Cpo-021604	Cavia porcellus	83.69	0.00e+00	1080.00
IUUC-Csv-025996	Ciona savignyi	53.58	1.00e-154	540.00
IUUC-Dre-028706	Danio rerio	71.09	0.00e+00	879.00
IUUC-Dme-031685	Drosophila melanogaster	75.07	3.00e-153	535.00
IUUC-Eca-033483	Equus caballus	82.54	0.00e+00	1006.00
IUUC-Fal-037499	Ficedula albicollis	78.97	0.00e+00	985.00
IUUC-Gmo-039305	Gadus morhua	83.90	0.00e+00	661.00
IUUC-Gac-042120	Gasterosteus aculeatus	85.79	0.00e+00	846.00
IUUC-Hsa-046912	Homo sapiens	82.70	0.00e+00	1072.00
IUUC-Itr-048825	Ictidomys tridecemlineatus	84.40	0.00e+00	1073.00
IUUC-Mcc-055306	Macaca mulatta	82.82	0.00e+00	1073.00
IUUC-Mor-057261	Magnaporthe oryzae	39.94	1.00e-74	275.00
IUUC-Mga-059357	Meleagris gallopavo	78.99	0.00e+00	987.00
IUUC-Mmr-061711	Microcebus murinus	70.56	0.00e+00	812.00
IUUC-Mdo-062356	Monodelphis domestica	68.36	0.00e+00	753.00
IUUC-Mmu-063511	Mus musculus	85.33	0.00e+00	1128.00
IUUC-Mlu-068102	Myotis lucifugus	77.71	0.00e+00	697.00
IUUC-Ont-072425	Oreochromis niloticus	81.24	0.00e+00	887.00
IUUC-Ola-086969	Oryzias latipes	75.11	0.00e+00	928.00
IUUC-Pan-092910	Papio anubis	82.70	0.00e+00	1072.00
IUUC-Psi-093857	Pelodiscus sinensis	72.50	0.00e+00	760.00
IUUC-Pfo-097195	Poecilia formosa	81.24	0.00e+00	887.00
IUUC-Sha-107449	Sarcophilus harrisii	90.00	0.00e+00	682.00
IUUC-Tgu-117372	Taeniopygia guttata	76.78	0.00e+00	992.00
IUUC-Tru-118645	Takifugu rubripes	77.36	0.00e+00	946.00
IUUC-Tni-120483	Tetraodon nigroviridis	65.20	0.00e+00	796.00
IUUC-Tme-126887	Tuber melanosporum	47.78	1.00e-77	283.00
IUUC-Xtr-132457	Xenopus tropicalis	76.68	0.00e+00	970.00
IUUC-Xma-134021	Xiphophorus maculatus	73.68	0.00e+00	916.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence