iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037236

Ensembl Protein ID

ENSFALP00000002437.1

UniProt Accession

U3JI33; U3JI33_FICAL

Genbank Protein ID

ENSFALP00000002437

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01001130

Gene Name

ITSN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000002323.1	ENSFALT00000002449.1	ENSFALP00000002437.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.80e-69	227.9	1141	1192

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +v+ +ydy+aqnddeL + kG +++v+    +d +W+kg  e +g  GlfP+n+v+
   Q: 1141 QVIGMYDYSAQNDDELAFSKGQIITVL--SREDPDWWKG--EVNGHVGLFPSNYVK 1192
           56779**********************..899*******..9*************8 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MAQFPTPFGG NLDIWAITVE ERAKHDQQFH SLKPTAGFIT GDQARNFFFQ SGLPQPVLAQ 60
IWALADMNND GRMDPLEFSI AMKLIKLKLQ GYQLPAALPP VMKQPPLALP AAPGFGLGGI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTCAGT TTCCAACACC TTTTGGGGGT AAGTGGTTTC TGGTGTGCTT TGAACTGTTC 60
CTGTGTGCAA AACCTTGGCA TAAACGTGTT CCTTCCCAAG AGTTTTTTAG GGGAGTGTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR001331--GDS_CDC24_CS
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS00741--DH_1
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030139--C:endocytic vesicle
GO:0030027--C:lamellipodium
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0019209--F:kinase activator activity
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000722	Aegilops tauschii	41.67	2.00e-14	75.50
IUUC-Aml-001218	Ailuropoda melanoleuca	87.76	0.00e+00	2248.00
IUUC-Apl-003335	Anas platyrhynchos	94.02	0.00e+00	2330.00
IUUC-Aca-005130	Anolis carolinensis	89.01	0.00e+00	2229.00
IUUC-Ago-007935	Ashbya gossypii	36.09	1.00e-14	74.70
IUUC-Ang-009722	Aspergillus niger	31.45	6.00e-16	79.30
IUUC-Aor-010021	Aspergillus oryzae	30.00	2.00e-19	90.50
IUUC-Ame-011878	Astyanax mexicanus	77.09	0.00e+00	1940.00
IUUC-Bta-012863	Bos taurus	89.83	0.00e+00	2234.00
IUUC-Bci-013975	Botrytis cinerea	47.62	6.00e-14	71.60
IUUC-Bdi-014016	Brachypodium distachyon	40.86	1.00e-14	75.50
IUUC-Bra-017706	Brassica rapa	31.29	6.00e-13	69.70
IUUC-Cja-019012	Callithrix jacchus	89.54	0.00e+00	2188.00
IUUC-Cfa-020171	Canis familiaris	88.35	0.00e+00	2256.00
IUUC-Cpo-021352	Cavia porcellus	82.76	0.00e+00	2635.00
IUUC-Cre-023011	Chlamydomonas reinhardtii	30.39	4.00e-01	28.90
IUUC-Cho-024969	Choloepus hoffmanni	76.96	0.00e+00	1763.00
IUUC-Csv-026290	Ciona savignyi	59.08	0.00e+00	792.00
IUUC-Cgl-026405	Colletotrichum gloeosporioides	49.25	9.00e-14	71.20
IUUC-Cme-027247	Cyanidioschyzon merolae	25.43	4.00e-11	62.80
IUUC-Dre-028623	Danio rerio	77.63	0.00e+00	1959.00
IUUC-Dno-030044	Dasypus novemcinctus	87.41	0.00e+00	2234.00
IUUC-Dor-030272	Dipodomys ordii	82.97	0.00e+00	1950.00
IUUC-Ete-032927	Echinops telfairi	97.00	0.00e+00	1027.00
IUUC-Eca-033469	Equus caballus	87.99	0.00e+00	2210.00
IUUC-Eeu-034977	Erinaceus europaeus	82.25	0.00e+00	995.00
IUUC-Fca-036419	Felis catus	89.09	0.00e+00	2252.00
IUUC-Gmo-039632	Gadus morhua	70.35	0.00e+00	1706.00
IUUC-Ggr-040121	Gaeumannomyces graminis	36.17	4.00e-15	75.50
IUUC-Gga-040835	Gallus gallus	92.33	0.00e+00	2276.00
IUUC-Gac-041948	Gasterosteus aculeatus	72.24	0.00e+00	1820.00
IUUC-Hsa-045699	Homo sapiens	89.54	0.00e+00	2246.00
IUUC-Hvu-047530	Hordeum vulgare	32.94	2.00e-14	74.30
IUUC-Itr-048773	Ictidomys tridecemlineatus	86.33	0.00e+00	2166.00
IUUC-Lch-050502	Latimeria chalumnae	77.90	0.00e+00	1628.00
IUUC-Lpe-051250	Leersia perrieri	41.67	3.00e-14	74.30
IUUC-Loc-052613	Lepisosteus oculatus	81.35	0.00e+00	1982.00
IUUC-Laf-053608	Loxodonta africana	87.23	0.00e+00	2210.00
IUUC-Mcc-055720	Macaca mulatta	89.74	0.00e+00	2222.00
IUUC-Meu-056445	Macropus eugenii	82.03	0.00e+00	1652.00
IUUC-Mla-059128	Melampsora laricipopulina	29.48	2.00e-41	165.00
IUUC-Mvi-060268	Microbotryum violaceum	29.92	7.00e-44	173.00
IUUC-Mmr-061258	Microcebus murinus	88.99	0.00e+00	2198.00
IUUC-Mdo-062019	Monodelphis domestica	87.97	0.00e+00	2144.00
IUUC-Mmu-063885	Mus musculus	88.43	0.00e+00	2244.00
IUUC-Opr-070441	Ochotona princeps	83.56	0.00e+00	1934.00
IUUC-Ont-071752	Oreochromis niloticus	72.60	0.00e+00	1811.00
IUUC-Oan-073390	Ornithorhynchus anatinus	85.43	0.00e+00	2113.00
IUUC-Ocu-073753	Oryctolagus cuniculus	86.99	0.00e+00	2774.00
IUUC-Obr-076390	Oryza brachyantha	41.89	7.00e-09	54.70
IUUC-Ogu-078849	Oryza glumaepatula	42.86	1.00e-14	75.90
IUUC-Olo-080259	Oryza longistaminata	42.86	6.00e-15	76.60
IUUC-Ome-081199	Oryza meridionalis	42.86	8.00e-15	76.30
IUUC-Oni-082167	Oryza nivara	42.86	2.00e-14	75.10
IUUC-Oru-084541	Oryza rufipogon	42.86	2.00e-14	75.10
IUUC-Olu-087698	Ostreococcus lucimarinus	29.17	6.00e-16	79.30
IUUC-Oga-088602	Otolemur garnettii	88.86	0.00e+00	2228.00
IUUC-Oar-090195	Ovis aries	89.57	0.00e+00	2233.00
IUUC-Ptr-091363	Pan troglodytes	89.62	0.00e+00	2248.00
IUUC-Pan-092385	Papio anubis	89.03	0.00e+00	2208.00
IUUC-Ppa-095464	Physcomitrella patens	28.71	1.00e-12	69.30
IUUC-Pfo-097486	Poecilia formosa	73.48	0.00e+00	1868.00
IUUC-Pab-098281	Pongo abelii	77.83	0.00e+00	1840.00
IUUC-Pca-100270	Procavia capensis	71.69	0.00e+00	1246.00
IUUC-Pva-102335	Pteropus vampyrus	84.95	0.00e+00	2150.00
IUUC-Pgr-103473	Puccinia graminis	28.69	1.00e-37	153.00
IUUC-Ptt-103973	Puccinia triticina	24.80	2.00e-27	119.00
IUUC-Rno-106122	Rattus norvegicus	88.09	0.00e+00	2246.00
IUUC-Sha-106851	Sarcophilus harrisii	86.99	0.00e+00	2154.00
IUUC-Spo-108101	Schizosaccharomyces pombe	45.00	6.00e-17	82.80
IUUC-Ssl-108415	Sclerotinia sclerotiorum	46.03	4.00e-14	72.40
IUUC-Sit-110414	Setaria italica	41.67	1.00e-14	75.50
IUUC-Sbi-114170	Sorghum bicolor	39.78	6.00e-15	76.60
IUUC-Tgu-117028	Taeniopygia guttata	97.61	0.00e+00	2468.00
IUUC-Tru-117789	Takifugu rubripes	74.55	0.00e+00	1850.00
IUUC-Tsy-119039	Tarsius syrichta	90.78	0.00e+00	1358.00
IUUC-Tni-119952	Tetraodon nigroviridis	73.72	0.00e+00	1747.00
IUUC-Tvi-122297	Trichoderma virens	42.42	5.00e-14	71.60
IUUC-Tae-123242	Triticum aestivum	41.67	2.00e-14	74.70
IUUC-Tur-126623	Triticum urartu	40.00	2.00e-14	74.70
IUUC-Tbe-127754	Tupaia belangeri	76.45	0.00e+00	1504.00
IUUC-Ttr-129178	Tursiops truncatus	89.54	0.00e+00	2217.00
IUUC-Uma-129456	Ustilago maydis	31.01	9.00e-32	133.00
IUUC-Vpa-130687	Vicugna pacos	84.03	0.00e+00	1077.00
IUUC-Xtr-132905	Xenopus tropicalis	86.58	0.00e+00	2153.00
IUUC-Xma-134144	Xiphophorus maculatus	75.35	0.00e+00	1864.00
IUUC-Yli-134511	Yarrowia lipolytica	31.21	2.00e-09	57.80

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence