iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-007702

UUCD1 version

UUC-ArT-01643

Ensembl Protein ID

AT1G45050.1

UniProt Accession

P42743; O48952; Q67XR1; Q9MAK4; UBC15_ARATH

Genbank Protein ID

CAA48378.1; AAC39324.1; AAY44855.1; AAF69157.1; AEE32077.1; ABG48461.1; BAD44520.1

Protein Name

Ubiquitin-conjugating enzyme 15; E2 ubiquitin-conjugating enzyme 15; PM42; Ubiquitin carrier protein; Ubiquitin-conjugating enzyme E2-18 kDa 15; Ubiquitin-protein ligase

Genbank Nucleotide ID

X68306; AF028338; DQ027029; AC007915; CP002684; BT026105; AK176757

Gene Name

UBC15; UBC2-1; At1g45050; F27F5.13

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT1G45050	AT1G45050.2	AT1G45050.2
AT1G45050	AT1G45050.1	AT1G45050.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
HINT
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.10e-35	123.3	19	145

Active Site

Position(s)	Description	Evidence
99	Glycyl thioester intermediate	{ECO:0000255\|PROSITE-ProRule:PRU00388, ECO:0000255\|PROSITE-ProRule:PRU10133}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltk.ifhPnvyenGkvClsilkeeekWspals 97
           Rl+kel+e++ +pp+g++ k++d+  l++w + ++G ++t Y++++++l++efpe+YP+++P+v f+++   hP++y+nG++Cl+il   + Wspa++
   Q: 19   RLQKELSEWQLNPPTGFRHKVTDN--LQKWTIDVTGAPGTLYANETYQLQVEFPEHYPMEAPQVVFVSPaPSHPHIYSNGHICLDILY--DSWSPAMT 112
           9****************9998887..******************************************989****************9..******** PP
   S: 98   vesvllsiqsll.aepnpesplneeaaellkkn 129
           v+sv++si s+l ++p  + p++++ + + +kn
   Q: 113  VNSVCISILSMLsSSPAKQRPADNDRYVKNCKN 145
           ************667*******99988555444 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.

Protein Sequence
(Fasta)

MTSSSAPSRK ALSKIACNRL QKELSEWQLN PPTGFRHKVT DNLQKWTIDV TGAPGTLYAN 60
ETYQLQVEFP EHYPMEAPQV VFVSPAPSHP HIYSNGHICL DILYDSWSPA MTVNSVCISI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAAAATTAAG AATAGTAAAA AGCTCTTCAT TTGCATAAGA AAAAAACAAA AAACAGAAAA 60
CAAAAAAAAA AGACAAAGTA AGGAGGCCAG ACAGCAGACC CGTCTCTCTC CGTCTCCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ath:AT1G45050

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008034	Aspergillus clavatus	38.41	4.00e-21	92.80
IUUC-Afu-008827	Aspergillus fumigatus	39.24	1.00e-22	98.20
IUUC-Ang-009545	Aspergillus niger	39.74	1.00e-21	95.10
IUUC-Aor-009924	Aspergillus oryzae	39.01	2.00e-20	90.50
IUUC-Ate-010478	Aspergillus terreus	33.71	6.00e-18	82.80
IUUC-Bgr-012004	Blumeria graminis	42.86	1.00e-24	104.00
IUUC-Bol-016083	Brassica oleracea	95.39	2.00e-81	293.00
IUUC-Cel-018273	Caenorhabditis elegans	50.65	9.00e-37	145.00
IUUC-Cgl-026554	Colletotrichum gloeosporioides	41.94	9.00e-27	111.00
IUUC-Cme-027157	Cyanidioschyzon merolae	55.00	1.00e-42	164.00
IUUC-Dse-031193	Dothistroma septosporum	37.34	2.00e-21	94.00
IUUC-Fal-037512	Ficedula albicollis	53.28	6.00e-33	132.00
IUUC-Fso-038237	Fusarium solani	38.82	1.00e-18	85.10
IUUC-Ggr-040091	Gaeumannomyces graminis	39.10	4.00e-25	106.00
IUUC-Mpo-057368	Magnaporthe poae	38.46	9.00e-25	105.00
IUUC-Mla-059112	Melampsora laricipopulina	46.58	5.00e-26	109.00
IUUC-Nfi-068242	Neosartorya fischeri	37.28	8.00e-22	95.90
IUUC-Oba-075077	Oryza barthii	86.96	4.00e-77	279.00
IUUC-Obr-076142	Oryza brachyantha	84.47	6.00e-77	278.00
IUUC-Ogl-077944	Oryza glaberrima	87.58	2.00e-77	280.00
IUUC-Ogu-078453	Oryza glumaepatula	86.96	4.00e-77	279.00
IUUC-Olo-080356	Oryza longistaminata	87.58	2.00e-77	280.00
IUUC-Ome-081601	Oryza meridionalis	87.58	2.00e-77	280.00
IUUC-Oni-082554	Oryza nivara	86.96	4.00e-77	279.00
IUUC-Opu-083614	Oryza punctata	86.96	3.00e-77	280.00
IUUC-Oru-085028	Oryza rufipogon	87.58	2.00e-77	280.00
IUUC-Osa-085386	Oryza sativa	87.58	2.00e-77	280.00
IUUC-Ola-086845	Oryzias latipes	49.48	5.00e-24	101.00
IUUC-Pva-102207	Pteropus vampyrus	55.26	3.00e-31	125.00
IUUC-Pgr-103668	Puccinia graminis	46.75	6.00e-33	132.00
IUUC-Sit-110080	Setaria italica	87.58	2.00e-77	280.00
IUUC-Stu-112148	Solanum tuberosum	88.20	2.00e-76	276.00
IUUC-Sbi-114650	Sorghum bicolor	88.20	7.00e-78	281.00
IUUC-Tvi-122565	Trichoderma virens	39.71	2.00e-20	90.90
IUUC-Ttr-128279	Tursiops truncatus	48.61	2.00e-32	130.00
IUUC-Vpa-130053	Vicugna pacos	51.16	2.00e-32	130.00
IUUC-Zma-135814	Zea mays	86.96	7.00e-77	278.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence