iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ata-000060

Ensembl Protein ID

EMT20382

UniProt Accession

R7WCG4; R7WCG4_AEGTA

Genbank Protein ID

EMT20382.1

Protein Name

E3 ubiquitin-protein ligase UPL3

Genbank Nucleotide ID

KD527029

Gene Name

F775_19700

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
F775_19700	EMT20382	EMT20382

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	9.30e-101	338.3	1224	1633

Active Site

Position(s)	Description	Evidence
1601	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysen.dketlqpnpdsglknp.................................... 65
           +++++leve+ gE g++l G+t+ef++ll +elq++ lgl++ s+  d ++++++++  ++                                      
   Q: 1224 SQRAVLEVEYFGEVGTGL-GPTLEFYTLLGHELQSARLGLWRSSSPyDYSEMEIDKNGVIHVDsdddspapqelnssedarnlvqaplglfprpwpsnv 1321
           67899*************.**********************98888788899******9988899********************************** PP
   S: 66   .........ehlklFeflGrllgkalqdgrlldlplsksfyklllgkklsledleevdpelykslkeikenaes...........dieelgldltfsvs 144
                    ++ ++F+++Gr+++k+lqdgrlldlpls++fykl+lg++l+l d+ ++d+el k+l+e++ ++e+           ++e ++l ++  + 
   Q: 1322 dtsegsrflKVVEYFRLVGRVVAKVLQDGRLLDLPLSTAFYKLILGQELDLFDIISFDAELGKTLQELRVLVERkrflestcgkdQLEVADLRFRGAPI 1420
           *********************************************************************999444555556665566666677777777 PP
   S: 145  eei.....lgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykg 237
           e++     l+   ++ Lk+g +n+ V++ N+eeYv+lvv++++k+gi +qveafr+Gf++v+++++l++F+++el++licG+ e +++e+l +++k+++
   Q: 1421 EDLcldftLPGFPDYILKEGEQNTIVNIHNLEEYVSLVVDATVKSGIMKQVEAFRSGFSQVFDISSLQIFSPQELDYLICGRqEIWEAESLVDNIKFDH 1519
           77777777999***********************************************************************8889************* PP
   S: 238  gytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirk...............dasddrlPssnTCfnyLkLPeYsskeilke 321
           g+t++spai++++e+++ef+ +++ af+qFvTg srlP gG+a+l+p+l+++rk               da+dd+lPs++TC+nyLkLP+Ys+ke++++
   Q: 1520 GFTAKSPAIINLLEIMSEFTPDQQHAFCQFVTGASRLPTGGLAALSPKLTIVRKhpssgvstlntsgvtDAADDDLPSVMTCANYLKLPPYSTKEVMRK 1618
           *************************************************************************************************** PP
   S: 322  kLlyAieet.kgFel 335
           kLlyAi e+  +F+l
   Q: 1619 KLLYAILEGrGSFDL 1633
           *********999987 PP

Organism

Aegilops tauschii

Protein Sequence
(Fasta)

MQLCEMLSIG TEDSLAAFPI DAFVPLLVGL LREEDGPGAS PEVMLLAARA LANLVDVLPS 60
ACSSVVHYGA IPCFCARLLT IEYMDLAEQS LQALRKISLE HPTACLRAGA LMAVLSYLDF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGCTCT GTGAGATGCT CTCCATCGGC ACCGAGGACT CGCTCGCCGC CTTCCCCATC 60
GACGCCTTCG TGCCGCTCCT CGTCGGCCTG CTCCGCGAGG AGGACGGCCC CGGCGCCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0436--Ligase
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

ats:F775_19700

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Afl-008736	Aspergillus flavus	35.25	4.00e-109	389.00
IUUC-Aor-009941	Aspergillus oryzae	35.25	7.00e-109	388.00
IUUC-Bgr-012265	Blumeria graminis	37.23	4.00e-102	366.00
IUUC-Bci-013890	Botrytis cinerea	38.50	1.00e-100	361.00
IUUC-Bdi-014961	Brachypodium distachyon	85.02	0.00e+00	2472.00
IUUC-Cin-025482	Ciona intestinalis	37.50	7.00e-97	347.00
IUUC-Csv-026121	Ciona savignyi	33.47	2.00e-102	367.00
IUUC-Fso-038320	Fusarium solani	39.66	1.00e-110	394.00
IUUC-Hvu-047586	Hordeum vulgare	97.05	0.00e+00	2200.00
IUUC-Kpa-049098	Komagataella pastoris	38.16	2.00e-87	317.00
IUUC-Lpe-051017	Leersia perrieri	77.11	0.00e+00	2274.00
IUUC-Obr-076915	Oryza brachyantha	78.99	0.00e+00	2326.00
IUUC-Ogl-077055	Oryza glaberrima	79.56	0.00e+00	2257.00
IUUC-Ogu-078685	Oryza glumaepatula	76.13	0.00e+00	2135.00
IUUC-Oin-079256	Oryza indica	77.33	0.00e+00	2265.00
IUUC-Olo-080343	Oryza longistaminata	77.39	0.00e+00	2263.00
IUUC-Ome-081422	Oryza meridionalis	77.45	0.00e+00	2270.00
IUUC-Opu-083792	Oryza punctata	76.22	0.00e+00	2192.00
IUUC-Osa-085972	Oryza sativa	84.25	0.00e+00	1179.00
IUUC-Ppa-095264	Physcomitrella patens	52.45	0.00e+00	721.00
IUUC-Pte-104346	Pyrenophora teres	38.92	2.00e-105	377.00
IUUC-Sit-110717	Setaria italica	79.00	0.00e+00	2318.00
IUUC-Tae-123120	Triticum aestivum	94.62	0.00e+00	2836.00
IUUC-Vda-129725	Verticillium dahliae	40.15	5.00e-108	386.00
IUUC-Zma-135657	Zea mays	74.44	0.00e+00	2255.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence