iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
fgenesh2_kg.3__2290__AT3G20630.1	fgenesh2_kg.3__2290__AT3G20630.1	fgenesh2_kg.3__2290__AT3G20630.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.50e-52	179.6	308	795
UBD/Alpha-Helix/UBA	3.80e-17	62.5	614	654

Active Site

Position(s)	Description	Evidence
317	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
758	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkekln.eenpkepkgellkslqklfeel..............w. 61
           tGl NlgN+CY+ +++Q  ++ +++ + ++++++ k++ e +p +p+ +l ++l+kl + l              + 
   Q: 308  TGLVNLGNSCYLAATMQIVFSNHSFISRYFSHQSLKMAfEMAPADPTLDLNMQLTKLGHGLlsgkysipatqkdaTt 384
           7************************99888856555551456789999*************7777777766655514 PP
   S: 62   .kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkk 137
            + +++ + pr++++++++ + efs+++qqDa Ef+ +l+ ++e++                            ++ 
   Q: 385  gDARQEGIPPRMFKNVIAASHAEFSSMRQQDALEFFLHLVGKVERAS---------------------------NTT 434
           677778***************************************99...........................445 PP
   S: 138  nkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke............................. 185
            +   s+ F++ ++++i c++ +  ++++e+ + lsl++p +e t+k                              
   Q: 435  PDLDPSRSFKFGIEEKILCPSGKVGYNKRED-CILSLNIPLHEATNKDeleafnkqkagkgleendirssdeivrpr 510
           66668999************99888855543.5555555555555444569************************** PP
   S: 186  .slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
             l+ cL++f++ e +++   yy++  k++++a k+++l+++P++L+lh+ +f + e++++++k++ ++++p+ +d+
   Q: 511  vPLEACLANFASSEAIDD---YYSSALKGRTTAIKTTGLTSFPDYLVLHMRKF-VMEAGWVPKKLDVYIDVPDVIDI 583
           ****************97...********************************.77889****************** PP
   S: 262  spfcts....................................................................... 267
           s++ ++                                                                       
   Q: 584  SHMRSKglqpgeellpdgvpeeviesaqpvaneeivaqlvsmgfsqlhcqkaaintsnagveeamnwllshmddpdi 660
           *9999999999999999999988888888888888888888888888887777777777777777777777777777 PP
   S: 268  ..............................peekqke........................................ 274
                                         +                                              
   Q: 661  dapishqtsdvdqssldallsfgfaedvarK-----Alkasggdiekatdwifnnpnasvsdmdvsssnsaqtpaqs 732
           7766666665555555555555555555550.....05555555555555556666666666666667777788889 PP
   S: 275  .....kkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
                  kY+L+++v+H+G s+++GHYva++ + +g+W+ f+D+kV  +  ++  +   + +Yv+f++r
   Q: 733  glpdgGGKYKLFGIVSHMGtSVHCGHYVAHILK-EGRWVIFNDDKVGIS--TDPPK---DMGYVYFFQR 795
           999999***************************.9***********999..78889...99*****997 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           ++e++++qlv+MGF++ ++++a  ++ n  +e+A+++Ll++
   Q: 614  ANEEIVAQLVSMGFSQLHCQKAAINTsNAGVEEAMNWLLSH 654
           589************************************97 PP

Organism

Arabidopsis lyrata

Protein Sequence
(Fasta)

MELLRSNLSR VQIPEPTHRI YKHECCISFD TPRSEGGLFV DMNSFLAFGK DYVSWNYEKT 60
GNPVYLHIKQ TTKSIPEDRP LKKPTLLAIG VDGGFDNNEP EYEESYSIVI LPDFVSLPFP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAACCCTAT GGAGCTCCTC CGATCCAACT TGTCTAGGGT TCAGATCCCT GAACCTACTC 60
ATCGCATCTA CAAGCATGAG TGTTGCATCT CCTTCGATAC TCCGGTAAAA CCTCTCTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0009793--P:embryo development ending in seed dormancy
GO:0016579--P:protein deubiquitination
GO:0048767--P:root hair elongation
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

aly:ARALYDRAFT_479589

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	64.59	0.00e+00	1011.00
IUUC-Aml-002104	Ailuropoda melanoleuca	46.92	0.00e+00	736.00
IUUC-Atr-002580	Amborella trichopoda	66.28	0.00e+00	1148.00
IUUC-Apl-003774	Anas platyrhynchos	47.45	0.00e+00	732.00
IUUC-Aca-005368	Anolis carolinensis	48.26	0.00e+00	774.00
IUUC-Ath-006974	Arabidopsis thaliana	97.74	0.00e+00	1568.00
IUUC-Ago-007890	Ashbya gossypii	27.73	7.00e-71	261.00
IUUC-Acl-008057	Aspergillus clavatus	34.05	2.00e-119	422.00
IUUC-Afl-008547	Aspergillus flavus	36.89	1.00e-113	403.00
IUUC-Afu-008805	Aspergillus fumigatus	33.90	9.00e-110	390.00
IUUC-Ani-009441	Aspergillus nidulans	34.64	4.00e-96	345.00
IUUC-Ang-009720	Aspergillus niger	34.63	1.00e-112	400.00
IUUC-Aor-010111	Aspergillus oryzae	34.89	2.00e-123	435.00
IUUC-Ate-010531	Aspergillus terreus	32.17	1.00e-98	353.00
IUUC-Ame-011470	Astyanax mexicanus	42.33	0.00e+00	662.00
IUUC-Bgr-012183	Blumeria graminis	32.52	2.00e-110	392.00
IUUC-Bta-013179	Bos taurus	47.13	0.00e+00	741.00
IUUC-Bci-013858	Botrytis cinerea	34.70	1.00e-125	443.00
IUUC-Bdi-014904	Brachypodium distachyon	69.49	0.00e+00	1116.00
IUUC-Bol-015536	Brassica oleracea	90.36	0.00e+00	1472.00
IUUC-Bra-017939	Brassica rapa	90.97	0.00e+00	1481.00
IUUC-Cel-018625	Caenorhabditis elegans	34.61	8.00e-121	427.00
IUUC-Cja-019063	Callithrix jacchus	46.80	0.00e+00	731.00
IUUC-Cfa-020976	Canis familiaris	48.56	0.00e+00	754.00
IUUC-Cpo-022265	Cavia porcellus	48.33	0.00e+00	756.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	38.82	4.00e-112	397.00
IUUC-Csa-024078	Chlorocebus sabaeus	42.89	0.00e+00	659.00
IUUC-Cho-024702	Choloepus hoffmanni	41.55	5.00e-115	407.00
IUUC-Cin-025411	Ciona intestinalis	42.65	2.00e-177	615.00
IUUC-Csv-026347	Ciona savignyi	40.39	1.00e-171	596.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	34.47	7.00e-110	390.00
IUUC-Cne-026831	Cryptococcus neoformans	35.80	4.00e-124	438.00
IUUC-Cme-027335	Cyanidioschyzon merolae	35.40	4.00e-38	152.00
IUUC-Dre-027651	Danio rerio	42.76	0.00e+00	692.00
IUUC-Dno-029034	Dasypus novemcinctus	47.26	0.00e+00	742.00
IUUC-Dor-030130	Dipodomys ordii	42.16	3.00e-95	342.00
IUUC-Dse-031467	Dothistroma septosporum	35.45	2.00e-118	419.00
IUUC-Dme-032075	Drosophila melanogaster	44.22	0.00e+00	651.00
IUUC-Ete-032865	Echinops telfairi	43.81	0.00e+00	658.00
IUUC-Eca-034059	Equus caballus	47.16	0.00e+00	741.00
IUUC-Eeu-035304	Erinaceus europaeus	45.02	0.00e+00	667.00
IUUC-Fca-035515	Felis catus	47.14	0.00e+00	743.00
IUUC-Fal-037271	Ficedula albicollis	48.99	0.00e+00	725.00
IUUC-Fox-037745	Fusarium oxysporum	36.49	5.00e-128	451.00
IUUC-Fso-038158	Fusarium solani	36.06	1.00e-121	430.00
IUUC-Gmo-039071	Gadus morhua	44.50	0.00e+00	657.00
IUUC-Ggr-040098	Gaeumannomyces graminis	35.09	1.00e-118	420.00
IUUC-Gga-040635	Gallus gallus	47.26	0.00e+00	765.00
IUUC-Gac-042528	Gasterosteus aculeatus	43.93	0.00e+00	667.00
IUUC-Gma-043614	Glycine max	76.49	0.00e+00	1211.00
IUUC-Ggo-044602	Gorilla gorilla	47.02	0.00e+00	743.00
IUUC-Hsa-045959	Homo sapiens	47.02	0.00e+00	743.00
IUUC-Hvu-047563	Hordeum vulgare	67.81	0.00e+00	872.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	47.14	0.00e+00	742.00
IUUC-Kpa-049156	Komagataella pastoris	32.45	7.00e-107	380.00
IUUC-Lch-049648	Latimeria chalumnae	48.19	0.00e+00	754.00
IUUC-Lpe-051523	Leersia perrieri	67.16	0.00e+00	1094.00
IUUC-Loc-052072	Lepisosteus oculatus	43.29	0.00e+00	674.00
IUUC-Lma-053216	Leptosphaeria maculans	34.53	7.00e-107	382.00
IUUC-Laf-054327	Loxodonta africana	47.26	0.00e+00	744.00
IUUC-Mcc-055443	Macaca mulatta	47.02	0.00e+00	743.00
IUUC-Meu-056298	Macropus eugenii	50.09	2.00e-153	536.00
IUUC-Mor-057106	Magnaporthe oryzae	35.38	1.00e-120	426.00
IUUC-Mpo-057589	Magnaporthe poae	35.18	4.00e-117	415.00
IUUC-Mtr-058680	Medicago truncatula	75.37	0.00e+00	1234.00
IUUC-Mla-058903	Melampsora laricipopulina	33.82	9.00e-111	394.00
IUUC-Mga-059669	Meleagris gallopavo	47.35	0.00e+00	723.00
IUUC-Mvi-060476	Microbotryum violaceum	34.23	2.00e-106	379.00
IUUC-Mmr-060575	Microcebus murinus	47.02	0.00e+00	741.00
IUUC-Mdo-062183	Monodelphis domestica	47.74	0.00e+00	745.00
IUUC-Mmu-063592	Mus musculus	47.14	0.00e+00	745.00
IUUC-Mac-065446	Musa acuminata	65.47	0.00e+00	1112.00
IUUC-Mpu-066082	Mustela putorius furo	48.44	0.00e+00	751.00
IUUC-Mlu-067345	Myotis lucifugus	46.90	0.00e+00	734.00
IUUC-Nfi-068558	Neosartorya fischeri	34.98	5.00e-121	427.00
IUUC-Ncr-068960	Neurospora crassa	33.13	8.00e-110	390.00
IUUC-Nle-070173	Nomascus leucogenys	48.44	0.00e+00	754.00
IUUC-Opr-070556	Ochotona princeps	47.48	0.00e+00	753.00
IUUC-Ont-071502	Oreochromis niloticus	45.01	0.00e+00	675.00
IUUC-Oan-072959	Ornithorhynchus anatinus	54.94	7.00e-71	259.00
IUUC-Ocu-074861	Oryctolagus cuniculus	48.67	0.00e+00	763.00
IUUC-Oba-075109	Oryza barthii	67.16	0.00e+00	1097.00
IUUC-Obr-076292	Oryza brachyantha	67.25	0.00e+00	1087.00
IUUC-Ogl-077065	Oryza glaberrima	68.66	0.00e+00	1141.00
IUUC-Ogu-078776	Oryza glumaepatula	67.04	0.00e+00	1115.00
IUUC-Oin-080048	Oryza indica	68.41	0.00e+00	1134.00
IUUC-Olo-080711	Oryza longistaminata	65.51	0.00e+00	1019.00
IUUC-Ome-081506	Oryza meridionalis	66.84	0.00e+00	1029.00
IUUC-Oni-082320	Oryza nivara	65.30	0.00e+00	1088.00
IUUC-Opu-083801	Oryza punctata	67.53	0.00e+00	1085.00
IUUC-Oru-085139	Oryza rufipogon	65.30	0.00e+00	1088.00
IUUC-Osa-085713	Oryza sativa	68.78	0.00e+00	1145.00
IUUC-Ola-086951	Oryzias latipes	42.84	0.00e+00	639.00
IUUC-Olu-087822	Ostreococcus lucimarinus	39.20	2.00e-161	561.00
IUUC-Oga-088625	Otolemur garnettii	47.08	0.00e+00	739.00
IUUC-Oar-089995	Ovis aries	46.72	0.00e+00	733.00
IUUC-Ptr-090640	Pan troglodytes	46.32	0.00e+00	744.00
IUUC-Pan-091974	Papio anubis	46.92	0.00e+00	736.00
IUUC-Psi-093957	Pelodiscus sinensis	47.26	0.00e+00	772.00
IUUC-Pma-094242	Petromyzon marinus	48.45	1.00e-104	372.00
IUUC-Pno-094835	Phaeosphaeria nodorum	36.07	1.00e-104	373.00
IUUC-Ppa-095901	Physcomitrella patens	64.76	0.00e+00	1080.00
IUUC-Pfo-097148	Poecilia formosa	44.66	0.00e+00	672.00
IUUC-Pab-098068	Pongo abelii	42.54	2.00e-178	619.00
IUUC-Pop-098855	Populus trichocarpa	77.82	0.00e+00	1233.00
IUUC-Pca-100738	Procavia capensis	44.72	8.00e-143	500.00
IUUC-Ppe-101315	Prunus persica	78.39	0.00e+00	1248.00
IUUC-Pva-102154	Pteropus vampyrus	46.67	0.00e+00	734.00
IUUC-Pgr-103343	Puccinia graminis	33.82	8.00e-98	350.00
IUUC-Ptt-103928	Puccinia triticina	28.03	3.00e-88	318.00
IUUC-Pte-104306	Pyrenophora teres	33.37	5.00e-99	355.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	34.41	1.00e-106	380.00
IUUC-Rno-105801	Rattus norvegicus	47.26	0.00e+00	745.00
IUUC-Sce-106304	Saccharomyces cerevisiae	31.34	9.00e-70	257.00
IUUC-Sha-107635	Sarcophilus harrisii	48.62	0.00e+00	749.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	33.42	3.00e-97	348.00
IUUC-Spo-108144	Schizosaccharomyces pombe	34.31	6.00e-112	397.00
IUUC-Smo-108848	Selaginella moellendorffii	62.31	0.00e+00	973.00
IUUC-Sit-110728	Setaria italica	70.57	0.00e+00	1173.00
IUUC-Sly-111523	Solanum lycopersicum	71.82	0.00e+00	1215.00
IUUC-Sar-113733	Sorex araneus	46.72	1.00e-95	343.00
IUUC-Sbi-114419	Sorghum bicolor	70.24	0.00e+00	1154.00
IUUC-Sre-115225	Sporisorium reilianum	32.57	1.00e-107	383.00
IUUC-Ssc-115686	Sus scrofa	46.91	0.00e+00	738.00
IUUC-Tgu-117346	Taeniopygia guttata	47.32	0.00e+00	749.00
IUUC-Tru-118350	Takifugu rubripes	43.97	0.00e+00	667.00
IUUC-Tsy-119278	Tarsius syrichta	39.53	6.00e-160	557.00
IUUC-Tni-120658	Tetraodon nigroviridis	43.99	0.00e+00	651.00
IUUC-Tca-121585	Theobroma cacao	78.54	0.00e+00	1262.00
IUUC-Tre-122043	Trichoderma reesei	35.49	2.00e-115	409.00
IUUC-Tvi-122303	Trichoderma virens	36.85	1.00e-122	433.00
IUUC-Tae-123798	Triticum aestivum	68.49	0.00e+00	1130.00
IUUC-Tur-126732	Triticum urartu	64.51	0.00e+00	1058.00
IUUC-Tme-126909	Tuber melanosporum	33.62	1.00e-102	367.00
IUUC-Tbe-127261	Tupaia belangeri	40.07	5.00e-119	421.00
IUUC-Ttr-128295	Tursiops truncatus	37.99	6.00e-163	567.00
IUUC-Uma-129599	Ustilago maydis	33.07	5.00e-115	408.00
IUUC-Vda-129688	Verticillium dahliae	34.70	4.00e-116	411.00
IUUC-Vpa-130170	Vicugna pacos	37.13	4.00e-143	501.00
IUUC-Vvi-131116	Vitis vinifera	76.24	0.00e+00	1225.00
IUUC-Xtr-131953	Xenopus tropicalis	46.85	0.00e+00	718.00
IUUC-Xma-133837	Xiphophorus maculatus	44.66	0.00e+00	672.00
IUUC-Yli-134510	Yarrowia lipolytica	34.24	7.00e-109	387.00
IUUC-Zma-135786	Zea mays	68.37	0.00e+00	1116.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence