iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ogl-077065

UUCD1 version

UUC-OrG-02688

Ensembl Protein ID

ORGLA01G0046200.1

UniProt Accession

I1NKS2; I1NKS2_ORYGL

Protein Name

Ubiquitinyl hydrolase 1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ORGLA01G0046200	ORGLA01G0046200.1	ORGLA01G0046200.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.70e-55	188.1	311	793
UBD/Alpha-Helix/UBA	8.10e-17	61.4	671	709

Active Site

Position(s)	Description	Evidence
320	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
756	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw........kskkkavsprellkalkkeaee 83
           tGl NlgN+CYm Sv+Q++++++++ + ++e +  ++  + +p +p+ +l ++++kl + ++        ++ ++ + pr+++++++++++e
   Q: 311  TGLVNLGNSCYMASVMQVMFSTHPFISRYFEkQSLKAAFAIAPADPTLDLNMQMTKLAHGMLsgkcsvpnQEGQEGIHPRMFKTVIAAKHPE 402
           7************************99888833344444567899****************76666667788888***************** PP
   S: 84   fsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslp 175
           fs+++qqDa +f+ +l+dq++++                           + +++ ++  + F++ ++++++c++  +vs  + + + lsl+
   Q: 403  FSSMRQQDALDFFLHLIDQVDQAN--------------------------TGNHELNPF-TGFKFIIEERLQCPSG-KVSYNKRSDYILSLN 466
           *********************988..........................455555555.67***********985.566566667888888 PP
   S: 176  vpgkeetkke.............................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfs 238
           +p +e t+ke                              l+ cL+sf+ +ee+ +   +y++  ++k++a k+ ++k++P++L+l++ +f 
   Q: 467  IPLHEATNKEqleafhekkaamdldgkevsneeivrprvPLEACLASFSGAEEVPE---FYSTALNSKTTAIKTAGFKTFPDYLVLQMRKF- 554
           888887777788******************************************96...********************************. PP
   S: 239  fseeqksrekinkkvefpleLdlspfcts............................................................... 267
           + e++++++k++ +v++p+ +d+s++ ++                                                               
   Q: 555  VMEAGWVPKKLDVYVDVPDIIDISHMRSKgiqpgeellpegasgdnkaepvhpvasedivsqlasmgfnylhcqkaaistsntgveeamnwl 646
           77889*******************99999999999999999998888888888888888888888888888888888887777777777777 PP
   S: 268  .....................peekqke................................................................ 274
                                +     +                                                                
   Q: 647  lshmddpdindpiskdsqaaeQ-----Tvdetsvqtlvsfgfqedvarkalaasggnieratdwifshpeafssvptdsstsnmedddahip 733
           7777777777776665555550.....05555555666666666666666666666666667777777777777777777778888999999 PP
   S: 275  ..kkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
             + +Y+L+a v+H+G s+++GHYva+v + +g+W+ f+DskV ++   +  +   + +Y++f++r
   Q: 734  dgSGRYKLMAFVSHMGtSTHCGHYVAHVLK-DGRWVIFNDSKVAAS--VDLPK---DMGYLYFFQR 793
           99****************************.9***********999..68888...999**99997 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraannnleaAveyLldg 41
           de  ++ lv+ GF ++ a++aL+a+++n+e+A+++++++
   Q: 671  DETSVQTLVSFGFQEDVARKALAASGGNIERATDWIFSH 709
           7999*********************************97 PP

Organism

Oryza glaberrima

Protein Sequence
(Fasta)

MDLLRSHLHK VRIPEPGSRI HKDECCVSFD TPRSEGGLYV DMTSFLGFGR EHVAWNYEKS 60
GNPVYLHIVQ RRKPEPDDEA DRPLKKPTLL AIGVEGGFTD QEPEYDEAFE IVILPEFTSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATCTCC TCCGCTCGCA CCTCCACAAG GTCCGCATCC CGGAGCCCGG CAGCCGCATC 60
CACAAGGACG AGTGCTGCGT CTCCTTCGAC ACCCCGGTAA ACCAACCACC CACCCACCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	82.81	0.00e+00	1293.00
IUUC-Aml-002104	Ailuropoda melanoleuca	47.66	0.00e+00	749.00
IUUC-Atr-002580	Amborella trichopoda	73.82	7.00e-178	616.00
IUUC-Apl-003774	Anas platyrhynchos	47.99	0.00e+00	733.00
IUUC-Aca-005368	Anolis carolinensis	49.64	0.00e+00	778.00
IUUC-Aly-005727	Arabidopsis lyrata	68.66	0.00e+00	1137.00
IUUC-Ath-006974	Arabidopsis thaliana	69.03	0.00e+00	1143.00
IUUC-Ago-007890	Ashbya gossypii	28.30	4.00e-74	271.00
IUUC-Acl-008057	Aspergillus clavatus	36.24	3.00e-123	434.00
IUUC-Afl-008547	Aspergillus flavus	35.93	5.00e-110	390.00
IUUC-Afu-008805	Aspergillus fumigatus	34.59	2.00e-107	382.00
IUUC-Ani-009441	Aspergillus nidulans	38.23	3.00e-95	342.00
IUUC-Ang-009720	Aspergillus niger	35.09	1.00e-113	402.00
IUUC-Aor-010111	Aspergillus oryzae	34.71	2.00e-119	422.00
IUUC-Ate-010531	Aspergillus terreus	33.29	1.00e-100	360.00
IUUC-Ame-011470	Astyanax mexicanus	42.39	0.00e+00	665.00
IUUC-Bgr-012183	Blumeria graminis	32.11	5.00e-105	374.00
IUUC-Bta-013179	Bos taurus	48.00	0.00e+00	755.00
IUUC-Bci-013858	Botrytis cinerea	33.46	8.00e-113	400.00
IUUC-Bdi-014904	Brachypodium distachyon	90.05	0.00e+00	1442.00
IUUC-Bol-015536	Brassica oleracea	69.44	0.00e+00	1138.00
IUUC-Bra-017939	Brassica rapa	69.36	0.00e+00	1140.00
IUUC-Cel-018625	Caenorhabditis elegans	33.29	7.00e-117	414.00
IUUC-Cja-019063	Callithrix jacchus	46.96	0.00e+00	745.00
IUUC-Cfa-020976	Canis familiaris	49.34	0.00e+00	766.00
IUUC-Cpo-022265	Cavia porcellus	49.22	0.00e+00	766.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	42.81	3.00e-124	438.00
IUUC-Csa-024177	Chlorocebus sabaeus	49.52	0.00e+00	672.00
IUUC-Cho-024522	Choloepus hoffmanni	35.01	5.00e-126	444.00
IUUC-Cin-025411	Ciona intestinalis	44.09	0.00e+00	654.00
IUUC-Csv-026347	Ciona savignyi	43.86	0.00e+00	644.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	32.39	1.00e-100	359.00
IUUC-Cne-026831	Cryptococcus neoformans	35.61	6.00e-117	414.00
IUUC-Cme-027335	Cyanidioschyzon merolae	29.66	5.00e-35	142.00
IUUC-Dre-027651	Danio rerio	43.28	0.00e+00	702.00
IUUC-Dno-029034	Dasypus novemcinctus	48.24	0.00e+00	761.00
IUUC-Dor-030130	Dipodomys ordii	37.73	1.00e-105	377.00
IUUC-Dse-031467	Dothistroma septosporum	35.04	3.00e-117	415.00
IUUC-Dme-032075	Drosophila melanogaster	44.48	0.00e+00	663.00
IUUC-Ete-032865	Echinops telfairi	44.31	0.00e+00	664.00
IUUC-Eca-034059	Equus caballus	48.01	0.00e+00	756.00
IUUC-Eeu-035304	Erinaceus europaeus	45.54	0.00e+00	675.00
IUUC-Fca-035515	Felis catus	48.00	0.00e+00	759.00
IUUC-Fal-037271	Ficedula albicollis	49.31	0.00e+00	721.00
IUUC-Fox-037745	Fusarium oxysporum	34.74	1.00e-117	416.00
IUUC-Fso-038158	Fusarium solani	33.37	8.00e-112	397.00
IUUC-Gmo-039071	Gadus morhua	44.58	0.00e+00	663.00
IUUC-Ggr-040098	Gaeumannomyces graminis	32.52	3.00e-107	382.00
IUUC-Gga-040635	Gallus gallus	48.48	0.00e+00	776.00
IUUC-Gac-042528	Gasterosteus aculeatus	43.76	0.00e+00	674.00
IUUC-Gma-043614	Glycine max	68.11	0.00e+00	1110.00
IUUC-Ggo-044602	Gorilla gorilla	48.12	0.00e+00	758.00
IUUC-Hsa-045959	Homo sapiens	48.12	0.00e+00	758.00
IUUC-Hvu-047563	Hordeum vulgare	86.19	0.00e+00	1103.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	47.65	0.00e+00	762.00
IUUC-Kpa-049156	Komagataella pastoris	32.24	1.00e-105	376.00
IUUC-Lch-049648	Latimeria chalumnae	48.85	0.00e+00	761.00
IUUC-Lpe-051523	Leersia perrieri	91.07	0.00e+00	1495.00
IUUC-Loc-052072	Lepisosteus oculatus	43.58	0.00e+00	669.00
IUUC-Lma-053216	Leptosphaeria maculans	33.95	1.00e-106	381.00
IUUC-Laf-054327	Loxodonta africana	48.12	0.00e+00	761.00
IUUC-Mcc-055443	Macaca mulatta	48.00	0.00e+00	754.00
IUUC-Meu-056298	Macropus eugenii	51.03	1.00e-156	546.00
IUUC-Mor-057106	Magnaporthe oryzae	33.90	1.00e-114	406.00
IUUC-Mpo-057589	Magnaporthe poae	33.05	6.00e-109	387.00
IUUC-Mtr-058680	Medicago truncatula	67.99	0.00e+00	1136.00
IUUC-Mla-058903	Melampsora laricipopulina	33.33	2.00e-105	376.00
IUUC-Mga-059669	Meleagris gallopavo	47.95	0.00e+00	725.00
IUUC-Mvi-060476	Microbotryum violaceum	33.37	2.00e-102	366.00
IUUC-Mmr-060575	Microcebus murinus	48.24	0.00e+00	756.00
IUUC-Mdo-062183	Monodelphis domestica	48.51	0.00e+00	760.00
IUUC-Mmu-063592	Mus musculus	48.36	0.00e+00	762.00
IUUC-Mac-065634	Musa acuminata	75.30	0.00e+00	675.00
IUUC-Mpu-066082	Mustela putorius furo	49.34	0.00e+00	759.00
IUUC-Mlu-067345	Myotis lucifugus	47.31	0.00e+00	749.00
IUUC-Nfi-068558	Neosartorya fischeri	36.23	3.00e-120	425.00
IUUC-Ncr-068960	Neurospora crassa	31.25	2.00e-99	355.00
IUUC-Nle-070173	Nomascus leucogenys	49.34	0.00e+00	765.00
IUUC-Opr-070556	Ochotona princeps	47.89	0.00e+00	768.00
IUUC-Ont-071502	Oreochromis niloticus	46.23	0.00e+00	683.00
IUUC-Oan-072959	Ornithorhynchus anatinus	53.95	6.00e-67	246.00
IUUC-Ocu-074861	Oryctolagus cuniculus	49.10	0.00e+00	773.00
IUUC-Oba-075109	Oryza barthii	97.23	0.00e+00	1568.00
IUUC-Obr-076292	Oryza brachyantha	94.34	0.00e+00	1477.00
IUUC-Ogu-078776	Oryza glumaepatula	96.85	0.00e+00	1564.00
IUUC-Oin-080048	Oryza indica	99.12	0.00e+00	1592.00
IUUC-Olo-080711	Oryza longistaminata	94.68	0.00e+00	1440.00
IUUC-Ome-081506	Oryza meridionalis	96.95	0.00e+00	1454.00
IUUC-Oni-082320	Oryza nivara	94.61	0.00e+00	1559.00
IUUC-Opu-083801	Oryza punctata	95.34	0.00e+00	1491.00
IUUC-Oru-085139	Oryza rufipogon	94.49	0.00e+00	1556.00
IUUC-Osa-085713	Oryza sativa	99.75	0.00e+00	1624.00
IUUC-Ola-086951	Oryzias latipes	43.07	0.00e+00	656.00
IUUC-Olu-087822	Ostreococcus lucimarinus	41.66	2.00e-171	595.00
IUUC-Oga-088625	Otolemur garnettii	47.12	0.00e+00	748.00
IUUC-Oar-089995	Ovis aries	47.13	0.00e+00	747.00
IUUC-Ptr-090640	Pan troglodytes	47.18	0.00e+00	756.00
IUUC-Pan-091974	Papio anubis	47.19	0.00e+00	748.00
IUUC-Psi-093957	Pelodiscus sinensis	48.13	0.00e+00	780.00
IUUC-Pma-094242	Petromyzon marinus	47.29	1.00e-100	358.00
IUUC-Pno-094835	Phaeosphaeria nodorum	36.98	2.00e-99	355.00
IUUC-Ppa-095901	Physcomitrella patens	61.51	0.00e+00	1033.00
IUUC-Pfo-097148	Poecilia formosa	45.20	0.00e+00	678.00
IUUC-Pab-098068	Pongo abelii	43.14	0.00e+00	627.00
IUUC-Pop-098943	Populus trichocarpa	72.14	0.00e+00	1157.00
IUUC-Pca-100738	Procavia capensis	44.96	8.00e-142	496.00
IUUC-Ppe-101315	Prunus persica	70.25	0.00e+00	1140.00
IUUC-Pva-102154	Pteropus vampyrus	47.65	0.00e+00	749.00
IUUC-Pgr-103343	Puccinia graminis	33.14	5.00e-98	351.00
IUUC-Ptt-103928	Puccinia triticina	30.43	4.00e-94	338.00
IUUC-Pte-104306	Pyrenophora teres	33.53	3.00e-95	342.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	33.78	5.00e-98	351.00
IUUC-Rno-105801	Rattus norvegicus	48.36	0.00e+00	764.00
IUUC-Sce-106304	Saccharomyces cerevisiae	31.51	9.00e-74	270.00
IUUC-Sha-107635	Sarcophilus harrisii	49.40	0.00e+00	761.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	32.64	2.00e-96	346.00
IUUC-Spo-108144	Schizosaccharomyces pombe	33.21	2.00e-111	395.00
IUUC-Smo-108848	Selaginella moellendorffii	60.00	0.00e+00	943.00
IUUC-Sit-110728	Setaria italica	89.29	0.00e+00	1469.00
IUUC-Sly-111523	Solanum lycopersicum	67.20	0.00e+00	1150.00
IUUC-Sar-113733	Sorex araneus	45.48	4.00e-91	328.00
IUUC-Sbi-114419	Sorghum bicolor	89.42	0.00e+00	1459.00
IUUC-Sre-115225	Sporisorium reilianum	33.53	1.00e-105	376.00
IUUC-Ssc-115686	Sus scrofa	47.07	0.00e+00	754.00
IUUC-Tgu-117346	Taeniopygia guttata	48.30	0.00e+00	757.00
IUUC-Tru-118350	Takifugu rubripes	43.17	0.00e+00	660.00
IUUC-Tsy-119278	Tarsius syrichta	39.07	1.00e-162	565.00
IUUC-Tni-120658	Tetraodon nigroviridis	43.46	0.00e+00	647.00
IUUC-Tca-121585	Theobroma cacao	70.46	0.00e+00	1139.00
IUUC-Tre-122043	Trichoderma reesei	34.44	3.00e-113	402.00
IUUC-Tvi-122303	Trichoderma virens	34.23	7.00e-112	397.00
IUUC-Tae-123798	Triticum aestivum	88.29	0.00e+00	1445.00
IUUC-Tur-126732	Triticum urartu	82.62	0.00e+00	1343.00
IUUC-Tme-126909	Tuber melanosporum	33.49	5.00e-101	361.00
IUUC-Tbe-127261	Tupaia belangeri	40.73	4.00e-118	418.00
IUUC-Ttr-129119	Tursiops truncatus	54.20	7.00e-111	394.00
IUUC-Uma-129599	Ustilago maydis	34.30	3.00e-115	408.00
IUUC-Vda-129688	Verticillium dahliae	33.95	2.00e-108	386.00
IUUC-Vpa-130170	Vicugna pacos	36.74	2.00e-143	502.00
IUUC-Vvi-131116	Vitis vinifera	72.35	0.00e+00	1143.00
IUUC-Xtr-131953	Xenopus tropicalis	45.52	0.00e+00	714.00
IUUC-Xma-133837	Xiphophorus maculatus	45.08	0.00e+00	676.00
IUUC-Yli-134510	Yarrowia lipolytica	34.20	4.00e-108	385.00
IUUC-Zma-135786	Zea mays	87.15	0.00e+00	1392.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence