iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069524

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01122020

Gene Name

UBA2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000010670.2	ENSNLET00000013766.2	ENSNLEP00000013124.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.30e-135	452.8	10	420

Active Site

Position(s)	Description	Evidence
173	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR039133-1, ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 11   eaqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesite 99
           e  e++   +vl+vGagg+GcEllKnLvl+G+++i ++D dt++vsnlnrqFLf++++vg+sKA+va+e++ ++ p+ n++a+++si++
   Q: 10   ELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFYPKANIVAYHDSIMN 98
           56799999********************************************************************************* PP
   S: 100  leeeivFfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtie 188
           ++++++Ff++f +V++aldnr+ar++vnr+cl+a+vpliesgt G+lGqv++i kg+tecy+c+++p+q+t+P+ct+++tp+++ h+i+
   Q: 99   PDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIV 187
           ***************************************************************************************** PP
   S: 189  wa.vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttins.ikqllksfecdivtkskspfwv. 274
           wa +lfn+l++ee++++ev++  d++++e++++++++e+++++++++ ++++i++k++ak+t ++ +k ++k f++di++  ++++++ 
   Q: 188  WAkYLFNQLFGEEDADQEVSP--DRADPEAAWEPTEAEARARASNEDGDIKRISTKEWAKSTGYDpVKLFTKLFKDDIRYLLTMDKLWr 274
           *********************..799*************************************************************** PP
   S: 275  .................sfcsnaealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekdddsavdlvtaaan 341
                            +  + ++++++p+ + kd++v++++++     ++++++++++  k +g    el ++kdd+sa+d+vt+aan
   Q: 275  krkppvpldwaevqsqgEEMNASDQQNEPQLG-KDQQVLDVKSYarlfsKSIETLRVHLPPKGDGA---ELIWDKDDPSAMDFVTSAAN 359
           ***************97777777777777666.556778888888***99***************9...68****************** PP
   S: 342  lraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsgkfeplknfflfda 403
           lr++ +++++  ++++ik++agniipaiattnav++Gl+++E +K++sgk ++++++fl+++
   Q: 360  LRMHIFSMNM-KSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGKIDQCRTIFLNKQ 420
           **********.***********************************************9965 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MALSRGLPRE LAEAVAGGRV LVVGAGGIGC ELLKNLVLTG FSHIDLIDLD TIDVSNLNRQ 60
FLFQKKHVGR SKAQVAKESV LQFYPKANIV AYHDSIMNPD YNVEFFRQFI LVMNALDNRA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCCACCCGC TTCCGGCCGC GGCCAGGTTC TCCCGCCTCC GCCTCCGCCG CGGCTCGTGG 60
TTGTCCCGCC ATGGCACTGT CGCGGGGGCT GCCCCGGGAG CTGGCTGAGG CGGTGGCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016040--NAD(P)-bd_dom
IPR030661--SAE2/Uba2
IPR000594--ThiF_NAD_FAD-bd
IPR028077--UAE_UbL_dom
IPR032426--UBA2_C
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF00899--ThiF
PF14732--UAE_UbL
PF16195--UBA2_C

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0031510--C:SUMO activating enzyme complex
GO:0019948--F:SUMO activating enzyme activity
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000112	Aegilops tauschii	37.93	1.00e-107	383.00
IUUC-Aml-001662	Ailuropoda melanoleuca	96.72	0.00e+00	1231.00
IUUC-Atr-002636	Amborella trichopoda	39.46	8.00e-113	400.00
IUUC-Apl-003369	Anas platyrhynchos	88.55	0.00e+00	1014.00
IUUC-Aca-004490	Anolis carolinensis	83.06	0.00e+00	914.00
IUUC-Aly-006359	Arabidopsis lyrata	41.21	2.00e-102	366.00
IUUC-Ath-007667	Arabidopsis thaliana	41.76	6.00e-106	378.00
IUUC-Ago-007844	Ashbya gossypii	34.84	7.00e-86	311.00
IUUC-Acl-008270	Aspergillus clavatus	44.70	1.00e-103	370.00
IUUC-Afl-008674	Aspergillus flavus	43.22	2.00e-111	396.00
IUUC-Afu-008883	Aspergillus fumigatus	41.68	4.00e-106	379.00
IUUC-Ani-009500	Aspergillus nidulans	44.77	6.00e-114	404.00
IUUC-Ang-009535	Aspergillus niger	43.65	6.00e-110	391.00
IUUC-Aor-010223	Aspergillus oryzae	43.70	1.00e-112	400.00
IUUC-Ate-010282	Aspergillus terreus	43.88	3.00e-89	322.00
IUUC-Ame-011736	Astyanax mexicanus	77.81	0.00e+00	984.00
IUUC-Bgr-012166	Blumeria graminis	42.23	1.00e-98	353.00
IUUC-Bta-012589	Bos taurus	97.19	0.00e+00	1238.00
IUUC-Bci-013802	Botrytis cinerea	42.80	1.00e-100	360.00
IUUC-Bdi-014697	Brachypodium distachyon	39.56	3.00e-111	395.00
IUUC-Bol-016315	Brassica oleracea	41.68	1.00e-107	384.00
IUUC-Bra-017009	Brassica rapa	40.22	1.00e-108	387.00
IUUC-Cel-018708	Caenorhabditis elegans	46.57	3.00e-133	468.00
IUUC-Cja-019120	Callithrix jacchus	98.75	0.00e+00	1211.00
IUUC-Cfa-021061	Canis familiaris	97.19	0.00e+00	1239.00
IUUC-Cpo-021842	Cavia porcellus	97.03	0.00e+00	1194.00
IUUC-Csa-024104	Chlorocebus sabaeus	99.06	0.00e+00	1174.00
IUUC-Cho-024332	Choloepus hoffmanni	84.83	0.00e+00	860.00
IUUC-Cin-025363	Ciona intestinalis	62.17	0.00e+00	682.00
IUUC-Cgl-026419	Colletotrichum gloeosporioides	42.61	1.00e-97	350.00
IUUC-Cne-026888	Cryptococcus neoformans	51.97	1.00e-72	267.00
IUUC-Cme-027315	Cyanidioschyzon merolae	33.48	5.00e-60	225.00
IUUC-Dre-028420	Danio rerio	75.75	0.00e+00	911.00
IUUC-Dno-030041	Dasypus novemcinctus	96.41	0.00e+00	1189.00
IUUC-Dor-031039	Dipodomys ordii	81.09	0.00e+00	633.00
IUUC-Dse-031504	Dothistroma septosporum	35.34	4.00e-93	335.00
IUUC-Dme-031771	Drosophila melanogaster	50.73	6.00e-148	517.00
IUUC-Ete-033037	Echinops telfairi	90.62	0.00e+00	1065.00
IUUC-Eca-033774	Equus caballus	97.31	0.00e+00	1192.00
IUUC-Eeu-035074	Erinaceus europaeus	96.10	0.00e+00	956.00
IUUC-Fca-036508	Felis catus	97.47	0.00e+00	1195.00
IUUC-Fal-036813	Ficedula albicollis	86.49	0.00e+00	1009.00
IUUC-Fox-038056	Fusarium oxysporum	44.03	1.00e-106	380.00
IUUC-Fso-038223	Fusarium solani	42.59	4.00e-105	375.00
IUUC-Gmo-038526	Gadus morhua	74.57	0.00e+00	886.00
IUUC-Ggr-039767	Gaeumannomyces graminis	44.02	2.00e-101	363.00
IUUC-Gga-040981	Gallus gallus	87.62	0.00e+00	1038.00
IUUC-Gac-041437	Gasterosteus aculeatus	75.30	0.00e+00	911.00
IUUC-Gma-044072	Glycine max	37.56	8.00e-113	400.00
IUUC-Ggo-045358	Gorilla gorilla	95.67	0.00e+00	1118.00
IUUC-Hsa-046068	Homo sapiens	99.22	0.00e+00	1179.00
IUUC-Hvu-047646	Hordeum vulgare	38.13	6.00e-108	384.00
IUUC-Itr-047887	Ictidomys tridecemlineatus	96.88	0.00e+00	1186.00
IUUC-Lch-049565	Latimeria chalumnae	81.31	0.00e+00	1036.00
IUUC-Lpe-050884	Leersia perrieri	40.45	2.00e-108	386.00
IUUC-Loc-052493	Lepisosteus oculatus	81.11	0.00e+00	1011.00
IUUC-Lma-053117	Leptosphaeria maculans	44.52	8.00e-103	367.00
IUUC-Laf-054518	Loxodonta africana	93.45	0.00e+00	1165.00
IUUC-Mcc-055334	Macaca mulatta	98.75	0.00e+00	1174.00
IUUC-Mor-057137	Magnaporthe oryzae	43.61	2.00e-95	343.00
IUUC-Mpo-057449	Magnaporthe poae	42.43	2.00e-102	366.00
IUUC-Mtr-058045	Medicago truncatula	39.10	5.00e-117	414.00
IUUC-Mla-058864	Melampsora laricipopulina	45.51	1.00e-94	340.00
IUUC-Mga-059422	Meleagris gallopavo	82.38	0.00e+00	918.00
IUUC-Mvi-060536	Microbotryum violaceum	42.24	3.00e-87	315.00
IUUC-Mmr-061161	Microcebus murinus	95.71	0.00e+00	1193.00
IUUC-Mdo-061802	Monodelphis domestica	92.51	0.00e+00	1131.00
IUUC-Mmu-064357	Mus musculus	93.44	0.00e+00	1181.00
IUUC-Mac-065475	Musa acuminata	38.56	1.00e-110	393.00
IUUC-Mpu-066895	Mustela putorius furo	97.34	0.00e+00	1239.00
IUUC-Mlu-067862	Myotis lucifugus	96.41	0.00e+00	1233.00
IUUC-Nfi-068385	Neosartorya fischeri	44.55	3.00e-109	389.00
IUUC-Ncr-068885	Neurospora crassa	45.54	3.00e-106	379.00
IUUC-Opr-071038	Ochotona princeps	96.88	0.00e+00	1234.00
IUUC-Ont-071719	Oreochromis niloticus	75.79	0.00e+00	969.00
IUUC-Oan-072877	Ornithorhynchus anatinus	90.07	0.00e+00	981.00
IUUC-Ocu-074080	Oryctolagus cuniculus	96.56	0.00e+00	1184.00
IUUC-Oba-075936	Oryza barthii	37.66	2.00e-108	385.00
IUUC-Obr-076841	Oryza brachyantha	38.29	2.00e-110	392.00
IUUC-Ogl-077686	Oryza glaberrima	37.72	5.00e-110	391.00
IUUC-Ogu-078597	Oryza glumaepatula	36.79	1.00e-105	377.00
IUUC-Oin-079791	Oryza indica	37.66	2.00e-108	385.00
IUUC-Olo-081009	Oryza longistaminata	37.66	4.00e-108	385.00
IUUC-Ome-081327	Oryza meridionalis	35.21	1.00e-102	367.00
IUUC-Oni-082334	Oryza nivara	36.96	6.00e-106	378.00
IUUC-Opu-083447	Oryza punctata	37.97	1.00e-109	390.00
IUUC-Oru-084977	Oryza rufipogon	37.64	1.00e-107	384.00
IUUC-Osa-086160	Oryza sativa	43.49	5.00e-95	341.00
IUUC-Ola-087415	Oryzias latipes	75.08	0.00e+00	932.00
IUUC-Olu-087850	Ostreococcus lucimarinus	39.66	7.00e-100	357.00
IUUC-Oga-088434	Otolemur garnettii	97.19	0.00e+00	1197.00
IUUC-Oar-089872	Ovis aries	96.64	0.00e+00	1182.00
IUUC-Ptr-091212	Pan troglodytes	99.22	0.00e+00	1179.00
IUUC-Pan-092708	Papio anubis	99.61	6.00e-133	467.00
IUUC-Psi-093703	Pelodiscus sinensis	90.24	0.00e+00	1036.00
IUUC-Pno-094953	Phaeosphaeria nodorum	45.41	6.00e-105	374.00
IUUC-Ppa-095963	Physcomitrella patens	43.86	8.00e-108	384.00
IUUC-Pfo-097515	Poecilia formosa	74.41	0.00e+00	920.00
IUUC-Pab-097951	Pongo abelii	99.26	0.00e+00	1028.00
IUUC-Pop-099703	Populus trichocarpa	36.63	8.00e-96	344.00
IUUC-Pca-100426	Procavia capensis	94.22	0.00e+00	1195.00
IUUC-Ppe-101152	Prunus persica	39.05	7.00e-111	394.00
IUUC-Pva-102792	Pteropus vampyrus	92.27	0.00e+00	1141.00
IUUC-Pgr-103592	Puccinia graminis	43.35	7.00e-100	358.00
IUUC-Ptt-103805	Puccinia triticina	41.48	2.00e-85	310.00
IUUC-Pte-104215	Pyrenophora teres	44.79	1.00e-111	397.00
IUUC-Pyt-104634	Pyrenophora triticirepentis	46.12	8.00e-110	390.00
IUUC-Rno-106117	Rattus norvegicus	93.91	0.00e+00	1188.00
IUUC-Sce-106177	Saccharomyces cerevisiae	33.80	1.00e-76	280.00
IUUC-Sha-107006	Sarcophilus harrisii	92.68	0.00e+00	1134.00
IUUC-Sja-107967	Schizosaccharomyces japonicus	44.06	1.00e-94	340.00
IUUC-Spo-108020	Schizosaccharomyces pombe	44.68	2.00e-95	342.00
IUUC-Ssl-108509	Sclerotinia sclerotiorum	43.54	3.00e-104	372.00
IUUC-Smo-109264	Selaginella moellendorffii	43.38	6.00e-106	377.00
IUUC-Sit-110581	Setaria italica	40.48	2.00e-108	386.00
IUUC-Sly-111870	Solanum lycopersicum	39.44	3.00e-111	395.00
IUUC-Stu-112283	Solanum tuberosum	39.21	2.00e-108	386.00
IUUC-Sar-113432	Sorex araneus	71.92	0.00e+00	784.00
IUUC-Sbi-114075	Sorghum bicolor	37.96	1.00e-109	390.00
IUUC-Sre-114926	Sporisorium reilianum	42.12	2.00e-103	369.00
IUUC-Ssc-116281	Sus scrofa	98.62	4.00e-118	416.00
IUUC-Tgu-117247	Taeniopygia guttata	85.04	0.00e+00	1005.00
IUUC-Tru-118075	Takifugu rubripes	70.84	0.00e+00	882.00
IUUC-Tsy-119398	Tarsius syrichta	81.09	0.00e+00	918.00
IUUC-Tni-120771	Tetraodon nigroviridis	65.29	0.00e+00	795.00
IUUC-Tca-121651	Theobroma cacao	39.37	3.00e-110	392.00
IUUC-Tre-122224	Trichoderma reesei	42.39	1.00e-96	347.00
IUUC-Tvi-122634	Trichoderma virens	42.86	7.00e-96	344.00
IUUC-Tae-125665	Triticum aestivum	39.93	5.00e-105	374.00
IUUC-Tur-126417	Triticum urartu	38.99	7.00e-106	377.00
IUUC-Tme-127016	Tuber melanosporum	45.05	8.00e-97	347.00
IUUC-Tbe-127678	Tupaia belangeri	95.58	1.00e-162	566.00
IUUC-Ttr-128598	Tursiops truncatus	93.12	0.00e+00	1175.00
IUUC-Uma-129612	Ustilago maydis	41.70	4.00e-96	345.00
IUUC-Vda-129811	Verticillium dahliae	39.38	1.00e-102	366.00
IUUC-Vpa-130732	Vicugna pacos	83.12	0.00e+00	1018.00
IUUC-Vvi-130832	Vitis vinifera	40.33	1.00e-105	377.00
IUUC-Xtr-132823	Xenopus tropicalis	75.63	0.00e+00	910.00
IUUC-Xma-133552	Xiphophorus maculatus	74.25	0.00e+00	920.00
IUUC-Yli-134666	Yarrowia lipolytica	37.53	1.00e-76	281.00
IUUC-Zma-135547	Zea mays	37.96	5.00e-108	384.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence