iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088351

Ensembl Protein ID

ENSOGAP00000012510.2

UniProt Accession

H0XA78; H0XA78_OTOGA

Genbank Protein ID

ENSOGAP00000012510

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03177350

Gene Name

MAP3K10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000013974.2	ENSOGAT00000013977.2	ENSOGAP00000012510.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	7.90e-15	54.6	23	78

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlvieke...eqdegWlkgvkelegkrGlfPenFve 60
            + +dyea+ d+eLtl++Gd v+v++++   + degW+ g+   +g+ G+fP+n+v+
   Q: 23   TAVFDYEAAGDEELTLRRGDRVQVLSQDcavSGDEGWWTGQ-LPSGRVGVFPSNYVA 78
           589**********************77622257*******7.99***********97 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MEEEEEGAAA KEWGTTPTGP VWTAVFDYEA AGDEELTLRR GDRVQVLSQD CAVSGDEGWW 60
TGQLPSGRVG VFPSNYVAPS TPAAPVGLQL PQEIPFHELQ LEEIIGVGGF GKVYRALWRG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATTTTTTCT TGCTCCTGCG GAGGGACCCC CAGCCATGAC CCCCAGGAGT CCCCTAGAGC 60
CCGCAGGGAC TGCCCTTCAT CCTGGCCGCC TGGGCCTGCC CTTTGCATCC CGCGGGCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR015785--MAP3K10
IPR016231--MLK1/MLK2/MLK4
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR008271--Ser/Thr_kinase_AS
IPR001452--SH3_domain

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00220--S_TKc
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004709--F:MAP kinase kinase kinase activity
GO:0003714--F:transcription corepressor activity
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0018105--P:peptidyl-serine phosphorylation
GO:0018107--P:peptidyl-threonine phosphorylation
GO:0043507--P:positive regulation of JUN kinase activity
GO:0007224--P:smoothened signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001187	Ailuropoda melanoleuca	95.85	0.00e+00	1008.00
IUUC-Atr-002967	Amborella trichopoda	31.27	4.00e-24	105.00
IUUC-Aca-004768	Anolis carolinensis	72.74	0.00e+00	826.00
IUUC-Aly-006459	Arabidopsis lyrata	33.10	2.00e-29	124.00
IUUC-Ath-006581	Arabidopsis thaliana	32.74	1.00e-28	122.00
IUUC-Bta-013545	Bos taurus	97.64	0.00e+00	841.00
IUUC-Bdi-014449	Brachypodium distachyon	32.36	7.00e-26	112.00
IUUC-Bol-016287	Brassica oleracea	32.03	2.00e-28	120.00
IUUC-Bra-016997	Brassica rapa	33.33	2.00e-28	121.00
IUUC-Cja-019696	Callithrix jacchus	86.80	0.00e+00	1274.00
IUUC-Cfa-020789	Canis familiaris	78.98	0.00e+00	1080.00
IUUC-Cpo-021993	Cavia porcellus	77.80	0.00e+00	1169.00
IUUC-Csa-024243	Chlorocebus sabaeus	91.95	0.00e+00	1327.00
IUUC-Cho-024961	Choloepus hoffmanni	91.90	1.00e-112	400.00
IUUC-Dre-028573	Danio rerio	72.56	0.00e+00	791.00
IUUC-Dno-029095	Dasypus novemcinctus	89.72	0.00e+00	1213.00
IUUC-Dme-032210	Drosophila melanogaster	49.16	3.00e-141	496.00
IUUC-Fca-036250	Felis catus	95.09	0.00e+00	974.00
IUUC-Gmo-038497	Gadus morhua	72.94	0.00e+00	784.00
IUUC-Gac-042509	Gasterosteus aculeatus	64.57	0.00e+00	768.00
IUUC-Gma-043336	Glycine max	29.39	1.00e-25	112.00
IUUC-Ggo-045471	Gorilla gorilla	90.39	0.00e+00	906.00
IUUC-Hsa-046936	Homo sapiens	92.80	0.00e+00	1336.00
IUUC-Hvu-047798	Hordeum vulgare	32.27	2.00e-24	107.00
IUUC-Itr-048231	Ictidomys tridecemlineatus	95.68	0.00e+00	983.00
IUUC-Lch-049935	Latimeria chalumnae	63.96	0.00e+00	973.00
IUUC-Loc-052286	Lepisosteus oculatus	68.88	0.00e+00	769.00
IUUC-Mcc-055733	Macaca mulatta	88.84	0.00e+00	1319.00
IUUC-Mtr-058733	Medicago truncatula	32.00	4.00e-26	113.00
IUUC-Mdo-062516	Monodelphis domestica	73.40	0.00e+00	1051.00
IUUC-Mmu-064082	Mus musculus	89.26	0.00e+00	1402.00
IUUC-Mac-065156	Musa acuminata	31.58	9.00e-27	115.00
IUUC-Mpu-065934	Mustela putorius furo	91.39	0.00e+00	1297.00
IUUC-Mlu-068137	Myotis lucifugus	79.61	0.00e+00	1226.00
IUUC-Opr-070869	Ochotona princeps	77.04	0.00e+00	891.00
IUUC-Ont-072492	Oreochromis niloticus	64.89	0.00e+00	801.00
IUUC-Ocu-074350	Oryctolagus cuniculus	89.64	0.00e+00	1213.00
IUUC-Oba-075616	Oryza barthii	34.88	2.00e-24	108.00
IUUC-Obr-076215	Oryza brachyantha	31.79	8.00e-26	112.00
IUUC-Ogl-077159	Oryza glaberrima	34.88	1.00e-24	108.00
IUUC-Ogu-078228	Oryza glumaepatula	35.35	4.00e-25	110.00
IUUC-Oin-079079	Oryza indica	34.93	4.00e-25	110.00
IUUC-Olo-080309	Oryza longistaminata	35.07	6.00e-24	105.00
IUUC-Oni-082428	Oryza nivara	34.88	2.00e-24	107.00
IUUC-Opu-083527	Oryza punctata	35.35	1.00e-24	108.00
IUUC-Oru-084678	Oryza rufipogon	34.93	4.00e-25	110.00
IUUC-Osa-086117	Oryza sativa	34.93	4.00e-25	110.00
IUUC-Ola-087224	Oryzias latipes	58.41	0.00e+00	877.00
IUUC-Ptr-091607	Pan troglodytes	92.90	0.00e+00	1338.00
IUUC-Pan-092403	Papio anubis	93.21	0.00e+00	962.00
IUUC-Pfo-096104	Poecilia formosa	59.45	0.00e+00	800.00
IUUC-Pab-098396	Pongo abelii	93.29	0.00e+00	995.00
IUUC-Pop-099554	Populus trichocarpa	29.55	8.00e-24	105.00
IUUC-Ppe-101208	Prunus persica	32.28	3.00e-26	114.00
IUUC-Rno-105688	Rattus norvegicus	89.26	0.00e+00	1408.00
IUUC-Smo-109113	Selaginella moellendorffii	32.72	2.00e-25	109.00
IUUC-Sit-110451	Setaria italica	32.36	3.00e-25	110.00
IUUC-Sly-111528	Solanum lycopersicum	31.31	3.00e-25	110.00
IUUC-Stu-112224	Solanum tuberosum	35.09	8.00e-25	109.00
IUUC-Sbi-113963	Sorghum bicolor	35.05	2.00e-25	110.00
IUUC-Ssc-115332	Sus scrofa	95.02	0.00e+00	997.00
IUUC-Tru-117692	Takifugu rubripes	63.13	0.00e+00	801.00
IUUC-Tsy-119412	Tarsius syrichta	92.65	1.00e-71	264.00
IUUC-Tni-120689	Tetraodon nigroviridis	62.62	0.00e+00	795.00
IUUC-Tca-121461	Theobroma cacao	32.31	3.00e-26	113.00
IUUC-Tae-125555	Triticum aestivum	32.10	6.00e-25	109.00
IUUC-Tur-126322	Triticum urartu	32.26	2.00e-25	110.00
IUUC-Tbe-127643	Tupaia belangeri	97.08	0.00e+00	659.00
IUUC-Ttr-128550	Tursiops truncatus	91.19	0.00e+00	1340.00
IUUC-Vvi-131372	Vitis vinifera	32.62	4.00e-24	106.00
IUUC-Xtr-132108	Xenopus tropicalis	63.33	0.00e+00	996.00
IUUC-Xma-134254	Xiphophorus maculatus	60.58	0.00e+00	827.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence