iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sly-111759

Ensembl Protein ID

Solyc04g080980.2.1

UniProt Accession

K4BVH7; K4BVH7_SOLLC

Protein Name

Coatomer subunit alpha

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Solyc04g080980.2	Solyc04g080980.2.1	Solyc04g080980.2.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.60e-37	126.0	50	85
UBD/Beta-Prp	1.40e-76	258.3	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtgvl 35
           H ++v++++f  s +l+vsG+dD +ikvW+++ +++
   Q: 50   HDGPVRGVHFhkSQPLFVSGGDDYKIKVWNYKLHRC 85
           99*********7559***************876666 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghe 94
           t +++++++++ + f+ ++++++++  +g i++wd+++g+l+ ++ +h+++v+ v f+++++++v+g++D+ ikvw+++   c+ tl gh 
   Q: 3    TKFETKSNRVKGLSFHSKRPWILASLHSGVIQLWDYRMGTLIDRFDEHDGPVRGVHFHKSQPLFVSGGDDYKIKVWNYKLHRCLFTLLGHL 93
           67889999*********************************************************************************** PP
   S: 95   dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl................... 166
           d++++++f+ +  ++vs+s+d+tir+w++++++c++ +l+gh++ v+c+ +hp+++l+vs+slD+tvr+Wd+                   
   Q: 94   DYIRTVQFHHEYPWIVSASDDQTIRIWNWQSRTCIS-VLTGHNHYVMCALFHPKEDLVVSASLDQTVRVWDIgalrkktvspaddilrlsq 183
           ************************************.**************************************************5555 PP
   S: 167  .......ktgkllrtl........tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsg 240
                                   +g h++ v++ sf+++ + +vsg++d++vk+w +  ++   v+tl+gh +nv++v f+++++++vs 
   Q: 184  mntdffgG-------VdavvkyvlEG-HDRGVNWASFHPTLPLIVSGADDRQVKIWRMNDTKAweVDTLRGHMNNVSCVLFHSRQDIIVSN 266
           55555552.......05555555365.********************************777668************************** PP
   S: 241  ssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           s+D+sir+Wd ++++ l+t+ +++++++  a+ +++ n l++g  ds   ++kl++++p
   Q: 267  SEDKSIRVWDATKRTGLQTFRREHDRFWILAA-HPEMNLLAAG-HDSGMIVFKLERERP 323
           ********************************.6666655555.689999999988765 PP

Organism

Solanum lycopersicum

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLSFHSK RPWILASLHS GVIQLWDYRM GTLIDRFDEH DGPVRGVHFH 60
KSQPLFVSGG DDYKIKVWNY KLHRCLFTLL GHLDYIRTVQ FHHEYPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATATTATTC TTCTGTCTAT CAAACTTCCG ATCCCCAATT TCTTTAACGC CACACTAAAA 60
AAACACACAA AGAGACAACT TCCCTTAACA TACGCACTCT CCGTTCACCG ATCTTCATTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

sly:101251283

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002493	Amborella trichopoda	81.53	0.00e+00	2010.00
IUUC-Apl-003385	Anas platyrhynchos	49.63	0.00e+00	1047.00
IUUC-Aca-005154	Anolis carolinensis	77.99	4.00e-96	342.00
IUUC-Aly-006020	Arabidopsis lyrata	82.36	0.00e+00	2040.00
IUUC-Ath-007058	Arabidopsis thaliana	82.20	0.00e+00	2039.00
IUUC-Ani-009379	Aspergillus nidulans	55.48	0.00e+00	982.00
IUUC-Bci-013781	Botrytis cinerea	47.20	0.00e+00	1119.00
IUUC-Bdi-014549	Brachypodium distachyon	77.95	0.00e+00	2020.00
IUUC-Bol-015925	Brassica oleracea	81.10	0.00e+00	2006.00
IUUC-Bra-016978	Brassica rapa	81.57	0.00e+00	2021.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	72.48	0.00e+00	1289.00
IUUC-Cho-024704	Choloepus hoffmanni	69.77	3.00e-133	469.00
IUUC-Cin-025572	Ciona intestinalis	50.88	0.00e+00	1246.00
IUUC-Csv-025864	Ciona savignyi	58.10	0.00e+00	991.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	55.44	0.00e+00	979.00
IUUC-Cne-027053	Cryptococcus neoformans	51.69	0.00e+00	1200.00
IUUC-Dse-031543	Dothistroma septosporum	46.18	0.00e+00	1057.00
IUUC-Eeu-034874	Erinaceus europaeus	42.39	0.00e+00	672.00
IUUC-Fal-037263	Ficedula albicollis	51.42	0.00e+00	1218.00
IUUC-Fox-037738	Fusarium oxysporum	47.49	0.00e+00	1123.00
IUUC-Ggr-039931	Gaeumannomyces graminis	54.24	0.00e+00	965.00
IUUC-Gga-040590	Gallus gallus	55.00	0.00e+00	1374.00
IUUC-Gma-043894	Glycine max	82.61	0.00e+00	2080.00
IUUC-Hvu-047556	Hordeum vulgare	78.20	0.00e+00	2012.00
IUUC-Lch-049706	Latimeria chalumnae	55.29	0.00e+00	1363.00
IUUC-Lpe-051316	Leersia perrieri	78.61	0.00e+00	1993.00
IUUC-Loc-051867	Lepisosteus oculatus	51.05	0.00e+00	831.00
IUUC-Lma-053138	Leptosphaeria maculans	54.88	0.00e+00	991.00
IUUC-Laf-053510	Loxodonta africana	56.24	0.00e+00	1397.00
IUUC-Mor-057172	Magnaporthe oryzae	46.50	0.00e+00	1105.00
IUUC-Mpo-057300	Magnaporthe poae	46.48	0.00e+00	1099.00
IUUC-Mtr-058248	Medicago truncatula	81.71	0.00e+00	2076.00
IUUC-Mla-059019	Melampsora laricipopulina	50.69	0.00e+00	1234.00
IUUC-Mga-059499	Meleagris gallopavo	54.91	0.00e+00	1370.00
IUUC-Mvi-060336	Microbotryum violaceum	52.02	0.00e+00	1233.00
IUUC-Mac-065398	Musa acuminata	74.96	0.00e+00	1867.00
IUUC-Mpu-066701	Mustela putorius furo	55.64	0.00e+00	1373.00
IUUC-Mlu-067392	Myotis lucifugus	55.49	0.00e+00	1363.00
IUUC-Nle-069634	Nomascus leucogenys	66.22	0.00e+00	946.00
IUUC-Opr-070952	Ochotona princeps	42.58	0.00e+00	659.00
IUUC-Oba-075761	Oryza barthii	79.00	0.00e+00	1997.00
IUUC-Obr-076429	Oryza brachyantha	84.04	0.00e+00	1505.00
IUUC-Ogl-077364	Oryza glaberrima	84.73	0.00e+00	1511.00
IUUC-Ogu-078257	Oryza glumaepatula	84.61	0.00e+00	1509.00
IUUC-Oin-079274	Oryza indica	84.61	0.00e+00	1510.00
IUUC-Olo-080466	Oryza longistaminata	84.33	0.00e+00	1493.00
IUUC-Ome-081993	Oryza meridionalis	84.87	0.00e+00	1392.00
IUUC-Oni-082874	Oryza nivara	84.73	0.00e+00	1511.00
IUUC-Opu-083885	Oryza punctata	79.67	0.00e+00	2006.00
IUUC-Oru-084274	Oryza rufipogon	84.61	0.00e+00	1509.00
IUUC-Osa-085565	Oryza sativa	84.61	0.00e+00	1509.00
IUUC-Olu-087639	Ostreococcus lucimarinus	62.67	0.00e+00	1585.00
IUUC-Psi-093044	Pelodiscus sinensis	55.97	0.00e+00	915.00
IUUC-Ppa-095254	Physcomitrella patens	71.50	0.00e+00	1825.00
IUUC-Pop-099992	Populus trichocarpa	85.06	0.00e+00	2094.00
IUUC-Pca-100413	Procavia capensis	60.79	0.00e+00	695.00
IUUC-Ppe-101392	Prunus persica	86.62	0.00e+00	2204.00
IUUC-Pgr-103376	Puccinia graminis	50.45	0.00e+00	1236.00
IUUC-Pte-104126	Pyrenophora teres	54.84	0.00e+00	948.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	45.94	3.00e-178	618.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	44.68	0.00e+00	1064.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	47.24	0.00e+00	1123.00
IUUC-Sit-109697	Setaria italica	79.30	0.00e+00	1996.00
IUUC-Stu-112564	Solanum tuberosum	98.93	0.00e+00	2440.00
IUUC-Sbi-114388	Sorghum bicolor	79.21	0.00e+00	1990.00
IUUC-Sre-115209	Sporisorium reilianum	55.57	0.00e+00	1011.00
IUUC-Tgu-117109	Taeniopygia guttata	43.69	9.00e-114	402.00
IUUC-Tsy-119105	Tarsius syrichta	53.22	0.00e+00	1055.00
IUUC-Tni-120556	Tetraodon nigroviridis	41.94	0.00e+00	882.00
IUUC-Tca-121545	Theobroma cacao	84.25	0.00e+00	2144.00
IUUC-Tre-121951	Trichoderma reesei	55.32	0.00e+00	972.00
IUUC-Tvi-122359	Trichoderma virens	46.35	0.00e+00	1115.00
IUUC-Tae-125527	Triticum aestivum	77.36	0.00e+00	1976.00
IUUC-Tur-126754	Triticum urartu	76.21	0.00e+00	1932.00
IUUC-Tbe-127882	Tupaia belangeri	69.68	2.00e-129	456.00
IUUC-Uma-129337	Ustilago maydis	56.16	0.00e+00	1012.00
IUUC-Vda-129828	Verticillium dahliae	53.25	0.00e+00	948.00
IUUC-Vvi-130958	Vitis vinifera	86.12	0.00e+00	2156.00
IUUC-Zma-135612	Zea mays	77.93	0.00e+00	2002.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence