iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059738

UUCD1 version

UUC-MeG-00776

Ensembl Protein ID

ENSMGAP00000008612.2

UniProt Accession

G1N8H4; G1N8H4_MELGA

Protein Name

Uncharacterized protein

Gene Name

UBE2A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000017165.1	ENSMGAT00000009412.2	ENSMGAP00000008612.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.30e-39	134.9	1	92

Active Site

Position(s)	Description	Evidence
38	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 45   gvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsvesvllsiqsllaepnpesplneeaaellkknreey 133
           g+Fkl+ief+e+YP kPP+v+f++k+fhPnvy++G++Cl+il+  ++Wsp+++v+s+l+siqsll+epnp+sp+n++aa+l+++n++ey
   Q: 1    GTFKLTIEFTEEYPNKPPTVRFVSKMFHPNVYADGSICLDILQ--NRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREY 87
           78****************************************9..******************************************** PP
   S: 134  kkkvr 138
           +k+v+
   Q: 88   EKRVS 92
           **996 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

GTFKLTIEFT EEYPNKPPTV RFVSKMFHPN VYADGSICLD ILQNRWSPTY DVSSILTSIQ 60
SLLDEPNPNS PANSQAAQLY QENKREYEKR VSAIVEQSWR DC 102

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAACATTCA AACTTACAAT AGAATTCACA GAAGAATATC CAAATAAGCC ACCTACTGTT 60
AGATTTGTCT CTAAAATGTT TCATCCAAAT GGTAAGTATT TACACAGTAC ATTTAATTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0033503--C:HULC complex
GO:0000790--C:nuclear chromatin
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0006281--P:DNA repair
GO:0033522--P:histone H2A ubiquitination
GO:0008284--P:positive regulation of cell proliferation
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0009411--P:response to UV

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000296	Aegilops tauschii	78.79	5.00e-46	176.00
IUUC-Oan-073152	Ornithorhynchus anatinus	100.00	6.00e-58	214.00
IUUC-Olo-080729	Oryza longistaminata	78.79	7.00e-46	176.00
IUUC-Vpa-130366	Vicugna pacos	100.00	6.00e-57	212.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence