iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088266

Ensembl Protein ID

ENSOGAP00000005497.2

UniProt Accession

H0WTK8; H0WTK8_OTOGA

Genbank Protein ID

ENSOGAP00000005497

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03150515

Gene Name

CRK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000006159.2	ENSOGAT00000006158.2	ENSOGAP00000005497.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.40e-18	66.6	134	189

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            e+v++l+d++++++++L +kkGd++++   ++ +e W+++ ++ egkrG++P  +vek
   Q: 134  AEYVRALFDFNGNDEEDLPFKKGDILRI--RDKPEEQWWNA-EDSEGKRGMIPVPYVEK 189
           689*************************..6999******9.5**************98 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MAGNFDSEER SSWYWGRLSR QEAVAMLQGQ RHGVFLVRDS STSPGDYVLS VSENSRVSHY 60
IINSSGPRPP VPPSPAQPPP AVSPSRLRIG DQEFDSLPAL LEFYKIHYLD TTTLIEPVSR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGCTGAGA CCGGAGCCGG TCCGCTGGGC GGCGGGCGCC GGGGCTGGAG GGTCGCGCGT 60
GGCGGCTGCC CAGCGTGTAG GCGCAGAGGC GGCCATGGCA GGCAACTTCG ATTCGGAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0070062--C:extracellular exosome
GO:0048013--P:ephrin receptor signaling pathway
GO:0009967--P:positive regulation of signal transduction
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:0032956--P:regulation of actin cytoskeleton organization
GO:0043087--P:regulation of GTPase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001192	Ailuropoda melanoleuca	98.33	1.00e-159	555.00
IUUC-Apl-003225	Anas platyrhynchos	92.38	3.00e-122	430.00
IUUC-Aca-004818	Anolis carolinensis	78.35	3.00e-93	333.00
IUUC-Ame-011721	Astyanax mexicanus	68.35	1.00e-117	415.00
IUUC-Bta-012320	Bos taurus	98.68	7.00e-163	565.00
IUUC-Cja-019935	Callithrix jacchus	95.39	2.00e-166	577.00
IUUC-Cfa-021221	Canis familiaris	98.36	6.00e-163	566.00
IUUC-Cpo-021592	Cavia porcellus	85.47	3.00e-136	477.00
IUUC-Csa-024128	Chlorocebus sabaeus	98.03	7.00e-100	355.00
IUUC-Cho-024775	Choloepus hoffmanni	96.05	3.00e-161	560.00
IUUC-Dre-027390	Danio rerio	68.32	8.00e-119	419.00
IUUC-Dno-029847	Dasypus novemcinctus	98.68	7.00e-163	565.00
IUUC-Dor-030360	Dipodomys ordii	88.82	3.00e-155	540.00
IUUC-Ete-032604	Echinops telfairi	95.95	5.00e-125	439.00
IUUC-Eca-033233	Equus caballus	97.04	3.00e-161	560.00
IUUC-Eeu-034642	Erinaceus europaeus	96.85	3.00e-127	446.00
IUUC-Fca-035955	Felis catus	98.22	4.00e-130	456.00
IUUC-Fal-037152	Ficedula albicollis	87.19	1.00e-141	495.00
IUUC-Gmo-038849	Gadus morhua	67.09	7.00e-117	413.00
IUUC-Gga-040861	Gallus gallus	83.93	3.00e-150	524.00
IUUC-Gac-041627	Gasterosteus aculeatus	65.73	6.00e-119	420.00
IUUC-Ggo-045475	Gorilla gorilla	98.68	7.00e-163	565.00
IUUC-Hsa-046008	Homo sapiens	98.68	7.00e-163	565.00
IUUC-Itr-048906	Ictidomys tridecemlineatus	98.08	2.00e-133	468.00
IUUC-Lch-050509	Latimeria chalumnae	80.97	4.00e-148	517.00
IUUC-Loc-052229	Lepisosteus oculatus	72.79	3.00e-107	380.00
IUUC-Laf-053896	Loxodonta africana	93.81	9.00e-165	572.00
IUUC-Mcc-055280	Macaca mulatta	98.68	7.00e-163	565.00
IUUC-Meu-056783	Macropus eugenii	96.40	5.00e-126	442.00
IUUC-Mga-059345	Meleagris gallopavo	92.76	3.00e-123	434.00
IUUC-Mdo-062691	Monodelphis domestica	87.01	5.00e-152	530.00
IUUC-Mmu-063691	Mus musculus	98.36	1.00e-162	565.00
IUUC-Mpu-065737	Mustela putorius furo	98.36	7.00e-163	565.00
IUUC-Mlu-067005	Myotis lucifugus	96.38	6.00e-159	552.00
IUUC-Nle-070154	Nomascus leucogenys	98.22	7.00e-130	456.00
IUUC-Opr-071114	Ochotona princeps	97.04	4.00e-164	570.00
IUUC-Ont-071696	Oreochromis niloticus	68.79	2.00e-115	407.00
IUUC-Oan-072967	Ornithorhynchus anatinus	92.69	3.00e-132	464.00
IUUC-Ocu-074025	Oryctolagus cuniculus	97.04	1.00e-98	351.00
IUUC-Olo-080293	Oryza longistaminata	40.00	1.70e+00	26.20
IUUC-Oar-089221	Ovis aries	97.05	3.00e-158	550.00
IUUC-Ptr-091463	Pan troglodytes	94.08	9.00e-151	525.00
IUUC-Pan-092242	Papio anubis	98.36	7.00e-163	565.00
IUUC-Psi-093287	Pelodiscus sinensis	94.14	2.00e-125	440.00
IUUC-Pfo-097378	Poecilia formosa	66.14	2.00e-110	391.00
IUUC-Pab-097823	Pongo abelii	98.03	7.00e-100	355.00
IUUC-Pca-101068	Procavia capensis	98.68	7.00e-163	565.00
IUUC-Rno-105288	Rattus norvegicus	98.36	1.00e-162	565.00
IUUC-Sar-113453	Sorex araneus	83.55	2.00e-145	508.00
IUUC-Tgu-116926	Taeniopygia guttata	86.56	1.00e-150	525.00
IUUC-Tru-118656	Takifugu rubripes	66.26	2.00e-118	418.00
IUUC-Tni-120497	Tetraodon nigroviridis	67.52	3.00e-114	404.00
IUUC-Tbe-127436	Tupaia belangeri	94.41	1.00e-144	505.00
IUUC-Ttr-129109	Tursiops truncatus	99.10	7.00e-130	455.00
IUUC-Vpa-130527	Vicugna pacos	98.36	8.00e-161	559.00
IUUC-Xtr-131808	Xenopus tropicalis	83.28	3.00e-148	517.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence