iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-091227

Ensembl Protein ID

ENSPTRP00000043417.4

UniProt Accession

H2R255; H2R255_PANTR

Genbank Protein ID

JAA03211.1; JAA03212.1; JAA13262.1; JAA13263.1; JAA28585.1; JAA28586.1; JAA35740.1; JAA35741.1

Protein Name

Ubiquitin interaction motif containing 1

Genbank Nucleotide ID

AACZ03043122; GABC01008126; GABF01008883; GABF01008882; GABD01004515; GABD01004514; GABE01008999; GABE01008998

Gene Name

UIMC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000017572.5	ENSPTRT00000032478.5	ENSPTRP00000043417.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UIM	7.60e-06	25.4	105	123
UBD/Alpha-Helix/UIM	6.7e-05	13.2	80	98

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UIM

   S: 1    dEdeeLqlAlalSlqEeee 19
           +E+e+L++A+a+Sl+ ++ 
   Q: 105  EEEELLRKAIAESLNSCRP 123
           7*************99875 PP

UBD/Alpha-Helix/UIM

   S: 1    dEdeeLqlAlalSlqEeee 19
           +E+e+++lAl +S qE++e
   Q: 80   TEEEQFALALKMSEQEARE 98
           59**************986 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MPRRKKKVKE VSESRNLEKK DVETTSSVSV KRKRRLEDAF IVISDSDGEE PKEENGLQKT 60
KTKQSNRAKC LAKRKIAQMT EEEQFALALK MSEQEAREVN SQEEEEEELL RKAIAESLNS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTCGCCGCG CCTGCGCCCG CCCCGAGAGC GTGTCTCTGG CATCGGACGC GCGCGCCCGT 60
CCCCTTCCCC CCGCGCTCCC AACGTGTGGC GGCTCGCGAC CCCCAGCAAC CCGGAGAAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003903--UIM_dom

PROSITE

PS50330--UIM

SMART

SM00726--UIM

Gene Ontology

GO:0070531--C:BRCA1-A complex
GO:0016604--C:nuclear body
GO:0042393--F:histone binding
GO:0070530--F:K63-linked polyubiquitin binding
GO:0006302--P:double-strand break repair
GO:0031572--P:G2 DNA damage checkpoint
GO:0070537--P:histone H2A K63-linked deubiquitination
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045739--P:positive regulation of DNA repair
GO:0010212--P:response to ionizing radiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002335	Ailuropoda melanoleuca	86.84	0.00e+00	1095.00
IUUC-Apl-003971	Anas platyrhynchos	44.44	8.00e-96	344.00
IUUC-Aca-004239	Anolis carolinensis	42.06	3.00e-111	395.00
IUUC-Ame-011593	Astyanax mexicanus	49.37	2.00e-18	88.60
IUUC-Bta-012883	Bos taurus	84.30	0.00e+00	1157.00
IUUC-Bol-016597	Brassica oleracea	24.73	9.00e-03	35.00
IUUC-Cja-018904	Callithrix jacchus	90.95	0.00e+00	1080.00
IUUC-Cfa-021279	Canis familiaris	86.90	0.00e+00	1179.00
IUUC-Cpo-021857	Cavia porcellus	83.12	0.00e+00	1123.00
IUUC-Cre-022873	Chlamydomonas reinhardtii	25.00	1.20e+00	29.30
IUUC-Csa-023278	Chlorocebus sabaeus	95.47	0.00e+00	1275.00
IUUC-Cho-025002	Choloepus hoffmanni	89.43	6.00e-123	434.00
IUUC-Dre-028822	Danio rerio	61.40	2.00e-20	94.70
IUUC-Dno-029930	Dasypus novemcinctus	84.39	0.00e+00	1084.00
IUUC-Dor-031008	Dipodomys ordii	73.60	3.00e-171	595.00
IUUC-Ete-032370	Echinops telfairi	74.51	0.00e+00	961.00
IUUC-Eca-033353	Equus caballus	86.68	0.00e+00	845.00
IUUC-Eeu-034724	Erinaceus europaeus	68.26	0.00e+00	775.00
IUUC-Fca-035721	Felis catus	86.94	0.00e+00	1182.00
IUUC-Fal-036888	Ficedula albicollis	43.54	4.00e-111	395.00
IUUC-Gga-040932	Gallus gallus	43.71	2.00e-61	230.00
IUUC-Ggo-045465	Gorilla gorilla	97.88	0.00e+00	1308.00
IUUC-Hsa-045760	Homo sapiens	98.44	0.00e+00	1320.00
IUUC-Itr-048407	Ictidomys tridecemlineatus	92.37	3.00e-168	583.00
IUUC-Lch-050225	Latimeria chalumnae	35.05	1.00e-78	287.00
IUUC-Loc-052879	Lepisosteus oculatus	29.79	9.00e-39	154.00
IUUC-Laf-053871	Loxodonta africana	82.70	0.00e+00	1054.00
IUUC-Mcc-055478	Macaca mulatta	95.46	0.00e+00	1272.00
IUUC-Meu-056617	Macropus eugenii	49.19	1.00e-127	450.00
IUUC-Mga-059771	Meleagris gallopavo	43.34	1.00e-88	320.00
IUUC-Mmr-061450	Microcebus murinus	86.44	0.00e+00	1123.00
IUUC-Mdo-061927	Monodelphis domestica	54.83	0.00e+00	634.00
IUUC-Mmu-063821	Mus musculus	75.46	0.00e+00	973.00
IUUC-Mpu-065921	Mustela putorius furo	87.18	0.00e+00	1053.00
IUUC-Mlu-067296	Myotis lucifugus	83.12	0.00e+00	1061.00
IUUC-Nle-069257	Nomascus leucogenys	97.02	0.00e+00	1286.00
IUUC-Opr-071016	Ochotona princeps	72.51	0.00e+00	902.00
IUUC-Ont-071282	Oreochromis niloticus	31.38	4.00e-20	92.80
IUUC-Ocu-074580	Oryctolagus cuniculus	86.40	0.00e+00	1154.00
IUUC-Olo-080293	Oryza longistaminata	32.81	3.00e-03	35.00
IUUC-Oga-088521	Otolemur garnettii	85.16	0.00e+00	1117.00
IUUC-Pan-092193	Papio anubis	91.32	0.00e+00	1253.00
IUUC-Pfo-096691	Poecilia formosa	62.50	8.00e-19	89.00
IUUC-Pab-098460	Pongo abelii	95.76	0.00e+00	1283.00
IUUC-Pca-100892	Procavia capensis	73.66	0.00e+00	978.00
IUUC-Pva-102816	Pteropus vampyrus	83.21	0.00e+00	999.00
IUUC-Rno-105049	Rattus norvegicus	71.04	0.00e+00	924.00
IUUC-Sha-106502	Sarcophilus harrisii	54.42	1.00e-151	530.00
IUUC-Sar-113108	Sorex araneus	66.23	1.00e-141	496.00
IUUC-Ssc-115306	Sus scrofa	85.07	0.00e+00	1094.00
IUUC-Tgu-116746	Taeniopygia guttata	44.08	9.00e-89	320.00
IUUC-Tsy-119018	Tarsius syrichta	62.32	1.00e-166	579.00
IUUC-Tbe-127389	Tupaia belangeri	84.41	0.00e+00	654.00
IUUC-Ttr-128880	Tursiops truncatus	79.50	2.00e-138	486.00
IUUC-Xtr-132854	Xenopus tropicalis	34.53	2.00e-73	270.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence