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Tag Content
iUUCD ID IUUC-Aml-002263
Ensembl Protein ID ENSAMEP00000015438.1
UniProt Accession D2H3L6; D2H3L6_AILME
Genbank Protein ID EFB26875.1
Protein Name Tyrosine-protein kinase
Genbank Nucleotide ID ACTA01017606
Gene Name ABL2; PANDA_004303
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSAMEG00000014636.1 ENSAMET00000016081.1 ENSAMEP00000015438.1
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 2.00e-12 46.9 36 93
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++q+++W +     ++ +G +P+n+++ ++
   Q: 36   PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNQNGEWSEV--RSKNGQGWVPSNYITPVN 93
           67899************************.*********98..788899*********997 PP
   
Organism Ailuropoda melanoleuca
Protein Sequence
(Fasta)
EALHRPYGCD VEPQALNEAI RWSSKENLLG ATESDPNLFV ALYDFVASGD NTLSITKGEK 60
LRVLGYNQNG EWSEVRSKNG QGWVPSNYIT PVNSLEKHSW YHGPVSRSAA EYLLSSLING 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Aml-002263|UBD,SH3|Ailuropoda melanoleuca
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAAGCTTTAC ACCGCCCCTA TGGTTGTGAT GTTGAACCCC AGGCACTGAA CGAAGCCATC 60
AGGTGGAGCT CCAAGGAGAA CTTACTTGGA GCCACTGAGA GTGACCCTAA TCTCTTTGTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Aml-002263|UBD,SH3|Ailuropoda melanoleuca
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase
Interpro

IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3
Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1
PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE
SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc
Gene Ontology

GO:0005623--C:cell
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0030145--F:manganese ion binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0071300--P:cellular response to retinoic acid
GO:0007204--P:positive regulation of cytosolic calcium ion concentration
GO:0010976--P:positive regulation of neuron projection development
GO:0051353--P:positive regulation of oxidoreductase activity
GO:0010863--P:positive regulation of phospholipase C activity
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Atr-002778 Amborella trichopoda 32.49 1.00e-22 102.00
IUUC-Apl-003389 Anas platyrhynchos 85.75 0.00e+00 1751.00
IUUC-Ame-010629 Astyanax mexicanus 58.35 0.00e+00 1071.00
IUUC-Bta-013370 Bos taurus 96.84 0.00e+00 1994.00
IUUC-Cja-018894 Callithrix jacchus 96.57 0.00e+00 1994.00
IUUC-Cfa-020398 Canis familiaris 99.67 0.00e+00 1259.00
IUUC-Cpo-022367 Cavia porcellus 94.75 0.00e+00 1532.00
IUUC-Csa-023386 Chlorocebus sabaeus 97.11 0.00e+00 2001.00
IUUC-Cho-024714 Choloepus hoffmanni 91.97 0.00e+00 1886.00
IUUC-Dre-027741 Danio rerio 67.59 0.00e+00 1378.00
IUUC-Dno-029246 Dasypus novemcinctus 96.30 0.00e+00 1987.00
IUUC-Dor-030416 Dipodomys ordii 88.10 0.00e+00 1781.00
IUUC-Ete-032899 Echinops telfairi 77.58 0.00e+00 849.00
IUUC-Eca-033387 Equus caballus 97.57 0.00e+00 1976.00
IUUC-Eeu-035058 Erinaceus europaeus 86.93 0.00e+00 1831.00
IUUC-Fca-036578 Felis catus 90.04 0.00e+00 1807.00
IUUC-Fal-037491 Ficedula albicollis 88.40 0.00e+00 1876.00
IUUC-Gmo-038509 Gadus morhua 77.36 0.00e+00 1128.00
IUUC-Gga-040638 Gallus gallus 87.67 0.00e+00 1825.00
IUUC-Gac-042550 Gasterosteus aculeatus 78.03 0.00e+00 1180.00
IUUC-Ggo-044487 Gorilla gorilla 96.84 0.00e+00 1995.00
IUUC-Hsa-046636 Homo sapiens 96.93 0.00e+00 1995.00
IUUC-Itr-048685 Ictidomys tridecemlineatus 95.85 0.00e+00 1976.00
IUUC-Lch-049530 Latimeria chalumnae 78.37 0.00e+00 1582.00
IUUC-Loc-051933 Lepisosteus oculatus 70.81 0.00e+00 1437.00
IUUC-Laf-053802 Loxodonta africana 96.58 0.00e+00 2019.00
IUUC-Mcc-054836 Macaca mulatta 97.20 0.00e+00 2006.00
IUUC-Mga-059277 Meleagris gallopavo 88.03 0.00e+00 1838.00
IUUC-Mmr-061206 Microcebus murinus 96.03 0.00e+00 1903.00
IUUC-Mdo-062281 Monodelphis domestica 97.07 0.00e+00 1210.00
IUUC-Mmu-063847 Mus musculus 93.97 0.00e+00 1870.00
IUUC-Mpu-066309 Mustela putorius furo 99.67 0.00e+00 1260.00
IUUC-Mlu-068070 Myotis lucifugus 96.48 0.00e+00 1996.00
IUUC-Nle-070062 Nomascus leucogenys 99.02 0.00e+00 1251.00
IUUC-Opr-070534 Ochotona princeps 90.91 0.00e+00 1058.00
IUUC-Ont-072440 Oreochromis niloticus 66.67 0.00e+00 1333.00
IUUC-Oan-073526 Ornithorhynchus anatinus 88.76 0.00e+00 1768.00
IUUC-Ocu-074051 Oryctolagus cuniculus 94.95 0.00e+00 1887.00
IUUC-Oin-079172 Oryza indica 34.39 1.00e-23 105.00
IUUC-Olo-080286 Oryza longistaminata 34.39 1.00e-23 105.00
IUUC-Opu-083538 Oryza punctata 34.84 2.00e-23 104.00
IUUC-Oru-084741 Oryza rufipogon 34.39 8.00e-24 105.00
IUUC-Osa-085779 Oryza sativa 34.39 9.00e-24 105.00
IUUC-Ola-086752 Oryzias latipes 95.27 0.00e+00 915.00
IUUC-Oga-088767 Otolemur garnettii 90.65 0.00e+00 1796.00
IUUC-Oar-089800 Ovis aries 96.84 0.00e+00 1999.00
IUUC-Ptr-090857 Pan troglodytes 99.19 0.00e+00 1252.00
IUUC-Pan-092279 Papio anubis 97.02 0.00e+00 1994.00
IUUC-Psi-093573 Pelodiscus sinensis 88.41 0.00e+00 1805.00
IUUC-Pfo-096543 Poecilia formosa 77.01 0.00e+00 1145.00
IUUC-Pab-097949 Pongo abelii 96.93 0.00e+00 1956.00
IUUC-Pca-100370 Procavia capensis 94.66 0.00e+00 1475.00
IUUC-Pva-103220 Pteropus vampyrus 89.37 0.00e+00 1712.00
IUUC-Rno-105924 Rattus norvegicus 92.43 0.00e+00 1871.00
IUUC-Sha-107114 Sarcophilus harrisii 87.46 0.00e+00 1394.00
IUUC-Sit-110444 Setaria italica 32.50 1.00e-18 88.60
IUUC-Ssc-115968 Sus scrofa 96.03 0.00e+00 2038.00
IUUC-Tgu-117301 Taeniopygia guttata 87.85 0.00e+00 1793.00
IUUC-Tru-118410 Takifugu rubripes 68.48 0.00e+00 1369.00
IUUC-Tni-119991 Tetraodon nigroviridis 68.83 0.00e+00 1373.00
IUUC-Tbe-127362 Tupaia belangeri 91.52 0.00e+00 1793.00
IUUC-Ttr-129291 Tursiops truncatus 96.30 0.00e+00 1992.00
IUUC-Vpa-130800 Vicugna pacos 98.01 0.00e+00 1559.00
IUUC-Xtr-132965 Xenopus tropicalis 70.22 0.00e+00 1395.00
Created Date 25-Jun-2017

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