iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tae-125628

Ensembl Protein ID

TRIAE_CS42_4DL_TGACv1_346131_AA1155210.3

UniProt Accession

A0A1D5Y4R1; A0A1D5Y4R1_WHEAT

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIAE_CS42_4DL_TGACv1_346131_AA1155210	TRIAE_CS42_4DL_TGACv1_346131_AA1155210.1	TRIAE_CS42_4DL_TGACv1_346131_AA1155210.1
TRIAE_CS42_4DL_TGACv1_346131_AA1155210	TRIAE_CS42_4DL_TGACv1_346131_AA1155210.2	TRIAE_CS42_4DL_TGACv1_346131_AA1155210.2
TRIAE_CS42_4DL_TGACv1_346131_AA1155210	TRIAE_CS42_4DL_TGACv1_346131_AA1155210.3	TRIAE_CS42_4DL_TGACv1_346131_AA1155210.3
TRIAE_CS42_4DL_TGACv1_346131_AA1155210	TRIAE_CS42_4DL_TGACv1_346131_AA1155210.4	TRIAE_CS42_4DL_TGACv1_346131_AA1155210.4
TRIAE_CS42_4DL_TGACv1_346131_AA1155210	TRIAE_CS42_4DL_TGACv1_346131_AA1155210.5	TRIAE_CS42_4DL_TGACv1_346131_AA1155210.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	5.80e-169	565.3	455	942

Active Site

Position(s)	Description	Evidence
636	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLf 64
           YD Qi ++G++ q+k++ +++++vG g+lGcE+lKn++l+Gv     g++t++D+d +e+snl+rqFLf
   Q: 455  YDAQISVFGSKLQKKMRDSNIFVVGSGALGCEFLKNFALMGVscgrkGKLTITDDDVIEKSNLSRQFLF 523
           ********************************************************************* PP
   S: 65   raedvgksKAevaaealkelnpdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlc 130
           r++++g+ K+ vaa a+  +n+  +++a +++ ++++e+++   F + +d V++aldn+ ar++++ +c
   Q: 524  RDWNIGQAKSTVAATAASAINSCLHIDALQNRACPETEHVFndaFWEGLDAVINALDNVNARMYMDMRC 592
           ***************************************99999************************* PP
   S: 131  lnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa......... 190
           l+ ++pl+esgtlG + +++ +i++lte y +s+dpp+k++P+ct+ ++p +++h+++wa         
   Q: 593  LYFQKPLLESGTLGPKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFPHNIDHCLTWArsefeglle 661
           ********************************************************************* PP
   S: 191  ...vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikql 256
                +n ++++ a+      k   ++ +e +++v++ l +e+ + fe++i++a+ +f+ +++n +kql
   Q: 662  ktpNEVNSFMSNPAEYAAAMRKAGDAQARELLERVRECLDKERCDKFEDCIAWARLKFEDYFSNRVKQL 730
           9997888888888888888888899999***************************************** PP
   S: 257  lksfecdivtkskspfwv................................................... 274
           +  f+ d  t+ ++pfw+                                                   
   Q: 731  TFTFPEDAATSTGAPFWSapkrfprpvqfsavdsshiqfilsasilravsfgipipdwakntgnladiv 799
           ***********************************************************9999988888 PP
   S: 275  ......sfcsna.ealqvpekvekdeevvkasap..lylllralerfekk..kgrkpgelsfekddds. 331
                 +f++ +  +++++ek++    ++ ++ +  ++ ll++le  +kk  +g +++ ++fekddd  
   Q: 800  skvavpEFEPKSgVKIETDEKATNLSSASVDD-AavIEDLLTKLEACAKKlpSGFQMKPIQFEKDDDTn 867
           88877744443314444444444444433333.2589999999999999866899************** PP
   S: 332  .avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplkn 397
            ++dl++ +an+ra ++gi+  +d+ + k iag+iipaiatt+a+  Gl+++E++Kv+ g  + e ++n
   Q: 868  fHMDLIAGLANMRARNYGIQV-VDKLKAKFIAGRIIPAIATTTAMATGLVCLELYKVLAGdhPVEDYRN 935
           *********************.*************************************9989999*** PP
   S: 398  fflfdae 404
           +f ++a+
   Q: 936  TFANLAL 942
           **99875 PP

Organism

Triticum aestivum

Protein Sequence
(Fasta)

MLPTKRADGA EDSGDAAAKK ARVGESPAEA GSEAMVAGEP VGGGSNGNGV AEIDEDLHSR 60
QLAVYGRETM RLLFASNVLV SGLNGLGAET AKNLALAGVK SVTLHDVENV DMWDLSGNFF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCCCCAAGC CTCTCCACCG CGCCGCATCG GCGACTCAAT CCAACGCCAC CACCTTGCGC 60
CTTGCCTTGC CGCAAAACCC CAGTCTATAT ATACGCCATT CCACCGGCTT CGCCCCCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Hvu-047846	Hordeum vulgare	97.82	0.00e+00	1981.00
IUUC-Lpe-051520	Leersia perrieri	88.80	0.00e+00	1847.00
IUUC-Oba-075913	Oryza barthii	89.19	0.00e+00	1818.00
IUUC-Ogl-077371	Oryza glaberrima	89.19	0.00e+00	1815.00
IUUC-Ogu-078793	Oryza glumaepatula	89.19	0.00e+00	1815.00
IUUC-Oin-079710	Oryza indica	89.29	0.00e+00	1813.00
IUUC-Olo-080255	Oryza longistaminata	88.89	0.00e+00	1813.00
IUUC-Ome-081171	Oryza meridionalis	88.99	0.00e+00	1812.00
IUUC-Oni-082436	Oryza nivara	89.19	0.00e+00	1815.00
IUUC-Opu-083161	Oryza punctata	88.32	0.00e+00	1789.00
IUUC-Oru-085015	Oryza rufipogon	87.22	0.00e+00	1832.00
IUUC-Osa-085455	Oryza sativa	87.03	0.00e+00	1827.00
IUUC-Ptr-090609	Pan troglodytes	39.59	0.00e+00	682.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence