iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ogu-078115

Ensembl Protein ID

OGLUM08G22520.1

UniProt Accession

A0A0E0AXY3; A0A0E0AXY3_9ORYZ

Protein Name

Ubiquitinyl hydrolase 1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
OGLUM08G22520	OGLUM08G22520.1	OGLUM08G22520.1
OGLUM08G22520	OGLUM08G22520.2	OGLUM08G22520.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.70e-58	197.8	736	1257

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgyeqq 90
           tG+ NlgNtCY+N++LQcL+ + +lr  +l      l       p+g l + l++lf      ++ ++  +p +ll++++   ++f+g + q
   Q: 736  TGMPNLGNTCYLNALLQCLLVLGKLRARILG-----L-----GAPSGVLGDLLHDLFVDTNgpSYAQRLLDPAMLLRCVRFHYPQFRGIAMQ 817
           79*****************************.....4.....357899**********99999***************************** PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeet 182
           D++E+l++l d+l+e+    ++++             ++++  +    +++i+ +F gql+ ++ c+ c  +s +ee f dls+p+p k + 
   Q: 818  DCHELLCCLRDGLDEDE---RKWRA-----------GKMQQGAPSAVAPTVIDSIFAGQLSVTLSCKCCSFKSDSEEVFHDLSMPLPPKGTP 895
           *****************...23333...........344566799999*****************************************988 PP
   S: 183  kke......................................................................................... 185
           + +                                                                                         
   Q: 896  ARSvaspprngrcisqqktrmelfpainktntekihaiseggdaqvpasesehmvmvktseplevdsnhleqisqskgdvhgplqaptreen 987
           8889**************************************************************************************** PP
   S: 186  ..............................................................slqdcLesftkeeelegenkyycekck... 212
                                                                         s++++Le   k+e++e+     ce+c    
   Q: 988  tliasghgvertvsavldsikpedsieakmdtlsaevatedkgkdrnrdavydkaddinslaSIEEILELHLKAEMIEK----RCENCSnad 1075
           ******************************************************************************5....899999777 PP
   S: 213  ...............................................kkqe............aekklklkklPevLilhLkRfsfseeqks 245
                                                             e            a k++ ++klP+vL lhLkR  +      
   Q: 1076 qkaspisgkhgeqpvactnvngtvdgdqdeqdqgrgkqvnmghsahqV--EenqydrpdrnkgAIKTCLFSKLPPVLALHLKRNLWP----L 1161
           777777777777777777777777777766666666666666655550..0555666666666*********************774....5 PP
   S: 246  rekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn.....ekgk....WllfdDskVtevkeeevleetg 327
           + k++ +v+f+++Ld++ f++ ++ ++k++ +Y+L++vv H G  ++ GH+vayv+      +  +    W++ +D  ++ev+ eevl+   
   Q: 1162 KLKVSGHVSFKETLDVKLFMHPSS-EDKDNSSYRLVGVVEHLGlCMDAGHFVAYVRPscpqqT--NgsslWFCASDADIREVSLEEVLK--- 1247
           589**************9999855.5567****************************666542..14689*******************... PP
   S: 328  staYvlfYkr 337
           ++aY+lfY+r
   Q: 1248 CEAYLLFYER 1257
           ********98 PP

Organism

Oryza glumaepatula

Protein Sequence
(Fasta)

MDSRRPLLIP NEGDEPPPQP PEPPLAGVSD FRGRPVYRAT SGGWRSALFV AVLEMGCSFS 60
YYGVSANLIS YLTGPMGQSN ASAAAAANAW SGTARMLPLL GAVLADSFLG RYPSILLACT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAGTC GCCGTCCCTT GCTTATTCCG AATGAGGGTG ACGAGCCGCC GCCGCAGCCG 60
CCGGAGCCGC CGCTCGCCGG CGTGTCCGAC TTCCGAGGGC GGCCGGTCTA CCGCGCCACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0472--Membrane
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR020846--MFS_dom
IPR001394--Peptidase_C19_UCH
IPR000109--POT_fam
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00854--PTR2
PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0005215--F:transporter activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Oba-075277	Oryza barthii	95.60	3.00e-156	544.00
IUUC-Ogl-077731	Oryza glaberrima	96.71	0.00e+00	756.00
IUUC-Olo-080961	Oryza longistaminata	84.92	0.00e+00	679.00
IUUC-Oni-082715	Oryza nivara	98.07	0.00e+00	1344.00
IUUC-Opu-083257	Oryza punctata	85.09	0.00e+00	1179.00
IUUC-Oru-085100	Oryza rufipogon	91.02	0.00e+00	2036.00
IUUC-Osa-085491	Oryza sativa	97.44	0.00e+00	743.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence